Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

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Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IITreatmentActive18 and overNCINCI-2013-01732
ECOG-E3612, E3612, U10CA180820, U10CA021115, NCT01950390

Trial Description

Summary

This randomized phase II trial studies how well ipilimumab with or without bevacizumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery. Monoclonal antibodies, such as ipilimumab and bevacizumab, block tumor growth in different ways by targeting certain cells.

Further Study Information

PRIMARY OBJECTIVES:

I. To compare overall survival for patients receiving ipilimumab plus bevacizumab versus ipilimumab alone.

SECONDARY OBJECTIVES:

I. To evaluate the progression free survival, response rate and safety in patients receiving ipilimumab plus bevacizumab versus ipilimumab alone.

II. To evaluate the utility of immune related response criteria (irRC) in patients receiving ipilimumab plus bevacizumab versus ipilimumab alone.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM A:

INDUCTION THERAPY: Patients receive ipilimumab intravenously (IV) over 90 minutes on day 1. Treatment repeats every 21 days for 4 courses in the absence of disease progression or unacceptable toxicity.

MAINTENANCE THERAPY: Beginning course 8, patients receive ipilimumab IV over 90 minutes on day 1. Courses repeat every 12 weeks in the absence of disease progression or unacceptable toxicity.

ARM B:

INDUCTION THERAPY: Patients receive ipilimumab IV over 90 minutes and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 4 courses in the absence of disease progression or unacceptable toxicity.

MAINTENANCE THERAPY: Patients receive bevacizumab as in Induction Therapy. Beginning course 8, patients also receive ipilimumab IV over 90 minutes on day 1. Courses repeat every 12 weeks in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up for 5 years.

Eligibility Criteria

Inclusion Criteria:

  • Eastern Cooperative Oncology Group (ECOG) performance status: 0 or 1
  • Untreated or previously received one treatment for measurable unresectable stage III or stage IV melanoma (American Joint Committee on Cancer [AJCC] 2010) (regardless of v-raf murine sarcoma viral oncogene homolog B [BRAF] mutation status or human leukocyte antigen [HLA] type); this does not include any therapies given in the adjuvant setting
  • Prior treatment (chemotherapy [chemo], radiation, hormone, and immune therapies) must be completed > 4 weeks prior to randomization (> 6 weeks prior to randomization for nitrosoureas, mitomycin C, and checkpoint inhibitors)
  • Patients who received prior therapy with anthracyclines should have a baseline multigated acquisition scan (MUGA) or echocardiogram (echo) with a normal ejection fraction within 28 days prior to randomization
  • Patients must have recovered from any acute toxicity associated with prior therapy by the start of study treatment
  • Women must not be pregnant or breast-feeding; all females of childbearing potential must have a blood test or urine study within 2 weeks prior to randomization to rule out pregnancy; a female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)
  • All sites of disease must be evaluated within 4 weeks prior to randomization; patients must have measurable disease
  • White blood cell (WBC) >= 2000/uL
  • Absolute neutrophil count (ANC) >= 1000/uL
  • Platelets >= 75 x 10^3/uL
  • Hemoglobin >= 9 g/dL
  • Creatinine =< 2.0 x upper limit of normal (ULN)
  • Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x ULN for patients without liver metastases and =< 5 x ULN for patients with liver metastases
  • Serum bilirubin =< 2.0 x ULN (except patients with Gilbert's syndrome, who must have a total bilirubin less than 3.0 mg/dL)
  • Patients BRAF mutation status must be known
  • No concomitant therapy with any of the following: interleukin (IL) 2, interferon, or other non-study immunotherapy regimens; cytotoxic chemotherapy; immunosuppressive agents; other investigational therapies; or chronic use of systemic corticosteroids; must have been discontinued >= 4 weeks prior to randomization
  • No infection with human immunodeficiency virus (HIV)
  • No active infection with hepatitis B
  • No active or chronic infection with hepatitis C
  • Patients are ineligible if they have any history of central nervous system (CNS) metastases
  • Patients are ineligible if they have a history of any other malignancy from which the patient has been disease-free for less than 2 years, with the exception of adequately treated and cured basal or squamous cell skin cancer, superficial bladder cancer or carcinoma in situ of the cervix
  • Patients are ineligible if they have a history of autoimmune disease, as follows: patients with a history of inflammatory bowel disease are excluded from this study as are patients with a history of symptomatic disease (e.g., rheumatoid arthritis, systemic progressive sclerosis [scleroderma], systemic lupus erythematosus, autoimmune vasculitis [e.g., Wegener's granulomatosis]); patients with motor neuropathy considered of autoimmune origin (e.g., Guillain-Barre syndrome and myasthenia gravis) are excluded; patients with a history of autoimmune thyroiditis are eligible if their current thyroid disorder is treated and stable with replacement or other medical therapy
  • Patients are ineligible if they have an active infection
  • Patients are ineligible if they have a history of prior treatment with ipilimumab, bevacizumab, or prior tumor necrosis factor receptor superfamily, member 9 (CD137) agonist or cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) inhibitor or agonist; patients may be treatment naïve or have had one prior systemic therapy for metastatic disease as outlined in the eligibility criteria; patients may have received prior anti-programmed cell death (PD)-1 or anti-programmed cell death ligand (PD-L)1 as per current protocol eligibility, although they are not currently commercially approved in the front line setting
  • Patients are ineligible if they have a history of any underlying medical or psychiatric conditions or require any medications or treatment that in the opinion of the principal investigator may interfere with compliance, make the administration of study drug hazardous or obscure the interpretation of adverse events, such as a condition associated with frequent diarrhea
  • Patients are ineligible if they have any concurrent medical condition requiring the use of systemic steroids; (use of inhaled or topical steroids is acceptable)
  • Patients are ineligible if they have inadequately controlled hypertension (defined as systolic blood pressure > 150 and/or diastolic blood pressure > 100 mmHg on antihypertensive medications)
  • Patients are excluded if they have any prior history of hypertensive crisis or hypertensive encephalopathy
  • Patients are excluded if they have New York Heart Association (NYHA) grade II or greater congestive heart failure
  • Patients are excluded if they have a history of myocardial infarction or unstable angina within 6 months prior to randomization
  • Patients are excluded if they have a history of stroke or transient ischemic attack within 6 months prior to randomization
  • Patients are excluded if they have known significant vascular disease (e.g., aortic aneurysm, aortic dissection)
  • Patients are excluded if they have symptomatic peripheral vascular disease
  • Patients are excluded if they have evidence of bleeding diathesis or coagulopathy
  • Patients are excluded if they have had a surgical procedure or a significant traumatic injury within 28 days prior to randomization
  • Patients are excluded if they have had a biopsy or other minor surgical procedure, excluding placement of a vascular access device, within 7 days prior to randomization
  • Patients are excluded if they have history of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within 6 months prior to randomization
  • Patients are excluded if they have a non-healing wound or ulcer
  • Patients are excluded if they have proteinuria at screening as demonstrated by either:
  • Urine dipstick for proteinuria >= 2+ (patients discovered to have >= 2+ proteinuria on dipstick urinalysis at baseline should undergo a 24 hour urine collection and must demonstrate =< 1 g of protein in 24 hours to be eligible) OR
  • Urine protein: creatinine (UPC) ratio >= 1.0 at screening; for UPC ratio > 1, a 24 hour urine protein should be obtained and the level should be < 1000mg; NOTE: urine protein should be screened by urine analysis for UPC ratio; a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 g
  • Patients must not have known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
  • Patients are excluded if they have a history of hemoptysis (bright red blood of 1/2 teaspoon or more per episode) within 3 months prior to randomization
  • Patients are excluded if they have current, ongoing treatment with full-dose warfarin or its equivalent (i.e., unfractionated and/or low molecular weight heparin); subjects should have not taken full-dose warfarin or equivalent for at least 2 weeks prior to randomization
  • Patients are excluded if they have current or recent (within 10 days of enrollment) use of aspirin (> 325 mg/day) or chronic use of other non-steroidal anti-inflammatory drugs (NSAID)
  • Patients are excluded if they use medications that inhibit platelet function (e.g., dipyridamole, epoprostenol, eptifibatide, clopidogrel, cilostazol, abciximab, ticlopidine, and ibuprofen and related compounds) unless subject has been off treatment for at least 2 weeks prior to randomization
  • Patients are excluded if they have known involvement of melanoma within the gastrointestinal tract
  • Patients are excluded for any non-oncology vaccine therapy used for prevention of infectious diseases (for up to 1 month before or after any dose of ipilimumab)
  • Women of childbearing potential and sexually active males must agree to practice abstinence or use an accepted and effective method of contraception

