Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer

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Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentActive18 and overNCI, OtherRTOG 0815
CDR0000648194, NCI-2011-01948, NCT00936390

Trial Description

Summary

RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells and shrink tumors. Androgens can cause the growth of prostate cancer cells. Androgen-deprivation therapy may lessen the amount of androgens made by the body. It is not yet known whether radiation therapy is more effective with or without androgen-deprivation therapy in treating patients with prostate cancer.

PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with androgen-deprivation therapy in treating patients with prostate cancer.

Further Study Information

OBJECTIVES:

Primary

  • Demonstrate an overall survival (OS) advantage in patients with intermediate-risk prostate cancer treated with dose-escalated radiotherapy (RT) with versus without short-term androgen-deprivation therapy (ADT).

Secondary

  • Determine whether the addition of ADT to dose-escalated RT versus RT alone improves clinical failures, biochemical failure by the "nadir +2", freedom from failure, rate of salvage ADT, and prostate cancer-specific mortality in these patients.
  • Estimate the magnitude of benefit of ADT with respect to OS in patients treated with different RT modalities (i.e., external-beam radiation therapy alone vs low-dose rate brachytherapy boost vs high-dose rate brachytherapy boost).
  • Compare acute and late treatment adverse events of these regimens and correlate these events with the presence or absence of pre-existing comorbidity as documented by the Adult Comorbidity Evaluation 27 assessment.

OUTLINE: This is a multicenter, dose-escalation study of radiotherapy. Patients are stratified according to number of risk factors (1 vs 2-3), comorbidity (ACE-27 grade ≥ 2 vs < 2), and radiotherapy (RT) modality (dose-escalated external-beam RT [EBRT] vs EBRT and low-dose rate brachytherapy boost vs EBRT and high-dose rate brachytherapy boost). Patients are randomized to 1 of 2 treatment arms.

  • Arm I: Patients undergo EBRT* once daily on days 1-5 for about 9 weeks (44 treatments). Some patients instead receive EBRT with high-dose rate or low-dose rate brachytherapy implant on days 1-5 for about 5 weeks (25 treatments). NOTE: *Type of RT is at discretion of treating physician and may include either 3D-conformal RT or intensity-modulated RT.
  • Arm II: Patients receive androgen-deprivation therapy comprising luteinizing-hormone releasing-hormone (LHRH) agonist (leuprolide, goserelin, buserelin, or triptorelin) subcutaneously or as an injection every 1 to 3 months AND an oral antiandrogen therapy (flutamide 3 times daily or bicalutamide once daily) for 6 months. Beginning 8 weeks after the first LHRH injection, patients undergo radiotherapy as in arm I.

After completion of study therapy, patients are followed up periodically.

Eligibility Criteria

DISEASE CHARACTERISTICS:

  • Histologically confirmed adenocarcinoma of the prostate diagnosed within the past 180 days and at intermediate-risk for recurrence by meeting 1 or more of the following criteria:
  • Gleason score = 7
  • Prostate Specific Antigen (PSA) > 10 and ≤ 20 ng/mL
  • Baseline serum PSA value performed within 60 days with an FDA-approved assay (e.g., Abbott, Hybritech)
  • Baseline PSA must not be obtained during any of the following time frames:10-day period after prostate biopsy, after initiation of androgen-deprivation therapy, or within the past 30 days after discontinuation of finasteride (90 days for dutasteride)
  • Clinical stage T2b or T2c disease
  • Patients previously diagnosed with low-risk (Gleason score < 6, clinical stage < T2a, and PSA < 10 ng/mL) prostate cancer undergoing active surveillance who are re-biopsied and found to have intermediate-risk disease according to the protocol criteria are eligible for enrollment within 6 months of the repeat biopsy procedure
  • Patients with Gleason Score ≥ 8, PSA > 20 ng/mL, OR clinical stage ≥ T3 are ineligible for this trial
  • If findings of extracapsular extension or seminal vesicle invasion are noted on prostate MRI, this study, if used, will not render patients ineligible for accrual to this protocol
  • Primary tumor staging for eligibility purposes is to be based on palpable or core biopsy evidence only with respect to extracapsular extension or seminal vesicle involvement
  • No patients with all 3 intermediate-risk factors who also have ≥ 50% of the number of their biopsy cores positive for cancer
  • The percentage of biopsy cores involved will only be considered with respect to eligibility for those patients with all 3 of the above risk factors (i.e., patients with one or two of the above risk factors are eligible irrespective of the percentage of biopsy cores involved)
  • Clinically negative lymph nodes as established by imaging (pelvic and/or abdominal CT scan or MRI), nodal sampling, or dissection within the past 60 days (required for patients with 2-3 risk factors)
  • Abdominal imaging not required for a single intermediate-risk factor (these studies may be obtained at the discretion of the treating physician)
  • Lymph nodes that are equivocal or questionable by imaging allowed without biopsy if nodes ≤ 1.5 cm
  • Any node > 1.5 cm on imaging requires a negative biopsy
  • No evidence of bone metastases on bone scan within the past 60 days
  • Bone scan not required for patients with a single intermediate-risk factor (scan may be obtained at the discretion of the treating physician)
  • Equivocal bone scan findings allowed if plain film x-rays negative for metastasis

PATIENT CHARACTERISTICS:

