Three Different Radiation Therapy Regimens in Treating Patients With Limited-Stage Small Cell Lung Cancer Receiving Cisplatin and Etoposide

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Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentActive18 and overNCI, OtherCDR0000588879
CALGB-30610, RTOG 0538, U10CA031946, NCT00632853

Trial Description

Summary

Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as etoposide and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known which radiation therapy regimen is more effective when given together with chemotherapy in treating patients with limited-stage small cell lung cancer. This randomized phase III trial is comparing different chest radiation therapy regimens to see how well they work in treating patients with limited-stage small cell lung cancer.

Further Study Information

OBJECTIVES:

Primary

  • To determine whether administering high-dose thoracic radiotherapy, 70 Gy (2 Gy once daily over 7 weeks) or 61.2 Gy (1.8 Gy once daily for 16 days followed by 1.8 Gy twice daily for 9 days), will improve median and 2-year survival compared with 45 Gy (1.5 Gy twice daily over 3 weeks) in patients with limited-stage small cell lung cancer.

Secondary

  • To compare treatment-related toxic effects of thoracic radiotherapy regimens in patients with limited-stage small cell lung cancer.
  • To compare response rates, failure-free survival, and toxicity of thoracic radiotherapy regimens in patients with limited-stage small cell lung cancer.
  • To compare rates of local relapse, distant metastases, and brain metastases with these regimens.
  • To describe the patterns of use of thoracic intensity-modulated radiotherapy (IMRT) in patients with limited-stage small cell lung cancer.

OUTLINE: This is a 2-part, multicenter, randomized study. Patients are stratified according to gender, weight loss 6 months prior to study entry (≤ 5% of body weight vs > 5% of body weight), ECOG performance status (0 vs 1 vs 2), radiotherapy technique (intensity-modulated radiotherapy vs 3-dimensional conformal radiotherapy), and radiotherapy start time (at first course of protocol chemotherapy, after one course of prior non-protocol chemotherapy vs at first course of protocol chemotherapy, without prior non-protocol chemotherapy vs at second course of protocol chemotherapy, without prior non-protocol chemotherapy).

  • Part 1: Patients are randomized to 1 of 3 treatment arms.
  • Arm I: Patients undergo standard-dose (45 Gy given in 30 treatments) thoracic radiotherapy twice daily, 5 days a week, for 3 weeks. Patients also receive cisplatin IV on day 1 and etoposide IV on days 1, 2, and 3.
  • Arm II: Patients undergo higher-dose (70 Gy given in 35 treatments) thoracic radiotherapy once daily, 5 days a week, for 7 weeks. Patients also receive cisplatin and etoposide as in arm I.
  • Arm III: (discontinued as of 03/10/13) Patients undergo higher-dose (61.2 Gy given in 34 treatments) thoracic radiotherapy once daily, 5 days a week, during the initial 16 days (approximately 3 weeks) of treatment and then twice daily, 5 days a week, for the final 9 days (approximately 2 weeks) of treatment. Patients also receive cisplatin and etoposide as in arm I.

In all arms, treatment with cisplatin and etoposide repeats every 21 days for 4 courses in the absence of disease progression or unacceptable toxicity.

  • Part 2: An interim analysis was conducted after accrual of 30 patients per arm and one experimental arm based upon a comparison of treatment-related toxicity was selected. The most toxic experimental arm was discontinued, and the trial continues comparing standard therapy (arm I) to the selected experimental regimen (arm II) as described in part 1.

Prophylactic radiotherapy: Within 3-6 weeks after completion of chemotherapy, patients with responding disease are eligible to undergo prophylactic radiotherapy to the brain once a day, 5 days a week, for 2 weeks.

After completion of study treatment, patients are followed up at least every 3 months for 2 years, every 6 months for 3 years, and then annually for 5 years or until disease progression. At disease progression, patients are followed up every 6 months.

Eligibility Criteria

DISEASE CHARACTERISTICS:

  • Histologically or cytologically documented small cell lung cancer (SCLC)
  • Limited-stage disease
  • Disease restricted to one hemithorax with regional lymph node metastases, including ipsilateral hilar, ipsilateral and contralateral mediastinal, and ipsilateral supraclavicular lymph nodes
  • The following patients are not eligible:
  • Patients with disease involvement of the contralateral hilar or supraclavicular lymph nodes
  • Patients with pleural effusions that are visible on plain chest radiographs, whether cytologically positive or not
  • Patients with cytologically positive pleural or pericardial fluid, regardless of the appearance on plain x-ray
  • Measurable disease, defined as at least one unidimensionally measurable lesion ≥ 2 cm by conventional techniques OR ≥ 1 cm by spiral CT scan

PATIENT CHARACTERISTICS:

  • Eastern Cooperative Oncology Group (ECOG) performance status 0-2
  • Granulocytes ≥ 1,500/µl
  • Platelet count ≥ 100,000/µl
  • Total bilirubin ≤ 1.5 times upper limit of normal (ULN)
  • AST ≤ 2.0 times ULN
  • Serum creatinine ≤ 1.5 times ULN OR creatinine clearance ≥ 70 mL/min
  • Not pregnant or nursing
  • Negative pregnancy test
  • Fertile patients must use effective contraception

PRIOR CONCURRENT THERAPY:

  • Patients may have received one and only one course of chemotherapy prior to enrolling on CALGB 30610, which must have included cisplatin and etoposide
  • If a patient has had one course of cisplatin/etoposide prior to registration, the patient must have had all of the prior-to-registration tests prior to starting their first course of chemotherapy
  • Registration to CALGB-30610 must take place within 14-21 days after the start of the non-protocol therapy; failing to do all of the above will make the patient NOT eligible for CALGB-30610
  • No prior radiotherapy or chemotherapy (except for the chemotherapy described above) for SCLC
  • No prior mediastinal or thoracic radiotherapy
  • No prior complete surgical resection of SCLC

Trial Contact Information

Trial Lead Organizations/Sponsors

Cancer and Leukemia Group B

  • National Cancer Institute
  • Radiation Therapy Oncology Group
  • Eastern Cooperative Oncology Group
  • North Central Cancer Treatment Group
  • Southwest Oncology Group
Jeffrey A. Bogart, Study Chair
Gregory A. Masters, Study Chair
Ritsuko U. Komaki, Study Chair
John Heymach, Study Chair

Trial Sites

U.S.A.

Alabama
Birmingham

Kirklin Clinic at Acton Road

Michael C Dobelbower
Ph: 205-934-0309

UAB Comprehensive Cancer Center

Michael C Dobelbower
Ph: 205-934-0309

Alaska
Anchorage

Alaska Breast Care and Surgery LLC

Keith S. Lanier
Ph: 503-215-6412

Alaska Women's Cancer Care

Keith S. Lanier
Ph: 503-215-6412

Anchorage Oncology Centre

Keith S. Lanier
Ph: 503-215-6412

Katmai Oncology Group

Keith S. Lanier
Ph: 503-215-6412

Providence Cancer Center

Keith S. Lanier
Ph: 503-215-6412

Arkansas
Jonesboro

NEA Medical Clinic - East Matthews

Carroll Dean Scroggin
Ph: 870-972-7235

Little Rock

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences

Rangaswamy Govindarajan
Ph: 501-686-8274

California
Auburn

Auburn Radiation Oncology

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Berkeley

Alta Bates Summit Comprehensive Cancer Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Burbank

Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center

Keith S. Lanier
Ph: 503-215-6412

Burlingame

Peninsula Medical Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Cameron Park

