Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients with Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

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Basic Trial Information

PhaseTypeAgeTrial IDs
Phase IIIBiomarker/Laboratory analysis, PreventionNot specifiedGOG-0225
NCI-2009-00595, CDR0000594600, NCT00719303

Trial Description

Summary

This randomized phase III trial studies whether changes in diet and physical activity can increase the length of survival without the return of cancer (progression-free survival) compared with usual care in patients with previously treated stage II, III, or IV ovarian, fallopian tube, or primary peritoneal cancer. A healthy diet and physical activity program and counseling may help patients make healthier lifestyle choices. It is not yet known whether changes in diet and exercise may help increase progression-free survival in patients with previously treated cancer.

Further Study Information

PRIMARY OBJECTIVE:

I. To determine if women who are disease-free after successfully completing primary and potential consolidation/maintenance, therapy for stage II-IV ovarian, fallopian tube or primary peritoneal cancer and who are randomized to a healthy lifestyle intervention, will have significantly increased progression-free survival compared to similar women who are randomized to a usual care comparison group.

SECONDARY OBJECTIVE:

I. To determine if women who are randomized to the study intervention will have improved general quality of life as measured by the General Health subscale of RAND 36-Item Health Survey (RAND-36).

II. To determine if women who are randomized to the study intervention will have improved physical and bowel functioning as measured by the Physical Functioning subscale of RAND-36 and the Gastrointestinal Symptom Rating Scale (GSRS)-Irritable Bowel Syndrome (IBS), compared to women who are randomized to usual care.

TERTIARY OBJECTIVES:

I. To assess patient compliance with the healthy lifestyle intervention by analyzing biomarkers (e.g., total carotenoid) at baseline, 6, 12, and 24 months.

II. To explore the relationship between carotenoid exposure and progression free survival from ovarian cancer.

III. To examine patient compliance with the healthy lifestyle intervention and to assess which types of patients are more likely to be compliant with the healthy lifestyle intervention and whether progression-free survival is better among compliant individuals.

IV. To explore the impact of the intervention on other aspects of quality of life such as pain, role limitations due to physical health and emotional problems, mental health, vitality, and social functioning as measured by the corresponding subscales of the RAND-36.

V. To explore the impact of the intervention on bowel functioning as measured with the GSRS-IBS subscales.

VI. To assess the association between subjectively measured sleep duration/quality (using the Pittsburgh Sleep Quality Scale), anthropometric measurements, and self-reported dietary energy intake among women previously treated for stage II-IV ovarian or primary peritoneal cancer.

VII. To assess and compare telomere length and rate of telomere shortening between ovarian cancer survivors randomized to lifestyle intervention versus standard of care.

OUTLINE: Participants are randomized to 1 of 2 groups.

GROUP 1 (LIFESTYLE INTERVENTION): Participants receive a dietary intervention designed to promote increased levels of plasma carotenoids, control weight, and to ensure adequacy of micronutrient intake. Participants also undergo a physical activity intervention comprising a moderately low aerobic regimen to raise the usual activity level. Participants also undergo face-to-face counseling, receive educational materials and counseling focused on how to read food labels to estimate grams of fat per serving and serving size, and undergo telephone counseling by a lifestyle intervention counselor twice a week for 4 weeks, then weekly for 2 weeks, twice a month for 5 months, monthly for the subsequent 6 months, and then once every other month for 12 months. Participants complete daily fat gram and step diaries at least three times per week.

GROUP 2 (COMPARISON LIFESTYLE): Participants receive a study notebook containing general study-related information. Participants are not asked to record diet or physical activity but are provided a single sample diary in their study notebook. Participants receive telephone contact on a sliding scale similar to the intervention group, but at less frequent intervals (22 versus 33 calls over the course of the intervention).

After completion of study, participants are followed up every 3 months for 2 years, every 6 months for 3 years, and then annually thereafter.

Eligibility Criteria

Inclusion Criteria:

Patients must have achieved a documented complete response to treatment based on normal cancer antigen (CA)-125 (per the institution’s upper limit of normal) and computed tomography (CT) scan or magnetic resonance imaging (MRI) with contrast (i.e. there must be no clinical evidence of persistent or recurrent disease based on CA-125 and CT scan or MRI with contrast)

Patients with a histological diagnosis of epithelial ovarian cancer, fallopian tube or primary peritoneal carcinoma, clinical stage II, III or IV at diagnosis

Patients with the following histologic epithelial cell types are eligible: serous adenocarcinoma, endometrioid adenocarcinoma, mucinous adenocarcinoma, undifferentiated carcinoma, clear cell adenocarcinoma, mixed epithelial carcinoma, transitional cell carcinoma, malignant Brenner’s Tumor or adenocarcinoma not otherwise specified (N.O.S.); however, the histologic features of the tumor must be compatible with a primary Müllerian epithelial adenocarcinoma

Patients must have completed all primary chemotherapy and consolidation therapy (if administered) at least 6 weeks, and no more than 6 months and 2 weeks, prior to enrollment and must be in complete remission; consolidation therapy is defined as any chemotherapy or biological therapy used for a patient who has completed at least four courses of primary chemotherapy and had documented complete remission prior to initiation of such chemotherapy or biological therapy

Patients must be willing to provide name and appropriate telephone contact information and be willing to be contacted periodically via telephone by The University of Arizona Cancer Center (AZCC) staff for completion of individualized lifestyle intervention coaching, completion of the Pittsburgh Sleep Quality Index, and for clarification of patient-completed responses if necessary; patient must be willing to have Arizona Food Frequency Questionnaire (AFFQ), Arizona Physical Activity Questionnaire (APAQ), baseline questionnaire, and personal contact information sent to AZCC

Patients must not have a serious psychiatric illness (e.g. lifetime bipolar disorder, schizophrenia or other psychosis, serious personality disorder, severe major depressive disorder or recent suicide or psychiatric hospitalization (previous 12 months)

Patients must have signed an approved informed consent and authorization permitting release of personal health information

Patients must complete all pre-entry assessments

Patients must have a Gynecologic Oncology Group (GOG) performance grade of 0, 1, or 2

Patients must not be currently enrolled in an ongoing (participating for 6 months or longer) medically prescribed diet or physical activity regimen

Patients must have no other chronic disease that would preclude randomization into a lifestyle intervention trial; such diseases include recent myocardial infarction or unstable angina (in the previous 6 months), chronic hepatitis, rheumatoid disease, renal or hepatic disease/dysfunction and diabetics receiving insulin; or other clinical condition limiting ability to walk (recent leg fracture, significant osteoarthritis, related orthopedic conditions, degenerative neurological conditions, etc.)

