Testosterone in Treating Postmenopausal Patients With Arthralgia Caused by Adjuvant Aromatase Inhibitor Treatment

  • Resize font
  • Print
  • Email
  • Facebook
  • Twitter
  • Google+
  • Pinterest

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIIBiomarker/Laboratory analysis, Supportive care, TreatmentActive18 and overNCI, OtherA221102
CDR0000730083, NCI-2012-00719, U10CA037447, CALGB-A221102, NCCTG-N10C7, NCT01573442

Trial Description

Summary

RATIONALE: Testosterone may help relieve moderate or severe arthralgia associated with the use of aromatase inhibitors, such as anastrozole or letrozole.

PURPOSE: This randomized phase III trial studies testosterone to see how well it works compared to placebo in treating postmenopausal patients with arthralgia caused by anastrozole or letrozole.

Further Study Information

OUTLINE:

This is a multicenter study. Patients are randomized to 1 of 2 treatment arms. Patients receive testosterone transdermally on day 1 and then at 3 months on Arm I. Patients receive placebo transdermally on day 1 and then at 3 months on Arm II. The primary objective of the study is to determine whether testosterone will reduce aromatase inhibitor (AI)-induced arthralgia and associated joint symptoms. The secondary objective of the study is to explore whether testosterone will have an acceptable safety and tolerability profile, with particular reference to androgenic adverse events including acne, hirsutism, and alopecia. After completion of study treatment, patients are followed up for 6 months.

Eligibility Criteria

DISEASE CHARACTERISTICS:

  • Women who have undergone a total mastectomy or breast-conserving surgery for primary breast cancer +/-chemotherapy and +/-radiotherapy
  • Receiving anastrozole (1 mg) or letrozole (2.5 mg) orally once a day, for ≥ 21 days prior to registration
  • Must have BOTH estrogen receptor-positive (ER+) and progesterone receptor-positive (PR+) tumors and BOTH must be ≥ 30% positive
  • ≥ 5/10 arthralgia (in hands, wrist, knees, or hips) while being treated with anastrozole or letrozole which is felt by the patient to be caused by their aromatase inhibitor, as measured by verbally addressing the following question: "Please rate your pain by picking a number, from 0 to 10 (0 being none and 10 being as bad as you can imagine) that best describes your pain from your aromatase inhibitor breast cancer medication on AVERAGE, over the past week."
  • No presence of residual or recurrent cancer (locally or metastatic)

PATIENT CHARACTERISTICS:

  • Body Mass Index (BMI) between 18 and 32 kg/m²
  • Women who are postmenopausal by surgery, radiotherapy, or presence of natural amenorrhea ≥ 12 months
  • Serum glutamic oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) ≤ 1.5 times upper limit of normal (ULN)
  • ECOG Performance Status (PS) 0, 1, or 2
  • Serum creatinine ≤1.5 times ULN
  • Hemoglobin > 11 g/dL
  • White blood cell (WBC) > 3,000/mm³
  • Platelets > 100,000/mm³
  • Ability to complete questionnaire(s) by themselves or with assistance
  • Willing to provide informed written consent
  • Willing to return to an Alliance enrolling institution for follow-up
  • Willing to provide blood samples for correlative research purposes
  • No diabetes mellitus or glucose intolerance, defined as a fasting glucose > 125 mg/dL
  • No history of coronary artery disease (angina or myocardial infarction)
  • No known hypersensitivity to any component of testosterone
  • No history of a deep venous thrombosis or a thromboembolism

PRIOR CONCURRENT THERAPY:

  • See Disease Characteristics
  • No patients on hormone-replacement therapy (HRT) ≤ 4 weeks before prior to registration
  • No prolonged systemic corticosteroid treatment, except for topical applications (e.g., for rash), inhaled sprays (e.g., for obstructive airway diseases), eye drops, or local injections (e.g., intra-articular)
  • Short duration (< 2 weeks) of systemic corticosteroids is allowed (e.g., for chronic obstructive pulmonary disease), but not within 30 days prior to registration
  • Not receiving any other investigational agent
  • No concurrent use of the aromatase inhibitor exemestane
  • No concurrent radiation therapy or chemotherapy
  • No current or planned use of cyclosporine, anticoagulants, oxyphenbutazone, insulin, oral or injectable vitamin D doses over 4,000 IU/day or tamoxifen

Trial Contact Information

Trial Lead Organizations/Sponsors

Alliance for Clinical Trials in Oncology

  • National Cancer Institute
Charles L. Loprinzi, Principal Investigator

Trial Sites

U.S.A.