Radiation Oncology Centers - Cameron Park

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Emeryville

Bay Area Breast Surgeons, Incorporated

James H. Feusner
Ph: 510-450-7600

Epic Care - Oakland

James H. Feusner
Ph: 510-450-7600

Fresno

California Cancer Center - Woodward Park Office

Uma G Swamy
Ph: 559-447-4050

University Oncology Associates

Uma G Swamy
Ph: 559-447-4050

Greenbrae

Marin Cancer Institute at Marin General Hospital

Peter D. Eisenberg
Ph: 415-925-5000
Email: info@marinspecialtycare.com

Peter D. Eisenberg
Ph: 415-925-5000
Email: info@marinspecialtycare.com

Martinez

Contra Costa Regional Medical Center

James H. Feusner
Ph: 510-450-7600

Modesto

Memorial Medical Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Mountain View

Palo Alto Medical Foundation

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Novato

Sutter Health Western Division Cancer Research Group

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Oakland

Alta Bates Summit Medical Center - Summit Campus

James H. Feusner
Ph: 510-450-7600

CCOP - Bay Area Tumor Institute

James H. Feusner
Ph: 510-450-7600

Kaiser Permanente-Oakland

Louis Fehrenbacher
Ph: 626-564-3455

Larry G Strieff MD Medical Corporation

James H. Feusner
Ph: 510-450-7600

Palo Alto

Palo Alto Medical Foundation - Palo Alto

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stanford Cancer Center

Billy W Loo
Ph: 650-498-7061
Email: ccto-office@stanford.edu

Redwood City

Kaiser Permanente Medical Center - Redwood City

Louis Fehrenbacher
Ph: 626-564-3455

Richmond

Kaiser Permanente Medical Center - Richmond

Louis Fehrenbacher
Ph: 626-564-3455

Roseville

Kaiser Permanente Medical Center - Roseville

Louis Fehrenbacher
Ph: 626-564-3455

Radiation Oncology Center - Roseville

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Sutter Cancer Center at Roseville Medical Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Sacramento

Kaiser Permanente Medical Center - Sacramento

Louis Fehrenbacher
Ph: 626-564-3455

South Sacramento Kaiser-Permanente Medical Center

Louis Fehrenbacher
Ph: 626-564-3455

Sutter Cancer Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

University of California Davis Cancer Center

David R. Gandara
Ph: 916-734-3089

Saint Helena

Saint Helena Hospital

Gregory B Smith
Ph: 707-967-3698

San Francisco

California Pacific Medical Center - California Campus

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Kaiser Permanente Medical Center - San Francisco Geary Campus

Louis Fehrenbacher
Ph: 626-564-3455

San Jose

Kaiser Permanente Medical Center - Santa Teresa

Louis Fehrenbacher
Ph: 626-564-3455

San Leandro

Kaiser Permanente Medical Center - Hayward

Louis Fehrenbacher
Ph: 626-564-3455

San Rafael

Kaiser Foundation Hospital - San Rafael

Louis Fehrenbacher
Ph: 626-564-3455

Santa Clara

Kaiser Permanente Medical Center - Santa Clara Homestead Campus

Louis Fehrenbacher
Ph: 626-564-3455

Louis Fehrenbacher
Ph: 626-564-3455

Santa Cruz

Palo Alto Medical Foundation-Santa Cruz

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Santa Rosa

Kaiser Permanente Medical Center - Santa Rosa

Louis Fehrenbacher
Ph: 626-564-3455

South San Francisco

Kaiser Permanente Medical Center - South San Francisco

Louis Fehrenbacher
Ph: 626-564-3455

Stockton

Kaiser Permanente Medical Facility - Stockton

Louis Fehrenbacher
Ph: 626-564-3455

Sunnyvale

Palo Atlo Medical Foundation-Sunnyvale

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Vacaville

Kaiser Permanente Medical Center - Vacaville

Louis Fehrenbacher
Ph: 626-564-3455

Solano Radiation Oncology Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Vallejo

Kaiser Permanente Medical Center - Vallejo

Louis Fehrenbacher
Ph: 626-564-3455

Sutter Solano Medical Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Walnut Creek

Kaiser Permanente Medical Center - Walnut Creek

Louis Fehrenbacher
Ph: 626-564-3455

Colorado
Aurora

Medical Center of Aurora - South Campus

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Aurora

Keren Sturtz
Ph: 888-785-6789

Boulder

Boulder Community Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers-Boulder

Keren Sturtz
Ph: 888-785-6789

Colorado Springs

Penrose Cancer Center at Penrose Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers at the Pavilion

Keren Sturtz
Ph: 888-785-6789

Denver

CCOP - Colorado Cancer Research Program

Keren Sturtz
Ph: 888-785-6789

Colorado Blood Cancer Institute

Keren Sturtz
Ph: 888-785-6789

Porter Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Presbyterian - St. Luke's Medical Center

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Denver Midtown

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers-Rose

Keren Sturtz
Ph: 888-785-6789

Rose Medical Center

Keren Sturtz
Ph: 888-785-6789

St. Joseph Hospital

Keren Sturtz
Ph: 888-785-6789

University of Colorado Cancer Center at UC Health Sciences Center

Jeffrey A. Bogart
Email: bogartj@upstate.edu

Durango

Mercy Medical Center

Keren Sturtz
Ph: 888-785-6789

Southwest Oncology, PC

Keren Sturtz
Ph: 888-785-6789

Englewood

Comprehensive Cancer Care and Research Institute of Colorado LLC

Keren Sturtz
Ph: 888-785-6789

Swedish Medical Center

Keren Sturtz
Ph: 888-785-6789

Golden

Mountain Blue Cancer Care Center

Keren Sturtz
Ph: 888-785-6789

Greeley

North Colorado Medical Center

Keren Sturtz
Ph: 888-785-6789

Greenwood Village

Breast Cancer Care Consultants

Keren Sturtz
Ph: 888-785-6789

Lakewood

Rocky Mountain Cancer Centers-Lakewood

Keren Sturtz
Ph: 888-785-6789

St. Anthony Central Hospital

Keren Sturtz
Ph: 888-785-6789

Littleton

Littleton Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Littleton

Keren Sturtz
Ph: 888-785-6789

Lone Tree

Rocky Mountain Cancer Centers - Lone Tree

Keren Sturtz
Ph: 888-785-6789

Sky Ridge Medical Center

Keren Sturtz
Ph: 888-785-6789

Longmont

Hope Cancer Care Center at Longmont United Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Longmont