  • Zubrod performance status 0-1
  • Absolute neutrophil count (ANC) ≥ 1,800/mm^3*
  • Platelet count ≥ 100,000/mm^3*
  • Hemoglobin ≥ 8.0 g/dL (transfusion or other intervention to achieve level allowed)*
  • NOTE: *For patients undergoing brachytherapy only.
  • Fertile patients must use effective contraception during and for the 3 months after cessation of protocol treatment
  • No invasive malignancy or hematological malignancy (e.g., leukemia, lymphoma, myeloma) within the past 5 years except adequately treated non-melanomatous skin cancer
  • Prior diagnoses of carcinoma in situ allowed
  • No severe or active co-morbidity with any of the following:
  • Unstable angina and/or congestive heart failure requiring hospitalization within the past 6 months
  • Transmural myocardial infarction within the past 6 months
  • Acute bacterial or fungal infection requiring intravenous antibiotics
  • Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy, within the past 30 days
  • Hepatic insufficiency resulting in clinical jaundice and/or coagulation defects
  • Laboratory tests for liver function and coagulation parameters not required for entry into this protocol
  • AIDS based upon current Centers for Disease Control (CDC) definition
  • HIV testing not required for entry into this protocol
  • HIV-seropositive patients who do not meet criteria for diagnosis of AIDS allowed

PRIOR CONCURRENT THERAPY:

  • See Disease Characteristics
  • No prior radical surgery (prostatectomy), high-intensity focused ultrasound, or cryosurgery for prostate cancer
  • No prior hormonal therapy, such as LHRH agonists (e.g., goserelin, leuprolide), antiandrogens (e.g., flutamide, bicalutamide), estrogens (e.g., DES), or bilateral orchiectomy
  • No finasteride within past 30 days (90 days for dutasteride)
  • No prior or concurrent cytotoxic chemotherapy for prostate cancer
  • Prior chemotherapy for a different cancer allowed
  • No prior radiotherapy (RT), including brachytherapy, to the region of the study cancer that would result in overlap of RT fields
  • Patients undergoing brachytherapy must have transrectal ultrasound confirmation of prostate volume < 60 cc, American Urological Association (AUA) score ≤ 15 within the past 60 days of registration, and no history of prior transurethral resection of the prostate (TURP)
  • TURP allowed for patients who receive external-beam radiation therapy only

Trial Contact Information

Trial Lead Organizations/Sponsors

Radiation Therapy Oncology Group

  • National Cancer Institute
  • NRG Oncology
Alvaro A. Martinez, Study Chair

Trial Sites

U.S.A.

Alaska
Fairbanks

Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital

Huong T. Pham
Ph: 206-342-6954
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Arizona
Peoria

Arizona Center for Cancer Care - Peoria

Daniel R Reed
Ph: 623-773-2873

Phoenix

St. Joseph's Hospital and Medical Center

David G. Brachman
Ph: 877-602-4111

Scottsdale

21st Century Oncology - Scottsdale

Karen A Finkelstein
Ph: 505-843-7813

Arizona Oncology Services Foundation

David G. Brachman
Ph: 877-602-4111

Mayo Clinic Scottsdale

Richard (Chunhee) Choo
Ph: 507-538-7623

Tucson

Arizona Oncology - Tucson

Vivek S Kavadi
Ph: 281-277-5200

California
Berkeley

Alta Bates Summit Comprehensive Cancer Center

Christopher Jones
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Burbank

Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center

Matthew C Solhjem
Ph: 503-215-6412
Email: Julie.Cramer@providence.org

Chico

Enloe Cancer Center at Enloe Medical Center

Grace E Yuh
Ph: 530-332-3808

El Segundo

21st Century Oncology - El Segundo

David Khan
Ph: 888-326-9729

Fresno

Fresno Cancer Center

Louis Fehrenbacher
Ph: 626-564-3455

Greenbrae

Marin Cancer Institute at Marin General Hospital

Lloyd T Miyawaki
Ph: 415-925-7325

Long Beach

Veterans Affairs Medical Center - Long Beach

Samar H. Azawi
Ph: 562-826-8000

Los Angeles

USC/Norris Comprehensive Cancer Center and Hospital

Leslie Ballas
Ph: 323-865-0451

Leslie Ballas
Ph: 323-865-0451

Oakland

Kaiser Permanente-Oakland

Louis Fehrenbacher
Ph: 626-564-3455

Palm Springs

Desert Regional Medical Center Comprehensive Cancer Center

Amir Lavaf
Ph: 760-416-4730

Palo Alto

Stanford Cancer Center

Mark K Buyyounouski
Ph: 650-498-7061
Email: ccto-office@stanford.edu

Pomona

Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center

Yallapragada S. Rao
Ph: 909-865-9555

Rancho Cardova

Kaiser Permanente Medical Center - Rancho Cordova

Louis Fehrenbacher
Ph: 626-564-3455

Rohnert Park

Rohnert Park Cancer Center

Louis Fehrenbacher
Ph: 626-564-3455

Roseville

The Permanente Medical Group-Roseville Radiation Oncology

Louis Fehrenbacher
Ph: 626-564-3455

Sacramento

South Sacramento Cancer Center

Louis Fehrenbacher
Ph: 626-564-3455

University of California Davis Cancer Center

Richard K. Valicenti
Ph: 916-734-3089

San Diego

Rebecca and John Moores UCSD Cancer Center

Loren K Mell
Ph: 858-822-5354
Email: cancercto@ucsd.edu

San Francisco

California Pacific Medical Center - California Campus

Christopher Jones
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

UCSF Helen Diller Family Comprehensive Cancer Center

I-Chow J Hsu
Ph: 877-827-3222

Santa Clara

Kaiser Permanente Medical Center - Santa Clara Homestead Campus

Louis Fehrenbacher
Ph: 626-564-3455

South San Francisco

Kaiser Permanente Cancer Treatment Center

Louis Fehrenbacher
Ph: 626-564-3455

Truckee

Tahoe Forest Cancer Center

Richard K. Valicenti
Ph: 916-734-3089

Vallejo

Sutter Solano Medical Center

Christopher Jones
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Colorado
Aurora