California
Auburn

Auburn Radiation Oncology

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Sutter Auburn Faith Hospital

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Berkeley

Alta Bates Summit Comprehensive Cancer Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Burlingame

Peninsula Medical Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Cameron Park

Radiation Oncology Centers - Cameron Park

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Davis

Sutter Davis Hospital

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Fremont

Washington Township Hospital

Vandana B Sharma
Ph: 510-745-6433

Los Angeles

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center

Armando E Giuliano
Ph: 310-423-8965

Modesto

Memorial Medical Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Mountain View

Palo Alto Medical Foundation

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Novato

Sutter Health Western Division Cancer Research Group

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Palo Alto

Palo Alto Medical Foundation - Palo Alto

David S Leibowitz
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Roseville

Radiation Oncology Center - Roseville

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Sutter Cancer Center at Roseville Medical Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Sacramento

Sutter Cancer Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

San Francisco

California Pacific Medical Center - California Campus

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Santa Cruz

Palo Alto Medical Foundation-Santa Cruz

Glenn D Wong
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Santa Rosa

Sutter Pacific Medical Foundation

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Sunnyvale

Palo Atlo Medical Foundation-Sunnyvale

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Vacaville

Solano Radiation Oncology Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Vallejo

Sutter Solano Medical Center

Peter P. Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Colorado
Aurora

Medical Center of Aurora - South Campus

Keren Sturtz
Ph: 888-785-6789

Boulder

Boulder Community Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers-Boulder

Keren Sturtz
Ph: 888-785-6789

Colorado Springs

Penrose Cancer Center at Penrose Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers at the Pavilion

Keren Sturtz
Ph: 888-785-6789

Denver

CCOP - Colorado Cancer Research Program

Keren Sturtz
Ph: 888-785-6789

Colorado Blood Cancer Institute

Keren Sturtz
Ph: 888-785-6789

Porter Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Presbyterian - St. Luke's Medical Center

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Denver Midtown

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers-Rose

Keren Sturtz
Ph: 888-785-6789

Rose Medical Center

Keren Sturtz
Ph: 888-785-6789

St. Joseph Hospital

Keren Sturtz
Ph: 888-785-6789

Durango

Mercy Medical Center

Keren Sturtz
Ph: 888-785-6789

Englewood

Comprehensive Cancer Care and Research Institute of Colorado LLC

Keren Sturtz
Ph: 888-785-6789

Swedish Medical Center

Keren Sturtz
Ph: 888-785-6789

Golden

Mountain Blue Cancer Care Center

Keren Sturtz
Ph: 888-785-6789

Greeley

North Colorado Medical Center

Keren Sturtz
Ph: 888-785-6789

Greenwood Village

Breast Cancer Care Consultants

Keren Sturtz
Ph: 888-785-6789

Lakewood

Rocky Mountain Cancer Centers-Lakewood

Keren Sturtz
Ph: 888-785-6789

St. Anthony Central Hospital

Keren Sturtz
Ph: 888-785-6789

Littleton

Littleton Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Lone Tree

Rocky Mountain Cancer Centers - Lone Tree

Keren Sturtz
Ph: 888-785-6789

Sky Ridge Medical Center

Keren Sturtz
Ph: 888-785-6789

Longmont

Hope Cancer Care Center at Longmont United Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Longmont