Keren Sturtz
Ph: 888-785-6789

Loveland

McKee Medical Center

Keren Sturtz
Ph: 888-785-6789

Parker

Parker Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Parker

Keren Sturtz
Ph: 888-785-6789

Pueblo

Rocky Mountain Cancer Centers - Pueblo

Keren Sturtz
Ph: 888-785-6789

St. Mary - Corwin Regional Medical Center

Keren Sturtz
Ph: 888-785-6789

Thornton

Rocky Mountain Cancer Centers - Thornton

Keren Sturtz
Ph: 888-785-6789

Wheat Ridge

Exempla Lutheran Medical Center

Keren Sturtz
Ph: 888-785-6789

Connecticut
Hartford

Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

Samir Narayan
Ph: 734-712-4673

Delaware
Lewes

Tunnell Cancer Center at Beebe Medical Center

Stephen Scott Grubbs
Ph: 302-733-6227

Newark

Christiana Gynecologic Oncology, LLC

Stephen Scott Grubbs
Ph: 302-733-6227

Delaware Clinical and Laboratory Physicians

Stephen Scott Grubbs
Ph: 302-733-6227

Helen F. Graham Cancer Center at Christiana Hospital

Stephen Scott Grubbs
Ph: 302-733-6227

Stephen Scott Grubbs
Ph: 302-733-6227

Medical Oncology Hematology Consultants, PA at Helen F. Graham Cancer Center

Stephen Scott Grubbs
Ph: 302-733-6227

Regional Hematology/Oncology, PA - Newark

Stephen Scott Grubbs
Ph: 302-733-6227

Rehoboth Beach

Beebe Health Campus

Stephen Scott Grubbs
Ph: 302-733-6227

Seaford

Nanticoke Memorial Hospital

Stephen Scott Grubbs
Ph: 302-733-6227

Wilmington

Christiana Care Health System-Wilmington Hospital

Stephen Scott Grubbs
Ph: 302-733-6227

Florida
Jacksonville

Baptist Cancer Institute - Jacksonville

Mark E Augspurger
Ph: 904-202-7051

Integrated Community Oncology Network - Baptist South

Mark E Augspurger
Ph: 904-202-7051

Miami Beach

CCOP - Mount Sinai Medical Center

Michael Schwartz
Ph: 305-674-2625
Email: info@msccop.com

Orange Park

Integrated Community Oncology Network - Orange Park

Mark E Augspurger
Ph: 904-202-7051

Palatka

Cancer Specialists of North Florida-Putnam

Mark E Augspurger
Ph: 904-202-7051

Saint Augustine

Integrated Community Oncology Network at St. Augustine Cancer Center

Mark E Augspurger
Ph: 904-202-7051

Georgia
Atlanta

Emory University Hospital Midtown

Jeffrey A. Bogart
Ph: 315-464-5276
Email: bogartj@upstate.edu

Winship Cancer Institute of Emory University

Kristin A Higgins
Ph: 404-778-1868

Columbus

John B. Amos Cancer Center

Douglas F. Ciuba
Ph: 706-660-6404

Gainesville

Northeast Georgia Medical Center

Richard J. LoCicero
Ph: 770-219-8800
Email: cancerpatient.navigator@nghs.com

Savannah

Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center

Harvey C. Lebos
Ph: 912-350-8568

Low Country Cancer Care Associates, PC

Harvey C. Lebos
Ph: 912-350-8568

Summit Cancer Care-Memorial

Harvey C. Lebos
Ph: 912-350-8568

Hawaii
Honolulu

Kaiser Permanente - Moanalua Medical Center and Clinic

Louis Fehrenbacher
Ph: 626-564-3455

Idaho
Boise

Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

Samir Narayan
Ph: 734-712-4673

Coeur D'Alene

Kootenai Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Post Falls

Kootenai Cancer Center - Post Falls

Benjamin Thomas Marchello
Ph: 800-648-6274

Sandpoint

Kootenai Cancer

Benjamin Thomas Marchello
Ph: 800-648-6274

Illinois
Bloomington

Illinois CancerCare - Bloomington

Nguyet A Le-Lindqwister
Ph: 800-793-2262

St. Joseph Medical Center

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Canton

Illinois CancerCare - Canton

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Carbondale

Memorial Hospital of Carbondale

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Carthage

Illinois CancerCare - Carthage

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Centralia

Centralia Oncology Clinic

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Chicago

Creticos Cancer Center at Advocate Illinois Masonic Medical Center

Deepti A. Singh
Ph: 773-296-5360

John H. Stroger, Jr. Hospital of Cook County

Thomas E. Lad
Ph: 312-864-6000

Swedish Covenant Hospital

Elyse A Lambiase
Ph: 847-316-6994

University of Chicago Cancer Research Center

Ravi Salgia
Ph: 773-834-7424

Decatur

Cancer Care Center of Decatur

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Decatur Memorial Hospital Cancer Care Institute

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Effingham

Crossroads Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Eureka

Illinois CancerCare - Eureka

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Evanston

St. Francis Hospital

Elyse A Lambiase
Ph: 847-316-6994

Galesburg

Galesburg Clinic, PC

Nguyet A Le-Lindqwister
Ph: 800-793-2262

InterCommunity Cancer Center of Western Illinois

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Medical and Surgical Specialists, LLC

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Kewanee

Illinois CancerCare - Kewanee Clinic

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Macomb

Illinois CancerCare - Macomb

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Moline

Garneau, Stewart C MD (UIA Investigator)

David M Spector
Ph: 309-779-4200

Spector, David MD (UIA Investigator)

David M Spector
Ph: 309-779-4200

Trinity Cancer Center at Trinity Medical Center - 7th Street Campus

David M Spector
Ph: 309-779-4200

Oak Lawn

Advocate Christ Medical Center

Faisal S Vali
Ph: 800-323-8622

Ottawa

Illinois CancerCare - Ottawa

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Radiation Oncology of Northern Illinois

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Pekin

Cancer Treatment Center at Pekin Hospital

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Illinois CancerCare - Pekin

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Peoria

Illinois CancerCare - Peoria

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Methodist Medical Center of Illinois

Nguyet A Le-Lindqwister
Ph: 800-793-2262

OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC

Nguyet A Le-Lindqwister
Ph: 800-793-2262

OSF St. Francis Medical Center

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Peru

Illinois CancerCare - Princeton

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Valley Cancer Center

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Princeton

Illinois CancerCare - Princeton

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Rockford

Advanced Care and Treatment Medical Group, PC

Harvey Eric Einhorn
Ph: 779-696-9400
Email: cancercare@swedishamerican.org

Center for Cancer Care at OSF Saint Anthony Medical Center

Shylendra B Sreenivasappa
Ph: 815-227-2633

Springfield

Central Illinois Hematology Oncology Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Regional Cancer Center at Memorial Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Simmons Cooper Cancer Institute

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Springfield Clinic - Main Campus

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Swansea

Cancer Care Specialists of Illinois-Swansea

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Indiana
Elkhart

Michiana Hematology-Oncology, PC - Elkhart

Rafat H. Ansari
Ph: 574-234-5123

Fort Wayne

Parkview Regional Cancer Center at Parkview Health

Brian K Chang
Ph: 260-373-8888
Email: parkviewresearch@parkview.com

Radiation Oncology Associates Southwest

Brian K Chang
Ph: 260-373-8888
Email: parkviewresearch@parkview.com

Indianapolis

Central Indiana Cancer Centers - East

Hillary H Wu
Ph: 317-356-2422

St. Vincent Oncology Center

Robert H Liebross
Ph: 317-338-2194

Mishawaka

Memorial Regional Cancer Center Day Road

Thomas Joseph Reid
Ph: 800-284-7370

Michiana Hematology-Oncology, PC - Mishawaka

Rafat H. Ansari
Ph: 574-234-5123

Saint Joseph's Medical Center

Rafat H. Ansari
Ph: 574-234-5123

Muncie

Cancer Center at Ball Memorial Hospital

Yunjie X Lin
Ph: 765-751-5850

Plymouth

Michiana Hematology Oncology PC - Plymouth

Rafat H. Ansari
Ph: 574-234-5123

South Bend

CCOP - Northern Indiana CR Consortium

Rafat H. Ansari
Ph: 574-234-5123

Memorial Hospital of South Bend

Thomas Joseph Reid
Ph: 800-284-7370

Michiana Hematology-Oncology, PC - South Bend

Rafat H. Ansari
Ph: 574-234-5123

Westville

Michiana Hematology Oncology-PC Westville

Rafat H. Ansari
Ph: 574-234-5123

Iowa
Bettendorf

Constantinou, Costas L MD (UIA Investigator)

