Basic Trial Information
Trial Description
     Summary
     Further Trial Information
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

Trial Description

Summary

RATIONALE: Drugs used in chemotherapy, such as carboplatin, paclitaxel, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. Giving chemotherapy and radiation therapy after surgery may kill any tumor cells that remain after surgery. It is not yet known whether carboplatin and paclitaxel are more effective with or without cisplatin and radiation therapy in treating patients with endometrial cancer.

PURPOSE: This randomized phase III trial is studying carboplatin and paclitaxel to see how well they work when given with or without cisplatin and radiation therapy in treating patients with stage I, stage II, stage III, or stage IVA endometrial cancer.

Further Study Information

OBJECTIVES:

Primary

• Compare the recurrence-free survival of patients with stage I-IVA endometrial carcinoma treated with adjuvant chemoradiotherapy comprising cisplatin and tumor volume-directed radiotherapy followed by carboplatin and paclitaxel vs carboplatin and paclitaxel alone.

Secondary

• Compare the overall survival of patients treated with these regimens.

• Compare the acute and late adverse effects of these regimens in these patients.

• Determine the impact of these regimens on patient-reported quality of life during and for up to 1 year after completion of study treatment.

OUTLINE: This is a multicenter study. Patients are randomized to 1 of 2 treatment arms.

• Arm I: Patients receive cisplatin IV on days 1 and 29. Patients also undergo external-beam radiotherapy once daily, 5 days a week, for 5-6 weeks. Some patients may then undergo brachytherapy over 2-3 weeks. Beginning within 8 weeks after completion of chemoradiotherapy, patients receive paclitaxel IV over 3 hours and carboplatin IV on day 1. Treatment repeats every 21 days for 4 courses in the absence of disease progression or unacceptable toxicity.

• Arm II: Patients receive paclitaxel IV over 3 hours and carboplatin IV on day 1. Treatment repeats every 21 days for 6 courses in the absence of disease progression or unacceptable toxicity.

Patients complete quality-of-life questionnaires at baseline and periodically during study using the FACT-G Physical and Functional Well-Being, FACT-Endometrial, FACT/GOG Neuropathy, and FACT-C (items C3 and C5).

After completion of study therapy, patients are followed up every 3 months for 2 years, every 6 months for 3 years, and then annually thereafter.

Eligibility Criteria

DISEASE CHARACTERISTICS:

• Histologically confirmed endometrial carcinoma, including the following cell types:

• Clear cell carcinoma

• Serous papillary carcinoma

• Undifferentiated carcinoma

• Surgical stage III or IVA disease per FIGO 2009 staging criteria

• Surgical stage III disease includes positive adnexa, tumor invading the serosa, positive pelvic and/or para-aortic nodes, or vaginal involvement

• Surgical stage IVA disease includes bladder or bowel mucosal involvement, but no spread outside the pelvis

• Surgical stage I or II endometrial clear cell or serous papillary carcinoma with positive peritoneal cytology per FIGO 2009 staging criteria

• Has undergone optimal surgical debulking that included a hysterectomy and bilateral salpingo-oophorectomy within the past 8 weeks

• Residual tumor after surgery (any single site) ≤ 2 cm in maximum dimension

• No carcinosarcoma

• No parenchymal liver metastases

• No recurrent endometrial cancer or endometrioid stage I or II with positive peritoneal cytology

PATIENT CHARACTERISTICS:

• GOG performance status 0-2

• Life expectancy ≥ 3 months

• WBC ≥ 3,000/mm^3

• ANC ≥ 1,500/mm^3

• Platelet count ≥ 100,000/mm^3

• SGOT and SGPT ≤ 2.5 times upper limit of normal (ULN)

• Alkaline phosphatase ≤ 2.5 times ULN

• Bilirubin ≤ 1.5 times ULN

• Creatinine ≤ ULN

• No myocardial infarction, unstable angina, or uncontrolled arrhythmia within the past 3 months

• No other active invasive malignancy within the past 5 years except for non-melanoma skin cancer

• No history of serious co-morbid or uncontrolled illness that would preclude study therapy

PRIOR CONCURRENT THERAPY:

• See Disease Characteristics

• No prior pelvic or abdominal radiotherapy

• No prior chemotherapy for endometrial cancer

• No prior cancer treatment that would preclude study therapy

Trial Contact Information

Trial Lead Organizations/Sponsors

Gynecologic Oncology Group

Daniela E. Matei

Study Chair

U.S.A.
Alabama
	Birmingham
	UAB Comprehensive Cancer Center
		Warner Huh	Ph: 205-934-0309
	Mobile
	University of South Alabama Mitchell Cancer Institute
		Rodney P Rocconi	Ph: 251-445-9870
			Email: pfrancisco@usouthal.edu
Alaska
	Anchorage
	Providence Cancer Center
		Jeanne E. Anderson	Ph: 907-261-3109
Arizona
	Phoenix
	St. Joseph's Hospital and Medical Center
		Ivor Benjamin	Ph: 623-773-2873
	Scottsdale
	Mayo Clinic Scottsdale
		Harry J. Long	Ph: 507-538-7623
California
	Antioch
	Kaiser Permanente - Deer Valley
		Louis Fehrenbacher	Ph: 626-564-3455
	Auburn
	Auburn Radiation Oncology
		Christopher Jones	Ph: 916-646-8300
	Burbank
	Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center
		Richard Friedman	Ph: 818-847-3220
	Cameron Park
	Radiation Oncology Centers - Cameron Park
		Christopher Jones	Ph: 916-646-8300
	Carmichael
	Mercy Cancer Center at Mercy San Juan Medical Center
		Christopher Jones	Ph: 916-646-8300
	Concord
	Cancer Care Center at John Muir Health - Concord Campus
		Babak Edraki	Ph: 925-674-2580
	Fremont
	Kaiser Permanente - Fremont
		Louis Fehrenbacher	Ph: 626-564-3455
	Hayward
	Kaiser Permanente Medical Center - Hayward
		Louis Fehrenbacher	Ph: 626-564-3455
	Long Beach
	Todd Cancer Institute at Long Beach Memorial Medical Center
		Robert E Bristow	Ph: 877-827-8839
			Email: ucstudy@uci.edu
	Los Angeles
	Kaiser Permanente Medical Center - Los Angeles
		Scott E. Lentz	Ph: 626-564-3455
		Scott E. Lentz	Ph: 626-564-3455
	Modesto
	Kaiser Permanente-Modesto
		Samantha A Seaward	Ph: 626-564-3455
	Mountain View
	Palo Alto Medical Foundation
		Albert L Pisani	Ph: 650-934-7000
	Newport Beach
	Gynecologic Oncology Associates
		Lisa N Abaid	Ph: 949-642-5165
	Oakland
	Kaiser Permanente-Oakland
		Louis Fehrenbacher	Ph: 626-564-3455
	Orange
	Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center
		Krishnansu S Tewari	Ph: 714-456-6191
			Email: awallick@uci.edu
	St. Joseph Hospital Regional Cancer Center - Orange
		Michael L Berman	Ph: 877-827-8839
			Email: ucstudy@uci.edu
	Redwood City
	Kaiser Permanente Medical Center - Redwood City
		Louis Fehrenbacher	Ph: 626-564-3455
	Richmond
	Kaiser Permanente Medical Center - Richmond
		Louis Fehrenbacher	Ph: 626-564-3455
	Roseville
	Kaiser Permanente Medical Center - Roseville
		Louis Fehrenbacher	Ph: 626-564-3455
	Radiation Oncology Center - Roseville
		Christopher Jones	Ph: 916-646-8300
	Sutter Cancer Center at Roseville Medical Center
		Stacy D D'Andre	Ph: 916-454-6500
			Email: cancerinfo@sutterhealth.org
	Sacramento
	Kaiser Permanente Medical Center - Sacramento
		Louis Fehrenbacher	Ph: 626-564-3455
	Mercy General Hospital
		Christopher Jones	Ph: 916-646-8300
	Radiological Associates of Sacramento Medical Group, Incorporated
		Christopher Jones	Ph: 916-646-8300
	South Sacramento Kaiser-Permanente Medical Center
		Louis Fehrenbacher	Ph: 626-564-3455
	Sutter Cancer Center
		Stacy D D'Andre	Ph: 916-454-6500
			Email: cancerinfo@sutterhealth.org
	University of California Davis Cancer Center
		Jyoti S Mayadev	Ph: 916-734-3089
	San Diego
	Rebecca and John Moores UCSD Cancer Center
		Michael T. McHale	Ph: 858-822-5354
			Email: cancercto@ucsd.edu
	San Francisco
	Kaiser Permanente Medical Center - San Francisco Geary Campus
		Louis Fehrenbacher	Ph: 626-564-3455
	UCSF Helen Diller Family Comprehensive Cancer Center