Exclusion Criteria:

Patients enrolled in a weight loss program or who are taking weight loss medications or dietary supplements and are unwilling to discontinue

Patients with GOG performance grade of 3 or 4

Patients may not have a history of other invasive malignancies within the last five years, with the exception of non-melanoma skin cancer or stage 1A endometrioid adenocarcinoma of the uterus

Patients with a life expectancy of less than one year

Patients with Body Mass Index (BMI) < 20 kg/m^2

Vegan vegetarians

Patients who have had surgery for weight loss

Patients diagnosed with chronic disease/illness precluding their participation (i.e., diabetics receiving insulin, myocardial infarction or unstable angina within previous 6 months, chronic hepatitis, rheumatoid disease, renal or hepatic disease/dysfunction)

Patients who are currently undergoing treatment (primary or consolidation) for stage II, III or IV ovarian, fallopian tube or primary peritoneal cancer or who completed treatment less than six weeks ago

Patients with a histological diagnosis of clinical stage I epithelial ovarian cancer, fallopian tube or primary peritoneal carcinoma

Patients who have participated in a marathon, triathlon, or other endurance-related physical activity within the previous 24 months

Trial Contact Information

Trial Lead Organizations / Sponsors / Collaborators

NRG Oncology

  • National Cancer Institute
David S. Alberts, Principal Investigator

Trial Sites

U.S.A.

Alabama
Birmingham

University of Alabama at Birmingham Cancer Center

Warner King Huh
Ph: 205-934-0309

Warner King Huh
Principal Investigator

Huntsville

Tennessee Valley Gynecologic Oncology

David Bryan Engle
Ph: 256-533-6233

David Bryan Engle
Principal Investigator

Alaska
Fairbanks

Fairbanks Memorial Hospital

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Arizona
Phoenix

Saint Joseph's Hospital and Medical Center

Dana Meredith Chase
Ph: 877-602-4111

Dana Meredith Chase
Principal Investigator

Arkansas
Little Rock

University of Arkansas for Medical Sciences

Alexander Ferguson Burnett
Ph: 501-686-8274

Alexander Ferguson Burnett
Principal Investigator

California
Auburn

Sutter Auburn Faith Hospital

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sutter Cancer Centers Radiation Oncology Services-Auburn

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Berkeley

Alta Bates Summit Medical Center-Herrick Campus

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Burlingame

Mills - Peninsula Hospitals

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Cameron Park

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Castro Valley

Eden Hospital Medical Center

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Concord

John Muir Medical Center-Concord Campus

Babak Edraki
Ph: 925-674-2580

Babak Edraki
Principal Investigator

Davis

Sutter Davis Hospital

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

La Jolla

UC San Diego Moores Cancer Center

David S. Alberts
Ph: 520-626-7685
Email: dalberts@uacc.arizona.edu

David S. Alberts
Principal Investigator

Los Angeles

Cedars-Sinai Medical Center

Bobbie Jo Rimel
Ph: 310-423-3348
Email: paula.anastasia@cshs.org

Bobbie Jo Rimel
Principal Investigator

Kaiser Permanente Los Angeles Medical Center

Scott E. Lentz
Ph: 626-564-3455

Scott E. Lentz
Principal Investigator

Los Angeles County-USC Medical Center

Huyen Q. Pham
Ph: 323-865-0451

Huyen Q. Pham
Principal Investigator

UCLA / Jonsson Comprehensive Cancer Center

Robin Farias-Eisner
Ph: 888-798-0719

Robin Farias-Eisner
Principal Investigator

USC / Norris Comprehensive Cancer Center

Huyen Q. Pham
Ph: 323-865-0451

Huyen Q. Pham
Principal Investigator

Modesto

Memorial Medical Center

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Mountain View

Palo Alto Medical Foundation-Camino Division

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Palo Alto Medical Foundation-Gynecologic Oncology

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Orange

Saint Joseph Hospital - Orange

Michael L. Berman
Ph: 877-827-8839
Email: ucstudy@uci.edu

Michael L. Berman
Principal Investigator

Palo Alto

Palo Alto Medical Foundation Health Care

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Roseville

Sutter Cancer Centers Radiation Oncology Services-Roseville

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sutter Roseville Medical Center

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sacramento

Sutter General Hospital

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

University of California Davis Comprehensive Cancer Center

Edwin Alexander Alvarez
Ph: 916-734-3089

Edwin Alexander Alvarez
Principal Investigator

San Francisco

California Pacific Medical Center-Pacific Campus

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Santa Cruz

Palo Alto Medical Foundation-Santa Cruz

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Santa Rosa

Sutter Pacific Medical Foundation

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sunnyvale

Palo Atlo Medical Foundation-Sunnyvale

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sylmar

Olive View-University of California Los Angeles Medical Center

Christine H. Holschneider
Ph: 888-798-0719

Christine H. Holschneider
Principal Investigator

Vacaville

Sutter Cancer Centers Radiation Oncology Services-Vacaville

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Vallejo

Sutter Solano Medical Center/Cancer Center

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Walnut Creek

John Muir Medical Center-Walnut Creek

Babak Edraki
Ph: 925-674-2580

Babak Edraki
Principal Investigator

Colorado
Aurora

Rocky Mountain Cancer Centers-Aurora

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

The Medical Center of Aurora

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

University of Colorado Cancer Center - Anschutz Cancer Pavilion

Susan A. Davidson
Ph: 720-848-0650

Susan A. Davidson
Principal Investigator

Boulder

Boulder Community Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Boulder

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Colorado Springs

Penrose-Saint Francis Healthcare

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Penrose

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Denver

Colorado Blood Cancer Institute

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Colorado Cancer Research Program CCOP