David M Spector
Ph: 309-779-4200

Clive

Medical Oncology and Hematology Associates-West Des Moines

Mehmet S. Copur
Ph: 800-998-2119

Mercy Cancer Center - West Lakes

Mehmet S. Copur
Ph: 800-998-2119

Des Moines

Medical Oncology and Hematology Associates at Mercy Cancer Center

Mehmet S. Copur
Ph: 800-998-2119

Mercy Cancer Center at Mercy Medical Center - Des Moines

Mehmet S. Copur
Ph: 800-998-2119

West Des Moines

Methodist West Hospital

Mehmet S. Copur
Ph: 800-998-2119

Kansas
Chanute

Cancer Center of Kansas, PA - Chanute

Shaker R. Dakhil
Ph: 316-262-4467

Dodge City

Cancer Center of Kansas, PA - Dodge City

Shaker R. Dakhil
Ph: 316-262-4467

El Dorado

Cancer Center of Kansas, PA - El Dorado

Shaker R. Dakhil
Ph: 316-262-4467

Fort Scott

Cancer Center of Kansas - Fort Scott

Shaker R. Dakhil
Ph: 316-262-4467

Independence

Cancer Center of Kansas-Independence

Shaker R. Dakhil
Ph: 316-262-4467

Kingman

Cancer Center of Kansas, PA - Kingman

Shaker R. Dakhil
Ph: 316-262-4467

Lawrence

Lawrence Memorial Hospital

Shaker R. Dakhil
Ph: 316-262-4467

Liberal

Cancer Center of Kansas, PA - Liberal

Shaker R. Dakhil
Ph: 316-262-4467

Newton

Cancer Center of Kansas, PA - Newton

Shaker R. Dakhil
Ph: 316-262-4467

Overland Park

Menorah Medical Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Saint Luke's Hospital - South

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Parsons

Cancer Center of Kansas, PA - Parsons

Shaker R. Dakhil
Ph: 316-262-4467

Pratt

Cancer Center of Kansas, PA - Pratt

Shaker R. Dakhil
Ph: 316-262-4467

Salina

Cancer Center of Kansas, PA - Salina

Shaker R. Dakhil
Ph: 316-262-4467

Topeka

Cotton-O'Neil Cancer Center

David E Einspahr
Ph: 785-270-4963

Wellington

Cancer Center of Kansas, PA - Wellington

Shaker R. Dakhil
Ph: 316-262-4467

Wichita

Associates in Women's Health, PA - North Hillside

Shaker R. Dakhil
Ph: 316-262-4467

Cancer Center of Kansas, PA - Medical Arts Tower

Shaker R. Dakhil
Ph: 316-262-4467

Cancer Center of Kansas, PA - Wichita

Shaker R. Dakhil
Ph: 316-262-4467

Via Christi Cancer Center at Via Christi Regional Medical Center

Shaker R. Dakhil
Ph: 316-262-4467

Wesley Medical Center

Shaker R. Dakhil
Ph: 316-262-4467

Winfield

Cancer Center of Kansas, PA - Winfield

Shaker R. Dakhil
Ph: 316-262-4467

Kentucky
Lexington

Saint Joseph East

Mehmet S. Copur
Ph: 800-998-2119

United Radiation Oncology - Bob-O-Link Drive Office

Mehmet S. Copur
Ph: 800-998-2119

University of Kentucky Chandler Medical Center

Ronald McGarry
Ph: 859-257-3379

Louisville

Jewish Hospital

Mehmet S. Copur
Ph: 800-998-2119

Jewish Hospital Medical Center Northeast

Mehmet S. Copur
Ph: 800-998-2119

University of Louisville School of Medicine

Neal E Dunlap
Ph: 866-530-5516

Louisiana
Baton Rouge

Mary Bird Perkins Cancer Center - Baton Rouge

Augusto C Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

Pennington Cancer Center at Baton Rouge General

William R. Robinson
Ph: 504-988-6121

New Orleans

Medical Center of Louisiana - New Orleans

Augusto C Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

Ochsner Cancer Institute at Ochsner Clinic Foundation

Suma P Satti
Ph: 888-562-4763

Stanley S. Scott Cancer Center at Louisiana State University Medical Center - New Orleans