Trial Contact Information

Trial Lead Organizations/Sponsors

National Cancer Institute

    Frank Hodi, Principal Investigator

    Trial Sites

    U.S.A.

    Alabama
    Birmingham

    UAB Comprehensive Cancer Center

    Robert M Conry
    Ph: 888-823-5923
    Email: ctsucontact@westat.com

    Mobile

    University of South Alabama Mitchell Cancer Institute

    Thomas W Butler
    Ph: 251-445-9870
    Email: pfrancisco@usouthal.edu

    Connecticut
    Hartford

    Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Norwich

    Eastern Connecticut Hematology and Oncology Associates

    Dennis E. Slater
    Ph: 860-886-8362

    Stamford

    Carl and Dorothy Bennett Cancer Center at Stamford Hospital

    Salvatore A. Del Prete
    Ph: 203-323-8944

    Delaware
    Lewes

    Tunnell Cancer Center at Beebe Medical Center

    Gregory A. Masters
    Ph: 302-733-6227

    Newark

    Christiana Gynecologic Oncology, LLC

    Gregory A. Masters
    Ph: 302-733-6227

    Delaware Clinical and Laboratory Physicians

    Gregory A. Masters
    Ph: 302-733-6227

    Helen F. Graham Cancer Center at Christiana Hospital

    Gregory A. Masters
    Ph: 302-733-6227

    Gregory A. Masters
    Ph: 302-733-6227

    Medical Oncology Hematology Consultants, PA at Helen F. Graham Cancer Center

    Gregory A. Masters
    Ph: 302-733-6227

    Regional Hematology/Oncology, PA - Newark

    Gregory A. Masters
    Ph: 302-733-6227

    Rehoboth Beach

    Beebe Health Campus

    Gregory A. Masters
    Ph: 302-733-6227

    Seaford

    Nanticoke Memorial Hospital

    Gregory A. Masters
    Ph: 302-733-6227

    Wilmington

    Christiana Care Health System-Wilmington Hospital

    Gregory A. Masters
    Ph: 302-733-6227

    Florida
    Lakeland

    Lakeland Regional Cancer Center at Lakeland Regional Medical Center

    Madhavi L. Venigalla
    Ph: 863-904-1900

    Miami Beach

    CCOP - Mount Sinai Medical Center

    Jose Lutzky
    Ph: 305-674-2625
    Email: info@msccop.com

    Georgia
    Atlanta

    Winship Cancer Institute of Emory University

    David H. Lawson
    Ph: 404-778-1868

    Savannah

    Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler

    Howard A. Zaren
    Ph: 800-622-6877

    Hawaii
    Aiea

    Kapiolani Medical Center at Pali Momi

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Ewa Beach

    Leeward Radiation Oncology

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Honolulu

    Cancer Research Center of Hawaii

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Hawaii Medical Center - East

