Crizotinib

  (krih-ZOH-tih-nib)

This page contains brief information about crizotinib and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s):		Xalkori
FDA Approved:		Yes

FDA Approval for Crizotinib

Crizotinib is approved to treat:

• Non-small cell lung cancer that is locally advanced or has metastasized (spread to other parts of the body). It is used in patients who have a certain type of chromosome change that affects the anaplastic lymphoma kinase (ALK) gene.

Crizotinib is also being studied in the treatment of other types of cancer.

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Crizotinib - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Clinical Trial Results: Crizotinib Improves Progression-Free Survival in Some Patients With Advanced Lung Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Crizotinib Continues to Show Promise for Some Lung Tumors, Faces Challenge of Drug Resistance - Important clinical trial results for this drug, background information, and how the trial was done.

FDA Approves New Drugs to Treat Skin, Blood, and Lung Cancers - Information about the use of this drug to treat cancer.

For Lung Cancer, a New Drug and a Way Forward - Information about the use of this drug to treat cancer.

Find Clinical Trials for Crizotinib - Check for trials from NCI's list of cancer clinical trials now accepting patients.

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