		Lee-may Chen	Ph: 877-827-3222
	San Jose
	Kaiser Permanente Medical Center - Santa Teresa
		Louis Fehrenbacher	Ph: 626-564-3455
	San Rafael
	Kaiser Foundation Hospital - San Rafael
		Louis Fehrenbacher	Ph: 626-564-3455
	Santa Clara
	Kaiser Permanente Medical Center - Santa Clara Homestead Campus
		Louis Fehrenbacher	Ph: 626-564-3455
		Louis Fehrenbacher	Ph: 626-564-3455
	Santa Rosa
	Kaiser Permanente Medical Center - Santa Rosa
		Louis Fehrenbacher	Ph: 626-564-3455
	South San Francisco
	Kaiser Permanente Medical Center - South San Francisco
		Louis Fehrenbacher	Ph: 626-564-3455
	Stanford
	Stanford Cancer Center
		Jonathan S. Berek	Ph: 650-498-7061
			Email: clinicaltrials@med.stanford.edu
	Stockton
	Kaiser Permanente Medical Facility - Stockton
		Louis Fehrenbacher	Ph: 626-564-3455
	Sylmar
	Olive View - UCLA Medical Center Foundation
		Christine Holschneider	Ph: 888-798-0719
	Vacaville
	Kaiser Permanente Medical Center - Vacaville
		Louis Fehrenbacher	Ph: 626-564-3455
	Solano Radiation Oncology Center
		Christopher Jones	Ph: 916-646-8300
	Vallejo
	Kaiser Permanente Medical Center - Vallejo
		Louis Fehrenbacher	Ph: 626-564-3455
	Walnut Creek
	John Muir/Mt. Diablo Comprehensive Cancer Center
		Babak Edraki	Ph: 925-674-2580
	Kaiser Permanente Medical Center - Walnut Creek
		Louis Fehrenbacher	Ph: 626-564-3455
Colorado
	Aurora
	University of Colorado Cancer Center at UC Health Sciences Center
		Susan Davidson	Ph: 720-848-0650
	Fort Collins
	Front Range Cancer Specialists
		Diana C. Medgyesy	Ph: 970-212-7600
	Poudre Valley Hospital
		Paolo Romero	Ph: 970-495-8226
Connecticut
	Bridgeport
	Bridgeport Hospital
		Sheida Mani	Ph: 203-785-5702
	St. Vincent's Medical Center
		Stuart G Marcus	Ph: 203-576-6329
			Email: twhite@stvincents.org
	Hartford
	Helen and Harry Gray Cancer Center at Hartford Hospital
		James S. Hoffman	Ph: 860-224-5660
	New Britain
	George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus
		James S. Hoffman	Ph: 860-224-5660
	New Haven
	Yale Cancer Center
		Masoud Azodi	Ph: 203-785-5702
	Norwich
	Eastern Connecticut Hematology and Oncology Associates
		Dennis E. Slater	Ph: 860-886-8362
	William W. Backus Hospital
		Dennis E. Slater	Ph: 860-886-8362
Delaware
	Lewes
	Tunnell Cancer Center at Beebe Medical Center
		Mark E Borowsky	Ph: 302-733-6227
	Newark
	Helen F. Graham Cancer Center at Christiana Hospital
		Mark E Borowsky	Ph: 302-733-6227
District of Columbia
	Washington
	Sibley Memorial Hospital
		Mildred Rodriguez Chernofsky	Ph: 202-243-2373
Florida
	Jacksonville
	Mayo Clinic - Jacksonville
		Harry J. Long	Ph: 507-538-7623
	Lakeland
	Lakeland Regional Cancer Center at Lakeland Regional Medical Center
		Richard A. Boothby	Ph: 863-904-1900
	Miami
	Miami Cancer Center at Mercy Hospital
		Luis E Mendez	Ph: 305-285-2792
	University of Miami Sylvester Comprehensive Cancer Center - Miami
		Anthony Lucci	Ph: 866-574-5124
			Email: Sylvester@emergingmed.com
	Orlando
	Florida Hospital Cancer Institute at Florida Hospital Orlando
		James E Kendrick	Ph: 407-303-5623
	M.D. Anderson Cancer Center at Orlando
		Veronica L Schimp	Ph: 321-841-7246
	Sarasota
	Sarasota Memorial Hospital
		James V. Fiorica	Ph: 941-917-2225
Georgia
	Atlanta
	Northside Hospital Cancer Center
		Guilherme C. Cantuaria	Ph: 404-303-3355
			Email: clinicaltrials@northside.com
	Piedmont Hospital
		Adam W Nowlan	Ph: 404-425-7943
			Email: phri@piedmont.org
	Columbus
	John B. Amos Cancer Center
		John L Currie	Ph: 860-545-5363
	Macon
	Central Georgia Gynecologic Oncology
		Alan N Gordon	Ph: 478-633-6090
	Savannah
	Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