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Exempla Saint Joseph Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Porter Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Presbyterian - Saint Lukes Medical Center - Health One

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Midtown

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Rose

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rose Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Durango

Mercy Medical Center

Cynthia K. Cathcart
Ph: 888-785-6789

Cynthia K. Cathcart
Principal Investigator

Southwest Oncology PC

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Englewood

Comprehensive Cancer Care and Research Institute of Colorado LLC

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Swedish Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Fort Collins

Poudre Valley Hospital

Ann Louise Stroh
Ph: 970-203-7083

Ann Louise Stroh
Principal Investigator

Golden

Mountain Blue Cancer Care Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Greeley

North Colorado Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Greenwood Village

Rocky Mountain Cancer Centers-Greenwood Village

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Lakewood

Rocky Mountain Cancer Centers-Lakewood

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Saint Anthony Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Littleton

Littleton Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Littleton

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Lone Tree

Rocky Mountain Cancer Centers-Sky Ridge

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Sky Ridge Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Longmont

Longmont United Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Longmont

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Loveland

McKee Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Parker

Parker Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Parker

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Pueblo

Rocky Mountain Cancer Centers - Pueblo

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Saint Mary Corwin Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Thornton

Rocky Mountain Cancer Centers-Thornton

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Wheat Ridge

SCL Health Lutheran Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Connecticut
Danbury

Danbury Hospital

Robert A. Kloss
Ph: 203-739-8074

Robert A. Kloss
Principal Investigator

Farmington

University of Connecticut

Angela S. Kueck
Ph: 800-579-7822

Angela S. Kueck
Principal Investigator

Hartford

Hartford Hospital

James S. Hoffman
Ph: 860-224-5660

James S. Hoffman
Principal Investigator

Saint Francis Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Middletown

Middlesex Hospital

Susanna Hong
Ph: 860-358-2058

Susanna Hong
Principal Investigator

New Britain

The Hospital of Central Connecticut

James S. Hoffman
Ph: 860-224-5660

James S. Hoffman
Principal Investigator

New Haven

Yale University

Elena S. Ratner
Ph: 203-785-5702

Elena S. Ratner
Principal Investigator

Delaware
Lewes

Beebe Medical Center

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Newark

Christiana Care Health System-Christiana Hospital

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Christiana Gynecologic Oncology LLC

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Delaware Clinical and Laboratory Physicians PA

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Helen F Graham Cancer Center

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Medical Oncology Hematology Consultants PA

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Regional Hematology and Oncology PA

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Rehoboth Beach

Beebe Health Campus

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Seaford

Nanticoke Memorial Hospital

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Wilmington

Christiana Care Health System-Wilmington Hospital

Mark Eliot Borowsky
Ph: 302-733-6227

Mark Eliot Borowsky
Principal Investigator

Florida
Sarasota

Sarasota Memorial Hospital

James Vincent Fiorica
Ph: 941-917-2225

James Vincent Fiorica
Principal Investigator

Georgia
Atlanta

Piedmont Hospital

John Warren McBroom
Email: ORS@piedmont.org

John Warren McBroom
Principal Investigator

Augusta

Georgia Regents University Medical Center

Sharad Anant Ghamande
Ph: 706-721-1663
Email: cancer@georgiahealth.edu

Sharad Anant Ghamande
Principal Investigator

Columbus

John B Amos Cancer Center

Gregory Peter Sfakianos
Ph: 706-660-6404

Gregory Peter Sfakianos
Principal Investigator

Gainesville

Northeast Georgia Medical Center

Andrew Emmons Green
Ph: 770-219-8800
Email: cancerpatient.navigator@nghs.com

Andrew Emmons Green
Principal Investigator

Savannah

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

William Edward Richards
Ph: 800-622-6877

William Edward Richards
Principal Investigator

Hawaii
Honolulu

Kapiolani Medical Center for Women and Children

Michael Ethan Carney
Ph: 808-983-6090

Michael Ethan Carney
Principal Investigator

Oncare Hawaii Inc-POB II

Michael Ethan Carney
Ph: 808-983-6090

Michael Ethan Carney
Principal Investigator

Queen's Medical Center

Michael Ethan Carney
Ph: 808-983-6090

Michael Ethan Carney
Principal Investigator

University of Hawaii Cancer Center

Michael Ethan Carney
Ph: 808-983-6090

Michael Ethan Carney
Principal Investigator

Idaho
Boise

Saint Alphonsus Cancer Care Center-Boise

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Saint Luke's Mountain States Tumor Institute

Paul G. Montgomery
Ph: 800-845-4624

Paul G. Montgomery
Principal Investigator

Fruitland

Saint Luke's Mountain States Tumor Institute - Fruitland

Paul G. Montgomery
Ph: 800-845-4624

Paul G. Montgomery
Principal Investigator

Meridian

Saint Luke's Mountain States Tumor Institute - Meridian

Paul G. Montgomery
Ph: 800-845-4624

Paul G. Montgomery
Principal Investigator

Nampa

Saint Luke's Mountain States Tumor Institute - Nampa

Paul G. Montgomery
Ph: 800-845-4624

Paul G. Montgomery
Principal Investigator

Twin Falls

Saint Luke's Mountain States Tumor Institute-Twin Falls

Paul G. Montgomery
Ph: 800-845-4624

Paul G. Montgomery
Principal Investigator

Illinois
Bloomington

Illinois CancerCare-Bloomington

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Saint Joseph Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Canton