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Kapiolani Medical Center for Women and Children

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Kuakini Medical Center

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    OnCare Hawaii, Incorporated - Kuakini

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    OnCare Hawaii, Incorporated - Lusitana

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Queen's Cancer Institute at Queen's Medical Center

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Straub Clinic and Hospital, Incorporated

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Lihue

    Kauai Medical Clinic

    Jeffrey L. Berenberg
    Ph: 808-586-2979

    Idaho
    Boise

    Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Coeur D'Alene

    Kootenai Medical Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Post Falls

    Kootenai Cancer Center - Post Falls

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Sandpoint

    Kootenai Cancer

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Illinois
    Aurora

    Rush-Copley Cancer Care Center

    Wenqing Zhang
    Ph: 800-446-5532

    Bloomington

    Illinois CancerCare - Bloomington

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    St. Joseph Medical Center

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Canton

    Illinois CancerCare - Canton

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Carbondale

    Memorial Hospital of Carbondale

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Carthage

    Illinois CancerCare - Carthage

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Centralia

    Centralia Oncology Clinic

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Chicago

    Robert H. Lurie Comprehensive Cancer Center at Northwestern University

    Timothy M. Kuzel
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Saint Joseph Hospital

    Ira Oliff
    Ph: 773-665-3109

    Danville

    Carle on Vermilion

    Wenqing Zhang
    Ph: 800-446-5532

    Decatur

    Cancer Care Center of Decatur

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Decatur Memorial Hospital Cancer Care Institute

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Effingham

    Carle Physician Group-Effingham

    Wenqing Zhang
    Ph: 800-446-5532

    Crossroads Cancer Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Eureka

    Illinois CancerCare - Eureka

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Galesburg

    Galesburg Clinic, PC

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Medical and Surgical Specialists, LLC

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Highland Park

    Hematology Oncology Associates of Illinois-Highland Park

    Timothy M. Kuzel
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Hinsdale

    Hinsdale Hematology Oncology Associates

    Elyse Cheryl Schneiderman
    Ph: 630-654-1790
    Email: info@hhoaltd.com

    Joliet

    Joliet Oncology-Hematology Associates, Limited - West

    Kulumani M Sivarajan
    Ph: 815-730-3098
    Email: maureenc@jolietoncology.com

    Kankakee

    Provena St. Mary's Regional Cancer Center - Kankakee

    Timothy M. Kuzel
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Kewanee

    Illinois CancerCare - Kewanee Clinic

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Libertyville

    North Shore Oncology and Hematology Associates, Limited - Libertyville

    Timothy M. Kuzel
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Macomb

    Illinois CancerCare - Macomb

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Mattoon

    Carle Physician Group-Mattoon/Charleston

    Wenqing Zhang
    Ph: 800-446-5532

    Moline

    Garneau, Stewart C MD (UIA Investigator)

    David M Spector
    Ph: 309-779-4200

    Spector, David MD (UIA Investigator)

    David M Spector
    Ph: 309-779-4200

    Trinity Cancer Center at Trinity Medical Center - 7th Street Campus

    David M Spector
    Ph: 309-779-4200

    Mount Vernon

    Good Samaritan Regional Health Center

    Jay W Carlson
    Ph: 800-821-7532

    Niles

    Cancer Care and Hematology Specialists of Chicagoland - Niles

    Timothy M. Kuzel
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Ottawa

    Illinois CancerCare - Ottawa

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Pekin

    Cancer Treatment Center at Pekin Hospital

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Illinois CancerCare - Pekin

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Peoria

    Illinois CancerCare - Peoria

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Methodist Medical Center of Illinois

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    OSF St. Francis Medical Center

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Peru

    Illinois CancerCare - Princeton

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Princeton

    Illinois CancerCare - Princeton

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Rockford

    Advanced Care and Treatment Medical Group, PC

    Harvey Eric Einhorn
    Ph: 779-696-9400
    Email: cancercare@swedishamerican.org

    Skokie

    Hematology Oncology Associates - Skokie

    Timothy M. Kuzel
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Springfield

    Regional Cancer Center at Memorial Medical Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Urbana

    Carle Cancer Center at Carle Foundation Hospital

    Wenqing Zhang
    Ph: 800-446-5532

    Wenqing Zhang
    Ph: 800-446-5532

    Yorkville

    Rush-Copley Healthcare Center

    Wenqing Zhang
    Ph: 800-446-5532

    Indiana
    Michigan City

    Saint Anthony Memorial Health Centers

    Wenqing Zhang
    Ph: 800-446-5532

    Woodland Cancer Care Center

    Wenqing Zhang
    Ph: 800-446-5532

    Richmond

    Reid Hospital & Health Care Services

    Howard M. Gross
    Ph: 937-775-1350

    Iowa
    Ames

    McFarland Clinic, PC

    Joseph James Merchant
    Ph: 515-239-2621

    William R. Bliss Cancer Center at Mary Greeley Medical Center

    Joseph James Merchant
    Ph: 515-239-2621

    Bettendorf

    Constantinou, Costas L MD (UIA Investigator)

