Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery

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Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentClosed18 and overNCI, OtherRTOG 1005
NCI-2011-02669, CDR0000700069, NCT01349322

Trial Description

Summary

RATIONALE: It is not yet know whether higher per daily radiation therapy is equally as effective as standard per daily radiation therapy in treating breast cancer.

PURPOSE: This randomized phase III trial studies how well an accelerated course of higher per daily radiation therapy with concomitant boost works compared to standard per daily radiation therapy with a sequential boost in treating patients with early-stage breast cancer that was removed by surgery.

Further Study Information

OBJECTIVES:

Primary

  • To determine whether an accelerated course of hypofractionated whole-breast irradiation (WBI) including a concomitant boost to the tumor bed in 15 fractions following lumpectomy will prove to be non-inferior in local control to a regimen of standard WBI with a sequential boost following lumpectomy for early-stage breast cancer patients.

Secondary

  • To determine whether breast-related symptoms and cosmesis from accelerated WBI that is hypofractionated (in only 3 weeks) with a concomitant boost is non-inferior to standard WBI with sequential boost.
  • To determine whether the risk of late cardiac toxicity in patients with left-sided breast cancer treated with hypofractionation will be non-inferior to conventional fractionated radiation therapy (RT) based upon analysis of radiation dosimetry from CT-based treatment planning and NTCP calculations.
  • To determine whether CT-based conformal methods intensity-modulated radiation therapy (IMRT) and three-dimensional conformal radiotherapy (3D-CRT) for WBI are feasible in a multi-institutional setting following lumpectomy in early-stage breast cancer patients and whether dose-volume analyses can be established to assess treatment adequacy and likelihood of toxicity.
  • To determine that cosmetic results and breast-related symptoms 3 years after hypofractionated breast radiation with concomitant boost will not be inferior to that obtained 3 years after WBI with sequential boost.
  • To determine whether future correlative studies can identify individual gene expressions and biological host factors associated with toxicity and/or local recurrence from standard and hypofractionated WBI.
  • If shown to be non-inferior, to then determine if accelerated course of hypofractionated WBI including a concomitant boost to the tumor bed in 15 fractions following lumpectomy will prove to be superior in local control to a regimen of standard WBI with a sequential boost following lumpectomy for early-stage breast cancer patients.
  • To determine whether treatment costs for hypofractionated WBI with concomitant boost are not higher than WBI with sequential boost.

OUTLINE: This is a multicenter study. Patients are stratified according to age (< 50 vs. ≥ 50 years), prior chemotherapy (yes vs. no), estrogen-receptor status (+ vs. -), and histology grade (1-2 vs. 3). Patients are randomized to 1 of 2 treatment arms. Treatment begins within 9 weeks of last surgery or chemotherapy delivery.

  • Arm I: Patients undergo standard whole-breast radiotherapy (WBI) comprising intensity-modulated radiation therapy (IMRT) or three-dimensional conformal radiotherapy (3D-CRT) 5 days a week for 3-5 weeks followed by a sequential radiotherapy boost to the lumpectomy area 5 days a week for 1-1½ weeks. Treatment continues in the absence of disease progression or unacceptable toxicity.
  • Arm II: Patients undergo accelerated hypofractionated WBI comprising IMRT or 3D-CRT with a concurrent boost to the lumpectomy area 5 days a week for 3 weeks. Treatment continues in the absence of disease progression or unacceptable toxicity.

Patients' tissue samples may be collected for future research studies.

After completion of study therapy, patients are followed at 1 month, at 6 months, and then yearly.

Eligibility Criteria

DISEASE CHARACTERISTICS:

  • Pathologically proven diagnosis of breast cancer resected by lumpectomy and whole-breast irradiation (WBI) with boost without regional nodal irradiation planned
  • Must meet one of the following three criteria:
  • pStage I or II breast cancer AND at least one of the following:
  • Age < 50 years or
  • Positive axillary nodes or
  • Lymphovascular space invasion (LVI) or
  • At least 2 close resection margins (> 0 mm to ≤ 2 mm) or
  • One close resection margin and extensive in-situ component (EIC) or
  • Focally positive resection margins or
  • Non-hormone-sensitive breast cancer (estrogen and progesterone receptor negative (ER- and PR-) or
  • Grade III histology or
  • Oncotype recurrence score > 25 or
  • pStage 0 breast cancer with nuclear grade 3 ductal carcinoma in situ (DCIS) and patient age < 50 years or
  • If multifocal breast cancer, then it must have been resected through a single lumpectomy incision with negative margins
  • Breast-conserving surgery with margins defined as follows:
  • Negative margins defined as no tumor at the resected specimen edge
  • Close resection margins > 0 mm to ≤ 2 mm as follows:
  • One close resection margin and EIC
  • Two or more close resection margins
  • A focally positive resection margin
  • Allowable options for mandatory axillary staging include:
  • Sentinel node biopsy alone (if sentinel node is negative, pN0, pN0[IHC-,+])
  • Sentinel node biopsy alone, OR followed by axillary node dissection, for clinically node-negative patients as described below:
  • Microscopic sentinel node (SN) positive (pN1mic)
  • One or two SNs positive (pN1) without extracapsular extension
  • Negative SN biopsy after neoadjuvant chemotherapy
  • Axillary node dissection is required following SN biopsy with a minimum total of 6 axillary nodes if any of the following exist:
  • For > 2 positive SN
  • Any positive SN biopsy after neoadjuvant chemotherapy
  • For clinically (by either imaging or examination) T3 disease
  • For extracapsular extension
  • Axillary dissection alone (with a minimum of 6 axillary nodes)
  • CT-imaging of the ipsilateral breast within 28 days of study entry for the radiation treatment planning.
  • Must be able to delineate on CT scan the extent of the target lumpectomy cavity for boost (placement of surgical clips to assist in treatment planning of the boost is strongly recommended)
  • No clinical evidence for distant metastases, based upon the following minimum diagnostic workup:
  • History/physical examination, including breast exam (inspection and palpation of the breasts) and documentation of weight and Zubrod Performance Status of 0-2 within 28 days prior to study entry
  • A mammogram of both right and left breast within only 1 time point of 90 days of the diagnostic biopsy establishing the diagnosis
  • No prior invasive or in-situ carcinoma of the breast (prior LCIS is eligible)
  • No American Joint Committee on Cancer (AJCC) pathologic T4, N2 or N3, or M1 breast cancer
  • Must not have two or more breast cancers that are not resectable through a single lumpectomy incision
  • Must not be DCIS and ≥ 50 years old
  • Must not be DCIS only (without an invasive component), nuclear grade 1 or 2 and < 50 years old
  • No suspicious unresected microcalcification, densities, or palpable abnormalities (in the ipsilateral or contralateral breast) unless biopsied and found to be benign
  • No non-epithelial breast malignancies such as sarcoma or lymphoma
  • No Paget disease of the nipple
  • No male breast cancer
  • Breast implants allowed