Augusto C Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

Tulane Cancer Center at Tulane University Hospital and Clinic

William R. Robinson
Ph: 504-988-6121

Maine
Lewiston

Central Maine Comprehensive Cancer Center at Central Maine Medical Center

Courtney A Jensen
Ph: 207-795-8250
Email: benderli@cmhc.org

Maryland
Baltimore

Alvin and Lois Lapidus Cancer Institute at Sinai Hospital

Roberto F Martinez
Ph: 410-601-6120
Email: pridgely@lifebridgehealth.org

Greater Baltimore Medical Center Cancer Center

Robert K. Brookland
Ph: 443-849-3706

Greenebaum Cancer Center at University of Maryland Medical Center

Josephine L Feliciano
Ph: 800-888-8823

St. Agnes Hospital Cancer Center

Richard S. Hudes
Ph: 410-368-2910

Bethesda

National Naval Medical Center

Corey A Carter
Ph: 800-411-1222

Easton

Shore Regional Cancer Center at Memorial Hospital - Easton

John Philip Mastandrea
Ph: 410-820-6800ext108
Email: srichter@shorehealth.org

Randallstown

Northwest Hospital Center

Roberto F Martinez
Ph: 410-601-6120
Email: pridgely@lifebridgehealth.org

Rockville

Unidentified Site

Jeffrey A. Bogart
Ph: 315-464-5276
Email: bogartj@upstate.edu

Salisbury

Peninsula Regional Medical Center

Paul E Zorsky
Ph: 410-543-7017
Email: sandra.heineken@peninsula.org

Massachusetts
Boston

Dana-Farber/Brigham and Women's Cancer Center

David E Kozono
Ph: 866-790-4500

Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute

David E Kozono
Ph: 866-790-4500

Massachusetts General Hospital

David E Kozono
Ph: 866-790-4500

Worcester

UMASS Memorial Cancer Center - University Campus

Vijay K Kasturi
Ph: 508-856-3216
Email: cancer.research@umassmed.edu

Michigan
Ann Arbor

Saint Joseph Mercy Cancer Center

Samir Narayan
Ph: 734-712-4673

University of Michigan Comprehensive Cancer Center

Jeffrey A. Bogart
Email: bogartj@upstate.edu

Dearborn

Oakwood Cancer Center at Oakwood Hospital and Medical Center

Samir Narayan
Ph: 734-712-4673

Detroit

Van Elslander Cancer Center at St. John Hospital and Medical Center

Samir Narayan
Ph: 734-712-4673

Escanaba

Green Bay Oncology, Limited - Escanaba

Anthony J. Jaslowski
Ph: 800-432-6049

Flint

Genesys Hurley Cancer Institute

Samir Narayan
Ph: 734-712-4673

Hurley Medical Center

Samir Narayan
Ph: 734-712-4673

Iron Mountain

Green Bay Oncology - Iron Mountain

Anthony J. Jaslowski
Ph: 800-432-6049

Jackson

Gayle M. Jacob Cancer Center at Allegiance Health

Samir Narayan
Ph: 734-712-4673

Kalamazoo

West Michigan Cancer Center

Sunil Nagpal
Ph: 269-373-7458

Lansing

Sparrow Regional Cancer Center

Samir Narayan
Ph: 734-712-4673

Livonia

St. Mary Mercy Hospital

Samir Narayan
Ph: 734-712-4673

Niles

Lakeland Hospital - Niles

Rafat H. Ansari
Ph: 574-234-5123

Pontiac

St. Joseph Mercy Oakland

Samir Narayan
Ph: 734-712-4673

Port Huron

Mercy Regional Cancer Center at Mercy Hospital

Samir Narayan
Ph: 734-712-4673

Royal Oak

William Beaumont Hospital - Royal Oak Campus

John M. Robertson
Ph: 248-551-7695

Saginaw

Seton Cancer Institute at Saint Mary's - Saginaw

Samir Narayan
Ph: 734-712-4673

Southfield

Providence Hospital - Southfield

Anibal Drelichman
Ph: 248-849-5337
Email: jaswinder.grewal@stjohn.org

St. Joseph

Lakeland Regional Cancer Care Center - St. Joseph

Rafat H. Ansari
Ph: 574-234-5123

Troy

William Beaumont Hospital - Troy Campus

John M. Robertson
Ph: 248-551-7695

Warren

St. John Macomb Hospital

Samir Narayan
Ph: 734-712-4673

Minnesota
Bemidji

MeritCare Bemidji

Preston D. Steen
Ph: 701-234-6161

Burnsville

Fairview Ridges Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Coon Rapids

Mercy and Unity Cancer Center at Mercy Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Edina

Fairview Southdale Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Fridley

Mercy and Unity Cancer Center at Unity Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Hutchinson

Hutchinson Area Health Care

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Maplewood

HealthEast Cancer Care at St. John's Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Minnesota Oncology - Maplewood

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Minneapolis

Health Partners Inc

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Hennepin County Medical Center - Minneapolis

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Virginia Piper Cancer Institute at Abbott - Northwestern Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

New Ulm

New Ulm Medical Center

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Robbinsdale

Humphrey Cancer Center at North Memorial Outpatient Center

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Saint Louis Park

Park Nicollet Cancer Center

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Saint Paul

Regions Hospital Cancer Care Center

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

United Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Shakopee

St. Francis Cancer Center at St. Francis Medical Center

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Stillwater

Lakeview Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Waconia

Ridgeview Medical Center

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Willmar

Willmar Cancer Center at Rice Memorial Hospital

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Woodbury

Minnesota Oncology - Woodbury

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Mississippi
Jackson

University of Mississippi Cancer Clinic

Louis V Puneky
Ph: 601-815-6700

Pascagoula

Regional Cancer Center at Singing River Hospital

James E. Clarkson
Ph: 228-809-5292

Missouri
Bonne Terre

Parkland Health Center-Bonne Terre

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Cape Girardeau

Saint Francis Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Southeast Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Chesterfield

Saint Luke's Hospital

Donald F. Busiek
Ph: 314-205-6936

Columbia

Ellis Fischel Cancer Center at University of Missouri - Columbia

Clint D Kingsley
Ph: 573-882-7440

Independence

Independence Regional Health Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Jefferson City

Goldschmidt Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Kansas City

Heartland Hematology Oncology Associates, Incorporated