		James J Burke	Ph: 912-350-8568
	Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
		William Edward Richards	Ph: 800-622-6877
			Email: uchealthnews@uc.edu
Hawaii
	Aiea
	Kapiolani Medical Center at Pali Momi
		Michael E. Carney	Ph: 808-983-6090
	Honolulu
	Cancer Research Center of Hawaii
		Michael E. Carney	Ph: 808-983-6090
	Hawaii Medical Center - East
		Michael E. Carney	Ph: 808-983-6090
	Kaiser Permanente - Moanalua Medical Center and Clinic
		Louis Fehrenbacher	Ph: 626-564-3455
	Kapiolani Medical Center for Women and Children
		Michael E. Carney	Ph: 808-983-6090
	MBCCOP - Hawaii
		Michael E. Carney	Ph: 808-983-6090
	OnCare Hawaii, Incorporated - Kuakini
		Michael E. Carney	Ph: 808-983-6090
	OnCare Hawaii, Incorporated - Lusitana
		Michael E. Carney	Ph: 808-983-6090
	Queen's Cancer Institute at Queen's Medical Center
		Michael E. Carney	Ph: 808-983-6090
	Straub Clinic and Hospital, Incorporated
		Michael E. Carney	Ph: 808-983-6090
	Tripler Army Medical Center
		Bradford Paul Whitcomb	Ph: 808-433-6336
	Lihue
	Kauai Medical Clinic
		Michael E. Carney	Ph: 808-983-6090
	Wailuku
	Maui Memorial Medical Center
		Michael E. Carney	Ph: 808-983-6090
Illinois
	Bloomington
	St. Joseph Medical Center
		John W. Kugler	Ph: 800-793-2262
	Chicago
	John H. Stroger, Jr. Hospital of Cook County
		Thomas E. Lad	Ph: 312-864-6000
	Robert H. Lurie Comprehensive Cancer Center at Northwestern University
		Julian C. Schink	Ph: 312-695-1301
			Email: cancer@northwestern.edu
	Rush Cancer Institute at Rush University Medical Center
		Jacob Rotmensch	Ph: 312-942-5498
			Email: clinical_trials@rush.edu
	University of Chicago Cancer Research Center
		Seiko Diane Yamada	Ph: 773-834-7424
	Evanston
	CCOP - Evanston
		Jean A. Hurteau	Ph: 847-570-1381
	Hinsdale
	Gynecologic Oncology
		Sudarshan K. Sharma	Ph: 630-856-6757
	Normal
	BroMenn Regional Medical Center
		John W. Kugler	Ph: 800-793-2262
	Community Cancer Center
		John W. Kugler	Ph: 800-793-2262
	Oak Lawn
	Advocate Christ Medical Center
		Yvonne Cathleen Collins	Ph: 800-323-8622
	Ottawa
	Community Hospital of Ottawa
		John W. Kugler	Ph: 800-793-2262
	Illinois CancerCare - Ottawa
		John W. Kugler	Ph: 800-793-2262
	Park Ridge
	Advocate Lutheran General Cancer Care Center
		Timothy M. Lestingi	Ph: 847-384-3621
	Peoria
	CCOP - Illinois Oncology Research Association
		Nguyet A Le-Lindqwister	Ph: 800-793-2262
	Illinois CancerCare - Peoria
		John W. Kugler	Ph: 800-793-2262
	OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC
		John W. Kugler	Ph: 800-793-2262
	OSF St. Francis Medical Center
		John W. Kugler	Ph: 800-793-2262
	Rockford
	Swedish-American Regional Cancer Center
		Harvey Eric Einhorn	Ph: 815-489-4413
	Spring Valley
	Valley Cancer Center
		John W. Kugler	Ph: 800-793-2262
	Springfield
	Regional Cancer Center at Memorial Medical Center
		James L. Wade	Ph: 217-876-4740
			Email: kcheek@dmhhs.org
	Warrenville
	Central Dupage Cancer Center
		Barbara M Buttin	Ph: 630-352-5300
			Email: cancer@northwestern.edu
Indiana
	Beech Grove
	St. Francis Hospital and Health Centers - Beech Grove Campus
		David H Moore	Ph: 317-851-2555
	Dyer
	Franciscan Saint Margaret Health - Dyer Campus
		Robert D Prock	Ph: 708-891-9305
	Elkhart
	Elkhart Clinic, LLC
		Michael Rodriguez	Ph: 574-237-1328
	Elkhart General Hospital
		Michael Rodriguez	Ph: 574-237-1328
	Michiana Hematology-Oncology, PC - Elkhart
		Michael Rodriguez	Ph: 574-237-1328
	Fort Wayne
	Parkview Regional Cancer Center at Parkview Health
		Brian K Chang	Ph: 260-373-8888
			Email: parkviewresearch@parkview.com
	Radiation Oncology Associates Southwest
		Brian K Chang	Ph: 260-373-8888