    David M Spector
    Ph: 309-779-4200

    Boone

    McFarland Clinic PC-Boone

    Joseph James Merchant
    Ph: 515-239-2621

    Des Moines

    John Stoddard Cancer Center at Iowa Lutheran Hospital

    Robert J Behrens
    Ph: 515-282-2921

    John Stoddard Cancer Center at Iowa Methodist Medical Center

    Robert J Behrens
    Ph: 515-282-2921

    Medical Oncology and Hematology Associates at John Stoddard Cancer Center

    Robert J Behrens
    Ph: 515-282-2921

    Fairfield

    JCHC McCreery Cancer Center

    Robert J Behrens
    Ph: 515-282-2921

    Fort Dodge

    Trinity Regional Medical Center

    Joseph James Merchant
    Ph: 515-239-2621

    Jefferson

    McFarland Clinic PC-Jefferson

    Joseph James Merchant
    Ph: 515-239-2621

    Marshalltown

    McFarland Clinic PC-Marshalltown

    Joseph James Merchant
    Ph: 515-239-2621

    Mason City

    Mercy Cancer Center at Mercy Medical Center - North Iowa

    Arvind Y Vemula
    Ph: 800-433-3883

    Ottumwa

    South Iowa Radiation Oncology Center at Ottumwa Regional Health Center

    Robert J Behrens
    Ph: 515-282-2921

    Sioux City

    Siouxland Hematology-Oncology Associates, LLP

    Donald Bruce Wender
    Ph: 712-252-0088

    West Des Moines

    Methodist West Hospital

    Robert J Behrens
    Ph: 515-282-2921

    Kansas
    Chanute

    Cancer Center of Kansas, PA - Chanute

    Shaker R. Dakhil
    Ph: 316-262-4467

    Dodge City

    Cancer Center of Kansas, PA - Dodge City

    Shaker R. Dakhil
    Ph: 316-262-4467

    El Dorado

    Cancer Center of Kansas, PA - El Dorado

    Shaker R. Dakhil
    Ph: 316-262-4467

    Fort Scott

    Cancer Center of Kansas - Fort Scott

    Shaker R. Dakhil
    Ph: 316-262-4467

    Independence

    Cancer Center of Kansas-Independence

    Shaker R. Dakhil
    Ph: 316-262-4467

    Kingman

    Cancer Center of Kansas, PA - Kingman

    Shaker R. Dakhil
    Ph: 316-262-4467

    Lawrence

    Lawrence Memorial Hospital

    Shaker R. Dakhil
    Ph: 316-262-4467

    Liberal

    Cancer Center of Kansas, PA - Liberal

    Shaker R. Dakhil
    Ph: 316-262-4467

    Newton

    Cancer Center of Kansas, PA - Newton

    Shaker R. Dakhil
    Ph: 316-262-4467

    Parsons

    Cancer Center of Kansas, PA - Parsons

    Shaker R. Dakhil
    Ph: 316-262-4467

    Pratt

    Cancer Center of Kansas, PA - Pratt

    Shaker R. Dakhil
    Ph: 316-262-4467

    Salina

    Cancer Center of Kansas, PA - Salina

    Shaker R. Dakhil
    Ph: 316-262-4467

    Wellington

    Cancer Center of Kansas, PA - Wellington

    Shaker R. Dakhil
    Ph: 316-262-4467

    Wichita

    Associates in Women's Health, PA - North Hillside

    Shaker R. Dakhil
    Ph: 316-262-4467

    Cancer Center of Kansas, PA - Medical Arts Tower

    Shaker R. Dakhil
    Ph: 316-262-4467

    Cancer Center of Kansas, PA - Wichita

    Shaker R. Dakhil
    Ph: 316-262-4467

    Via Christi Cancer Center at Via Christi Regional Medical Center

    Shaker R. Dakhil
    Ph: 316-262-4467

    Winfield

    Cancer Center of Kansas, PA - Winfield

    Shaker R. Dakhil
    Ph: 316-262-4467

    Kentucky
    Crestview Hills

    Oncology Hematology Care, Incorporated - Crestview Hills

    Howard M. Gross
    Ph: 937-775-1350

    Maine
    Augusta

    Harold Alfond Center for Cancer Care

    Thomas Henry Openshaw
    Ph: 207-973-4274

    Bangor

    CancerCare of Maine at Eastern Maine Medical Center

    Thomas Henry Openshaw
    Ph: 207-973-4274

    Brewer

    Lafayette Family Cancer Center-EMMC

    Thomas Henry Openshaw
    Ph: 207-973-4274

    Rockport

    Penobscot Bay Medical Center Cancer Care Center

    Thomas Henry Openshaw
    Ph: 207-973-4274

    Massachusetts
    Boston

    Beth Israel Deaconess Medical Center

    F. Stephen Hodi
    Ph: 866-790-4500

    Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute

    F. Stephen Hodi
    Ph: 866-790-4500

    Massachusetts General Hospital

    F. Stephen Hodi
    Ph: 866-790-4500

    Springfield

    Baystate Medical Center

    John McCann
    Ph: 413-794-3565
    Email: tamara.wrenn@baystatehealth.org

    Michigan
    Adrian

    Hickman Cancer Center at Bixby Medical Center

    Rex B Mowat
    Ph: 800-444-3561

    Ann Arbor

    Saint Joseph Mercy Cancer Center

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Dearborn

    Oakwood Cancer Center at Oakwood Hospital and Medical Center

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Detroit

    Van Elslander Cancer Center at St. John Hospital and Medical Center

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Wayne State University

    Amy Weise
    Ph: 313-576-9363

    Flint

    Genesys Hurley Cancer Institute

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Hurley Medical Center

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Jackson

    Gayle M. Jacob Cancer Center at Allegiance Health

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Kalamazoo

    Borgess Medical Center

    Sunil Nagpal
    Ph: 269-373-7458

    Bronson Methodist Hospital

    Sunil Nagpal
    Ph: 269-373-7458

    West Michigan Cancer Center

    Sunil Nagpal
    Ph: 269-373-7458

    Lansing

    Sparrow Regional Cancer Center

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Livonia