PATIENT CHARACTERISTICS:

  • ANC ≥ 1,800/mm³
  • Platelet count ≥ 75,000/mm³
  • Hemoglobin ≥ 8.0 g/dL (transfusion or other intervention to achieve Hgb ≥ 8.0 g/dL is acceptable)
  • Negative urine or serum pregnancy test within 14 days of study entry
  • Women of childbearing potential must not be pregnant or nursing and willing to use medically acceptable form of contraception during radiotherapy
  • No prior invasive non-breast malignancy (except non-melanomatous skin cancer or carcinoma in situ of the cervix) unless disease free for a minimum of 5 years prior to study entry
  • No severely active co-morbidity, defined as follows:
  • Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months
  • Transmural myocardial infarction within the past 6 months
  • Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration
  • Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy within 30 days before registration
  • Hepatic insufficiency resulting in clinical jaundice and/or coagulation defects; note, however, that laboratory tests for liver function and coagulation parameters are not required for entry into this protocol
  • Acquired Immune-Deficiency Syndrome (AIDS) based upon current CDC definition
  • HIV testing is not required for entry into this protocol
  • No active systemic lupus, erythematosus, or any history of scleroderma or dermatomyositis with active rash
  • Medical, psychiatric, or other condition that would prevent the patient from receiving the protocol therapy or providing informed consent

PRIOR CONCURRENT THERAPY:

  • See Disease Characteristics
  • Study entry must be within 50 days of last breast/axillary surgery and/or last chemotherapy
  • No treatment plan that includes regional-node radiotherapy
  • No prior radiotherapy to the breast or prior radiation to the region of the ipsilateral breast that would result in overlap of radiation therapy fields
  • No intention to administer concurrent chemotherapy for current breast cancer

Trial Contact Information

Trial Lead Organizations/Sponsors

Radiation Therapy Oncology Group

  • National Cancer Institute
  • NRG Oncology
Frank A. Vicini, MD, FACR, Principal Investigator
Gary M. Freedman, MD, Study Chair
Julia R. White, MD, Study Chair
Douglas W. Arthur, Study Chair

Trial Sites

U.S.A.

Alabama
Birmingham

Kirklin Clinic at Acton Road

Jennifer F De Los Santos
Ph: 205-934-0309

UAB Comprehensive Cancer Center

Ruby F. Meredith
Ph: 205-934-0309

Arizona
Scottsdale

21st Century Oncology - Scottsdale

Steven E Finkelstein
Ph: 888-823-5923
Email: ctsucontact@westat.com

Mayo Clinic Scottsdale

Ivy A. Petersen
Ph: 507-538-7623

Tucson

Arizona Cancer Center at University of Arizona Health Sciences Center

Victor J Gonzalez
Ph: 520-626-9008

Arizona Oncology - Tucson

Vivek S Kavadi
Ph: 281-277-5200

Arkansas
Little Rock

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences

V. Suzanne Klimberg
Ph: 501-686-8274

California
Auburn

Auburn Radiation Oncology

Christopher Jones
Ph: 916-454-6500
Email: cancerinfo@sutterhealth.org

Cameron Park

Radiation Oncology Centers - Cameron Park

Christopher Jones
Ph: 916-454-6500
Email: cancerinfo@sutterhealth.org

Carmichael

Mercy Cancer Center at Mercy San Juan Medical Center

Christopher Jones
Ph: 916-454-6500
Email: cancerinfo@sutterhealth.org

Chico

Enloe Cancer Center at Enloe Medical Center

Grace E Yuh
Ph: 530-332-3808

Duarte

City of Hope Comprehensive Cancer Center

Nayana L. Vora
Ph: 800-826-4673
Email: becomingapatient@coh.org

Dublin

Epic Care-Dublin

James H. Feusner
Ph: 510-450-7600

LA Jolla

Rebecca and John Moores UCSD Cancer Center

Loren K Mell
Ph: 858-822-5354
Email: cancercto@ucsd.edu

Los Angeles

Jonsson Comprehensive Cancer Center at UCLA

Susan A McCloskey
Ph: 888-798-0719

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center

Christiane M Burnison
Ph: 310-423-8965

USC/Norris Comprehensive Cancer Center and Hospital

Eugene I Chung
Ph: 323-865-0451

Eugene I Chung
Ph: 323-865-0451

Oakland

Kaiser Permanente-Oakland

Samantha A Seaward
Ph: 626-564-3455

Rancho Cardova

Kaiser Permanente Medical Center - Rancho Cordova

Samantha A Seaward
Ph: 626-564-3455

Rohnert Park

Rohnert Park Cancer Center

Samantha A Seaward
Ph: 626-564-3455

Roseville

Radiation Oncology Center - Roseville

Christopher Jones
Ph: 916-454-6500
Email: cancerinfo@sutterhealth.org

The Permanente Medical Group-Roseville Radiation Oncology

Samantha A Seaward
Ph: 626-564-3455

Sacramento

South Sacramento Cancer Center

Samantha A Seaward
Ph: 626-564-3455

Sutter Cancer Center

Christopher Jones
Ph: 916-454-6500
Email: cancerinfo@sutterhealth.org

University of California Davis Cancer Center

Jyoti S Mayadev
Ph: 916-734-3089

Santa Clara

Kaiser Permanente Medical Center - Santa Clara Homestead Campus

Samantha A Seaward
Ph: 626-564-3455

Louis Fehrenbacher
Ph: 626-564-3455

South Pasadena

City of Hope Medical Group, Incorporated

Nayana L. Vora
Ph: 800-826-4673
Email: becomingapatient@coh.org

South San Francisco

Kaiser Permanente Cancer Treatment Center

Samantha A Seaward
Ph: 626-564-3455

Vacaville

Solano Radiation Oncology Center

Christopher Jones
Ph: 916-454-6500
Email: cancerinfo@sutterhealth.org

Colorado
Aurora

University of Colorado Cancer Center at UC Health Sciences Center

Rachel A. Rabinovitch
Ph: 720-848-0650

Colorado Springs

Penrose Cancer Center at Penrose Hospital

Alan T Monroe
Ph: 888-785-6789

Denver

Porter Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Loveland

McKee Medical Center

Keren Sturtz
Ph: 888-785-6789

Connecticut
Hartford

Helen and Harry Gray Cancer Center at Hartford Hospital

Helaine F Bertsch
Ph: 860-545-5363

District of Columbia
Washington

Washington Cancer Institute at Washington Hospital Center

Pamela Randolph
Ph: 202-877-8839

Florida
Atlantis

JFK Medical Center

Georges F Hatoum
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Daytona Beach