			Email: parkviewresearch@parkview.com
	Hammond
	Oncology Center at Saint Margaret Mercy Healthcare Center
		Robert D Prock	Ph: 708-891-9305
	Indianapolis
	Gynecologic Oncology of Indiana
		David H Moore	Ph: 317-851-2555
	Indiana University Melvin and Bren Simon Cancer Center
		Jeanne M Schilder	Ph: 317-274-2552
	St. Vincent Oncology Center
		Gregory P. Sutton	Ph: 317-338-2194
	Kokomo
	Community Cancer Care at Howard Regional Health System
		Michael Rodriguez	Ph: 574-237-1328
	La Porte
	Center for Cancer Therapy at LaPorte Hospital and Health Services
		Michael Rodriguez	Ph: 574-237-1328
	Mishawaka
	Michiana Hematology-Oncology, PC - Mishawaka
		Michael Rodriguez	Ph: 574-237-1328
	Saint Joseph's Medical Center
		Michael Rodriguez	Ph: 574-237-1328
	Munster
	Community Hospital
		Mohamad Kassar	Ph: 219-836-3349
	Plymouth
	Michiana Hematology Oncology PC - Plymouth
		Michael Rodriguez	Ph: 574-237-1328
	South Bend
	CCOP - Northern Indiana CR Consortium
		Michael Rodriguez	Ph: 574-237-1328
	Memorial Hospital of South Bend
		Michael Rodriguez	Ph: 574-237-1328
	Michiana Hematology-Oncology, PC - South Bend
		Michael Rodriguez	Ph: 574-237-1328
	Westville
	Michiana Hematology Oncology-PC Westville
		Michael Rodriguez	Ph: 574-237-1328
Iowa
	Ames
	McFarland Clinic, PC
		Joseph James Merchant	Ph: 515-239-2621
	Clive
	Medical Oncology and Hematology Associates-West Des Moines
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Des Moines
	CCOP - Iowa Oncology Research Association
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	John Stoddard Cancer Center at Iowa Lutheran Hospital
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	John Stoddard Cancer Center at Iowa Methodist Medical Center
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Medical Oncology and Hematology Associates at John Stoddard Cancer Center
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Medical Oncology and Hematology Associates at Mercy Cancer Center
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Mercy Cancer Center at Mercy Medical Center - Des Moines
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Iowa City
	Holden Comprehensive Cancer Center at University of Iowa
		Koen De Geest	Ph: 800-237-1225
	Sioux City
	Mercy Medical Center - Sioux City
		Donald Bruce Wender	Ph: 712-252-0088
	Siouxland Hematology-Oncology Associates, LLP
		Donald Bruce Wender	Ph: 712-252-0088
	St. Luke's Regional Medical Center
		Donald Bruce Wender	Ph: 712-252-0088
Kansas
	Chanute
	Cancer Center of Kansas, PA - Chanute
		Shaker R. Dakhil	Ph: 316-262-4467
	Dodge City
	Cancer Center of Kansas, PA - Dodge City
		Shaker R. Dakhil	Ph: 316-262-4467
	El Dorado
	Cancer Center of Kansas, PA - El Dorado
		Shaker R. Dakhil	Ph: 316-262-4467
	Fort Scott
	Cancer Center of Kansas - Fort Scott
		Shaker R. Dakhil	Ph: 316-262-4467
	Independence
	Cancer Center of Kansas-Independence
		Shaker R. Dakhil	Ph: 316-262-4467
	Kansas City
	Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
		Julia A. Chapman	Ph: 913-588-4709
	Providence Medical Center
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Kingman
	Cancer Center of Kansas, PA - Kingman
		Shaker R. Dakhil	Ph: 316-262-4467
	Lawrence
	Lawrence Memorial Hospital
		Shaker R. Dakhil	Ph: 316-262-4467
	Liberal
	Cancer Center of Kansas, PA - Liberal
		Shaker R. Dakhil	Ph: 316-262-4467
	Newton
	Cancer Center of Kansas, PA - Newton
		Shaker R. Dakhil	Ph: 316-262-4467
	Overland Park
	Saint Luke's Hospital - South
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Parsons
	Cancer Center of Kansas, PA - Parsons
		Shaker R. Dakhil	Ph: 316-262-4467
	Prairie Village