Keren Sturtz
Ph: 888-785-6789

Loveland

McKee Medical Center

Keren Sturtz
Ph: 888-785-6789

Parker

Parker Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Parker

Keren Sturtz
Ph: 888-785-6789

Pueblo

Rocky Mountain Cancer Centers - Pueblo

Keren Sturtz
Ph: 888-785-6789

St. Mary - Corwin Regional Medical Center

Keren Sturtz
Ph: 888-785-6789

Wheat Ridge

Exempla Lutheran Medical Center

Keren Sturtz
Ph: 888-785-6789

Florida
Lakeland

Lakeland Regional Cancer Center at Lakeland Regional Medical Center

Madhavi L. Venigalla
Ph: 863-904-1900

Georgia
Atlanta

Northside Hospital Cancer Center

Colleen S Austin
Ph: 404-303-3355

Columbus

John B. Amos Cancer Center

Andrew W. Pippas
Ph: 706-660-6404

Idaho
Coeur D'Alene

Kootenai Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Post Falls

Kootenai Cancer Center - Post Falls

Benjamin Thomas Marchello
Ph: 800-648-6274

Sandpoint

Kootenai Cancer

Benjamin Thomas Marchello
Ph: 800-648-6274

Illinois
Harvey

Ingalls Cancer Care Center at Ingalls Memorial Hospital

Mark F. Kozloff
Ph: 708-915-4673
Email: clinicaltrials@ingalls.org

La Grange

La Grange Memorial Hospital

James E. Hannigan
Ph: 800-323-8622

Moline

Garneau, Stewart C MD (UIA Investigator)

David M Spector
Ph: 309-779-4200

Spector, David MD (UIA Investigator)

David M Spector
Ph: 309-779-4200

Trinity Cancer Center at Trinity Medical Center - 7th Street Campus

David M Spector
Ph: 309-779-4200

Indiana
Mishawaka

Memorial Regional Cancer Center Day Road

Thomas Joseph Reid
Ph: 800-284-7370

Richmond

Reid Hospital & Health Care Services

Howard M. Gross
Ph: 937-775-1350

South Bend

Memorial Hospital of South Bend

Thomas Joseph Reid
Ph: 800-284-7370

Iowa
Ames

McFarland Clinic, PC

Joseph James Merchant
Ph: 515-239-2621

William R. Bliss Cancer Center at Mary Greeley Medical Center

Joseph James Merchant
Ph: 515-239-2621

Bettendorf

Constantinou, Costas L MD (UIA Investigator)