Illinois CancerCare-Canton

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Carbondale

Memorial Hospital of Carbondale

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Carthage

Illinois CancerCare-Carthage

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Centralia

Centralia Oncology Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Chicago

Northwestern University

Emily Berry
Ph: 312-695-1301
Email: cancer@northwestern.edu

Emily Berry
Principal Investigator

Rush University Medical Center

Summer B. Dewdney
Ph: 312-942-5498
Email: clinical_trials@rush.edu

Summer B. Dewdney
Principal Investigator

University of Chicago Comprehensive Cancer Center

Meaghan Elizabeth Tenney
Ph: 773-834-7424

Meaghan Elizabeth Tenney
Principal Investigator

Danville

Carle on Vermilion

Maria T. Grosse-Perdekamp
Ph: 800-446-5532

Maria T. Grosse-Perdekamp
Principal Investigator

Decatur

Cancer Care Center of Decatur

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Decatur Memorial Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Effingham

Carle Physician Group-Effingham

Maria T. Grosse-Perdekamp
Ph: 800-446-5532

Maria T. Grosse-Perdekamp
Principal Investigator

Crossroads Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Eureka

Illinois CancerCare-Eureka

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Galesburg

Illinois CancerCare Galesburg

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Western Illinois Cancer Treatment Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Hinsdale

Sudarshan K Sharma MD Limted-Gynecologic Oncology

Sudarshan K. Sharma
Ph: 630-856-6757

Sudarshan K. Sharma
Principal Investigator

Kewanee

Illinois CancerCare-Kewanee Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Macomb

Illinois CancerCare-Macomb

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Mattoon

Carle Physician Group-Mattoon/Charleston

Maria T. Grosse-Perdekamp
Ph: 800-446-5532

Maria T. Grosse-Perdekamp
Principal Investigator

Mount Vernon

Good Samaritan Regional Health Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

New Lennox

UC Comprehensive Cancer Center at Silver Cross

Meaghan Elizabeth Tenney
Ph: 773-834-7424

Meaghan Elizabeth Tenney
Principal Investigator

Ottawa

Illinois CancerCare-Ottawa Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Radiation Oncology of Northern Illinois

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Pekin

Illinois CancerCare-Pekin

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Pekin Cancer Treatment Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Peoria

Illinois CancerCare-Peoria

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Methodist Medical Center of Illinois

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Peru

Illinois CancerCare-Peru

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Valley Radiation Oncology

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Princeton

Illinois CancerCare-Princeton

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Springfield

Memorial Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Southern Illinois University School of Medicine

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Swansea

Cancer Care Specialists of Illinois-Swansea

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Urbana

Carle Cancer Center

Maria T. Grosse-Perdekamp
Ph: 800-446-5532

Maria T. Grosse-Perdekamp
Principal Investigator

The Carle Foundation Hospital

Maria T. Grosse-Perdekamp
Ph: 800-446-5532

Maria T. Grosse-Perdekamp
Principal Investigator

Indiana
Crown Point

Michiana Hematology Oncology PC-Crown Point

Michael W. Method
Ph: 574-237-1328

Michael W. Method
Principal Investigator

Elkhart

Michiana Hematology Oncology PC-Elkhart

Michael Rodriguez
Ph: 574-237-1328

Michael Rodriguez
Principal Investigator

Indianapolis

Indiana University/Melvin and Bren Simon Cancer Center

Jeanne Marie Schilder
Ph: 317-274-2552

Jeanne Marie Schilder
Principal Investigator

Saint Vincent Oncology Center

Gregory P. Sutton
Ph: 574-237-1328

Gregory P. Sutton
Principal Investigator

Mishawaka

Michiana Hematology Oncology PC-Mishawaka

Michael W. Method
Ph: 574-237-1328

Michael W. Method
Principal Investigator

Plymouth

Michiana Hematology Oncology PC-Plymouth

Michael W. Method
Ph: 574-237-1328

Michael W. Method
Principal Investigator

South Bend

Michiana Hematology Oncology PC-South Bend

Michael W. Method
Ph: 574-237-1328

Michael W. Method
Principal Investigator

Northern Indiana Cancer Research Consortium CCOP

Michael W. Method
Ph: 574-237-1328

Michael W. Method
Principal Investigator

Westville

Michiana Hematology Oncology PC-Westville

Michael Rodriguez
Ph: 574-237-1328

Michael Rodriguez
Principal Investigator

Kansas
Chanute

Cancer Center of Kansas - Chanute

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Dodge City

Cancer Center of Kansas - Dodge City

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

El Dorado

Cancer Center of Kansas - El Dorado

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Fort Scott

Cancer Center of Kansas - Fort Scott

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Independence

Cancer Center of Kansas-Independence

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Kansas City

University of Kansas Cancer Center

Gary Alan Johnson
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Gary Alan Johnson
Principal Investigator

Kingman

Cancer Center of Kansas-Kingman

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Lawrence

Lawrence Memorial Hospital

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Liberal

Cancer Center of Kansas-Liberal

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Newton

Cancer Center of Kansas - Newton

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Overland Park

Menorah Medical Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Saint Luke's South Hospital

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Parsons

Cancer Center of Kansas - Parsons

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Pratt

Cancer Center of Kansas - Pratt

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Salina

Cancer Center of Kansas - Salina

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Wellington

Cancer Center of Kansas - Wellington

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Wichita

Associates In Womens Health

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Cancer Center of Kansas - Main Office

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Cancer Center of Kansas-Wichita Medical Arts Tower

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Via Christi Regional Medical Center