University of Colorado Cancer Center at UC Health Sciences Center

David Raben
Ph: 720-848-0650

Fort Collins

Poudre Valley Hospital

Joshua H Petit
Ph: 970-482-3328

Connecticut
Hartford

Helen and Harry Gray Cancer Center at Hartford Hospital

Neal B Goldberg
Ph: 860-224-5660

Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

Samir Narayan
Ph: 734-712-4673

Hew Haven

Father Michael J. McGivney Center for Cancer Care at Hospital of Saint Raphael

Joseph G. Cardinale
Ph: 203-789-3545

Meriden

MidState Medical Center

Neal B Goldberg
Ph: 860-224-5660

New Britain

George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus

Neal B Goldberg
Ph: 860-224-5660

Delaware
Newark

Helen F. Graham Cancer Center at Christiana Hospital

Adam Raben
Ph: 302-733-6227

Adam Raben
Ph: 302-733-6227

Florida
Deerfield Beach

University of Miami/Deerfield Beach

Alan Pollack
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Fort Lauderdale

Broward General Medical Center Cancer Center

Evan M Landau
Ph: 954-355-5346

Jacksonville

Mayo Clinic - Jacksonville

Richard (Chunhee) Choo
Ph: 507-538-7623

Kissimmee

Florida Hospital Kissimmee

Lee M. Zehngebot
Ph: 407-303-5623

Lakeland

Center for Cancer Care and Research at Watson Clinic, LLP

John T Barrett
Ph: 863-680-7780

Miami

Jackson Memorial Hospital

Alan Pollack
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

South Miami Hospital

Maria-Amelia M Rodrigues
Ph: 888-823-5923
Email: ctsucontact@westat.com

University of Miami Sylvester Comprehensive Cancer Center - Miami

Alan Pollack
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Orlando

Florida Hospital Cancer Institute at Florida Hospital Orlando

Lee M. Zehngebot
Ph: 407-303-5623

Georgia
Atlanta

Georgia Cancer Center for Excellence at Grady Memorial Hospital

Ashesh B. Jani
Ph: 404-778-1868

Piedmont Hospital

Adam W Nowlan
Ph: 404-425-7943
Email: ORS@piedmont.org

Winship Cancer Institute of Emory University

Scott Edelman
Ph: 404-321-6111ext7632

Columbus

John B. Amos Cancer Center

Douglas F. Ciuba
Ph: 706-660-6404

Decatur

Veterans Affairs Medical Center - Atlanta (Decatur)

Scott Edelman
Ph: 404-321-6111ext7632

Gainesville

Northeast Georgia Medical Center

Frank G. Lake
Ph: 770-219-8800
Email: cancerpatient.navigator@nghs.com

Savannah

Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center

Aaron W Pederson
Ph: 912-350-8568

Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler

Howard A. Zaren
Ph: 800-622-6877

Hawaii
Honolulu

Cancer Research Center of Hawaii

Paul A. DeMare
Ph: 808-545-8548

Hawaii Medical Center - East

Paul A. DeMare
Ph: 808-545-8548

Queen's Cancer Institute at Queen's Medical Center

Paul A. DeMare
Ph: 808-545-8548

Idaho
Boise

Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

Samir Narayan
Ph: 734-712-4673

Post Falls

Kootenai Cancer Center - Post Falls

Benjamin Thomas Marchello
Ph: 800-648-6274

Illinois
Carbondale

Memorial Hospital of Carbondale

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Chicago

Creticos Cancer Center at Advocate Illinois Masonic Medical Center

Santosh V Yajnik
Ph: 773-296-5360

John H. Stroger, Jr. Hospital of Cook County

Thomas E. Lad
Ph: 312-864-6000

University of Chicago Cancer Research Center

Stanley L Liauw
Ph: 773-834-7424

Decatur

Decatur Memorial Hospital Cancer Care Institute

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Effingham

Crossroads Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Hines

Veterans Affairs Medical Center - Hines

William Small
Ph: 708-226-4357

Maywood

Cardinal Bernardin Cancer Center at Loyola University Medical Center

Matthew M Harkenrider
Ph: 708-226-4357

Pekin

Cancer Treatment Center at Pekin Hospital

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Peoria

OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC

Nguyet A Le-Lindqwister
Ph: 800-793-2262

OSF St. Francis Medical Center

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Rockford

Advanced Care and Treatment Medical Group, PC

Harvey Eric Einhorn
Ph: 779-696-9400
Email: cancercare@swedishamerican.org

Springfield

Cancer Institute at St. John's Hospital

Laurent Brard
Ph: 217-525-5666
Email: diana.weyhenmeyer@st-johns.org

Regional Cancer Center at Memorial Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Indiana
Anderson