	CCOP - Kansas City
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Pratt
	Cancer Center of Kansas, PA - Pratt
		Shaker R. Dakhil	Ph: 316-262-4467
	Salina
	Cancer Center of Kansas, PA - Salina
		Shaker R. Dakhil	Ph: 316-262-4467
	Wellington
	Cancer Center of Kansas, PA - Wellington
		Shaker R. Dakhil	Ph: 316-262-4467
	Wichita
	Associates in Women's Health, PA - North Hillside
		Shaker R. Dakhil	Ph: 316-262-4467
	Cancer Center of Kansas, PA - Medical Arts Tower
		Shaker R. Dakhil	Ph: 316-262-4467
	Cancer Center of Kansas, PA - Wichita
		Shaker R. Dakhil	Ph: 316-262-4467
	CCOP - Wichita
		Shaker R. Dakhil	Ph: 316-262-4467
	Via Christi Cancer Center at Via Christi Regional Medical Center
		Shaker R. Dakhil	Ph: 316-262-4467
	Wesley Medical Center
		Shaker R. Dakhil	Ph: 316-262-4467
	Winfield
	Cancer Center of Kansas, PA - Winfield
		Shaker R. Dakhil	Ph: 316-262-4467
Kentucky
	Edgewood
	St. Elizabeth Medical Center
		Jack Basil	Ph: 859-301-5473
			Email: darla.hehman@stelizabeth.com
	Lexington
	University of Kentucky Chandler Medical Center
		Frederick Ueland	Ph: 859-257-3379
	Louisville
	Louisville Oncology at Norton Cancer Institute - Louisville
		Mary E Gordinier	Ph: 502-629-2500
	Norton Suburban Hospital
		Mary E Gordinier	Ph: 502-629-2500
	University of Louisville School of Medicine
		Lynn P Parker	Ph: 866-530-5516
Louisiana
	Baton Rouge
	Woman's Hospital
		Giles Fort	Ph: 225-215-1353
			Email: clinicalreserach@marybird.com
	New Orleans
	Ochsner Cancer Institute at Ochsner Clinic Foundation
		Richard C. Kline	Ph: 888-562-4763
	Tulane Cancer Center at Tulane University Hospital and Clinic
		William R. Robinson	Ph: 504-988-6121
	Shreveport
	Feist-Weiller Cancer Center at Louisiana State University Health Sciences
		Robin A Lacour	Ph: 318-813-1412
Maine
	Bangor
	CancerCare of Maine at Eastern Maine Medical Center
		Thomas Henry Openshaw	Ph: 207-973-4274
	Portland
	Maine Medical Center - Bramhall Campus
		Laurie A. Small	Ph: 207-885-7565
Maryland
	Baltimore
	Alvin and Lois Lapidus Cancer Institute at Sinai Hospital
		Fouad M Abbas	Ph: 410-601-6120
			Email: pridgely@lifebridgehealth.org
	Greater Baltimore Medical Center Cancer Center
		Paul Celano	Ph: 443-849-3706
	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
		Deborah K. Armstrong	Ph: 410-955-8804
			Email: jhcccro@jhmi.edu
	St. Agnes Hospital Cancer Center
		Carole Miller	Ph: 410-368-2910
	Elkton MD
	Union Hospital of Cecil County
		Mark E Borowsky	Ph: 302-733-6227
Massachusetts
	Attleboro
	Sturdy Memorial Hospital
		Jonathan B Croopnick	Ph: 508-236-7059
			Email: research.department@mwmc.com
	Boston
	Tufts Medical Center Cancer Center
		Michael G Kelly	Ph: 336-713-6771
			Email: ContactUsCancerCenter@TuftsMedicalCenter.org
	Springfield
	Baystate Medical Center
		Tashanna K Myers	Ph: 413-794-3565
			Email: tamara.wrenn@baystatehealth.org
	Worcester
	Levine Cancer Center at UMass Medical Center - Memorial Campus
		Susan L. Zweizig	Ph: 508-856-2464
			Email: laura.lefko@umassmed.edu
Michigan
	Battle Creek
	Battle Creek Health System Cancer Care Center
		Gilbert D Padula	Ph: 616-685-5225
	Big Rapids
	Mecosta County Medical Center
		Gilbert D Padula	Ph: 616-685-5225
	Detroit
	Josephine Ford Cancer Center at Henry Ford Hospital
		Thomas E Buekers	Ph: 313-916-1784
	Wayne State University
		Robert T. Morris	Ph: 313-576-9363
	Escanaba
	Green Bay Oncology, Limited - Escanaba
		Jonathan E Tammela	Ph: 920-433-8889
	Grand Rapids
	Butterworth Hospital at Spectrum Health
		Gilbert D Padula	Ph: 616-685-5225
	CCOP - Grand Rapids
		Gilbert D Padula	Ph: 616-685-5225
	Gynecologic Oncology of West Michigan