    St. Mary Mercy Hospital

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Monroe

    Community Cancer Center of Monroe

    Rex B Mowat
    Ph: 800-444-3561

    Pontiac

    St. Joseph Mercy Oakland

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Port Huron

    Mercy Regional Cancer Center at Mercy Hospital

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Saginaw

    Seton Cancer Institute at Saint Mary's - Saginaw

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Warren

    St. John Macomb Hospital

    Tareq Al Baghdadi
    Ph: 734-712-4673

    Minnesota
    Bemidji

    MeritCare Bemidji

    Preston D. Steen
    Ph: 701-234-6161

    Saint Cloud

    CentraCare Clinic - Women and Children

    Donald J Jurgens
    Ph: 877-229-4907
    Email: coborncancercenter@centracare.com

    Coborn Cancer Center

    Donald J Jurgens
    Ph: 877-229-4907
    Email: coborncancercenter@centracare.com

    Missouri
    Bonne Terre

    Parkland Health Center-Bonne Terre

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Cape Girardeau

    Saint Francis Medical Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Southeast Cancer Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Jefferson City

    Goldschmidt Cancer Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Joplin

    St. John's Regional Medical Center

    Jay W Carlson
    Ph: 800-821-7532

    Rolla

    Mercy Clinic Cancer and Hematology - Rolla

    Jay W Carlson
    Ph: 800-821-7532

    Saint Louis

    David C. Pratt Cancer Center at St. John's Mercy

    Jay W Carlson
    Ph: 800-821-7532

    Mercy Clinic St. Louis Cancer and Breast Institute

    Jay W Carlson
    Ph: 800-821-7532

    Missouri Baptist Cancer Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Springfield

    Hulston Cancer Center at Cox Medical Center South

    Jay W Carlson
    Ph: 800-821-7532

    St. John's Regional Health Center

    Jay W Carlson
    Ph: 800-821-7532

    Sullivan

    Missouri Baptist Sullivan Hospital

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Sunset Hills

    Missouri Baptist Outpatient Center-Sunset Hills

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Montana
    Billings

    Billings Clinic Cancer Center - 801 N 29th Street

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    CCOP - Montana Cancer Consortium

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    St. Vincent Healthcare Cancer Care Services

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Bozeman

    Bozeman Deaconess Cancer Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Butte

    St. James Healthcare Cancer Care

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Great Falls

    Benefis Sletten Cancer Institute

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Helena

    St. Peter's Hospital

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Kalispell

    Kalispell Regional Medical Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Missoula

    Community Medical Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Montana Cancer Center at St. Patrick Hospital and Health Sciences Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Nebraska
    Lincoln

    Cancer Resource Center - Lincoln

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Nebraska Hematology and Oncology

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Southeast Nebraska Hematology Oncology Consultants at Southeast Nebraska Cancer Center

    Gamini S. Soori
    Ph: 402-991-8070
    Email: mwilwerding@mvcc.cc

    Norfolk

    Carson Cancer Center at Faith Regional Hospital

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    North Platte

    Callahan Cancer Center at Great Plains Regional Medical Center

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Omaha

    CCOP - Missouri Valley Cancer Consortium

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Oncology Hematology West PC

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Oncology Hematology West, PC - Omaha Bergan

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Scottsbluff

    Cancer Treatment Center at Regional West Medical Center

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Nevada
    Henderson

    21st Century Oncology - Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer and Blood Specialists-Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada - Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada-Southeast Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Las Vegas Cancer Center - Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Las Vegas

    21st Century Oncology - Fort Apache

    John Allan Ellerton
    Ph: 702-384-0013

    21st Century Oncology - Vegas Sunrise

    John Allan Ellerton
    Ph: 702-384-0013

    21st Century Oncology - Vegas Tenaya

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer and Blood Specialists-Fort Apache

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer and Blood Specialists-Shadow

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer and Blood Specialists-Tenaya

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer Institute of Nevada at Summerlin Hospital Medical Center

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer Therapy and Integrative Medicine