Saint John's Health System

Alexander M. Yeh
Ph: 765-646-8358

Avon

Clarian West Medical Center

Mark P Langer
Ph: 317-274-2552

Fort Wayne

Parkview Regional Cancer Center at Parkview Health

Brian K Chang
Ph: 260-373-8888
Email: parkviewresearch@parkview.com

Radiation Oncology Associates Southwest

Brian K Chang
Ph: 260-373-8888
Email: parkviewresearch@parkview.com

Indianapolis

Indiana University Melvin and Bren Simon Cancer Center

Mark P Langer
Ph: 317-274-2552

Methodist Cancer Center at Methodist Hospital

Mark P Langer
Ph: 317-274-2552

Iowa
Ames

McFarland Clinic, PC

Joseph James Merchant
Ph: 515-239-2621

Dubuque

Wendt Regional Cancer Center at Finley Hospital

Nagendra (Bobby) S Koneru
Ph: 800-397-2467

Kentucky
Lexington

Central Baptist Hospital

Alan Beckman
Ph: 859-260-6425

Owensboro

Mitchell Memorial Cancer Center at Owensboro Medical Health System

Samuel R Faught
Ph: 270-688-3691
Email: shawns@omhs.org

Louisiana
Baton Rouge

Mary Bird Perkins Cancer Center - Baton Rouge

Augusto C Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

New Orleans

Ochsner Cancer Institute at Ochsner Clinic Foundation

Troy G. Scroggins
Ph: 888-562-4763

Tulane Cancer Center at Tulane University Hospital and Clinic

William R. Robinson
Ph: 504-988-6121

Maine
Lewiston

Central Maine Comprehensive Cancer Center at Central Maine Medical Center

Courtney A Jensen
Ph: 207-795-8250
Email: benderli@cmhc.org

Scarborough

Maine Medical Center- Scarborough Campus

Ian J Bristol
Ph: 207-396-8090
Email: wrighd@mmc.org

Maryland
Annapolis

DeCesaris Cancer Institute at Anne Arundel Medical Center

Angel E. Torano
Ph: 443-481-1320
Email: kbodenhorn@aahs.org

Baltimore

Greenebaum Cancer Center at University of Maryland Medical Center

Young Kwok
Ph: 800-888-8823

St. Agnes Hospital Cancer Center

Richard S. Hudes
Ph: 410-368-2910

Bel Air

Upper Chesapeake Medical Center

Young Kwok
Ph: 800-888-8823

Bethesda

National Naval Medical Center

Christopher N Premo
Ph: 301-319-2100

Columbia

Central Maryland Oncology Center

Young Kwok
Ph: 800-888-8823

Glen Burnie

Tate Cancer Center at Baltimore Washington Medical Center

Young Kwok
Ph: 800-888-8823

Silver Spring

Holy Cross Hospital

Daniel H Clarke
Ph: 310-754-7552

Massachusetts
Boston

Boston University Cancer Research Center

Ariel E Hirsch
Ph: 617-638-8265

Massachusetts General Hospital

Jason A Efstathiou
Ph: 877-726-5130

Danvers

NSMC Cancer Center - Peabody

Jason A Efstathiou
Ph: 877-726-5130

Fall River

Hudner Oncology Center at Saint Anne's Hospital - Fall River

Michele Albert
Ph: 508-674-5600ext2515

Hyannis

Davenport-Mugar Cancer Center at Cape Cod Hospital

Daniel J Canaday
Ph: 508-862-5799

Lowell

Lowell General Hospital

Jason A Efstathiou
Ph: 877-726-5130

Pittsfield

Berkshire Hematology Oncology, PC

Harvey Zimbler
Ph: 413-496-8205
Email: ggero@bhs1.org

Plymouth

Jordan Hospital Club Cancer Center

James M Koomey
Ph: 508-830-2390
Email: cancerinfo@jordanhospital.org

Springfield

Baystate Medical Center

Seth A Kaufman
Ph: 413-794-9338

Worcester

Saint Vincent Hospital - Fallon Clinic

William B Casey
Ph: 508-363-7018

Michigan
Ann Arbor

Saint Joseph Mercy Cancer Center

Samir Narayan
Ph: 734-712-4673

University of Michigan Comprehensive Cancer Center

Alvaro Martinez
Email: alvaro.martinez@rtsx.com

Battle Creek

Battle Creek Health System Cancer Care Center

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Bay City

Bay Regional Medical Center

Hesham E. Gayar
Ph: 810-342-4071

Clinton Township

Henry Ford Macomb Hospital

Eleanor M. Walker
Ph: 313-916-1784

Detroit

Josephine Ford Cancer Center at Henry Ford Hospital

Eleanor M. Walker
Ph: 313-916-1784

Van Elslander Cancer Center at St. John Hospital and Medical Center

Samir Narayan
Ph: 734-712-4673

Farmington Hills

21st Century Oncology-Farmington Hills

Jeffrey D. Forman
Ph: 248-858-6215

Flint

Genesys Hurley Cancer Institute

Samir Narayan
Ph: 734-712-4673

McLaren Cancer Institute

Hesham E. Gayar
Ph: 810-342-4071

Grand Rapids

Butterworth Hospital at Spectrum Health

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Lacks Cancer Center at Saint Mary's Health Care

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Kalamazoo

West Michigan Cancer Center

Sunil Nagpal
Ph: 269-373-7458

Lansing

Sparrow Regional Cancer Center

Samir Narayan
Ph: 734-712-4673

Lapeer

Great Lakes Cancer Institute - Lapeer Campus

Hesham E. Gayar
Ph: 810-342-4071

Mount Clemens

Clemens Regional Medical Center

Hesham E. Gayar
Ph: 810-342-4071

Mount Pleasant

Norval K. Morey Cancer Center at Central Michigan Community Hospital

Hesham E. Gayar
Ph: 810-342-4071

Muskegon

Mercy General Health Partners

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Owosso

Great Lakes Cancer Institute - Owosso

Hesham E. Gayar
Ph: 810-342-4071

Petoskey

Northern Michigan Hospital

Hesham E. Gayar
Ph: 810-342-4071

Pontiac

St. Joseph Mercy Oakland

Samir Narayan
Ph: 734-712-4673

Port Huron

Mercy Regional Cancer Center at Mercy Hospital

Samir Narayan
Ph: 734-712-4673

Royal Oak

William Beaumont Hospital - Royal Oak Campus

Daniel J Krauss
Ph: 248-551-7695

Saginaw

Seton Cancer Institute at Saint Mary's - Saginaw

Samir Narayan
Ph: 734-712-4673

Trenton

Down River Center for Oncology

Eleanor M. Walker
Ph: 313-916-1784

Troy

21st Century Oncology-Troy

Jeffrey D. Forman
Ph: 248-858-6215

William Beaumont Hospital - Troy Campus

Daniel J Krauss
Ph: 248-551-7695

Warren

St. John Macomb Hospital

Samir Narayan
Ph: 734-712-4673

West Bloomfield

Henry Ford Medical Center - West Bloomfield

Eleanor M. Walker
Ph: 313-916-1784

Minnesota
Bemidji

MeritCare Bemidji

Preston D. Steen
Ph: 701-234-6161

Duluth

Miller - Dwan Medical Center

Daniel Nikcevich
Ph: 888-203-7267

St. Luke's Hospital Cancer Care Center

Steven R Bonin
Ph: 888-823-5923
Email: ctsucontact@westat.com

Edina

Fairview Southdale Hospital

Paul Sperduto
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Saint Paul

Regions Hospital Cancer Care Center

Paul Sperduto
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Missouri
Joplin