		Gordon O. Downey	Ph: 616-957-3398
	Lacks Cancer Center at Saint Mary's Health Care
		Gilbert D Padula	Ph: 616-685-5225
	Iron Mountain
	Green Bay Oncology - Iron Mountain
		Jonathan E Tammela	Ph: 920-433-8889
	Kalamazoo
	Borgess Medical Center
		Raymond Sterling Lord	Ph: 269-373-7458
	Bronson Methodist Hospital
		Raymond Sterling Lord	Ph: 269-373-7458
	West Michigan Cancer Center
		Raymond Sterling Lord	Ph: 269-373-7458
	Muskegon
	Mercy General Health Partners
		Gilbert D Padula	Ph: 616-685-5225
	Reed City
	Spectrum Health Reed City Hospital
		Gilbert D Padula	Ph: 616-685-5225
	Royal Oak
	William Beaumont Hospital - Royal Oak Campus
		Donald S. Brabbins	Ph: 248-551-7695
	Saint Joseph
	Lakeside Cancer Specialists, PLLC
		Michael Rodriguez	Ph: 574-237-1328
	St. Joseph
	Lakeland Regional Cancer Care Center - St. Joseph
		Michael Rodriguez	Ph: 574-237-1328
	Traverse City
	Munson Medical Center
		Gilbert D Padula	Ph: 616-685-5225
Minnesota
	Burnsville
	Fairview Ridges Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Coon Rapids
	Mercy and Unity Cancer Center at Mercy Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Edina
	Fairview Southdale Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Fridley
	Mercy and Unity Cancer Center at Unity Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Hutchinson
	Hutchinson Area Health Care
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Maplewood
	HealthEast Cancer Care at St. John's Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Minnesota Oncology - Maplewood
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Minneapolis
	Hennepin County Medical Center - Minneapolis
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	New Ulm
	New Ulm Medical Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Robbinsdale
	Humphrey Cancer Center at North Memorial Outpatient Center
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Rochester
	Mayo Clinic Cancer Center
		Harry J. Long	Ph: 507-538-7623
	Saint Louis Park
	CCOP - Metro-Minnesota
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Park Nicollet Cancer Center
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Saint Paul
	Regions Hospital Cancer Care Center
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	United Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Shakopee
	St. Francis Cancer Center at St. Francis Medical Center
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Stillwater
	Lakeview Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Waconia
	Ridgeview Medical Center
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Willmar
	Willmar Cancer Center at Rice Memorial Hospital
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Woodbury
	Minnesota Oncology - Woodbury
		Daniel M Anderson	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
Mississippi
	Jackson
	University of Mississippi Cancer Clinic
		James Tate Thigpen	Ph: 601-815-6700
Missouri
	Columbia
	Ellis Fischel Cancer Center at University of Missouri - Columbia
		Mark I Hunter	Ph: 573-882-7440
	Kansas City
	Research Medical Center
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Saint Luke's Hospital
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Lee's Summit
	Saint Luke's East - Lee's Summit
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Rolla
	Mercy Clinic Cancer and Hematology - Rolla
		Robert L Carolla	Ph: 417-269-4520
	Saint Joseph
	Heartland Regional Medical Center
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Saint Joseph Oncology, Incorporated
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Saint Louis
	Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
