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results found for:
Carboplatin
carboplatin
[ Carboplatin Hexal; Carboplatino ]
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A second-generation platinum compound with a broad spectrum of antineoplastic properties. Carboplatin contains a platinum atom complexed with two ammonia groups and a cyclobutane-dicarboxyl residue. This agent is activated intracellularly to form reactive platinum complexes that bind to nucleophilic groups such as GC-rich sites in DNA, thereby inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These carboplatin-induced DNA and protein effects result in apoptosis and cell growth inhibition. This agent possesses tumoricidal activity similar to that of its parent compound, cisplatin, but is more stable and less toxic. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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carboplatin-Taxol regimen
[ carboplatin-paclitaxel regimen ]
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A chemotherapy regimen consisting of carboplatin and paclitaxel (Taxol) used for the treatment of endometrial, epithelial ovarian, head and neck, and advanced-stage non-small cell lung cancers. (NCI Thesaurus)
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carboplatin-Taxol-bevacizumab regimen
[ carboplatin-paclitaxel-bevacizumab regimen ]
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A chemoimmunotherapy regimen consisting of carboplatin, paclitaxel (Taxol) and bevacizumab used for the treatment of advanced-stage, nonsquamous non-small cell lung cancer. (NCI Thesaurus)
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JEB regimen
[ carboplatin-etoposide-bleomycin regimen ]
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A chemotherapy regimen consisting of carboplatin (JM8), etoposide and bleomycin used for the treatment of childhood extracranial germ cell tumors. (NCI Thesaurus)
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