Florida Hospital Memorial Medical Center

Ronald J Krochak
Ph: 386-676-6025

Deerfield Beach

University of Miami/Deerfield Beach

Cristiane Takita
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Gainesville

UF Health Cancer Center

R. Charles Nichols
Ph: 877-686-6009

Jacksonville

Baptist Cancer Institute - Jacksonville

Cynthia S Anderson
Ph: 904-202-7051

University of Florida Health Science Center - Jacksonville

R. Charles Nichols
Ph: 877-686-6009

Jascksonville

Integrated Community Oncology Network - Baptist South

Cynthia S Anderson
Ph: 904-202-7051

Miami

Jackson Memorial Hospital

Cristiane Takita
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

University of Miami Sylvester Comprehensive Cancer Center - Miami

Cristiane Takita
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Orange Park

Integrated Community Oncology Network - Orange Park

Cynthia S Anderson
Ph: 904-202-7051

Orlando

M.D. Anderson Cancer Center at Orlando

Tomas Dvorak
Ph: 321-841-7246

Palatka

Cancer Specialists of North Florida-Putnam

Cynthia S Anderson
Ph: 904-202-7051

Saint Augustine

Integrated Community Oncology Network at St. Augustine Cancer Center

Cynthia S Anderson
Ph: 904-202-7051

Tampa

H. Lee Moffitt Cancer Center and Research Institute at University of South Florida

Eleanor E.R. Harris
Ph: 252-744-2391
Email: canceranswers@moffitt.org

The Villages

The Villages Regional Hospital

Jorge E Freire
Ph: 352-751-8185

Georgia
Atlanta

Georgia Cancer Center for Excellence at Grady Memorial Hospital

Mylin A Torres
Ph: 404-778-1868

Northside Hospital Cancer Center

Sahar E Rosenbaum
Ph: 404-303-3355

Piedmont Hospital

Adam W Nowlan
Ph: 404-425-7943
Email: phri@piedmont.org

Saint Joseph's Hospital of Atlanta

Mylin A Torres
Ph: 404-778-1868

Winship Cancer Institute of Emory University

Mylin A Torres
Ph: 404-778-1868

Cumming

Northside Hospital-Forsyth

Sahar E Rosenbaum
Ph: 404-303-3355

Savannah

Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler

John A Pablo
Ph: 912-819-5704

Hawaii
Honolulu

Queen's Cancer Institute at Queen's Medical Center

Paul A. DeMare
Ph: 808-545-8548

Idaho
Boise

Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

Samir Narayan
Ph: 734-712-3456

Illinois
Chicago

Creticos Cancer Center at Advocate Illinois Masonic Medical Center

Paige L Dorn
Ph: 773-296-5360

Robert H. Lurie Comprehensive Cancer Center at Northwestern University

John P Hayes
Ph: 312-695-1301
Email: cancer@northwestern.edu

University of Chicago Cancer Research Center

Steven J Chmura
Ph: 773-834-7424

Decatur

Decatur Memorial Hospital Cancer Care Institute

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Freeport

Leonard C. Ferguson Cancer Center

Lauren Q Shapiro
Ph: 877-405-6866

Maywood

Cardinal Bernardin Cancer Center at Loyola University Medical Center

Tarita O Thomas
Ph: 708-226-4357

Normal

Community Cancer Center

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Park Ridge

Advocate Lutheran General Cancer Care Center

James E Ruffer
Ph: 847-842-4847

Peoria

OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC

Nguyet A Le-Lindqwister
Ph: 800-793-2262

OSF St. Francis Medical Center

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Rockford

Advanced Care and Treatment Medical Group, PC

Harvey Eric Einhorn
Ph: 779-696-9400
Email: cancercare@swedishamerican.org

Springfield

Cancer Institute at St. John's Hospital

Cathy L. Clausen
Ph: 217-525-5666
Email: diana.weyhenmeyer@st-johns.org

Warrenville

Central Dupage Cancer Center

Christy M Kesslering
Ph: 630-352-5300

Indiana
Anderson

Saint John's Health System

Alexander M. Yeh
Ph: 765-646-8358

Avon

Clarian West Medical Center

Peter A. Johnstone
Ph: 317-274-2552

Goshen

Center for Cancer Care at Goshen General Hospital

James A. Wheeler
Ph: 574-535-2858

Indianapolis

Community Regional Cancer Care at Community Hospital East

Shih J Wei
Ph: 317-621-7104

Community Regional Cancer Care at Community Hospital North

Shih J Wei
Ph: 317-621-7104

Indiana University Melvin and Bren Simon Cancer Center

Peter A. Johnstone
Ph: 317-274-2552

Mishawaka

Michiana Hematology-Oncology, PC - Mishawaka

David A. Hornback
Ph: 800-284-7370

Muncie

Cancer Center at Ball Memorial Hospital

Yunjie X Lin
Ph: 765-751-5850
Email: alpatterson@medicalconsultantspc.com

Iowa
Clive

Mercy Cancer Center - West Lakes

Robert J Behrens
Ph: 888-244-6061
Email: sherrijr@iora.org

Des Moines

John Stoddard Cancer Center at Iowa Methodist Medical Center

Robert J Behrens
Ph: 888-244-6061
Email: sherrijr@iora.org

Mercy Cancer Center at Mercy Medical Center - Des Moines

Robert J Behrens
Ph: 888-244-6061
Email: sherrijr@iora.org

Dubuque

Wendt Regional Cancer Center at Finley Hospital

Nagendra (Bobby) S Koneru
Ph: 800-397-2467
Email: cancer@northwestern.edu

Kansas
Kansas City

Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center

Parvesh Kumar
Ph: 913-588-4709

Lawrence

Lawrence Memorial Hospital

Shaker R. Dakhil