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Winfield

Cancer Center of Kansas - Winfield

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Kentucky
Edgewood

Saint Elizabeth Medical Center South

Jack B. Basil
Ph: 513-862-2230

Jack B. Basil
Principal Investigator

Lexington

University of Kentucky/Markey Cancer Center

Frederick Rand Ueland
Ph: 859-257-3379

Frederick Rand Ueland
Principal Investigator

Louisville

Norton Hospital Pavilion and Medical Campus

Mary Evelyn Gordinier
Ph: 502-629-2500

Mary Evelyn Gordinier
Principal Investigator

Norton Suburban Hospital and Medical Campus

Mary Evelyn Gordinier
Ph: 502-629-2500

Mary Evelyn Gordinier
Principal Investigator

Louisiana
Baton Rouge

Woman's Hospital

Giles Fort
Ph: 225-231-5296
Email: Ericka.Seidemann@womans.org

Giles Fort
Principal Investigator

New Orleans

Tulane University Health Sciences Center

Hana F. Safah
Ph: 504-988-6121

Hana F. Safah
Principal Investigator

Maine
Scarborough

Maine Medical Center- Scarborough Campus

Christopher J. Darus
Ph: 207-885-7565

Christopher J. Darus
Principal Investigator

Maryland
Baltimore

Greater Baltimore Medical Center

Paul Celano
Ph: 443-849-3706

Paul Celano
Principal Investigator

Bethesda

Walter Reed National Military Medical Center

Michael P. Stany
Ph: 301-319-2100

Michael P. Stany
Principal Investigator

Massachusetts
Boston

Tufts Medical Center

Young Bae Kim
Ph: 617-636-5000
Email: ContactUsCancerCenter@TuftsMedicalCenter.org

Young Bae Kim
Principal Investigator

Burlington

Lahey Hospital and Medical Center

Corrine Lenahan Zarwan
Ph: 781-744-8027

Corrine Lenahan Zarwan
Principal Investigator

Worcester

University of Massachusetts Memorial Health Care

Susan Lee Zweizig
Ph: 508-856-3216
Email: cancer.research@umassmed.edu

Susan Lee Zweizig
Principal Investigator

Michigan
Ann Arbor

Saint Joseph Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

University of Michigan Comprehensive Cancer Center

David S. Alberts
Ph: 520-626-7685
Email: dalberts@azcc.arizona.edu

David S. Alberts
Principal Investigator

Battle Creek

Bronson Battle Creek

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Dearborn

Oakwood Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Detroit

Saint John Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Wayne State University/Karmanos Cancer Institute

Robert Thomas Morris
Ph: 313-576-9363

Robert Thomas Morris
Principal Investigator

Farmington Hills

Weisberg Cancer Treatment Center

Robert Thomas Morris
Ph: 313-576-9363

Robert Thomas Morris
Principal Investigator

Flint

Genesys Hurley Cancer Institute

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Hurley Medical Center

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Grand Rapids

Mercy Health Saint Mary's

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Spectrum Health at Butterworth Campus

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Jackson

Allegiance Health

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Kalamazoo

Borgess Medical Center

Raymond Sterling Lord
Ph: 269-373-7458

Raymond Sterling Lord
Principal Investigator

Bronson Methodist Hospital

Raymond Sterling Lord
Ph: 269-373-7458

Raymond Sterling Lord
Principal Investigator

West Michigan Cancer Center

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Lansing

Sparrow Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Livonia

Saint Mary Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Muskegon

Mercy Health Mercy Campus

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Niles

Lakeland Community Hospital

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Pontiac

Saint Joseph Mercy Oakland

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Port Huron

Saint Joseph Mercy Port Huron

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Reed City

Spectrum Health Reed City Hospital

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Royal Oak

William Beaumont Hospital-Royal Oak

Jayson B. Field
Ph: 248-551-7695

Jayson B. Field
Principal Investigator

Saginaw

Saint Mary's of Michigan

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Saint Joseph

Marie Yeager Cancer Center

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

St. Joseph

Lakeland Hospital

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Traverse City

Munson Medical Center

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Troy

William Beaumont Hospital - Troy

Jayson B. Field
Ph: 248-551-7695

Jayson B. Field
Principal Investigator

Warren

Saint John Macomb-Oakland Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Minnesota
Bemidji

Sanford Clinic North-Bemidgi

Maria Caroline Bell
Ph: 218-333-5000

Maria Caroline Bell
Principal Investigator

Burnsville

Fairview Ridges Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Coon Rapids

Mercy Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Edina

Fairview-Southdale Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Fridley

Unity Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Hutchinson

Hutchinson Area Health Care

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Maplewood

Minnesota Oncology Hematology PA-Maplewood

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Saint John's Hospital - Healtheast

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Minneapolis

Abbott-Northwestern Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Health Partners Inc

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Hennepin County Medical Center

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

New Ulm

New Ulm Medical Center

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Robbinsdale

North Memorial Medical Health Center

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Saint Louis Park

Park Nicollet Clinic - Saint Louis Park

Michaela L. Tsai
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Michaela L. Tsai
Principal Investigator

Saint Paul

Regions Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

United Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Shakopee

Saint Francis Regional Medical Center

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Stillwater

Lakeview Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Waconia

Ridgeview Medical Center

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Willmar

Rice Memorial Hospital

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Woodbury

Minnesota Oncology and Hematology PA-Woodbury

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Mississippi
Jackson

Saint Dominic-Jackson Memorial Hospital

Donald Paul Seago
Ph: 601-200-3300

Donald Paul Seago
Principal Investigator

Missouri
Cape Girardeau

Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Independence

Centerpoint Medical Center LLC

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Kansas City

Heartland Hematology and Oncology Associates Incorporated

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Research Medical Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Saint Luke's Hospital of Kansas City

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Lee's Summit

Saint Luke's East - Lee's Summit

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Liberty

Liberty Radiation Oncology Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Rolla

Phelps County Regional Medical Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Saint John's Clinic-Rolla-Cancer and Hematology