St. John's Regional Medical Center

Jay W Carlson
Ph: 800-821-7532

Rolla

Phelps County Regional Medical Center

Jay W Carlson
Ph: 800-821-7532

Saint Louis

Barnes-Jewish West County Hospital

Jeff M. Michalski
Ph: 800-600-3606
Email: info@siteman.wustl.edu

David C. Pratt Cancer Center at St. John's Mercy

Jay W Carlson
Ph: 800-821-7532

Missouri Baptist Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

Jeff M. Michalski
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Saint Peters

Siteman Cancer Center at Barnes-Jewish St. Peters Hospital - St. Peters

Jeff M. Michalski
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Springfield

Hulston Cancer Center at Cox Medical Center South

Jay W Carlson
Ph: 800-821-7532

St. John's Regional Health Center

Jay W Carlson
Ph: 800-821-7532

Montana
Billings

Billings Clinic Cancer Center - 801 N 29th Street

Benjamin Thomas Marchello
Ph: 800-648-6274

Nebraska
Lincoln

Southeast Nebraska Hematology Oncology Consultants at Southeast Nebraska Cancer Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Omaha

Fred and Pamela Buffett Cancer Center

Andrew O Wahl
Ph: 402-559-6941
Email: unmcrsa@unmc.edu

Methodist Estabrook Cancer Center

Tien-Shew W Huang
Ph: 402-354-5144

New Hampshire
Concord

Payson Center for Cancer Care at Concord Hospital

Su K Metcalfe
Ph: 800-441-1138

Exeter

Center for Cancer Care at Exeter Hospital

Gary Miller Proulx
Ph: 800-439-3837

Keene

Kingsbury Center for Cancer Care at Cheshire Medical Center

Alan C. Hartford
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Lebanon

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center

Alan C. Hartford
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Manchester

Elliot Regional Cancer Center at Elliot Hospital

Brian R Knab
Ph: 603-663-1800

New Jersey
Brick

Ocean Medical Center at Meridian Health

Douglas A Miller
Ph: 732-206-8384

Camden

Cancer Institute of New Jersey at Cooper University Hospital - Camden

Ashraf F Youssef
Ph: 856-325-6757

East Orange

Veterans Affairs Medical Center - East Orange

Maria D. Kelly
Ph: 800-475-2336
Email: patricia.goyer@med.va.gov

Mount Holly

Virtua Fox Chase Health Cancer Program at Virtua Memorial Hospital Burlington County