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Research Medical Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Saint Luke's Hospital

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Lee's Summit

Saint Luke's East - Lee's Summit

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Liberty

Parvin Radiation Oncology

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Saint Joseph

Heartland Regional Medical Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Saint Louis

Barnes-Jewish West County Hospital

Maria Q. Baggstrom
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Missouri Baptist Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

Maria Q. Baggstrom
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Saint Peters

Siteman Cancer Center at Barnes-Jewish St. Peters Hospital - St. Peters

Maria Q. Baggstrom
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Sainte Genevieve

Sainte Genevieve County Memorial Hospital

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Sullivan

Missouri Baptist Sullivan Hospital

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Sunset Hills

Missouri Baptist Outpatient Center-Sunset Hills

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Montana
Billings

Billings Clinic Cancer Center - 801 N 29th Street

Benjamin Thomas Marchello
Ph: 800-648-6274

CCOP - Montana Cancer Consortium

Benjamin Thomas Marchello
Ph: 800-648-6274

St. Vincent Healthcare Cancer Care Services

Benjamin Thomas Marchello
Ph: 800-648-6274

Bozeman

Bozeman Deaconess Cancer Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Butte

St. James Healthcare Cancer Care

Benjamin Thomas Marchello
Ph: 800-648-6274

Great Falls

Benefis Sletten Cancer Institute

Benjamin Thomas Marchello
Ph: 800-648-6274

Helena

St. Peter's Hospital

Benjamin Thomas Marchello
Ph: 800-648-6274

Kalispell

Kalispell Regional Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Missoula

Community Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Montana Cancer Center at St. Patrick Hospital and Health Sciences Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Nebraska
Grand Island

Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center

Mehmet S. Copur
Ph: 800-998-2119

Kearney

Good Samaritan Cancer Center at Good Samaritan Hospital

Mehmet S. Copur
Ph: 800-998-2119

Lincoln

Cancer Resource Center - Lincoln

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Nebraska Hematology and Oncology

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Southeast Nebraska Hematology Oncology Consultants at Southeast Nebraska Cancer Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Norfolk

Carson Cancer Center at Faith Regional Hospital

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

North Platte

Callahan Cancer Center at Great Plains Regional Medical Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Omaha

Alegant Health Cancer Center at Bergan Mercy Medical Center

Mehmet S. Copur
Ph: 800-998-2119

Creighton University Medical Center

Mehmet S. Copur
Ph: 800-998-2119

Immanuel Medical Center

Mehmet S. Copur
Ph: 800-998-2119

Lakeside Hospital

Mehmet S. Copur
Ph: 800-998-2119

Methodist Estabrook Cancer Center

Tien-Shew W Huang
Ph: 402-354-5144

Oncology Hematology West PC

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Oncology Hematology West, PC - Omaha Bergan

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Papillion

Midlands Cancer Center at Midlands Community Hospital

Mehmet S. Copur
Ph: 800-998-2119

Scottsbluff

Cancer Treatment Center at Regional West Medical Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Nevada
Henderson

21st Century Oncology - Henderson

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Henderson

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Henderson

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada-Southeast Henderson

John Allan Ellerton
Ph: 702-384-0013

Las Vegas Cancer Center - Henderson

John Allan Ellerton
Ph: 702-384-0013

Las Vegas

21st Century Oncology - Fort Apache

John Allan Ellerton
Ph: 702-384-0013

21st Century Oncology - Vegas Sunrise

John Allan Ellerton
Ph: 702-384-0013

21st Century Oncology - Vegas Tenaya

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Fort Apache

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Shadow

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Tenaya

John Allan Ellerton
Ph: 702-384-0013

Cancer Institute of Nevada at Summerlin Hospital Medical Center

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Ph: 702-384-0013

Cancer Therapy and Integrative Medicine

John Allan Ellerton
Ph: 702-384-0013

CCOP - Nevada Cancer Research Foundation

John Allan Ellerton
Ph: 702-384-0013

Children's Specialty Center of Nevada

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Central Valley

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Northwest

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Southwest

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-San Martin

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

John Allan Ellerton
Ph: 702-384-0013

Las Vegas Cancer Center-Medical Center

John Allan Ellerton
Ph: 702-384-0013

Radiation Oncology Centers of Las Vegas - Downtown Location

John Allan Ellerton
Ph: 702-384-0013

Radiation Oncology Centers of Las Vegas - Eastern Location

John Allan Ellerton
Ph: 702-384-0013

University Medical Center of Southern Nevada

John Allan Ellerton
Ph: 702-384-0013

Reno

Abrass and Conrath Hematology - Oncology

Jaime H Shuff
Ph: 775-770-7414

Alpine Hematology-Oncology

Jaime H Shuff
Ph: 775-770-7414

Radiation Oncology Associates - Reno

Jaime H Shuff
Ph: 775-770-7414

Saint Mary's Regional Medical Center

Jaime H Shuff
Ph: 775-770-7414

New Hampshire
Concord

New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care

Jeffrey A. Bogart
Email: bogartj@upstate.edu

Lebanon

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center

Philip E Schaner
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

New Jersey
Basking Ridge

Memorial Sloan-Kettering Cancer Center - Basking Ridge

Andreas Rimner
Ph: 212-639-7202

Camden

Cancer Institute of New Jersey at Cooper University Hospital - Camden

Stephen Scott Grubbs
Ph: 302-733-6227

Mount Holly

Virtua Fox Chase Health Cancer Program at Virtua Memorial Hospital Burlington County

