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This page contains brief information about dacarbazine and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s):		DTIC-Dome
FDA Approved:		Yes

Dacarbazine is approved by the Food and Drug Administration (FDA) to be used by itself to treat melanoma that has metastasized (spread to other parts of the body).

Dacarbazine is also approved to be used with other drugs to treat Hodgkin lymphoma in patients whose disease has not gotten better with other chemotherapy.

In addition to the uses that have been approved by the FDA, dacarbazine is sometimes used to treat other types of cancer. It is also being studied in the treatment of some types of cancer.

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

Clinical Trial Results: PET Can Strongly Predict Likelihood of Early Relapse in Hodgkin Lymphoma - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Lower-Toxicity Treatment Effective in Some Cases of Early-Stage Hodgkin Lymphoma - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemoimmunotherapy No Better Than Combination Chemotherapy Alone for Metastatic Melanoma - Important clinical trial results for this drug, background information, and how the trial was done.

MedlinePlus Information on Dacarbazine - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This NLM patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Clinical Trials for Dacarbazine - Check for trials from NCI's PDQ Cancer Clinical Trials Registry now accepting patients.

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