Ph: 316-262-4467

Overland Park

Kansas City Cancer Centers - Southwest

Parvesh Kumar
Ph: 913-588-4709

Prairie Village

CCOP - Kansas City

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Wichita

CCOP - Wichita

Shaker R. Dakhil
Ph: 316-262-4467

Via Christi Cancer Center at Via Christi Regional Medical Center

Shaker R. Dakhil
Ph: 316-262-4467

Kentucky
Lexington

University of Kentucky Chandler Medical Center

Jonathan M Feddock
Ph: 859-257-3379

Owensboro

Mitchell Memorial Cancer Center at Owensboro Medical Health System

Samuel R Faught
Ph: 270-688-3691
Email: shawns@omhs.org

Louisiana
New Orleans

Tulane Cancer Center at Tulane University Hospital and Clinic

William R. Robinson
Ph: 504-988-6121

Maryland
Annapolis

DeCesaris Cancer Institute at Anne Arundel Medical Center

Mary E Young
Ph: 443-481-1320
Email: kbodenhorn@aahs.org

Baltimore

Greater Baltimore Medical Center Cancer Center

Geoffrey A Neuner
Ph: 443-849-3706

Greenebaum Cancer Center at University of Maryland Medical Center

Steven Feigenberg
Ph: 800-888-8823

St. Agnes Hospital Cancer Center

Richard S. Hudes
Ph: 410-368-2910

Bethesda

National Naval Medical Center

John J O'Connell
Ph: 301-319-2100

Columbia

Central Maryland Oncology Center

Steven Feigenberg
Ph: 800-888-8823

Glen Burnie

Tate Cancer Center at Baltimore Washington Medical Center

Steven Feigenberg
Ph: 800-888-8823

Salisbury

Peninsula Regional Medical Center

Matthew L Snyder
Ph: 866-922-6237

Massachusetts
Boston

Boston University Cancer Research Center

Lisa A. Kachnic
Ph: 617-638-8265

Massachusetts General Hospital

Alphonse G Taghian
Ph: 877-726-5130

Lowell

Lowell General Hospital

Matthew S Katz
Ph: 978-788-7084
Email: ghincks@lowellgeneral.org

Newton

Newton-Wellesley Hospital

Alphonse G Taghian
Ph: 877-726-5130

Peabody

NSMC Cancer Center - Peabody

Alphonse G Taghian
Ph: 877-726-5130

Michigan
Ann Arbor

University of Michigan Comprehensive Cancer Center

Reshma Jagsi
Ph: 800-865-1125

Clarkston

21st Century Oncology-Clarkston

Jeffrey D. Forman
Ph: 248-858-6215

Clinton Township

Henry Ford Macomb Hospital

Eleanor M. Walker
Ph: 313-916-1784

Detroit

Josephine Ford Cancer Center at Henry Ford Hospital

Eleanor M. Walker
Ph: 313-916-1784

Van Elslander Cancer Center at St. John Hospital and Medical Center

Samir Narayan
Ph: 734-712-3456

Wayne State University

Steven R. Miller
Ph: 313-576-9363

Farmington

Botsford Oncology Practice at Botsford General Hospital

John M. Robertson
Ph: 248-551-7695

Farmington Hills

21st Century Oncology-Farmington Hills

Jeffrey D. Forman
Ph: 248-858-6215

Weisberg Cancer Treatment Center

Steven R. Miller
Ph: 313-576-9363

Flint

McLaren Cancer Institute

Hesham E. Gayar
Ph: 810-342-4071

Grand Rapids

Butterworth Hospital at Spectrum Health

Gilbert D Padula
Ph: 616-685-5225

Lacks Cancer Center at Saint Mary's Health Care

Gilbert D Padula
Ph: 616-685-5225

Kalamazoo

West Michigan Cancer Center

Raymond Sterling Lord
Ph: 269-373-7458

Monroe

KCC Radiation Oncology at Monroe Cancer Center

Steven R. Miller
Ph: 313-576-9363

Petoskey

Northern Michigan Hospital

Peter S Armstrong
Ph: 800-248-6777

Pontiac

St. Joseph Mercy Oakland

Samir Narayan
Ph: 734-712-3456

Royal Oak

William Beaumont Hospital - Royal Oak Campus

John M. Robertson
Ph: 248-551-7695

Troy

21st Century Oncology-Troy

Jeffrey D. Forman
Ph: 248-858-6215

William Beaumont Hospital - Troy Campus

John M. Robertson
Ph: 248-551-7695

Warren

St. John Macomb Hospital

Samir Narayan
Ph: 734-712-3456

Minnesota
Rochester

Mayo Clinic Cancer Center

Ivy A. Petersen
Ph: 507-538-7623

Saint Cloud

CentraCare Clinic - Women and Children

Barbi L. Kaplan-Frenkel
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Mississippi
Pascagoula

Regional Cancer Center at Singing River Hospital

James E. Clarkson
Ph: 228-809-5292

Missouri
Chesterfield

Saint Luke's Hospital

Donald F. Busiek
Ph: 314-205-6936

Kansas City

Kansas City Cancer Centers - North

Parvesh Kumar
Ph: 913-588-4709

Kansas City Cancer Centers - South

Parvesh Kumar
Ph: 913-588-4709

Lee's Summit

Kansas City Cancer Centers - East

Parvesh Kumar
Ph: 913-588-4709

Liberty

Parvin Radiation Oncology

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Saint Louis

Barnes-Jewish West County Hospital

Imran Zoberi
Ph: 800-600-3606
Email: info@ccadmin.wustl.edu

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

Imran Zoberi
Ph: 800-600-3606
Email: info@ccadmin.wustl.edu

Imran Zoberi
Ph: 800-600-3606
Email: info@ccadmin.wustl.edu

Saint Peters

Siteman Cancer Center at Barnes-Jewish St. Peters Hospital - St. Peters

Imran Zoberi
Ph: 800-600-3606
Email: info@ccadmin.wustl.edu

Montana
Billings

Billings Clinic Cancer Center - 801 N 29th Street

Benjamin Thomas Marchello
Ph: 800-648-6274

Great Falls

Benefis Sletten Cancer Institute

Benjamin Thomas Marchello
Ph: 800-648-6274

Kalispell

Kalispell Regional Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Nebraska
Omaha

