Radiotherapy for Malignant Astrocytomas in the Elderly

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Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentCompleted70 and overOtherPHRC, P000502 AOM 98071

Trial Description


A randomized trial comparing radiotherapy with supportive care in patients aged 70 years or older with newly diagnosed, histologically confirmed anaplastic astrocytoma or glioblastoma, and a Karnofsky performance status > 70.

Eligibility Criteria

Inclusion Criteria:

  • Glioblastoma and anaplastic astrocytoma, supratentorial, histologically confirmed
  • Brain CT scan or MRI within 28 days before surgery
  • Age: 70 years or older
  • Karnofsky performance status, 70 or more.
  • Life expectancy over 12 weeks
  • Informed consent

Exclusion Criteria:

  • Brain radiotherapy
  • Chemotherapy
  • Severe systemic disease

Trial Contact Information

Trial Lead Organizations/Sponsors

Assistance Publique Hopitaux de Paris

    jean-yves Delattre, MD, Principal Investigator
    Florence Keime-Guibert, MD, Principal Investigator

    Link to the current record.
    NLM Identifier NCT00430911 processed this data on January 29, 2015

    Note: Information about this trial is from the database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the record to standardize the names of study sponsors, sites, and contacts. only lists sites that are recruiting patients for active trials, whereas lists all sites for all trials. Questions and comments regarding the presented information should be directed to