    John Allan Ellerton
    Ph: 702-384-0013

    CCOP - Nevada Cancer Research Foundation

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada - Central Valley

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada - Northwest

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada - Southwest

    John Allan Ellerton
    Ph: 702-384-0013

    HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

    John Allan Ellerton
    Ph: 702-384-0013

    HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

    John Allan Ellerton
    Ph: 702-384-0013

    HealthCare Partners Medical Group Oncology/Hematology-San Martin

    John Allan Ellerton
    Ph: 702-384-0013

    HealthCare Partners Medical Group Oncology/Hematology-Tenaya

    John Allan Ellerton
    Ph: 702-384-0013

    Las Vegas Cancer Center-Medical Center

    John Allan Ellerton
    Ph: 702-384-0013

    Radiation Oncology Centers of Las Vegas - Downtown Location

    John Allan Ellerton
    Ph: 702-384-0013

    Radiation Oncology Centers of Las Vegas - Eastern Location

    John Allan Ellerton
    Ph: 702-384-0013

    University Medical Center of Southern Nevada

    John Allan Ellerton
    Ph: 702-384-0013

    New Hampshire
    Lebanon

    Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center

    Bradley A Arrick
    Ph: 800-639-6918
    Email: cancer.research.nurse@dartmouth.edu

    Manchester

    Norris Cotton Cancer Center at Catholic Medical Center

    Bradley A Arrick
    Ph: 800-639-6918
    Email: cancer.research.nurse@dartmouth.edu

    Nashua

    Norris Cotton Cancer Center Nashua

    Bradley A Arrick
    Ph: 800-639-6918
    Email: cancer.research.nurse@dartmouth.edu

    New Jersey
    Hackensack

    CCOP - Northern New Jersey

    Donna T McNamara
    Ph: 201-996-2879

    Hackensack University Medical Center Cancer Center

    Donna T McNamara
    Ph: 201-996-2879

    Vineland

    Frank and Edith Scarpa Regional Cancer Pavillion at South Jersey Healthcare

    Benjamin P Negin
    Ph: 856-641-7933

    Woodbury

    Underwood Memorial Hospital

    Carl J. Minniti
    Ph: 856-641-7933

    New York
    Auburn

    Hematology Oncology Associates of Central New York-Auburn

    Jeffrey J. Kirshner
    Ph: 315-472-7504

    Bronx

    Albert Einstein Cancer Center at Albert Einstein College of Medicine

    Stuart H Packer
    Ph: 718-904-2730
    Email: aecc@aecom.yu.edu

    Jack D. Weiler Hospital at Montefiore Medical Center - East Campus

    Stuart H Packer
    Ph: 718-904-2730
    Email: aecc@aecom.yu.edu

    Montefiore Medical Center

    Stuart H Packer
    Ph: 718-904-2730
    Email: aecc@aecom.yu.edu

    Cooperstown

    Bassett Healthcare Regional Cancer Program at Mary Imogene Bassett Hospital

    Eric Bravin
    Ph: 607-547-3073
    Email: diana.crean@bassett.org

    East Syracuse

    CCOP - Hematology-Oncology Associates of Central New York

    Jeffrey J. Kirshner
    Ph: 315-472-7504

    Syracuse

    Hematology Oncology Associates of Central New York-Onondaga Hill

    Jeffrey J. Kirshner
    Ph: 315-472-7504

    White Plains

    Dickstein Cancer Treatment Center at White Plains Hospital Center

    Dan Costin
    Ph: 914-681-2290

    North Carolina
    Clinton

    Southeastern Medical Oncology Center-Clinton

    James N. Atkins
    Ph: 919-580-0000

    Goldsboro

    Southeastern Medical Oncology Center - Goldsboro

    James N. Atkins
    Ph: 919-580-0000

    Wayne Memorial Hospital, Incorporated

    James N. Atkins
    Ph: 919-580-0000

    Hendersonville

    Comprehensive Cancer Center at Pardee Hospital

    James E. Radford
    Ph: 828-696-4716

    Hendersonville Hematology and Oncology

    James E. Radford
    Ph: 828-696-4716

    Jacksonville

    Southeastern Medical Oncology Center-Jacksonville

    James N. Atkins
    Ph: 919-580-0000

    Kinston

    Kinston Medical Specialists

    Peter R. Watson
    Ph: 252-559-2200

    Statesville

    Iredell Memorial Hospital

    Ruby A. Grimm
    Ph: 704-873-5661

    Wilson

    Southeastern Medical Oncology Center - Wilson

    James N. Atkins
    Ph: 919-580-0000

    North Dakota
    Bismarck

    Medcenter One Hospital Cancer Care Center

    Preston D. Steen
    Ph: 701-234-6161

    Fargo

    Roger Maris Cancer Center at MeritCare Hospital

    Preston D. Steen
    Ph: 701-234-6161

    Preston D. Steen
    Ph: 701-234-6161

    Sanford Clinic North-Fargo

    Preston D. Steen
    Ph: 701-234-6161

    Ohio
    Akron

    Summa Center for Cancer Care at Akron City Hospital

    Jennifer E Payne
    Ph: 330-375-6101

    Belpre

    Strecker Cancer Center-Belpre

    J. Philip Kuebler
    Ph: 614-566-3275

    Canton

    Aultman Cancer Center at Aultman Hospital

    James A. Schmotzer
    Ph: 330-363-6891

    Chillicothe

    Adena Regional Medical Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Cincinnati