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Saint Joseph

Heartland Regional Medical Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Saint Louis

Washington University School of Medicine

David Gardner Mutch
Ph: 800-600-3606
Email: info@ccadmin.wustl.edu

David Gardner Mutch
Principal Investigator

Springfield

CoxHealth South Hospital

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Mercy Hospital Springfield

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Montana
Billings

Billings Clinic Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Montana Cancer Consortium CCOP

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Saint Vincent Healthcare

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Bozeman

Bozeman Deaconess Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Butte

Saint James Community Hospital and Cancer Treatment Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Great Falls

Benefis Healthcare- Sletten Cancer Institute

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Helena

Saint Peter's Community Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Kalispell

Kalispell Regional Medical Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Missoula

Saint Patrick Hospital - Community Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Nebraska
Omaha

Nebraska Methodist Hospital

Peter Craig Morris
Ph: 402-354-7939
Email: kathryn.bartz@nmhs.org

Peter Craig Morris
Principal Investigator

Nevada
Las Vegas

Women's Cancer Center of Nevada

Nicola M. Spirtos
Ph: 702-851-4672

Nicola M. Spirtos
Principal Investigator

Reno

Center of Hope at Renown Medical Center

Peter Christopher-Why Lim
Ph: 866-513-8227

Peter Christopher-Why Lim
Principal Investigator

Renown Regional Medical Center

Peter Christopher-Why Lim
Ph: 866-513-8227

Peter Christopher-Why Lim
Principal Investigator

New Hampshire
Dover

Wentworth-Douglass Hospital

John Orland Schorge
Ph: 877-726-5130

John Orland Schorge
Principal Investigator

Lebanon

Dartmouth Hitchcock Medical Center

Leslie R. DeMars
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Leslie R. DeMars
Principal Investigator

New Jersey
Brick

Ocean Medical Center

Michael R. Manuel
Ph: 732-776-4240

Michael R. Manuel
Principal Investigator

Camden

Cooper Hospital University Medical Center

David Philip Warshal
Ph: 856-325-6757

David Philip Warshal
Principal Investigator

Hackensack

Hackensack University Medical Center

Donna Trauth McNamara
Ph: 201-996-2879

Donna Trauth McNamara
Principal Investigator

Mount Holly

Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County

Randolph Bruce Deger
Ph: 888-847-8823

Randolph Bruce Deger
Principal Investigator

Neptune

Jersey Shore Medical Center

Michael R. Manuel
Ph: 732-776-4240

Michael R. Manuel
Principal Investigator

Red Bank

Riverview Medical Center/Booker Cancer Center

Michael R. Manuel
Ph: 732-776-4240

Michael R. Manuel
Principal Investigator

Voorhees

MD Anderson Cancer Center at Cooper-Voorhees

David Philip Warshal
Ph: 856-325-6757

David Philip Warshal
Principal Investigator

Virtua West Jersey Hospital Voorhees

Randolph Bruce Deger
Ph: 888-847-8823

Randolph Bruce Deger
Principal Investigator

New Mexico
Albuquerque

Southwest Gynecologic Oncology Associates Inc

Teresa L. Rutledge
Ph: 505-272-6972

Teresa L. Rutledge
Principal Investigator

University of New Mexico

Teresa L. Rutledge
Ph: 505-272-6972

Teresa L. Rutledge
Principal Investigator

New York
Albany

Women's Cancer Care Associates LLC

Daniel Casey Kredentser
Ph: 518-458-1390

Daniel Casey Kredentser
Principal Investigator

Manhasset

North Shore University Hospital

Veena Susan John
Ph: 516-562-3467

Veena Susan John
Principal Investigator

New Hyde Park

Long Island Jewish Medical Center

Veena Susan John
Ph: 516-562-3467

Veena Susan John
Principal Investigator

North Shore-LIJ Health System/Center for Advanced Medicine

Veena Susan John
Ph: 516-562-3467

Veena Susan John
Principal Investigator

Stony Brook

Stony Brook University Medical Center

Michael L. Pearl
Ph: 800-862-2215

Michael L. Pearl
Principal Investigator

Syracuse

State University of New York Upstate Medical University

Mary Jadhon Cunningham
Ph: 315-464-5476

Mary Jadhon Cunningham
Principal Investigator

Valhalla

Westchester Medical Center

Sean Shaheen Tedjarati
Ph: 800-862-2215

Sean Shaheen Tedjarati
Principal Investigator

North Carolina
Asheboro

Randolph Hospital

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Burlington

Cone Health Cancer Center at Alamance Regional

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Chapel Hill

University of North Carolina at Chapel Hill

Linda Van Le
Ph: 877-668-0683
Email: cancerclinicaltrials@med.unc.edu

Linda Van Le
Principal Investigator

Charlotte

Carolinas Medical Center/Levine Cancer Institute

Robert Victor Higgins
Ph: 704-355-2884

Robert Victor Higgins
Principal Investigator

Novant Health Presbyterian Medical Center

John Matthew McDonald
Ph: 704-384-5369

John Matthew McDonald
Principal Investigator

Concord

Carolinas HealthCare System NorthEast

Brigitte Eva Miller
Ph: 704-403-1520

Brigitte Eva Miller
Principal Investigator

Durham

Duke University Medical Center

Laura J. Havrilesky
Ph: 888-275-3853

Laura J. Havrilesky
Principal Investigator

Greensboro

Cone Health Cancer Center

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Kernersville

Novant Health Oncology Specialists-Kernersville

Arvind Nanik Bakhru
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Arvind Nanik Bakhru
Principal Investigator

Lexington

Novant Health Oncology Specialists-Davidson County

Arvind Nanik Bakhru
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Arvind Nanik Bakhru
Principal Investigator

Mebane

Cone Heath Cancer Center at Mebane

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Mount Airy

Novant Health Oncology Specialists-Mount Airy

Arvind Nanik Bakhru
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Arvind Nanik Bakhru
Principal Investigator