Lemuel S. Ariaratnam
Ph: 888-847-8823

Neptune

Jersey Shore Cancer Center at Jersey Shore University Medical Center

Douglas A Miller
Ph: 732-206-8384

Red Bank

Booker Cancer Center at Riverview Medical Center

Douglas A Miller
Ph: 732-206-8384

Sparta

Frederick R. and Betty M. Smith Cancer Treatment Center

Maria Werner-Wasik
Ph: 215-955-6084

Toms River

J. Phillip Citta Regional Cancer Center at Community Medical Center

David J D'Ambrosio
Ph: 732-818-3882

Voorhees

Cancer Institute of New Jersey at Cooper - Voorhees

Ashraf F Youssef
Ph: 856-325-6757

West Orange

Prostate Cancer Center of New Jersey

Robert Ivker
Ph: 888-823-5923
Email: ctsucontact@westat.com

New Mexico
Albuquerque

University of New Mexico Cancer Center

Benny J. Liem
Ph: 505-272-6972

Alvaro Martinez
Email: alvaro.martinez@rtsx.com

Las Cruces

Memorial Medical Center

Benny J. Liem
Ph: 505-272-6972

New York
Bay Shore

Southside Hospital

Louis Potters
Ph: 516-562-3467

Binghamton

Lourdes Regional Cancer Center

Michael Fallon
Ph: 607-798-5230

Canandiaqua

Sands Cancer Center

Yuhchyau Chen
Ph: 585-275-5830

Cooperstown

Bassett Healthcare Regional Cancer Program at Mary Imogene Bassett Hospital

Naoyuki G Saito
Ph: 607-547-3073
Email: diana.crean@bassett.org

Elmira

Falck Cancer Center at Arnot Ogden Medical Center

Chi K Tsang
Ph: 607-271-7000

New Hyde Park

Long Island Jewish Medical Center

Louis Potters
Ph: 516-562-3467

Monter Cancer Center of the North Shore-LIJ Health System

Louis Potters
Ph: 516-562-3467

New York

Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center

Israel Deutsch
Ph: 212-305-8615

Poughkeepsie

Hudson Valley Oncology Associates

Maria Werner-Wasik
Ph: 215-955-6084

Rochester

Daisy Marquis Jones Radiation Oncology Center at Highland Hospital of Rochester

Yuhchyau Chen
Ph: 585-275-5830

James P. Wilmot Cancer Center at University of Rochester Medical Center

Yuhchyau Chen
Ph: 585-275-5830

University Radiation Oncology at Parkridge Hospital

Yuhchyau Chen
Ph: 585-275-5830

North Carolina
Durham

Duke Cancer Institute

W. Robert Lee
Ph: 888-275-3853

Morehead City

Coleman Radiation Oncology Center at Carter General Hospital

Michael A Papagikos
Ph: 910-251-1839

New Bern

CarolinaEast Cancer Care

Michael A Papagikos
Ph: 910-251-1839

Raleigh

Rex Cancer Center at Rex Hospital

Nathan C Sheets
Ph: 919-784-7209

Supply

South Atlantic Radiation Oncology, LLC

Michael A Papagikos
Ph: 910-251-1839

Wilmington

Coastal Carolina Radiation Oncology Center

Michael A Papagikos
Ph: 910-251-1839

North Dakota
Bismarck

Medcenter One Hospital Cancer Care Center

Preston D. Steen
Ph: 701-234-6161

Fargo

Roger Maris Cancer Center at MeritCare Hospital

Preston D. Steen
Ph: 701-234-6161

Minot

Trinity CancerCare Center

Kevin Basil Collins
Ph: 888-823-5923
Email: ctsucontact@westat.com

Ohio
Akron

McDowell Cancer Center at Akron General Medical Center

Mitchell Lee Fromm
Ph: 330-344-6348

Summa Center for Cancer Care at Akron City Hospital

Charles A Kunos
Ph: 330-375-6101

Barberton

Barberton Citizens Hospital

Charles A Kunos
Ph: 330-375-6101

Beachwood

UHHS Chagrin Highlands Medical Center

Rodney J Ellis
Ph: 800-641-2422

Chardon

Geauga Regional Hospital

Rodney J Ellis
Ph: 800-641-2422

Chillicothe

Adena Regional Medical Center

J. Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

Cincinnati

University of Cincinnati

Kevin P. Redmond
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Cleveland

Case Comprehensive Cancer Center

Rodney J Ellis
Ph: 800-641-2422

Columbus

Riverside Methodist Hospital Cancer Care

J. Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

Zangmeister Center

J. Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

Elyria

Mercy Cancer Center - Elyria

Rodney J Ellis
Ph: 800-641-2422

Maumee

Northwest Ohio Oncology Center

Rex B Mowat
Ph: 800-444-3561

Medina

Summa Health Center at Lake Medina

Charles A Kunos
Ph: 330-375-6101

Mentor

Lake/University Ireland Cancer Center

Rodney J Ellis
Ph: 800-641-2422

Middleburg Heights

Southwest General Health Center

Rodney J Ellis
Ph: 800-641-2422

Oregon

St. Charles Mercy Hospital

Rex B Mowat
Ph: 800-444-3561

Parma

Parma Community General Hospital

Rodney J Ellis
Ph: 800-641-2422

Portsmouth

Southern Ohio Medical Center Cancer Center

Alvaro Martinez
Email: alvaro.martinez@rtsx.com

Ravenna

Robinson Radiation Oncology

Mitchell Lee Fromm
Ph: 330-344-6348

Sandusky

University Hospitals Ireland Cancer Center at Firelands Regional Medical Center

Rodney J Ellis
Ph: 800-641-2422

Sylvania

Flower Hospital Cancer Center

Jeffrey H Muler
Ph: 419-824-1842

Toledo

St. Anne Mercy Hospital

Rex B Mowat
Ph: 800-444-3561

University of Toledo Medical Center

Rex B Mowat
Ph: 800-444-3561

West Chester

University Pointe

Kevin P. Redmond
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Westlake

UHHS Westlake Medical Center

Rodney J Ellis
Ph: 800-641-2422

Oklahoma
Oklahoma City

Stephenson Cancer Center at the University of Oklahoma

Terence S. Herman
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Oregon
Clackamas