Lemuel S. Ariaratnam
Ph: 888-847-8823

Sparta

Frederick R. and Betty M. Smith Cancer Treatment Center

Maria Werner-Wasik
Ph: 215-955-6084

Voorhees

Cancer Institute of New Jersey at Cooper - Voorhees

Robert A Somer
Ph: 856-325-6757

Fox Chase Virtua Health Cancer Program at Virtua West Jersey

Lemuel S. Ariaratnam
Ph: 888-847-8823

New Mexico
Albuquerque

University of New Mexico Cancer Center

Martin J. Edelman
Ph: 800-888-8823

New York
Buffalo

Veterans Affairs Medical Center - Buffalo

Lynn Marie Steinbrenner
Ph: 716-862-3191

Canandiaqua

Sands Cancer Center

Yuhchyau Chen
Ph: 585-275-5830

Commack

Memorial Sloan-Kettering Cancer Center

Andreas Rimner
Ph: 212-639-7202

Glens Falls

Charles R. Wood Cancer Center at Glens Falls Hospital

Aqeel A Gillani
Ph: 518-926-6700

New York

Memorial Sloan-Kettering Cancer Center

Andreas Rimner
Ph: 212-639-7202

Rochester

Daisy Marquis Jones Radiation Oncology Center at Highland Hospital of Rochester

Yuhchyau Chen
Ph: 585-275-5830

James P. Wilmot Cancer Center at University of Rochester Medical Center

Yuhchyau Chen
Ph: 585-275-5830

Lipson Cancer and Blood Center at Rochester General Hospital

Meri Atanas
Ph: 585-922-3536
Email: tia.derosa@rochestergeneral.org

University Radiation Oncology at Parkridge Hospital

Yuhchyau Chen
Ph: 585-275-5830

Rockville Centre

Memorial Sloan-Kettering Cancer Center - Rockville Centre

Andreas Rimner
Ph: 212-639-7202

Sleepy Hollow

Memorial Sloan-Kettering Cancer Center at Phelps Memorial Hospital Center

Andreas Rimner
Ph: 212-639-7202

Syracuse

SUNY Upstate Medical University Hospital

Jeffrey A. Bogart
Ph: 315-464-5476

North Carolina
Asheville

Cancer Care of Western North Carolina

Christopher H Chay
Ph: 828-213-4150

Hope A Women's Cancer Center

Christopher H Chay
Ph: 828-213-4150

Mission Hospitals - Memorial Campus

Christopher H Chay
Ph: 828-213-4150

Mountain Radiation Oncology, PA

Christopher H Chay
Ph: 828-213-4150

Brevard

Transylvania Community Hospital

Christopher H Chay
Ph: 828-213-4150

Chapel Hill

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill

Jeffrey A. Bogart
Email: bogartj@upstate.edu

Charlotte

Presbyterian Cancer Center at Presbyterian Hospital

Justin P Favaro
Ph: 704-384-5369

Clinton

Southeastern Medical Oncology Center-Clinton

James N. Atkins
Ph: 919-580-0000

Durham

Duke Cancer Institute

Jeffrey Crawford
Ph: 888-275-3853

Franklin

Angel Medical Center

Christopher H Chay
Ph: 828-213-4150

Goldsboro

Southeastern Medical Oncology Center - Goldsboro

James N. Atkins
Ph: 919-580-0000

Wayne Memorial Hospital, Incorporated

James N. Atkins
Ph: 919-580-0000

Hendersonville

Comprehensive Cancer Center at Pardee Hospital

James E. Radford
Ph: 828-696-4716

Hendersonville Hematology and Oncology

James E. Radford
Ph: 828-696-4716

Park Ridge Hospital Breast Health Center

Charles E Bowers
Ph: 800-486-5941

Jacksonville

Southeastern Medical Oncology Center-Jacksonville

James N. Atkins
Ph: 919-580-0000

Kernersville

Novant Health Oncology Specialists-Kernersville

Volker W Stieber
Ph: 336-277-8887

Kinston

Kinston Medical Specialists

Peter R. Watson
Ph: 252-559-2200

Lexington

Novant Health Oncology Specialists-Davidson County

Volker W Stieber
Ph: 336-277-8887

Marion

McDowell Hospital

Christopher H Chay
Ph: 828-213-4150

Mount Airy

Novant Health Oncology Specialists-Mount Airy

Volker W Stieber
Ph: 336-277-8887

Pinehurst

FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center

Charles S Kuzma
Ph: 910-715-2200

Spruce Pine

Blue Ridge Regional Hospital

Christopher H Chay
Ph: 828-213-4150

Statesville

Iredell Memorial Hospital

Ruby A. Grimm
Ph: 704-873-5661

Stateville

Novant Health Oncology Specialists-Statesville

Volker W Stieber
Ph: 336-277-8887

Supply

South Atlantic Radiation Oncology, LLC

Michael A Papagikos
Ph: 910-251-1839

Wilkesboro

Novant Health Oncology Specialists-Wilkesboro

Volker W Stieber
Ph: 336-277-8887

Wilmington

Coastal Carolina Radiation Oncology Center

Michael A Papagikos
Ph: 910-251-1839

Zimmer Cancer Center at New Hanover Regional Medical Center

Michael A Papagikos
Ph: 910-251-1839

Wilson

Southeastern Medical Oncology Center - Wilson

James N. Atkins
Ph: 919-580-0000

Winston-Salem

Forsyth Regional Cancer Center at Forsyth Medical Center

Volker W Stieber
Ph: 336-277-8887

Piedmont Hematology-Oncology Associates

Volker W Stieber
Ph: 336-277-8887

Wake Forest University Comprehensive Cancer Center

James J Urbanic
Ph: 858-822-5354
Email: cancercto@ucsd.edu

Winston-Salem Health Care

Volker W Stieber
Ph: 336-277-8887

North Dakota
Bismarck

Bismarck Cancer Center

Edward J. Wos
Ph: 701-323-5760
Email: tfischer@mohs.org

Medcenter One Hospital Cancer Care Center

Preston D. Steen
Ph: 701-234-6161

Fargo

Roger Maris Cancer Center at MeritCare Hospital

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Ph: 701-234-6161

Sanford Clinic North-Fargo

Preston D. Steen
Ph: 701-234-6161

Grand Forks

Altru Cancer Center at Altru Hospital

Grant R Seeger
Ph: 701-780-6520

Minot

Trinity CancerCare Center

Kevin Basil Collins
Ph: 888-823-5923
Email: ctsucontact@westat.com

Ohio
Akron

McDowell Cancer Center at Akron General Medical Center

Esther H. Rehmus
Ph: 330-344-6348

Summa Center for Cancer Care at Akron City Hospital

Charles A Kunos
Ph: 330-375-6101

Barberton

Barberton Citizens Hospital

Charles A Kunos
Ph: 330-375-6101

Beachwood

UHHS Chagrin Highlands Medical Center

Gregory Videtic
Ph: 866-223-8100

Belpre

Strecker Cancer Center-Belpre

J. Philip Kuebler
Ph: 614-566-3275

Canton

Aultman Cancer Center at Aultman Hospital

Laird E Olson
Ph: 330-363-6891

Chillicothe

Adena Regional Medical Center

J. Philip Kuebler
Ph: 614-566-3275

Cincinnati

Bethesda North Hospital

Mehmet S. Copur
Ph: 800-998-2119

Good Samaritan Hospital Cancer Treatment Center

Mehmet S. Copur
Ph: 800-998-2119

University of Cincinnati

Kevin P. Redmond
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Cleveland

Case Comprehensive Cancer Center

Gregory Videtic
Ph: 866-223-8100

Cleveland Clinic Taussig Cancer Center

Gregory Videtic
Ph: 866-223-8100

Columbus

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center

Jeffrey A. Bogart
Email: bogartj@upstate.edu

Columbus Oncology Associates, Incorporated

J. Philip Kuebler
Ph: 614-566-3275

Doctors Hospital at Ohio Health

J. Philip Kuebler
Ph: 614-566-3275

Grant Medical Center Cancer Care

J. Philip Kuebler
Ph: 614-566-3275

Mount Carmel Health - West Hospital

J. Philip Kuebler
Ph: 614-566-3275

Riverside Methodist Hospital Cancer Care

J. Philip Kuebler
Ph: 614-566-3275

Zangmeister Center

J. Philip Kuebler
Ph: 614-566-3275

Delaware

Delaware Health Center

J. Philip Kuebler
Ph: 614-566-3275

Delaware Radiation Oncology

J. Philip Kuebler
Ph: 614-566-3275

Grady Memorial Hospital

J. Philip Kuebler
Ph: 614-566-3275

Independence

Cleveland Clinic Taussig Cancer Center

Gregory Videtic
Ph: 866-223-8100

Lancaster

Fairfield Medical Center

J. Philip Kuebler
Ph: 614-566-3275

Marietta

Strecker Cancer Center at Marietta Memorial Hospital

J. Philip Kuebler
Ph: 614-566-3275

Mayfield Heights

Hillcrest Cancer Center at Hillcrest Hospital

Gregory Videtic
Ph: 866-223-8100

Medina

Summa Health Center at Lake Medina

Charles A Kunos
Ph: 330-375-6101

Middleburg Heights

Southwest General Health Center

Gregory Videtic
Ph: 866-223-8100

Mount Vernon

Knox Community Hospital

J. Philip Kuebler
Ph: 614-566-3275

Newark

Licking Memorial Cancer Care Program at Licking Memorial Hospital

J. Philip Kuebler
Ph: 614-566-3275

Newark Radiation Oncology

J. Philip Kuebler
Ph: 614-566-3275

Portsmouth

Southern Ohio Medical Center Cancer Center

J. Philip Kuebler
Ph: 614-566-3275

Springfield

Community Hospital of Springfield and Clark County

J. Philip Kuebler
Ph: 614-566-3275

Westerville

Mount Carmel St. Ann's Cancer Center

J. Philip Kuebler
Ph: 614-566-3275

Westlake

UHHS Westlake Medical Center

Gregory Videtic
Ph: 866-223-8100

Wooster

Cleveland Clinic - Wooster

Gregory Videtic
Ph: 866-223-8100

Zanesville

Genesis - Good Samaritan Hospital

J. Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

Oklahoma
Oklahoma City

Stephenson Cancer Center at the University of Oklahoma

Mohammad A Razaq
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Oregon
Clackamas