Pinehurst

FirstHealth of the Carolinas-Moore Regional Hosiptal

John W. Byron
Ph: 910-715-2200

John W. Byron
Principal Investigator

Reidsville

Annie Penn Memorial Hospital

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Stateville

Novant Health Oncology Specialists-Statesville

Arvind Nanik Bakhru
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Arvind Nanik Bakhru
Principal Investigator

Wilkesboro

Novant Health Oncology Specialists-Wilkesboro

Arvind Nanik Bakhru
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Arvind Nanik Bakhru
Principal Investigator

Winston-Salem

Novant Health Oncology Specialists

Arvind Nanik Bakhru
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Arvind Nanik Bakhru
Principal Investigator

Winston-Salem Health Care

Arvind Nanik Bakhru
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Arvind Nanik Bakhru
Principal Investigator

North Dakota
Bismarck

Sanford Bismarck Medical Center

Maria Caroline Bell
Ph: 218-333-5000

Maria Caroline Bell
Principal Investigator

Fargo

Roger Maris Cancer Center

Maria Caroline Bell
Ph: 218-333-5000

Maria Caroline Bell
Principal Investigator

Sanford Clinic North-Fargo

Maria Caroline Bell
Ph: 218-333-5000

Maria Caroline Bell
Principal Investigator

Sanford Medical Center-Fargo

Maria Caroline Bell
Ph: 218-333-5000

Maria Caroline Bell
Principal Investigator

Ohio
Canton

Aultman Health Foundation

Michael P. Hopkins
Ph: 330-363-6891

Michael P. Hopkins
Principal Investigator

Cincinnati

Bethesda North Hospital

James Clifford Pavelka
Ph: 513-862-2230

James Clifford Pavelka
Principal Investigator

Good Samaritan Hospital - Cincinnati

James Clifford Pavelka
Ph: 513-862-2230

James Clifford Pavelka
Principal Investigator

Columbus

Ohio State University Comprehensive Cancer Center

David M. O'Malley
Ph: 800-293-5066
Email: Jamesline@osumc.edu

David M. O'Malley
Principal Investigator

Sylvania

Flower Hospital

Rex B. Mowat
Ph: 800-444-3561

Rex B. Mowat
Principal Investigator

Toledo

University of Toledo

Rex B. Mowat
Ph: 800-444-3561

Rex B. Mowat
Principal Investigator

Oklahoma
Oklahoma City

University of Oklahoma Health Sciences Center

Robert S. Mannel
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Robert S. Mannel
Principal Investigator

Tulsa

Tulsa Cancer Institute

Robert S. Mannel
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Robert S. Mannel
Principal Investigator

Pennsylvania
Abington

Abington Memorial Hospital

Parviz Hanjani
Ph: 215-481-2402

Parviz Hanjani
Principal Investigator

Bethlehem

Saint Luke's University Hospital-Bethlehem Campus

Nicholas P. Taylor
Ph: 610-954-3582
Email: infolink@slhn.org

Nicholas P. Taylor
Principal Investigator

Danville

Geisinger Medical Center

Radhika P. Gogoi
Ph: 570-271-5251

Radhika P. Gogoi
Principal Investigator

Gettysburg

Adams Cancer Center

Mark A. Miller
Ph: 877-441-7957

Mark A. Miller
Principal Investigator

Hazleton

Geisinger Medical Center-Cancer Center Hazleton

Radhika P. Gogoi
Ph: 570-271-5251

Radhika P. Gogoi
Principal Investigator

Philadelphia

University of Pennsylvania/Abramson Cancer Center

Robert Allen Burger
Ph: 215-746-7406

Robert Allen Burger
Principal Investigator

Pittsburgh

University of Pittsburgh Cancer Institute (UPCI)