    Christ Hospital Cancer Center

    Philip D. Leming
    Ph: 513-585-2859

    Oncology Hematology Care Inc - Western Hills

    Howard M. Gross
    Ph: 937-775-1350

    Oncology Hematology Care, Incorporated - Anderson

    Howard M. Gross
    Ph: 937-775-1350

    Oncology Hematology Care, Incorporated - Blue Ash

    Howard M. Gross
    Ph: 937-775-1350

    Oncology Hematology Care, Incorporated - Kenwood

    Howard M. Gross
    Ph: 937-775-1350

    Oncology Hematology Care, Incorporated - Mt. Auburn/Taft Road

    Howard M. Gross
    Ph: 937-775-1350

    Columbus

    Columbus Oncology Associates, Incorporated

    J. Philip Kuebler
    Ph: 614-566-3275

    Doctors Hospital at Ohio Health

    J. Philip Kuebler
    Ph: 614-566-3275

    Grant Medical Center Cancer Care

    J. Philip Kuebler
    Ph: 614-566-3275

    Mount Carmel Health - West Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Riverside Methodist Hospital Cancer Care

    J. Philip Kuebler
    Ph: 614-566-3275

    Zangmeister Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Dayton

    David L. Rike Cancer Center at Miami Valley Hospital

    Howard M. Gross
    Ph: 937-775-1350

    Good Samaritan Hospital

    Howard M. Gross
    Ph: 937-775-1350

    Samaritan North Cancer Care Center

    Howard M. Gross
    Ph: 937-775-1350

    Delaware

    Delaware Health Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Delaware Radiation Oncology

    J. Philip Kuebler
    Ph: 614-566-3275

    Grady Memorial Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Fairfield

    Oncology Hematology Care, Incorporated - Fairfield Healthplex

    Howard M. Gross
    Ph: 937-775-1350

    Findlay

    Blanchard Valley Regional Cancer Center

    Howard M. Gross
    Ph: 937-775-1350

    Franklin

    Atrium Medical Center

    Howard M. Gross
    Ph: 937-775-1350

    Greenville

    Wayne Hospital

    Howard M. Gross
    Ph: 937-775-1350

    Kettering

    Charles F. Kettering Memorial Hospital

    Howard M. Gross
    Ph: 937-775-1350

    Lancaster

    Fairfield Medical Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Marietta

    Strecker Cancer Center at Marietta Memorial Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Maumee

    Northwest Ohio Oncology Center

    Rex B Mowat
    Ph: 800-444-3561

    Rex B Mowat
    Ph: 800-444-3561

    Mount Vernon

    Knox Community Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Newark

    Licking Memorial Cancer Care Program at Licking Memorial Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Newark Radiation Oncology

    J. Philip Kuebler
    Ph: 614-566-3275

    Oregon

    St. Charles Mercy Hospital

    Rex B Mowat
    Ph: 800-444-3561

    Portsmouth

    Southern Ohio Medical Center Cancer Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Springfield

    Community Hospital of Springfield and Clark County

    J. Philip Kuebler
    Ph: 614-566-3275

    Sylvania

    Flower Hospital Cancer Center

    Rex B Mowat
    Ph: 800-444-3561

    Toledo

    CCOP - Toledo Community Hospital

    Rex B Mowat
    Ph: 800-444-3561

    St. Anne Mercy Hospital

    Rex B Mowat
    Ph: 800-444-3561

    Toledo Clinic, Incorporated - Main Clinic

    Rex B Mowat
    Ph: 800-444-3561

    University of Toledo Medical Center

    Rex B Mowat
    Ph: 800-444-3561

    Troy

    UVMC Cancer Care Center at Upper Valley Medical Center

    Howard M. Gross
    Ph: 937-775-1350

    Westerville

    Mount Carmel St. Ann's Cancer Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Zanesville