Clackamas Radiation Oncology Center

Matthew C Solhjem
Ph: 503-215-6412
Email: Julie.Cramer@providence.org

Eugene

Willamette Valley Cancer Center - Eugene

Vivek S Kavadi
Ph: 281-277-5200

Grants Pass

Three Rivers Community Hospital

Gordon L. Metz
Ph: 541-789-6176

Gresham

Legacy Mount Hood Medical Center

Andrew Y Kee
Ph: 507-538-7623

Medford

Dubs Cancer Center at Rogue Valley Medical Center

Gordon L. Metz
Ph: 541-789-6176

Providence Cancer Center at PMCC

Gordon L. Metz
Ph: 541-789-6176

Portland

Legacy Good Samaritan Hospital & Comprehensive Cancer Center

Andrew Y Kee
Ph: 507-538-7623

Providence Cancer Center at Providence Portland Medical Center

Matthew C Solhjem
Ph: 503-215-6412
Email: Julie.Cramer@providence.org

Providence St. Vincent Medical Center

Matthew C Solhjem
Ph: 503-215-6412
Email: Julie.Cramer@providence.org

Pennsylvania
Abington

Rosenfeld Cancer Center at Abington Memorial Hospital

Wayne H Pinover
Ph: 215-481-2402

Bethlehem

St. Luke's Cancer Network at St. Luke's Hospital

Nimisha Deb
Ph: 610-954-3582
Email: infolink@slhn.org

Danville

Geisinger Cancer Institute at Geisinger Health

Thomas J Gergel
Ph: 570-271-5251

Darby

Mercy Fitzgerald Hospital

Maria Werner-Wasik
Ph: 215-955-6084

Drexel Hill

Delaware County Regional Cancer Center at Delaware County Memorial Hospital

Rachelle M. Lanciano
Ph: 610-284-8237
Email: jolene.garney@crozer.org

Dunmore

Northeast Radiation Oncology Center

Maria Werner-Wasik
Ph: 215-955-6084

Erie

Regional Cancer Center - Erie

Andrew T Figura
Ph: 814-838-0448
Email: mhaynes@trcc.org

Gettysburg

Adams Cancer Center

Amit B. Shah
Ph: 877-441-7957

Hanover

Cherry Tree Cancer Center

Amit B. Shah
Ph: 877-441-7957

Hershey

Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center

Justin J Juliano
Ph: 518-489-3612
Email: gerryann.currier@usoncology.com

Milford

Upper Delaware Valley Cancer Center

Maria Werner-Wasik
Ph: 215-955-6084

Philadelphia

Albert Einstein Cancer Center

Kenneth L. Zeitzer
Ph: 215-456-3880

Fox Chase Cancer Center - Philadelphia

Eric Horwitz
Ph: 215-728-4790

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia

Maria Werner-Wasik
Ph: 215-955-6084

Radiation Therapy Oncology Group

Alvaro Martinez
Ph: 248-553-0606
Email: Alvaro.Martinez@rtsx.com

Pittsburgh

Veterans Affairs Medical Center - Pittsburgh

Kristina Gerszten
Ph: 412-688-6104

West Reading

McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

Michael L Haas
Ph: 610-988-9323

York

WellSpan Health

Amit B. Shah
Ph: 877-441-7957

South Carolina
Anderson

AnMed Cancer Center

Patricia C Griffin
Ph: 800-486-5941

Charleston

Hollings Cancer Center at Medical University of South Carolina

David T Marshall
Ph: 843-792-9321

Greenville

Cancer Centers of the Carolinas - Faris Road

Jeffrey Kent Giguere
Ph: 864-241-6251

CCOP - Greenville

Jeffrey Kent Giguere
Ph: 864-241-6251

Greenwood

Self Regional Cancer Center at Self Regional Medical Center

David T Marshall
Ph: 843-792-9321

Greer

Cancer Centers of the Carolinas - Greer Radiation Oncology

Jeffrey Kent Giguere
Ph: 864-241-6251

Gibbs Cancer Center-Pelham

Patricia C Griffin
Ph: 800-486-5941

Myrtle Beach

Carolina Regional Cancer Center

Patrick M Francke
Ph: 877-460-2657

Seneca

Cancer Centers of the Carolinas - Seneca

Jeffrey Kent Giguere
Ph: 864-241-6251

Spartanburg

Cancer Centers of the Carolinas - Spartanburg

Jeffrey Kent Giguere
Ph: 864-241-6251

Gibbs Regional Cancer Center at Spartanburg Regional Medical Center

Patricia C Griffin
Ph: 800-486-5941

South Dakota
Rapid City

Rapid City Regional Hospital

Michael J Swartz
Ph: 605-716-3982
Email: research@rcrh.org

Tennessee
Knoxville

Thompson Cancer Survival Center

Daniel D Scaperoth
Ph: 865-541-1812

Texas
Austin

Texas Oncology - Midtown Austin

Vivek S Kavadi
Ph: 281-277-5200

Texas Oncology, PA at South Austin Cancer Center

Vivek S Kavadi
Ph: 281-277-5200

Texas Oncology, PA at Texas Oncology Cancer Center - Central

Vivek S Kavadi
Ph: 281-277-5200

Bedford

Texas Oncology, PA at Harris Center HEB

Vivek S Kavadi
Ph: 281-277-5200

Dallas

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas

David A. Pistenmaa
Ph: 214-648-7097

Denton

Texas Oncology, PA at Texas Cancer Center - Denton South

Vivek S Kavadi
Ph: 281-277-5200

Fort Sam Houston

Brooke Army Medical Center

Michael Dullea
Ph: 210-916-4837

Fort Worth

Klabzuba Cancer Center at Harris Methodist Fort Worth Hospital

Vivek S Kavadi
Ph: 281-277-5200

Galveston

University of Texas Medical Branch

Martin Colman
Ph: 409-772-1950
Email: clinical.research@utmb.edu

Houston

Memorial Hermann Hospital - Memorial City

Vivek S Kavadi
Ph: 281-277-5200

Univeristy of Texas M.D. Anderson Cancer Center

Thomas J Pugh
Ph: 713-792-3245

League City

UTMB Cancer Center at Victory Lakes

Martin Colman
Ph: 409-772-1950
Email: clinical.research@utmb.edu

Longview

Longview Cancer Center

Vivek S Kavadi
Ph: 281-277-5200

Round Rock

Texas Oncology, PA - Seton Williamson

Vivek S Kavadi
Ph: 281-277-5200

Texas Oncology, PA at Texas Cancer Center Round Rock

Vivek S Kavadi
Ph: 281-277-5200

Sherman

Texas Oncology, PA at Texas Cancer Center - Sherman

Vivek S Kavadi
Ph: 281-277-5200

Sugar Land

Texas Oncology, PA at Texas Oncology Cancer Center Sugar Land

Vivek S Kavadi
Ph: 281-277-5200

Utah
Murray

Jon and Karen Huntsman Cancer Center at Intermountain Medical Center

R. Jeffrey Lee
Ph: 801-507-3950

Ogden

Val and Ann Browning Cancer Center at McKay-Dee Hospital Center

R. Jeffrey Lee
Ph: 801-507-3950

Saint George

Dixie Regional Medical Center - East Campus

R. Jeffrey Lee
Ph: 801-507-3950

Salt Lake City

Huntsman Cancer Institute at University of Utah

Jonathan D Tward
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

LDS Hospital

R. Jeffrey Lee
Ph: 801-507-3950

Utah Cancer Specialists at UCS Cancer Center

R. Jeffrey Lee
Ph: 801-507-3950

Vermont
Bennington

Southwestern Vermont Regional Cancer Center

Alan C. Hartford
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Rutland

Community Cancer Center at Rutland Regional Medical Center

Richard D. Lovett
Ph: 802-775-7111

Saint Johnsbury

Norris Cotton Cancer Center - North

Alan C. Hartford
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Virginia
Alexandria

INOVA Alexandria Hospital

Jane Grayson
Ph: 703-776-2580
Email: research@inova.org

Fishersville

Augusta Medical Center Cancer Center

Robert M Kyler
Ph: 540-689-7000

Hampton

Sentara Cancer Institute at Sentara CarePlex Hospital

Mark E Shaves
Ph: 757-388-2406

Harrisonburg

RMH Regional Cancer Center at Rockingham Memorial Hospital

Heather Anne W Morgan
Ph: 540-689-7000

Norfolk

Sentara Cancer Institute at Sentara Norfolk General Hospital

Mark E Shaves
Ph: 757-388-2406

Portsmouth

Naval Medical Center - Portsmouth

Edward F Miles
Ph: 757-953-5939

Roanoke

Blue Ridge Cancer Care - Roanoke

Vivek S Kavadi
Ph: 281-277-5200

Virginia Beach

Coastal Cancer Center at Sentara Virginia Beach General Hospital

Mark E Shaves
Ph: 757-388-2406

Washington
Bellingham

St. Joseph Cancer Center

Michael Andre Taylor
Ph: 360-788-8223
Email: cpatz@peacehealth.org

Federal Way

St. Francis Hospital

Huong T. Pham
Ph: 206-342-6954
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Seattle