Clackamas Radiation Oncology Center

Keith S. Lanier
Ph: 503-215-6412

Providence Oncology and Hematology Care Southeast

Keith S. Lanier
Ph: 503-215-6412

Newberg

Providence Newberg Medical Center

Keith S. Lanier
Ph: 503-215-6412

Oregon City

Willamette Falls Hospital

Keith S. Lanier
Ph: 503-215-6412

Portland

Providence Cancer Center at Providence Portland Medical Center

Keith S. Lanier
Ph: 503-215-6412

Providence St. Vincent Medical Center

Keith S. Lanier
Ph: 503-215-6412

The Dalles

Celilo Cancer Center at Mid-Columbia Medical Center

Keith J. Stelzer
Ph: 541-296-7585

Pennsylvania
Abington

Rosenfeld Cancer Center at Abington Memorial Hospital

Wayne H Pinover
Ph: 215-481-2402

Beaver

UPMC Cancer Center at Beaver Medical Center

Mark A. Socinski
Ph: 412-647-8073

Bryn Mawr

Bryn Mawr Hospital

Albert S DeNittis
Ph: 866-225-5654

Clairton

UPMC Cancer Center at Jefferson Regional Medical Center

Mark A. Socinski
Ph: 412-647-8073

Darby

Mercy Fitzgerald Hospital

Maria Werner-Wasik
Ph: 215-955-6084

Drexel Hill

Delaware County Regional Cancer Center at Delaware County Memorial Hospital

Rachelle M. Lanciano
Ph: 610-284-8237
Email: jolene.garney@crozer.org

East Stroudsburg

Dale and Frances Hughes Cancer Center at Pocono Medical Center

Maria Werner-Wasik
Ph: 215-955-6084

Ephrata

Ephrata Cancer Center at Ephrata Community Hospital

Amit B. Shah
Ph: 877-441-7957

Gettysburg

Adams Cancer Center

Amit B. Shah
Ph: 877-441-7957

Greensburg

UPMC Cancer Center - Arnold Palmer Pavilion

Mark A. Socinski
Ph: 412-647-8073

Hanover

Cherry Tree Cancer Center

Amit B. Shah
Ph: 877-441-7957

Hershey

Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center

Henry Wagner
Ph: 717-531-3779
Email: CTO@hmc.psu.edu

Johnstown

UPMC Cancer Center at the John P. Murtha Pavilion

Mark A. Socinski
Ph: 412-647-8073

McKeesport

UPMC Cancer Center at UPMC McKeesport

Mark A. Socinski
Ph: 412-647-8073

Meadowbrook

Charles A. & Betty Bott Cancer Center at Holy Redeemer Hospital

Pallav Mehta
Ph: 215-938-3551

Moon Township

UPMC - Moon

Mark A. Socinski
Ph: 412-647-8073

Paoli

Cancer Center of Paoli Memorial Hospital

Albert S DeNittis
Ph: 866-225-5654

Philadelphia

Abramson Cancer Center of the University of Pennsylvania

Corey Jay Langer
Ph: 800-474-9892

Albert Einstein Cancer Center

Kenneth L. Zeitzer
Ph: 215-456-3880

Frankford Hospital Cancer Center - Torresdale Campus

Maria Werner-Wasik
Ph: 215-955-6084

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia

Maria Werner-Wasik
Ph: 215-955-6084

Pittsburgh

St. Clair Memorial Hospital Cancer Center

Mark A. Socinski
Ph: 412-647-8073

UPMC - Shadyside

Mark A. Socinski
Ph: 412-647-8073

UPMC Cancer Center at UPMC Passavant

Mark A. Socinski
Ph: 412-647-8073

UPMC Cancer Center at UPMC Presbyterian

Mark A. Socinski
Ph: 412-647-8073

UPMC Cancer Center at UPMC St. Margaret

Mark A. Socinski
Ph: 412-647-8073

UPMC Cancer Centers

Mark A. Socinski
Ph: 412-647-8073

Seneca

UPMC Cancer Center at UPMC Northwest

Mark A. Socinski
Ph: 412-647-8073

Uniontown

UPMC Cancer Center - Uniontown

Mark A. Socinski
Ph: 412-647-8073

Washington

Washington Hospital Cancer Center

Mark A. Socinski
Ph: 412-647-8073

West Reading

McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

Albert Yuen
Ph: 610-988-9323

Wynnewood

Lankenau Cancer Center at Lankenau Hospital

Albert S DeNittis
Ph: 866-225-5654

York

WellSpan Health

Amit B. Shah
Ph: 877-441-7957

York Cancer Center at Apple Hill Medical Center

Amit B. Shah
Ph: 877-441-7957

South Carolina
Anderson

AnMed Cancer Center

Charles E Bowers
Ph: 800-486-5941

Charles E Bowers
Ph: 800-486-5941

Charleston

Hollings Cancer Center at Medical University of South Carolina

Anand Sharma
Ph: 843-792-9321

Greenville

Bon Secours St. Francis Health System

Robert D. Siegel
Ph: 864-255-1713

Saint Francis Cancer Center

Charles E Bowers
Ph: 800-486-5941

Greenwood

Self Regional Cancer Center at Self Regional Medical Center

Anand Sharma
Ph: 843-792-9321

Greer

Gibbs Cancer Center-Pelham

Charles E Bowers
Ph: 800-486-5941

Lancaster

Carolina Blood and Cancer Care Associates, PA

Charles E Bowers
Ph: 800-486-5941

Rock Hill

Carolina Blood and Cancer Care

Charles E Bowers
Ph: 800-486-5941

Spartanburg

Gibbs Regional Cancer Center at Spartanburg Regional Medical Center

Charles E Bowers
Ph: 800-486-5941

South Dakota
Sioux Falls

Sanford Cancer Center at Sanford USD Medical Center

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Ph: 701-234-6161

Tennessee
Bristol

Blue Ridge Medical Specialists, PC

Asheesh Shipstone
Ph: 423-578-8538

Wellmont-Bristol Regional Medical Center

Asheesh Shipstone
Ph: 423-578-8538

Chattanooga

H. Clay Evans Johnson Cancer Center at Memorial Hospital

Mehmet S. Copur
Ph: 800-998-2119

Kingsport

Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center

Asheesh Shipstone
Ph: 423-578-8538

Kingsport Hematology-Oncology Associates

Asheesh Shipstone
Ph: 423-578-8538

Knoxville

Thompson Cancer Survival Center

Daniel D Scaperoth
Ph: 865-541-1812

U.T. Medical Center Cancer Institute

Wahid T. Hanna
Ph: 865-544-9773

Texas
Amarillo

Harrington Cancer Center

Stewart Allen Sharp
Ph: 806-359-4673
Email: ryokubaitis@harringtoncc.org

Dallas

Parkland Memorial Hospital

Hak Choy
Ph: 214-648-7097

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas

Hak Choy
Ph: 214-648-7097

Galveston

University of Texas Medical Branch

Todd A Swanson
Ph: 409-772-1950
Email: clinical.research@utmb.edu

Houston

Univeristy of Texas M.D. Anderson Cancer Center

Ritsuko U. Komaki
Ph: 713-792-3245

League City

UTMB Cancer Center at Victory Lakes

Todd A Swanson
Ph: 409-772-1950
Email: clinical.research@utmb.edu

San Antonio

University of Texas Health Science Center at San Antonio

Ying Li
Ph: 210-450-3800
Email: CTO@uthscsa.edu

Vermont
Saint Johnsbury

Norris Cotton Cancer Center - North

Philip E Schaner
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Virginia
Norton

Southwest Virginia Regional Cancer Center at Wellmonth Health

Asheesh Shipstone
Ph: 423-578-8538

Washington
Bremerton

Harrison Medical Center

Mehmet S. Copur
Ph: 800-998-2119

Olympic Hematology and Oncology

Mehmet S. Copur
Ph: 800-998-2119

Burien

Highline Medical Center Cancer Center

Mehmet S. Copur
Ph: 800-998-2119

Longview

Lower Columbia Regional Cancer Center at PeaceHealth-St. John Medical Center

Keith S. Lanier
Ph: 503-215-6412

Tacoma

Northwest Medical Specialties, PLLC - Tacoma

Mehmet S. Copur
Ph: 800-998-2119

Vancouver

Southwest Washington Medical Center Cancer Center

Keith S. Lanier
Ph: 503-215-6412

West Virginia
Wheeling

Schiffler Cancer Center at Wheeling Hospital

Lowell C Shinn
Ph: 304-243-6442

Wisconsin
Fond Du Lac

Central Wisconsin Cancer Program at Agnesian HealthCare

Michael J Vander Kooy
Ph: 800-494-2927

Green Bay

Green Bay Oncology, Limited at St. Mary's Hospital

Anthony J. Jaslowski
Ph: 800-432-6049

Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center

Anthony J. Jaslowski
Ph: 800-432-6049

St. Mary's Hospital Medical Center - Green Bay

Anthony J. Jaslowski
Ph: 800-432-6049

St. Vincent Hospital Regional Cancer Center

Anthony J. Jaslowski
Ph: 800-432-6049

Johnson Creek

UW Cancer Center Johnson Creek

Bethany M Anderson
Ph: 877-405-6866

La Crosse

Gundersen Lutheran Center for Cancer and Blood

Kurt Oettel
Ph: 608-775-2385
Email: cancerctr@gundluth.org

Madison

University of Wisconsin Paul P. Carbone Comprehensive Cancer Center

Bethany M Anderson
Ph: 877-405-6866

Marinette

Bay Area Cancer Care Center at Bay Area Medical Center

Anthony J. Jaslowski
Ph: 800-432-6049

Milwaukee

Froedtert Hospital and Medical College of Wisconsin

Elizabeth M. Gore
Ph: 414-805-4380

Veterans Affairs Medical Center - Milwaukee

Elizabeth M. Gore
Ph: 414-805-4380

New Richmond

Cancer Center of Western Wisconsin

Patrick J. Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Oconto Falls

Green Bay Oncology, Limited - Oconto Falls

Anthony J. Jaslowski
Ph: 800-432-6049

Racine

All Saints Cancer Center at Wheaton Franciscan Healthcare

James H. Taylor
Ph: 414-874-4541
Email: Kelli.holton@wfhc.org

Sturgeon Bay

Door County Cancer Center at Door County Memorial Hospital

Anthony J. Jaslowski
Ph: 800-432-6049

Green Bay Oncology, Limited - Sturgeon Bay

Anthony J. Jaslowski
Ph: 800-432-6049

Wisconsin Rapids

Riverview UW Cancer Center at Riverview Hospital

Bethany M Anderson
Ph: 877-405-6866

Wyoming
Cheyenne

Cheyenne Regional Medical Center

Keren Sturtz
Ph: 888-785-6789

Cody

Big Horn Basin Cancer Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Billings Clinic-Cody

Benjamin Thomas Marchello
Ph: 800-648-6274

Sheridan

Welch Cancer Center at Sheridan Memorial Hospital

Benjamin Thomas Marchello
Ph: 800-648-6274

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT00632853
ClinicalTrials.gov processed this data on May 15, 2015

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.