Fred and Pamela Buffett Cancer Center

Andrew O Wahl
Ph: 800-999-5465

Methodist Estabrook Cancer Center

Tien-Shew W Huang
Ph: 402-354-5144

Nevada
Las Vegas

Radiation Oncology Centers of Las Vegas - Downtown Location

Raul T Meoz
Ph: 702-731-8274

Reno

Renown Institute for Cancer at Renown Regional Medical Center

Michael C Hardacre
Ph: 775-982-4400

Saint Mary's Regional Medical Center

Kathleen (Katie) B Legarza
Ph: 775-770-7410

New Hampshire
Lebanon

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center

Alan C. Hartford
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

New Jersey
Basking Ridge

Memorial Sloan-Kettering Cancer Center - Basking Ridge

Preeti K Parhar
Ph: 212-639-5007

Brick

Ocean Medical Center at Meridian Health

Douglas A Miller
Ph: 732-206-8384

Long Branch

Monmouth Medical Center

Mitchell F Weiss
Ph: 732-923-7689

Morristown

Carol G. Simon Cancer Center at Morristown Memorial Hospital

Mona Karim
Ph: 973-971-5900

Mount Holly

Virtua Fox Chase Health Cancer Program at Virtua Memorial Hospital Burlington County

Lemuel S. Ariaratnam
Ph: 888-847-8823

Neptune

Jersey Shore Cancer Center at Jersey Shore University Medical Center

Douglas A Miller
Ph: 732-206-8384

New Brunswick

Saint Peter's University Hospital

Gopal R Desai
Ph: 732-745-8600ext6163
Email: kcovert@saintpetersuh.com

Red Bank

Booker Cancer Center at Riverview Medical Center

Douglas A Miller
Ph: 732-206-8384

Sparta

Frederick R. and Betty M. Smith Cancer Treatment Center

Pramila Rani Anne
Ph: 215-955-6084

Toms River

J. Phillip Citta Regional Cancer Center at Community Medical Center

David J D'Ambrosio
Ph: 732-818-3882

Voorhees

Fox Chase Virtua Health Cancer Program at Virtua West Jersey

Lemuel S. Ariaratnam
Ph: 888-847-8823

New Mexico
Albuquerque

University of New Mexico Cancer Center

Thomas M Schroeder
Ph: 505-272-6972

Las Cruces

Memorial Medical Center

Thomas M Schroeder
Ph: 505-272-6972

New York
Albany

New York Oncology Hematology, PC - Albany

Vivek S Kavadi
Ph: 281-277-5200

Bronx

Montefiore Medical Center

Jana L Fox
Ph: 718-904-2730
Email: aecc@aecom.yu.edu

Buffalo

Roswell Park Cancer Institute

Kilian S May
Ph: 877-275-7724

Canandiaqua

Sands Cancer Center

Yuhchyau Chen
Ph: 585-275-5830

Commack

Memorial Sloan-Kettering Cancer Center

Preeti K Parhar
Ph: 212-639-5007

Cooperstown

Bassett Healthcare Regional Cancer Program at Mary Imogene Bassett Hospital

Joy E Anderson
Ph: 607-547-3073
Email: diana.crean@bassett.org

East Syracuse

CCOP - Hematology-Oncology Associates of Central New York

Dennis Jay Kotlove
Ph: 315-472-7504

New Hyde Park

Long Island Jewish Medical Center

Lucille N Lee
Ph: 516-562-3467

New York

Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center

Daniela Gidea-Addeo
Ph: 212-305-8615

Memorial Sloan-Kettering Cancer Center

Preeti K Parhar
Ph: 212-639-5007

Poughkeepsie

Hudson Valley Oncology Associates

Pramila Rani Anne
Ph: 215-955-6084

Rochester

Daisy Marquis Jones Radiation Oncology Center at Highland Hospital of Rochester

Yuhchyau Chen
Ph: 585-275-5830

James P. Wilmot Cancer Center at University of Rochester Medical Center

Yuhchyau Chen
Ph: 585-275-5830

University Radiation Oncology at Parkridge Hospital

Yuhchyau Chen
Ph: 585-275-5830

Rockville Centre

Memorial Sloan-Kettering Cancer Center - Rockville Centre

Preeti K Parhar
Ph: 212-639-5007

Sleepy Hollow

Memorial Sloan-Kettering Cancer Center at Phelps Memorial Hospital Center

Preeti K Parhar
Ph: 212-639-5007

White Plains

Dickstein Cancer Treatment Center at White Plains Hospital Center

Randy E Stevens
Ph: 914-681-2290

North Carolina
Durham

Duke Cancer Institute

Janet K Horton
Ph: 888-275-3853

Greenville

Leo W. Jenkins Cancer Center at ECU Medical School

Eleanor E.R. Harris
Ph: 252-744-2391
Email: canceranswers@moffitt.org

Morehead City

Coleman Radiation Oncology Center at Carter General Hospital

Michael A Papagikos
Ph: 910-251-1839

New Bern

CarolinaEast Cancer Care

Michael A Papagikos
Ph: 910-251-1839

Pinehurst

FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center

Charles S Kuzma
Ph: 910-715-2200

Statesville

Iredell Memorial Hospital

Ruby A. Grimm
Ph: 704-873-5661

Supply

South Atlantic Radiation Oncology, LLC

Michael A Papagikos
Ph: 910-251-1839

Wilmington

Coastal Carolina Radiation Oncology Center

Michael A Papagikos
Ph: 910-251-1839

Zimmer Cancer Center at New Hanover Regional Medical Center

Michael A Papagikos
Ph: 910-251-1839

North Dakota
Bismarck

Medcenter One Hospital Cancer Care Center

Preston D. Steen
Ph: 701-234-6161

Grand Forks

Altru Cancer Center at Altru Hospital