David M Spector
Ph: 309-779-4200

Hematology Oncology Associates of the Quad Cities

Shobha R. Chitneni
Ph: 563-355-7733
Email: kedaprile@rccqc.com

Boone

McFarland Clinic PC-Boone

Joseph James Merchant
Ph: 515-239-2621

Cedar Rapids

Cedar Rapids Oncology Associates

Deborah W Wilbur
Ph: 319-363-2690

Mercy Regional Cancer Center at Mercy Medical Center

Deborah W Wilbur
Ph: 319-363-2690

Fort Dodge

Trinity Regional Medical Center

Joseph James Merchant
Ph: 515-239-2621

Jefferson

McFarland Clinic PC-Jefferson

Joseph James Merchant
Ph: 515-239-2621

Marshalltown

McFarland Clinic PC-Marshalltown

Joseph James Merchant
Ph: 515-239-2621

Kentucky
Crestview Hills

Oncology Hematology Care, Incorporated - Crestview Hills

Howard M. Gross
Ph: 937-775-1350

Edgewood

St. Elizabeth Medical Center

Joseph Michael Guenther
Ph: 859-301-5473
Email: darla.hehman@stelizabeth.com

Fort Thomas

St. Luke Hospital East

Joseph Michael Guenther
Ph: 859-301-5473
Email: darla.hehman@stelizabeth.com

Louisiana
Baton Rouge

Ochsner Health Center - Bluebonnet

John T Cole
Ph: 888-562-4763

New Orleans

New Orleans Cancer Institute at Memorial Medical Center

John T Cole
Ph: 888-562-4763

Ochsner Cancer Institute at Ochsner Clinic Foundation

John T Cole
Ph: 888-562-4763

Maryland
Rockville

Unidentified Site

Charles L. Loprinzi
Ph: 507-284-4849
Email: loprinzi@mayo.edu

Massachusetts
Danvers

NSMC Cancer Center - Peabody

Beverly Moy
Ph: 877-726-5130

Newton

Newton-Wellesley Hospital

Beverly Moy
Ph: 877-726-5130

Michigan
Escanaba

Green Bay Oncology, Limited - Escanaba

Anthony J. Jaslowski
Ph: 800-432-6049

Iron Mountain

Green Bay Oncology - Iron Mountain

Anthony J. Jaslowski
Ph: 800-432-6049

Minnesota
Bemidji

MeritCare Bemidji

Preston D. Steen
Ph: 701-234-6161

Mankato

Immanuel St. Joseph's

Mohmmad J Ranginwala
Ph: 507-385-2929

Rochester

Mayo Clinic Cancer Center

Charles L. Loprinzi
Ph: 507-538-7623

Missouri
Saint Louis

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

Rebecca L Aft
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Montana
Billings

Billings Clinic Cancer Center - 801 N 29th Street

Benjamin Thomas Marchello
Ph: 800-648-6274

CCOP - Montana Cancer Consortium

Benjamin Thomas Marchello
Ph: 800-648-6274

St. Vincent Healthcare Cancer Care Services

Benjamin Thomas Marchello
Ph: 800-648-6274

Bozeman

Bozeman Deaconess Cancer Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Butte

St. James Healthcare Cancer Care

Benjamin Thomas Marchello
Ph: 800-648-6274

Great Falls

Benefis Sletten Cancer Institute

Benjamin Thomas Marchello
Ph: 800-648-6274

Helena

St. Peter's Hospital

Benjamin Thomas Marchello
Ph: 800-648-6274

Kalispell

Kalispell Regional Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Missoula

Community Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Montana Cancer Center at St. Patrick Hospital and Health Sciences Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Nevada
Henderson