Alexander Babatunde Olawaiye
Ph: 412-647-2811

Alexander Babatunde Olawaiye
Principal Investigator

West Penn Hospital

Thomas Carl Krivak
Ph: 412-578-5000

Thomas Carl Krivak
Principal Investigator

State College

Geisinger Medical Group

Radhika P. Gogoi
Ph: 570-271-5251

Radhika P. Gogoi
Principal Investigator

West Chester

Chester County Hospital

William Emil Luginbuhl
Ph: 610-431-5297

William Emil Luginbuhl
Principal Investigator

Wilkes-Barre

Geisinger Wyoming Valley/Henry Cancer Center

Radhika P. Gogoi
Ph: 570-271-5251

Radhika P. Gogoi
Principal Investigator

York

WellSpan Health-York Hospital

Mark A. Miller
Ph: 877-441-7957

Mark A. Miller
Principal Investigator

Rhode Island
Providence

Women and Infants Hospital

Paul A. DiSilvestro
Ph: 401-274-1122

Paul A. DiSilvestro
Principal Investigator

South Carolina
Charleston

Medical University of South Carolina

Jennifer L. Young Pierce
Ph: 843-792-9321

Jennifer L. Young Pierce
Principal Investigator

Greenwood

Self Regional Healthcare

Jennifer L. Young Pierce
Ph: 843-792-9321

Jennifer L. Young Pierce
Principal Investigator

South Dakota
Sioux Falls

Sanford Cancer Center-Oncology Clinic

Maria Caroline Bell
Ph: 218-333-5000

Maria Caroline Bell
Principal Investigator

Sanford USD Medical Center - Sioux Falls

Maria Caroline Bell
Ph: 218-333-5000

Maria Caroline Bell
Principal Investigator

Tennessee
Chattanooga

Chattanooga's Program in Women's Oncology

Stephen Ernest DePasquale
Ph: 423-266-3636

Stephen Ernest DePasquale
Principal Investigator

Knoxville

University of Tennessee - Knoxville

Larry Clinton Kilgore
Ph: 865-544-9773

Larry Clinton Kilgore
Principal Investigator

Texas
Dallas

Parkland Memorial Hospital

David Scott Miller
Ph: 214-648-7097

David Scott Miller
Principal Investigator

UT Southwestern/Simmons Cancer Center-Dallas

David Scott Miller
Ph: 214-648-7097

David Scott Miller
Principal Investigator

Fort Sam Houston

Brooke Army Medical Center

Jason Cory Barnett
Ph: 210-916-4837

Jason Cory Barnett
Principal Investigator

Houston

M D Anderson Cancer Center

Diane C. Bodurka
Ph: 713-792-3245

Diane C. Bodurka
Principal Investigator

Memorial Hermann Texas Medical Center

Elizabeth Kathleen Nugent
Ph: 713-792-3245

Elizabeth Kathleen Nugent
Principal Investigator

The Methodist Hospital System

Aparna A. Kamat
Ph: 713-790-2700

Aparna A. Kamat
Principal Investigator

Sugar Land

Houston Methodist Sugar Land Hospital

Aparna A. Kamat
Ph: 713-790-2700

Aparna A. Kamat
Principal Investigator

Utah
Salt Lake City

Huntsman Cancer Institute/University of Utah

Theresa Louise Werner
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

Theresa Louise Werner
Principal Investigator

Vermont
Burlington

University of Vermont Medical Center

Cheung Wong
Ph: 802-656-8990

Cheung Wong
Principal Investigator

Virginia
Charlottesville

University of Virginia Cancer Center

Susan Carnall Modesitt
Ph: 434-243-6143

Susan Carnall Modesitt
Principal Investigator

Richmond

Henrico Doctor's Hospital

Weldon E. Chafe
Ph: 804-628-1939

Weldon E. Chafe
Principal Investigator

Virginia Commonwealth University/Massey Cancer Center

Weldon E. Chafe
Ph: 804-628-1939

Weldon E. Chafe
Principal Investigator

Virginia Gynecologic Oncology

Weldon E. Chafe
Ph: 804-628-1939

Weldon E. Chafe
Principal Investigator

Roanoke

Carilion Clinic Gynecological Oncology

Janet L. Osborne
Ph: 540-985-8510

Janet L. Osborne
Principal Investigator

Washington
Auburn

MultiCare Auburn Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Bainbridge Island

Virginia Mason Bainbridge Island Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Bellevue

Overlake Hospital Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Federal Way

Virginia Mason Federal Way Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Gig Harbor

MultiCare Gig Harbor Medical Park

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Gig Harbor

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Kennewick

Northwest Cancer Clinic

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Lynnwood

Virginia Mason Lynnwood Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Poulsbo

Peninsula Cancer Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Puyallup

MultiCare Good Samaritan Hospital

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Puyallup

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Seattle

Virginia Mason CCOP

Amy D. Brockmeyer
Ph: 206-342-6954
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Amy D. Brockmeyer
Principal Investigator

Tacoma

Multicare Health System

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Jackson Hall

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Saint Joe's

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

West Virginia
Morgantown

Monongalia Hospital

Jamie L. Lesnock
Ph: 888-823-5923
Email: ctsucontact@westat.com

Jamie L. Lesnock
Principal Investigator

Wisconsin
Chippewa Falls

Marshfield Clinic-Chippewa Center

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

Eau Claire

Marshfield Clinic Cancer Center at Sacred Heart

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

Green Bay

Aurora BayCare Medical Center

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Green Bay Oncology at Saint Vincent Hospital

Jonathan Edward Tammela
Ph: 920-433-8889

Jonathan Edward Tammela
Principal Investigator

Green Bay Oncology Limited at Saint Mary's Hospital

Jonathan Edward Tammela
Ph: 920-433-8889

Jonathan Edward Tammela
Principal Investigator

Saint Mary's Hospital

Jonathan Edward Tammela
Ph: 920-433-8889

Jonathan Edward Tammela
Principal Investigator

Saint Vincent Hospital

Jonathan Edward Tammela
Ph: 920-433-8889

Jonathan Edward Tammela
Principal Investigator

La Crosse

Gundersen Lutheran Medical Center

Sigurdur Bodvarsson
Ph: 608-775-2385
Email: cancerctr@gundluth.org

Sigurdur Bodvarsson
Principal Investigator

Madison

University of Wisconsin Hospital and Clinics

David M. Kushner
Ph: 877-405-6866

David M. Kushner
Principal Investigator

Manitowoc

Holy Family Memorial Hospital

Jonathan Edward Tammela
Ph: 920-433-8889

Jonathan Edward Tammela
Principal Investigator

Marinette

Bay Area Medical Center

Jonathan Edward Tammela
Ph: 920-433-8889

Jonathan Edward Tammela
Principal Investigator

Marshfield

Marshfield Clinic

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

Milwaukee

Aurora Saint Luke's Medical Center

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Minocqua

Marshfield Clinic-Minocqua Center

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

New Richmond

Cancer Center of Western Wisconsin

Joseph W. Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Joseph W. Leach
Principal Investigator

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Rhinelander

Marshfield Clinic at James Beck Cancer Center

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

Rice Lake

Marshfield Clinic-Rice Lake Center

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

Stevens Point

Marshfield Clinic Cancer Care at Saint Michael's Hospital

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

Wausau

Marshfield Clinic-Wausau Center

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

West Allis

Aurora West Allis Medical Center

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Weston

Marshfield Clinic - Weston Center

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

Wisconsin Rapids

Marshfield Clinic - Wisconsin Rapids Center

Anthony Carroll Evans
Ph: 715-389-4457

Anthony Carroll Evans
Principal Investigator

Wyoming
Cheyenne

Cheyenne Regional Medical Center-West

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Sheridan

Welch Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT00719303

Note: Information about participating sites on pharmaceutical industry trials may be incomplete. Please visit the ClinicalTrials.gov record via the link above for more information about participating sites.