Grant R Seeger
Ph: 701-780-6520

Ohio
Akron

McDowell Cancer Center at Akron General Medical Center

Mitchell Lee Fromm
Ph: 330-344-6348

Summa Center for Cancer Care at Akron City Hospital

Charles A Kunos
Ph: 330-375-6101

Barberton

Barberton Citizens Hospital

Charles A Kunos
Ph: 330-375-6101

Chardon

Geauga Regional Hospital

Janice Lyons
Ph: 800-641-2422

Chillicothe

Adena Regional Medical Center

Mark J Becker
Ph: 614-566-4475

Cincinnati

Christ Hospital Cancer Center

Cornelia M McCluskey
Ph: 513-585-2859

University of Cincinnati

Kevin P. Redmond
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Cleveland

Case Comprehensive Cancer Center

Janice Lyons
Ph: 800-641-2422

Cleveland Clinic Cancer Center at Fairview Hospital

Rahul D Tendulkar
Ph: 866-223-8100

Cleveland Clinic Taussig Cancer Center

Rahul D Tendulkar
Ph: 866-223-8100

Columbus

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center

Julia R. White
Ph: 866-627-7616
Email: osu@emergingmed.com

Independence

Cleveland Clinic Taussig Cancer Center

Rahul D Tendulkar
Ph: 866-223-8100

Mayfield Heights

Hillcrest Cancer Center at Hillcrest Hospital

Rahul D Tendulkar
Ph: 866-223-8100

Medina

Summa Health Center at Lake Medina

Charles A Kunos
Ph: 330-375-6101

Mentor

Lake/University Ireland Cancer Center

Janice Lyons
Ph: 800-641-2422

Middleburg Heights

Southwest General Health Center

Janice Lyons
Ph: 800-641-2422

Orange Village

UHHS Chagrin Highlands Medical Center

Janice Lyons
Ph: 800-641-2422

Ravenna

Robinson Radiation Oncology

Mitchell Lee Fromm
Ph: 330-344-6348

Sandusky

North Coast Cancer Care, Incorporated

Rahul D Tendulkar
Ph: 866-223-8100

Strongsville

Cleveland Clinic Foundation - Strongsville

Rahul D Tendulkar
Ph: 866-223-8100

Westlake

UHHS Westlake Medical Center

Janice Lyons
Ph: 800-641-2422

Oklahoma
Oklahoma City

Stephenson Cancer Center at the University of Oklahoma

Terence S. Herman
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Tulsa

Natalie Warren Bryant Cancer Center at St. Francis Hospital

Charles E Stewart
Ph: 918-494-2200

Oregon
Clackamas

Clackamas Radiation Oncology Center

Matthew C Solhjem
Ph: 503-215-6412

Eugene

Willamette Valley Cancer Center - Eugene

Vivek S Kavadi
Ph: 281-277-5200

Grants Pass

Three Rivers Community Hospital

Gordon L. Metz
Ph: 541-789-6176

Medford

Dubs Cancer Center at Rogue Valley Medical Center

Gordon L. Metz
Ph: 541-789-6176

Providence Cancer Center at PMCC

Gordon L. Metz
Ph: 541-789-6176

Portland

Providence Cancer Center at Providence Portland Medical Center

Matthew C Solhjem
Ph: 503-215-6412

Pennsylvania
Abington

Rosenfeld Cancer Center at Abington Memorial Hospital

Wayne H Pinover
Ph: 215-481-2402

Beaver

UPMC Cancer Center at Beaver Medical Center

Sushil Beriwal
Ph: 412-647-2811

Bryn Mawr

Bryn Mawr Hospital

Albert S DeNittis
Ph: 866-225-5654

Clairton

UPMC Cancer Center at Jefferson Regional Medical Center

Sushil Beriwal
Ph: 412-647-2811

Danville

Geisinger Cancer Institute at Geisinger Health

Thomas J Gergel
Ph: 570-271-5251

Drexel Hill

Delaware County Regional Cancer Center at Delaware County Memorial Hospital

Rachelle M. Lanciano
Ph: 610-284-8237
Email: jolene.garney@crozer.org

Dunmore

Northeast Radiation Oncology Center

Pramila Rani Anne
Ph: 215-955-6084

East Stroudsburg

Dale and Frances Hughes Cancer Center at Pocono Medical Center

Pramila Rani Anne
Ph: 215-955-6084

Erie

Regional Cancer Center - Erie

Andrew T Figura
Ph: 814-838-0448
Email: mhaynes@trcc.org

Gettysburg

Adams Cancer Center

Amit B. Shah
Ph: 877-441-7957

Greensburg

UPMC Cancer Center - Arnold Palmer Pavilion

Sushil Beriwal
Ph: 412-647-2811

Hanover

Cherry Tree Cancer Center

Amit B. Shah
Ph: 877-441-7957

Hershey

Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center

Henry Wagner
Ph: 717-531-3779
Email: CTO@hmc.psu.edu

Johnstown

UPMC Cancer Center at the John P. Murtha Pavilion

Sushil Beriwal
Ph: 412-647-2811

Lancaster

Lancaster General Hospital

Jeffery S Eshleman
Ph: 717-544-5511

Langhorne

St. Mary Regional Cancer Center

Robert C. Reilly
Ph: 215-710-4585

McKeesport

UPMC Cancer Center at UPMC McKeesport

Sushil Beriwal
Ph: 412-647-2811

Meadowbrook

Charles A. & Betty Bott Cancer Center at Holy Redeemer Hospital

Pallav Mehta
Ph: 215-938-3551

Media

Riddle Memorial Hospital Cancer Center

Pramila Rani Anne
Ph: 215-955-6084

Monroeville

Intercommunity Cancer Center

David S. Parda
Ph: 877-284-2000

Moon Township

UPMC - Moon

Sushil Beriwal
Ph: 412-647-2811

Natrona Heights

Alle-Kiski Medical Center

David S. Parda
Ph: 877-284-2000

