News and events from NCI-funded research and programs
News & Events
Recent Press Releases
- TCGA study improves understanding of genetic drivers of cutaneous melanoma
June 18, 2015
A comprehensive analysis of the genome of cutaneous melanoma has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive the development of this disease.
- Genomic underpinnings of brain tumors expanded
June 10, 2015
TCGA researchers analyzed nearly 300 cases of diffuse low- and intermediate-grade gliomas, which together comprise lower-grade gliomas. LGGs occur mainly in adults and include astrocytomas, oligodendrogliomas and oligoastrocytomas.
- Benefit of fewer than three doses of HPV vaccine reported
June 10, 2015
Analysis of two independent HPV trials find benefit from fewer than 3 doses of the of the HPV 16/18 AS04-adjuvanted vaccine (Cervarix®).
- NCI-MATCH trial will link targeted cancer drugs to gene abnormalities
June 1, 2015
Investigators for the nationwide trial, NCI-MATCH: Molecular Analysis for Therapy Choice, announced that the trial will seek to determine whether targeted therapies for people whose tumors have specific gene mutations will be effective regardless of their cancer type. NCI-MATCH will incorporate more than 20 different study drugs or drug combinations, each targeting a specific gene mutation, in order to match each patient in the trial with a therapy that targets a molecular abnormality in their tumor.
- Near-atomic resolution of protein structure by electron microscopy holds promise for drug discovery
May 7, 2015
An imaging technique, cryo-electron microscopy, can view in near-atomic detail the architecture of an enzyme bound to a drug that blocks its activity.
- Insights into a signaling process that enhances the effectiveness of cancer immunotherapy
May 4, 2015
Researchers have found that costimulatory signals can regulate T cell exhaustion, a process that limits the effectiveness of cancer immunotherapies.
- Multi-center anal pre-cancer treatment and cancer prevention study launched in HIV-infected persons
April 29, 2015
NCI has launched a multicenter phase III clinical trial called the ANCHOR Study -- Anal Cancer HSIL (High-grade Squamous Intraepithelial Lesion) Outcomes Research Study -- to determine if treatment of HSIL in HIV-infected individuals can prevent anal cancer from developing.
- A higher than expected fraction of adolescent osteosarcoma patients carry a gene mutation that is often inherited
April 20, 2015
A new study shows that inherited variations in a known tumor suppressor gene among children and adolescents with osteosarcoma, a cancer of the bone, are more common than previously thought.
- Researchers report initial feasibility of identifying patients who are exceptional responders to cancer therapy
April 19, 2015
A pilot study evaluating identification of cancer patients who respond to treatment that is ineffective in at least 90 percent of patients found that it was indeed able to confirm a majority of proposed patients as exceptional responders based on clinical data submitted for consideration. Being able to identify which patients are actual exceptional responders is an important step in determining why these patients respond so uniquely.
- Study reports peak longevity benefit with an hour of daily exercise
April 6, 2015
People who engage in three to five times the recommended minimum level of leisure-time physical activity derive the greatest benefit in terms of mortality reduction when compared with people who do not engage in leisure-time physical activity.