    Genesis - Good Samaritan Hospital

    J. Philip Kuebler
    Ph: 614-488-2745
    Email: sheree@columbusccop.org

    Oklahoma
    Oklahoma City

    Mercy Health Center

    Vikki Ann Canfield
    Ph: 405-751-4343

    Stephenson Cancer Center at the University of Oklahoma

    Alexandra P Ikeguchi
    Ph: 405-271-4272
    Email: julie-traylor@ouhsc.edu

    Tulsa

    Cancer Care Associates-Yale

    Alexandra P Ikeguchi
    Ph: 405-271-4272
    Email: julie-traylor@ouhsc.edu

    Oregon
    Salem

    Salem Hospital Regional Cancer Care Services

    John Strother
    Ph: 503-561-2618

    Pennsylvania
    Abington

    Rosenfeld Cancer Center at Abington Memorial Hospital

    Willard G. Andrews
    Ph: 215-481-2402

    Bryn Mawr

    Bryn Mawr Hospital

    Albert S DeNittis
    Ph: 866-225-5654

    Danville

    Geisinger Cancer Institute at Geisinger Health

    Christian Adonizio
    Ph: 570-271-5251

    Doylestown

    Doylestown Hospital Cancer Center

    Mitchell Alden
    Ph: 215-345-2378
    Email: lheacock@dh.org

    Hazleton

    Geisinger Hazleton Cancer Center

    Christian Adonizio
    Ph: 570-271-5251

    Hershey

    Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center

    Joseph Drabick
    Ph: 717-531-3779
    Email: CTO@hmc.psu.edu

    Lancaster

    Lancaster General Hospital

    Shanthi Sivendran
    Ph: 717-544-5511

    Lewisburg

    Geisinger Medical Oncology at Evangelical Community Hospital

    Christian Adonizio
    Ph: 570-271-5251

    Lewistown

    Lewistown Hospital

    Christian Adonizio
    Ph: 570-271-5251

    Media

    Riddle Memorial Hospital Cancer Center

    Albert S DeNittis
    Ph: 866-225-5654

    Paoli

    Cancer Center of Paoli Memorial Hospital

    Albert S DeNittis
    Ph: 866-225-5654

    Philadelphia

    Fox Chase Cancer Center - Philadelphia

    Sujana Movva
    Ph: 215-728-4790

    Pittsburgh

    UPMC Cancer Centers

    Ahmad A. Tarhini
    Ph: 412-647-8073

    Pottsville

    Geisinger Medical Oncology-Pottsville

    Christian Adonizio
    Ph: 570-271-5251

    Scranton

    Scranton Hematology Oncology

    Martin B. Hyzinski
    Ph: 570-558-3020

    State College

    Geisinger Medical Group - Scenery Park

    Christian Adonizio
    Ph: 570-271-5251

    West Chester

    Cancer Center of Chester County

    William E. Luginbuhl
    Ph: 610-431-5297

    West Reading

    McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

    Terrence P. Cescon
    Ph: 610-988-9323

    Wilkes-Barre

    Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center

    Christian Adonizio
    Ph: 570-271-5251

    Wynnewood

    Lankenau Cancer Center at Lankenau Hospital

    Albert S DeNittis
    Ph: 866-225-5654

    South Carolina
    Anderson

    AnMed Cancer Center

    John E Doster
    Ph: 864-512-1000

    Easley

    Cancer Centers of the Carolinas - Easley

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Greenville

    Cancer Centers of the Carolinas - Andrews

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Cancer Centers of the Carolinas - Faris Road

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Cancer Centers of the Carolinas - Grove Commons

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    CCOP - Greenville

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Greenville Memorial Hospital

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Greer

    Cancer Centers of the Carolinas - Greer Radiation Oncology

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Seneca

    Cancer Centers of the Carolinas - Seneca

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Spartanburg

    Cancer Centers of the Carolinas - Spartanburg

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    South Dakota
    Rapid City

    Rapid City Regional Hospital

    Mark T Schroeder
    Ph: 605-716-3982
    Email: research@rcrh.org

    Sioux Falls

    Sanford Cancer Center at Sanford USD Medical Center

    Preston D. Steen
    Ph: 701-234-6161

    Preston D. Steen
    Ph: 701-234-6161

    West Virginia
    Morgantown

    Mary Babb Randolph Cancer Center at West Virginia University Hospitals

    Manish Monga
    Ph: 304-293-2745
    Email: sfilburn@hsc.wvu.edu

    Wisconsin
    Antigo

    Langlade Memorial Hospital

    Hamied R. Rezazadeh
    Ph: 877-405-6866

    Eau Claire

    Center for Cancer Treatment & Prevention at Sacred Heart Hospital

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Marshfield Clinic Cancer Care at Regional Cancer Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Green Bay

    Bellin Memorial Hospital

    Patrick J Mansky
    Ph: 240-566-3584
    Email: clinicaltrials@fmh.org

    Johnson Creek

    UW Cancer Center Johnson Creek

    Mark R. Albertini
    Ph: 877-405-6866

    La Crosse

    Gundersen Lutheran Center for Cancer and Blood

    Kurt Oettel
    Ph: 608-775-2385
    Email: cancerctr@gundluth.org

    Madison

    University of Wisconsin Paul P. Carbone Comprehensive Cancer Center

    Mark R. Albertini
    Ph: 877-405-6866

    Marshfield

    Marshfield Clinic - Marshfield Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Saint Joseph's Hospital

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Milwaukee

    Froedtert Hospital and Medical College of Wisconsin

    Stuart J. Wong
    Ph: 414-805-4380

    Minocqua

    Marshfield Clinic - Lakeland Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Mukwonago

    D.N. Greenwald Center

    Timothy R Wassenaar
    Ph: 262-928-7878

    Oconomowoc

    Regional Cancer Center at Oconomowoc Memorial Hospital

    Timothy R Wassenaar
    Ph: 262-928-7878

    Rhinelander

    Ministry Medical Group at Saint Mary's Hospital

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Rice Lake

    Marshfield Clinic - Indianhead Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Stevens Point

    Marshfield Clinic at Saint Michael's Hospital

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Saint Michael's Hospital Cancer Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Waukesha

    Waukesha Memorial Hospital Regional Cancer Center

    Timothy R Wassenaar
    Ph: 262-928-7878

    Wausau

    Marshfield Clinic - Wausau Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    University of Wisconcin Cancer Center at Aspirus Wausau Hospital

    Hamied R. Rezazadeh
    Ph: 877-405-6866

    Weston

    Diagnostic and Treatment Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Marshfield Clinic - Weston Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Ministry Saint Clare's Hospital

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Wisconsin Rapids

    Marshfield Clinic - Wisconsin Rapids Center

    Seth Olusegun Fagbemi
    Ph: 715-389-4457

    Riverview UW Cancer Center at Riverview Hospital

    Ron James Kirschling
    Ph: 877-405-6866

    Wyoming
    Cody

    Big Horn Basin Cancer Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Billings Clinic-Cody

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Sheridan

    Welch Cancer Center at Sheridan Memorial Hospital

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Link to the current ClinicalTrials.gov record.
    NLM Identifier NCT01950390
    ClinicalTrials.gov processed this data on May 26, 2015

    Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.