New Castle

Jameson Memorial Hospital - North Campus

Sushil Beriwal
Ph: 412-647-2811

Paoli

Cancer Center of Paoli Memorial Hospital

Albert S DeNittis
Ph: 866-225-5654

Philadelphia

Fox Chase Cancer Center - Philadelphia

Penny R Anderson
Ph: 215-728-4790

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia

Pramila Rani Anne
Ph: 215-955-6084

Pittsburgh

Allegheny Cancer Center at Allegheny General Hospital

David S. Parda
Ph: 877-284-2000

St. Clair Memorial Hospital Cancer Center

Sushil Beriwal
Ph: 412-647-2811

UPMC - Shadyside

Sushil Beriwal
Ph: 412-647-2811

UPMC Cancer Center at Magee-Womens Hospital

Sushil Beriwal
Ph: 412-647-2811

UPMC Cancer Center at UPMC Passavant

Sushil Beriwal
Ph: 412-647-2811

UPMC Cancer Center at UPMC St. Margaret

Sushil Beriwal
Ph: 412-647-2811

Reading

St. Joseph Medical Center

Leonard C Tuanquin
Ph: 610-378-2336
Email: danielward2@catholichealth.net

Sellersville

Grand View Hospital

Martin C Hightower
Ph: 215-453-4162
Email: PParsons@gvh.org

State College

Mount Nittany Medical Center

Jerome Derdel
Ph: 814-231-7813
Email: smoyer@mountnittany.org

Washington

Washington Hospital Cancer Center

Sushil Beriwal
Ph: 412-647-2811

West Reading

McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

Albert Yuen
Ph: 610-988-9323

Wynnewood

Lankenau Cancer Center at Lankenau Hospital

Albert S DeNittis
Ph: 866-225-5654

York

WellSpan Health

Amit B. Shah
Ph: 877-441-7957

South Carolina
Charleston

Hollings Cancer Center at Medical University of South Carolina

Jennifer L Harper
Ph: 843-792-9321

Greenville

Cancer Centers of the Carolinas - Faris Road

David L Grisell
Ph: 864-241-6251

CCOP - Greenville

David L Grisell
Ph: 864-241-6251

Greer

Cancer Centers of the Carolinas - Greer Radiation Oncology

David L Grisell
Ph: 864-241-6251

Gibbs Cancer Center-Pelham

Patricia C Griffin
Ph: 800-486-5941

Seneca

Cancer Centers of the Carolinas - Seneca

David L Grisell
Ph: 864-241-6251

Spartanburg

Cancer Centers of the Carolinas - Spartanburg

David L Grisell
Ph: 864-241-6251

Gibbs Regional Cancer Center at Spartanburg Regional Medical Center

Patricia C Griffin
Ph: 800-486-5941

West Columbia

Lexington Medical Center

Quillin G Davis
Ph: 803-936-8050

South Dakota
Rapid City

Rapid City Regional Hospital

Michael J Swartz
Ph: 605-716-3982
Email: research@rcrh.org

Sioux Falls

Avera Cancer Institute

James H Simon
Ph: 800-657-4377
Email: Jan.Healy@avera.org

Texas
Arlington

Texas Oncology, PA at Texas Cancer Center - Arlington South

Vivek S Kavadi
Ph: 281-277-5200

Austin

Texas Oncology - Midtown Austin

Vivek S Kavadi
Ph: 281-277-5200

Texas Oncology, PA at South Austin Cancer Center

Vivek S Kavadi
Ph: 281-277-5200

Bedford

Texas Oncology, PA at Harris Center HEB

Vivek S Kavadi
Ph: 281-277-5200

Dallas

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas

Asal S Rahimi
Ph: 214-648-7097

Denton

Texas Oncology, PA at Texas Cancer Center - Denton South

Vivek S Kavadi
Ph: 281-277-5200

Fort Worth

Klabzuba Cancer Center at Harris Methodist Fort Worth Hospital

Vivek S Kavadi
Ph: 281-277-5200

Houston

Memorial Hermann Hospital - Memorial City

Vivek S Kavadi
Ph: 281-277-5200

Irving

Baylor Medical Center at Irving

Barry N Wilcox
Ph: 800-422-9567

Plano

Texas Oncology - Plano West Cancer Center

Vivek S Kavadi
Ph: 281-277-5200

Round Rock

Texas Oncology, PA - Seton Williamson

Vivek S Kavadi
Ph: 281-277-5200

Texas Oncology, PA at Texas Cancer Center Round Rock

Vivek S Kavadi
Ph: 281-277-5200

San Antonio

University of Texas Health Science Center at San Antonio

Richard L Crownover
Ph: 210-567-0653
Email: che@uthscsa.edu

Sherman

Texas Oncology, PA at Texas Cancer Center - Sherman

Vivek S Kavadi
Ph: 281-277-5200

Sugar Land

Texas Oncology, PA at Texas Oncology Cancer Center Sugar Land

Vivek S Kavadi
Ph: 281-277-5200

Utah
Logan

Logan Regional Hospital

Vilija N Avizonis
Ph: 801-507-3950

Murray

Jon and Karen Huntsman Cancer Center at Intermountain Medical Center

Vilija N Avizonis
Ph: 801-507-3950

Ogden

Val and Ann Browning Cancer Center at McKay-Dee Hospital Center

Vilija N Avizonis
Ph: 801-507-3950

Saint George

Dixie Regional Medical Center - East Campus

Vilija N Avizonis
Ph: 801-507-3950

Salt Lake City

Huntsman Cancer Institute at University of Utah

Matthew M Poppe
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

Utah Cancer Specialists at UCS Cancer Center

Vilija N Avizonis
Ph: 801-507-3950

Vermont
Saint Johnsbury

Norris Cotton Cancer Center - North

Alan C. Hartford
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Virginia
Charlottesville