CCOP - Virginia Mason Research Center

Huong T. Pham
Ph: 206-342-6954
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Virginia Mason Medical Center

Huong T. Pham
Ph: 206-342-6954
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Vancouver

Legacy Salmon Creek Medical Center

Andrew Y Kee
Ph: 507-538-7623

Northwest Cancer Specialists at Vancouver Cancer Center

Vivek S Kavadi
Ph: 281-277-5200

Southwest Washington Medical Center Cancer Center

Matthew C Solhjem
Ph: 503-215-6412
Email: Julie.Cramer@providence.org

Wisconsin
Appleton

Fox Valley Surgical Associates at Appleton Medical Center

Michael E Ray
Ph: 920-380-1500

Green Bay

Bellin Memorial Hospital

Charlie C Pan
Ph: 920-435-8326

St. Mary's Hospital Medical Center - Green Bay

James L Leenstra
Ph: 920-433-8889

St. Vincent Hospital Regional Cancer Center

James L Leenstra
Ph: 920-433-8889

Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center

Mitchell H. Pincus
Ph: 800-252-2990

Johnson Creek

UW Cancer Center Johnson Creek

Gregory M. Cooley
Ph: 920-699-3500
Email: lynda.persico@uwmf.wisc.edu

La Crosse

Franciscan Skemp Healthcare - La Crosse Campus

David J Schwartz
Ph: 608-392-9462

Gundersen Lutheran Center for Cancer and Blood

Collin D Driscoll
Ph: 608-775-2385
Email: cancerctr@gundluth.org

Marinette

Bay Area Cancer Care Center at Bay Area Medical Center

James L Leenstra
Ph: 920-433-8889

Vince Lombardi Cancer Clinic - Marinette

Mitchell H. Pincus
Ph: 800-252-2990

Menomonee Falls

Community Memorial Hospital Cancer Care Center

Colleen A. Lawton
Ph: 414-805-4380

Mequon

Columbia Saint Mary's Hospital - Ozaukee

Craig A Schulz
Ph: 414-326-2675
Email: clinicaltrials@columbia-stmarys.org

Milwaukee

Columbia-Saint Mary's Cancer Care Center

Craig A Schulz
Ph: 414-326-2675
Email: clinicaltrials@columbia-stmarys.org

Froedtert Hospital and Medical College of Wisconsin

Colleen A. Lawton
Ph: 414-805-4380

Veterans Affairs Medical Center - Milwaukee

Elizabeth M. Gore
Ph: 414-805-4380

Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center

Mitchell H. Pincus
Ph: 800-252-2990

Racine

All Saints Cancer Center at Wheaton Franciscan Healthcare

James H. Taylor
Ph: 414-874-4541
Email: Kelli.holton@wfhc.org

Sturgeon Bay

Door County Cancer Center at Door County Memorial Hospital

James L Leenstra
Ph: 920-433-8889

Summit

Aurora Medical Center

Mitchell H. Pincus
Ph: 800-252-2990

West Allis

Aurora Women's Pavilion of West Allis Memorial Hospital

Mitchell H. Pincus
Ph: 800-252-2990

West Bend

Alyce and Elmore Kraemer Cancer Care Center at St. Joseph's Hospital

Colleen A. Lawton
Ph: 414-805-4380

Wisconsin Rapids

Riverview UW Cancer Center at Riverview Hospital

Gregory M. Cooley
Ph: 920-699-3500
Email: lynda.persico@uwmf.wisc.edu

Canada

Alberta
Calgary

Tom Baker Cancer Centre - Calgary

Steve J Angyalfi
Ph: 403-521-3433

Edmonton

Cross Cancer Institute at University of Alberta

Nawaid Usmani
Ph: 780-432-8500

New Brunswick
Saint John

Saint John Regional Hospital

Holly Campbell
Ph: 506-648-6890

Nova Scotia
Halifax

Nova Scotia Cancer Centre

Derek R Wilke
Ph: 902-473-6000

Ontario
Hamilton

Margaret and Charles Juravinski Cancer Centre

Ian S Dayes
Ph: 905-387-9495

London

London Regional Cancer Program at London Health Sciences Centre

David P. D'Souza
Ph: 519-685-8600

Ottawa

Ottawa Hospital Regional Cancer Centre - General Campus

Gad A Perry
Ph: 613-761-4395
Email: info@ohri.ca

Thunder Bay

Cancer Care Program at Thunder Bay Regional Health Sciences

Sunil Premial P Gulavita
Ph: 877-696-7223
Email: cancercareinfo@tbh.net

Toronto

Odette Cancer Centre at Sunnybrook

Gerard Morton
Ph: 416-480-5000

Quebec
Montreal

Maisonneuve-Rosemont Hospital

Peter Vavassis
Ph: 514-252-3400ext3329

McGill Cancer Centre at McGill University

Fabio L Cury
Ph: 514-398-1444
Email: penny.chipman@mcgill.ca

Quebec City

Centre Hospitalier Universitaire de Quebec

Eric Vigneault
Ph: 418-525-4444

Sherbrooke

CHUS-Hopital Fleurimont

Abdenour Nabid
Ph: 819-820-6480
Email: crcinformation.chus@ssss.gouv.qc.ca

Saskatchewan
Regina

Allan Blair Cancer Centre at Pasqua Hospital

Tak Hing P Tai
Ph: 306-766-2213

Saskatoon

Saskatoon Cancer Centre at the University of Saskatchewan

Ali A El-Gayed
Ph: 306-655-2914

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT00936390
ClinicalTrials.gov processed this data on April 09, 2015

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.