A drug used to treat hypercalcemia (high blood levels of calcium) caused by certain types of cancer. It is also used with other anticancer drugs to treat multiple myeloma and breast cancer that has spread to bone. It is also used to treat Paget disease of the bone. Pamidronate disodium may help keep bone from breaking down and prevent the loss of calcium from the bones. It is a type of bisphosphonate. Also called Aredia.