21st Century Oncology - Henderson

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Henderson

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Henderson

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada-Southeast Henderson

John Allan Ellerton
Ph: 702-384-0013

Las Vegas Cancer Center - Henderson

John Allan Ellerton
Ph: 702-384-0013

Las Vegas

21st Century Oncology - Fort Apache

John Allan Ellerton
Ph: 702-384-0013

21st Century Oncology - Vegas Sunrise

John Allan Ellerton
Ph: 702-384-0013

21st Century Oncology - Vegas Tenaya

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Fort Apache

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Shadow

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Tenaya

John Allan Ellerton
Ph: 702-384-0013

Cancer Institute of Nevada at Summerlin Hospital Medical Center

John Allan Ellerton
Ph: 702-384-0013

Cancer Therapy and Integrative Medicine

John Allan Ellerton
Ph: 702-384-0013

CCOP - Nevada Cancer Research Foundation

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Central Valley

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Northwest

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Southwest

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-San Martin

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

John Allan Ellerton
Ph: 702-384-0013

Las Vegas Cancer Center-Medical Center

John Allan Ellerton
Ph: 702-384-0013

Radiation Oncology Centers of Las Vegas - Downtown Location

John Allan Ellerton
Ph: 702-384-0013

Radiation Oncology Centers of Las Vegas - Eastern Location

John Allan Ellerton
Ph: 702-384-0013

University Medical Center of Southern Nevada

John Allan Ellerton
Ph: 702-384-0013

New Hampshire
Londonderry

Dana-Farber Cancer Institute at Londonderry

Beverly Moy
Ph: 877-726-5130

New Jersey
Englewood

Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center

Jill S Morrison
Ph: 201-894-3456

New York
Middletown

Tucker Center for Cancer Care at Orange Regional Medical Center

Jeffrey M. Stewart
Ph: 845-342-7609

North Carolina
Charlotte

Carolina Surgical Clinic of Charlotte, PA

Justin P Favaro
Ph: 704-384-5369

Oncology Specialists of Charlotte

Justin P Favaro
Ph: 704-384-5369

Presbyterian Cancer Center at Presbyterian Hospital

Justin P Favaro
Ph: 704-384-5369

Southern Oncology Specialists

Justin P Favaro
Ph: 704-384-5369

Clinton

Southeastern Medical Oncology Center-Clinton

James N. Atkins
Ph: 919-580-0000

Goldsboro

Southeastern Medical Oncology Center - Goldsboro

James N. Atkins
Ph: 919-580-0000

Wayne Memorial Hospital, Incorporated

James N. Atkins
Ph: 919-580-0000

Huntersville

Lake Norman Hematology Oncology Specialists-Huntersville

Justin P Favaro
Ph: 704-384-5369

Southern Oncology Specialists

Justin P Favaro
Ph: 704-384-5369

Jacksonville

Southeastern Medical Oncology Center-Jacksonville

James N. Atkins
Ph: 919-580-0000

Kinston

Kinston Medical Specialists

Peter R. Watson
Ph: 252-559-2200

Matthews

Matthews Hematology Oncology Associates

Justin P Favaro
Ph: 704-384-5369

Southeast Radiation Oncology Group, PA at Matthews Radiation Oncology Center

Justin P Favaro
Ph: 704-384-5369

Mooresville

Lake Norman Hematology Oncology Specialists

Justin P Favaro
Ph: 704-384-5369

Wilson

Southeastern Medical Oncology Center - Wilson

James N. Atkins
Ph: 919-580-0000

North Dakota
Fargo

Roger Maris Cancer Center at MeritCare Hospital

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Ph: 701-234-6161

Sanford Clinic North-Fargo

Preston D. Steen
Ph: 701-234-6161

Ohio
Cincinnati

Bethesda North Hospital

Ching Ho
Ph: 513-862-2230

Oncology Hematology Care Inc - Western Hills

Howard M. Gross
Ph: 937-775-1350

Oncology Hematology Care, Incorporated - Anderson

Howard M. Gross
Ph: 937-775-1350

Oncology Hematology Care, Incorporated - Blue Ash

Howard M. Gross
Ph: 937-775-1350

Oncology Hematology Care, Incorporated - Kenwood

Howard M. Gross
Ph: 937-775-1350

Oncology Hematology Care, Incorporated - Mt. Auburn/Taft Road

Howard M. Gross
Ph: 937-775-1350

University of Cincinnati

Mahmoud Charif
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Dayton

David L. Rike Cancer Center at Miami Valley Hospital

Howard M. Gross
Ph: 937-775-1350

Good Samaritan Hospital

Howard M. Gross
Ph: 937-775-1350

Samaritan North Cancer Care Center

Howard M. Gross
Ph: 937-775-1350

Fairfield

Oncology Hematology Care, Incorporated - Fairfield Healthplex

Howard M. Gross
Ph: 937-775-1350

Findlay

Blanchard Valley Regional Cancer Center

Howard M. Gross
Ph: 937-775-1350

Franklin

Atrium Medical Center

Howard M. Gross
Ph: 937-775-1350

Greenville

Wayne Hospital

Howard M. Gross
Ph: 937-775-1350

Kettering

Charles F. Kettering Memorial Hospital

Howard M. Gross
Ph: 937-775-1350

Troy

UVMC Cancer Care Center at Upper Valley Medical Center

Howard M. Gross
Ph: 937-775-1350

West Chester

University Pointe

Mahmoud Charif
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Wright-Patterson Afb

