News and events from NCI-funded research and programs
News & Events
Recent Press Releases
- Near-atomic resolution of protein structure by electron microscopy holds promise for drug discovery
May 7, 2015
An imaging technique, cryo-electron microscopy, can view in near-atomic detail the architecture of an enzyme bound to a drug that blocks its activity.
- Insights into a signaling process that enhances the effectiveness of cancer immunotherapy
May 4, 2015
Researchers have found that costimulatory signals can regulate T cell exhaustion, a process that limits the effectiveness of cancer immunotherapies.
- Multi-center anal pre-cancer treatment and cancer prevention study launched in HIV-infected persons
April 29, 2015
NCI has launched a multicenter phase III clinical trial called the ANCHOR Study -- Anal Cancer HSIL (High-grade Squamous Intraepithelial Lesion) Outcomes Research Study -- to determine if treatment of HSIL in HIV-infected individuals can prevent anal cancer from developing.
- A higher than expected fraction of adolescent osteosarcoma patients carry a gene mutation that is often inherited
April 20, 2015
A new study shows that inherited variations in a known tumor suppressor gene among children and adolescents with osteosarcoma, a cancer of the bone, are more common than previously thought.
- Researchers report initial feasibility of identifying patients who are exceptional responders to cancer therapy
April 19, 2015
A pilot study evaluating identification of cancer patients who respond to treatment that is ineffective in at least 90 percent of patients found that it was indeed able to confirm a majority of proposed patients as exceptional responders based on clinical data submitted for consideration. Being able to identify which patients are actual exceptional responders is an important step in determining why these patients respond so uniquely.
- Study reports peak longevity benefit with an hour of daily exercise
April 6, 2015
People who engage in three to five times the recommended minimum level of leisure-time physical activity derive the greatest benefit in terms of mortality reduction when compared with people who do not engage in leisure-time physical activity.
- Douglas Lowy named Acting Director of the National Cancer Institute
April 1, 2015
Douglas Lowy, M.D., today was officially named the National Cancer Institute’s Acting Director. Dr. Lowy, a cancer researcher for more than 40 years, received the National Medal of Technology and Innovation from President Obama in 2014 for his research that led to the development of the human papillomavirus (HPV) vaccine.
- Circulating tumor DNA in blood can predict recurrence of the most common type of lymphoma
April 1, 2015
Measurement of circulating tumor DNA in blood can be used to detect disease recurrence in patients with a curable form of cancer known as diffuse large B-cell lymphoma (DLBCL). In most patients, measurement of ctDNA enabled detection of microscopic disease before it could be seen on computerized tomography scans.
- New analysis of breast cancer subtypes could lead to better risk stratification; Annual Report to the Nation shows that mortality and incidence for most cancers continue to decline
March 30, 2015
For the first time, researchers have used national data to determine the incidence of the four major molecular subtypes of breast cancer by age, race/ethnicity, poverty level, and several other factors. The report showed continuing declines in cancer deaths for both men and women, for children, and for nearly all major cancer sites.
- Indicators related to lung cancer recurrence, metastases and survival can inform treatment of patients
March 23, 2015
This study describes prognostic factors for lung cancer spread and recurrence, as well as subsequent risk of death from the disease. The investigators observed that regardless of cancer stage, grade, or type of lung cancer, patients in the study were more likely to have distant metastasis than local recurrence.