University of Virginia Cancer Center

Timothy N Showalter
Ph: 434-243-6143

Falls Church

Inova Fairfax Hospital

Samir P Kanani
Ph: 703-208-6650

Hampton

Sentara Cancer Institute at Sentara CarePlex Hospital

Scott S Williams
Ph: 757-388-2406

Norfolk

Sentara Cancer Institute at Sentara Norfolk General Hospital

Scott S Williams
Ph: 757-388-2406

Portsmouth

Naval Medical Center - Portsmouth

Edward F Miles
Ph: 757-953-5939

Richmond

Virginia Commonwealth University Massey Cancer Center

Harry D. Bear
Ph: 804-628-1939

Virginia Beach

Coastal Cancer Center at Sentara Virginia Beach General Hospital

Scott S Williams
Ph: 757-388-2406

Washington
Federal Way

St. Francis Hospital

Huong T. Pham
Ph: 800-354-9527

Mount Vernon

Skagit Valley Hospital Cancer Care Center

George E. Laramore
Ph: 206-616-8289

Seattle

CCOP - Virginia Mason Research Center

Huong T. Pham
Ph: 800-354-9527

Seattle Cancer Care Alliance

George E. Laramore
Ph: 206-616-8289

Sequim

Olympic Medical Cancer Center

George E. Laramore
Ph: 206-616-8289

Spokane

Cancer Care Northwest - North

Vivek S Kavadi
Ph: 281-277-5200

Cancer Care Northwest - Spokane South

Vivek S Kavadi
Ph: 281-277-5200

Wenatchee

Confluence Health - Wenatchee Valley Medical Center

George E. Laramore
Ph: 206-616-8289

West Virginia
Huntington

Edwards Comprehensive Cancer Center at Cabell Huntington Hospital

Maria-Rosalia B. Tria Tirona
Ph: 304-399-6617

Morgantown

Mary Babb Randolph Cancer Center at West Virginia University Hospitals

Geraldine M Jacobson
Ph: 304-293-2745
Email: sfilburn@hsc.wvu.edu

Wheeling

Schiffler Cancer Center at Wheeling Hospital

Jon David Pollock
Ph: 304-243-6442

Wisconsin
Antigo

Langlade Memorial Hospital

Darryl R. Barton
Ph: 877-405-6866

Appleton

Fox Valley Surgical Associates at Appleton Medical Center

Michael E Ray
Ph: 920-380-1500

Beloit

Beloit Memorial Hospital

Bethany M Anderson
Ph: 877-405-6866

Eau Claire

Luther Midlelfort Hospital

Larry R Past
Ph: 715-838-6072

Fond Du Lac

Central Wisconsin Cancer Program at Agnesian HealthCare

Timothy P Korytko
Ph: 800-494-2927

Green Bay

Bellin Memorial Hospital

Charlie C Pan
Ph: 800-865-1125

St. Mary's Hospital Medical Center - Green Bay

James L Leenstra
Ph: 920-433-8889

St. Vincent Hospital Regional Cancer Center

James L Leenstra
Ph: 920-433-8889

Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center

Mitchell H. Pincus
Ph: 800-252-2990

Johnson Creek

UW Cancer Center Johnson Creek

Bethany M Anderson
Ph: 877-405-6866

La Crosse

Franciscan Skemp Healthcare - La Crosse Campus

David J Schwartz
Ph: 608-392-9462
Email: MMCCOP@parknicollet.com

Gundersen Lutheran Center for Cancer and Blood

Collin D Driscoll
Ph: 608-775-2385
Email: cancerctr@gundluth.org

Madison

University of Wisconsin Paul P. Carbone Comprehensive Cancer Center

Bethany M Anderson
Ph: 877-405-6866

Marinette

Bay Area Cancer Care Center at Bay Area Medical Center

James L Leenstra
Ph: 920-433-8889

Menomonee Falls

Community Memorial Hospital Cancer Care Center

Adam D Currey
Ph: 414-805-4380

Mequon

Columbia Saint Mary's Hospital - Ozaukee

Erika L Swanson
Ph: 414-326-2675
Email: clinicaltrials@columbia-stmarys.org

Milwaukee

Columbia-Saint Mary's Cancer Care Center

Erika L Swanson
Ph: 414-326-2675
Email: clinicaltrials@columbia-stmarys.org

Froedtert Hospital and Medical College of Wisconsin

Adam D Currey
Ph: 414-805-4380

Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center

Mitchell H. Pincus
Ph: 800-252-2990

Racine

All Saints Cancer Center at Wheaton Franciscan Healthcare

James H. Taylor
Ph: 414-874-4541
Email: Kelli.holton@wfhc.org

Sheboygan

Vince Lombardi Cancer Clinic - Sheboygan

Mitchell H. Pincus
Ph: 800-252-2990

Sturgeon Bay

Door County Cancer Center at Door County Memorial Hospital

James L Leenstra
Ph: 920-433-8889

Summit

Aurora Medical Center

Mitchell H. Pincus
Ph: 800-252-2990

Two Rivers

Vince Lombardi Cancer Clinic - Two Rivers

Mitchell H. Pincus
Ph: 800-252-2990

Waukesha

Waukesha Memorial Hospital Regional Cancer Center

Wingate F. Clapper
Ph: 262-928-7632

Wausau

University of Wisconcin Cancer Center at Aspirus Wausau Hospital

Darryl R. Barton
Ph: 877-405-6866

West Allis

Aurora Women's Pavilion of West Allis Memorial Hospital

Mitchell H. Pincus
Ph: 800-252-2990

Canada

Alberta
Edmonton

Cross Cancer Institute at University of Alberta

Zsolt Gabos
Ph: 780-432-8500

British Columbia
Vancouver

British Columbia Cancer Agency - Vancouver Cancer Centre

Lorna M Weir
Ph: 888-939-3333

Manitoba
Winnipeg

CancerCare Manitoba

Maged Nashed
Ph: 866-561-1026
Email: CIO_Web@cancercare.mb.ca

New Brunswick
Saint John

Saint John Regional Hospital

Farah Naz
Ph: 506-648-6890

Ontario
Kitchener

Grand River Regional Cancer Centre at Grand River Hospital

Darindra D Gopaul
Ph: 519-749-4300ext2307

London

London Regional Cancer Program at London Health Sciences Centre

Tracy L Sexton
Ph: 519-685-8600

Ottawa

Irving Greenberg Family Cancer Centre at Queensway-Carleton Hospital

Samy El-Sayed
Ph: 613-761-4395
Email: info@ohri.ca

Ottawa Hospital Regional Cancer Centre - General Campus

Samy El-Sayed
Ph: 613-761-4395
Email: info@ohri.ca

Windsor

Windsor Regional Cancer Centre at Windsor Regional Hospital

Khalid J Hirmiz
Ph: 519-253-5253

Quebec
Laval

Cite de la Sante de Laval

Sebastien Clavel
Ph: 450-975-5359
Email: sylvie.beaudoin.chum@ssss.gouv.qc.ca

Montreal

Hopital Notre-Dame du CHUM

Sophie Lavertu
Ph: 514-890-8000ext23611
Email: sylvie.beaudoin.chum@ssss.gouv.qc.ca

Maisonneuve-Rosemont Hospital

Michael Yassa
Ph: 514-252-3400ext3329

McGill Cancer Centre at McGill University

Tarek Hijal
Ph: 514-934-1934ext42953
Email: evelyn.ortega@muhc.mcgill.ca

Sherbrooke

CHUS-Hopital Fleurimont

Sawyna Provencher
Ph: 819-820-6480
Email: crcinformation.chus@ssss.gouv.qc.ca

Saskatchewan
Regina

Allan Blair Cancer Centre at Pasqua Hospital

Asim Amjad
Ph: 306-766-2213

Hong Kong

Chai Wan

Pamela Youde Nethersole Eastern Hospital

Foon-Yiu Cheung
Ph: 888-823-5923
Email: ctsucontact@westat.com

Israel

Petach Tikva

Rabin Medical Center - Beilinson Campus

Aaron M Allen
Ph: (866) 790-4500

Tel Hashomer

Chaim Sheba Medical Center

Merav Akiva Ben-David
Ph: 972 3 530-5943

Republic of Korea

Seoul

Severance Hospital

Yong Bae Kim
Ph: 215-574-3173

Gyeonggi-do
Goyang-si

National Cancer Center - Korea

Kwan H Cho
Ph: 888-823-5923
Email: ctsucontact@westat.com

Republic of Singapore

Singapore

Cancer Institute at National University Hospital

Ihsiung J Tang
Ph: 215-574-3173

Switzerland

Aarau

Kantonsspital Aarau

Stephan B Bodis
Ph: 215-574-3173

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT01349322
ClinicalTrials.gov processed this data on November 12, 2014

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.