United States Air Force Medical Center - Wright-Patterson

Brandon J Cutler
Ph: 937-257-1398

Pennsylvania
Sayre

Guthrie Cancer Center at Guthrie Clinic Sayre

Cynthia A Lynch
Ph: 800-836-0388

Williamsport

Susquehanna Cancer Center at Divine Providence Hospital

Warren L Robinson
Ph: 800-598-4282

PR
San Juan

San Juan City Hospital

Luis Baez-Diaz
Ph: 787-767-3733

Tennessee
Bristol

Wellmont-Bristol Regional Medical Center

Asheesh Shipstone
Ph: 423-578-8538

Johnson City

Wellmont Medical Associates Oncology and Hematology-Johnson City

Asheesh Shipstone
Ph: 423-578-8538

Kingsport

Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center

Asheesh Shipstone
Ph: 423-578-8538

Kingsport Hematology-Oncology Associates

Asheesh Shipstone
Ph: 423-578-8538

Virginia
Fairfax

Medical Oncology and Hematology Associates of North Virginia - Fairfax

Mary J Wilkinson
Ph: 703-720-5210ext1044

Martinsville

Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County

Sreedhar Katragadda
Ph: 276-666-7827

Norton

Southwest Virginia Regional Cancer Center at Wellmonth Health

Asheesh Shipstone
Ph: 423-578-8538

Wisconsin
Burlington

Aurora Cancer Care-Burlington

Rubina Qamar
Ph: 888-709-2080

Elkhorn

Vince Lombardi Cancer Center at Aurora Lakeland Medical Center - Elkhorn

Rubina Qamar
Ph: 888-709-2080

Fond Du Lac

Aurora Health Center-Fond du Lac

Rubina Qamar
Ph: 888-709-2080

Grafton

Aurora Cancer Care-Grafton

Rubina Qamar
Ph: 888-709-2080

Green Bay

Green Bay Oncology, Limited at St. Mary's Hospital

Anthony J. Jaslowski
Ph: 800-432-6049

Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center

Anthony J. Jaslowski
Ph: 800-432-6049

St. Mary's Hospital Medical Center - Green Bay

Anthony J. Jaslowski
Ph: 800-432-6049

St. Vincent Hospital Regional Cancer Center

Anthony J. Jaslowski
Ph: 800-432-6049

Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center

Rubina Qamar
Ph: 888-709-2080

Kenosha

Oncology Alliance - Kenosha South

Rubina Qamar
Ph: 888-709-2080

La Crosse

Franciscan Skemp Healthcare - La Crosse Campus

Paula Gill
Ph: 608-392-9462

Manitowoc

Holy Family Memorial Medical Center Cancer Care Center

Anthony J. Jaslowski
Ph: 800-432-6049

Marinette

Bay Area Cancer Care Center at Bay Area Medical Center

Anthony J. Jaslowski
Ph: 800-432-6049

Vince Lombardi Cancer Clinic - Marinette

Rubina Qamar
Ph: 888-709-2080

Menomonee Falls

Aurora Advanced Healthcare Inc-Menomonee Falls

Rubina Qamar
Ph: 888-709-2080

Milwaukee

Aurora Cancer Care-Milwaukee

Rubina Qamar
Ph: 888-709-2080

Aurora Sinai Medical Center

Rubina Qamar
Ph: 888-709-2080

Oncology Alliance, SC - Milwaukee - South

Rubina Qamar
Ph: 888-709-2080

Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center

Rubina Qamar
Ph: 888-709-2080

Oconto Falls

Green Bay Oncology, Limited - Oconto Falls

Anthony J. Jaslowski
Ph: 800-432-6049

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

Rubina Qamar
Ph: 888-709-2080

Racine

Aurora Health Center - Racine

Rubina Qamar
Ph: 888-709-2080

Sheboygan

Saint Nicholas Hospital

Anthony J. Jaslowski
Ph: 800-432-6049

Vince Lombardi Cancer Clinic - Sheboygan

Rubina Qamar
Ph: 888-709-2080

Sturgeon Bay

Green Bay Oncology, Limited - Sturgeon Bay

Anthony J. Jaslowski
Ph: 800-432-6049

Summit

Aurora Medical Center

Rubina Qamar
Ph: 888-709-2080

Two Rivers

Vince Lombardi Cancer Clinic - Two Rivers

Rubina Qamar
Ph: 888-709-2080

Waukesha

Aurora Cancer Care-Waukesha

Rubina Qamar
Ph: 888-709-2080

Wauwatosa

Oncology Alliance, SC - Milwaukee - West

Rubina Qamar
Ph: 888-709-2080

West Allis

Aurora Women's Pavilion of West Allis Memorial Hospital

Rubina Qamar
Ph: 888-709-2080

Wyoming
Cheyenne

Cheyenne Regional Medical Center

Keren Sturtz
Ph: 888-785-6789

Cody

Big Horn Basin Cancer Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Billings Clinic-Cody

Benjamin Thomas Marchello
Ph: 800-648-6274

Sheridan

Welch Cancer Center at Sheridan Memorial Hospital

Benjamin Thomas Marchello
Ph: 800-648-6274

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT01573442
ClinicalTrials.gov processed this data on April 09, 2015

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.