		David Gardner Mutch	Ph: 800-600-3606
			Email: info@ccadmin.wustl.edu
	Springfield
	Cancer Research for the Ozarks
		Robert L Carolla	Ph: 417-269-4520
	Hulston Cancer Center at Cox Medical Center South
		Robert L Carolla	Ph: 417-269-4520
	St. John's Regional Health Center
		Robert L Carolla	Ph: 417-269-4520
Montana
	Billings
	Billings Clinic Cancer Center - 801 N 29th Street
		Benjamin Thomas Marchello	Ph: 800-648-6274
	CCOP - Montana Cancer Consortium
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Great Falls
	Benefis Sletten Cancer Institute
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Great Falls Clinic - Main Facility
		Benjamin Thomas Marchello	Ph: 800-648-6274
Nebraska
	Omaha
	Methodist Estabrook Cancer Center
		Peter C. Morris	Ph: 402-354-7939
			Email: kathryn.bartz@nmhs.org
	UNMC Eppley Cancer Center at the University of Nebraska Medical Center
		Kerry Rodabaugh	Ph: 800-999-5465
Nevada
	Las Vegas
	CCOP - Nevada Cancer Research Foundation
		John Allan Ellerton	Ph: 702-731-8274
	Women's Cancer Center - La Canada
		Nick M. Spirtos	Ph: 702-851-4672
	Reno
	Renown Institute for Cancer at Renown Regional Medical Center
		Peter C Lim	Ph: 866-513-8227
		Peter C Lim	Ph: 866-513-8227
New Hampshire
	Lebanon
	Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
		Leslie R. DeMars	Ph: 800-639-6918
			Email: cancer.research.nurse@dartmouth.edu
New Jersey
	Camden
	Cancer Institute of New Jersey at Cooper University Hospital - Camden
		David P. Warshal	Ph: 856-325-6757
	Morristown
	Carol G. Simon Cancer Center at Morristown Memorial Hospital
		Brian M Slomovitz	Ph: 973-971-5900
	Mount Holly
	Virtua Fox Chase Health Cancer Program at Virtua Memorial Hospital Burlington County
		Randolph B Deger	Ph: 888-847-8823
	Neptune
	Jersey Shore Cancer Center at Jersey Shore University Medical Center
		Michael R Manuel	Ph: 732-776-4240
			Email: clinicaltrials@med.stanford.edu
	Phillipsburg
	Women’s Institute for Gynecologic Cancer and Special Pelvic Surgery
		David Foster Silver	Ph: 718-765-2500
	Ridgewood
	Valley Hospital - Ridgewood
		William M. Burke	Ph: 201-634-5792
	Summit
	Overlook Hospital
		Brian M Slomovitz	Ph: 973-971-5900
	Voorhees
	Fox Chase Virtua Health Cancer Program at Virtua West Jersey
		Randolph B Deger	Ph: 888-847-8823
New Mexico
	Albuquerque
	Southwest Gynecologic Oncology Associates, Incorporated
		Carolyn Y. Muller	Ph: 505-272-6972
	University of New Mexico Cancer Center
		Carolyn Y. Muller	Ph: 505-272-6972
	Las Cruces
	Memorial Medical Center
		Carolyn Y. Muller	Ph: 505-272-6972
New York
	Albany
	Women's Cancer Care Associates
		Thomas P Morrissey	Ph: 518-458-1390
	Brightwaters
	Schwartz Oncology
		Benjamin M Schwartz	Ph: 631-376-0055ext107
	Brooklyn
	SUNY Downstate Medical Center
		Ovadia Abulafia	Ph: 718-270-8216
			Email: sima.terebelo@downstate.edu
	Lake Success
	Monter Cancer Center of the North Shore-LIJ Health System
		Veena S John	Ph: 516-562-3467
	Manhasset
	Don Monti Comprehensive Cancer Center at North Shore University Hospital
		Veena S John	Ph: 516-562-3467
	Mineola
	Winthrop University Hospital
		Jeannine A Villella	Ph: 866-946-8476
	New Hyde Park
	Long Island Jewish Medical Center
		Veena S John	Ph: 516-562-3467
	New York
	Beth Israel Medical Center - Petrie Division
		Aliza L Leiser	Ph: 212-844-6286
	Memorial Sloan-Kettering Cancer Center
		Mario M Leitao	Ph: 212-639-7202
	Mount Sinai Medical Center
		Linus T Chuang	Ph: 212-824-7320
			Email: jenny.figueroa@mssm.edu
	St. Luke's - Roosevelt Hospital Center - St.Luke's Division
		Aliza L Leiser	Ph: 212-844-6286
	Rochester
	Daisy Marquis Jones Radiation Oncology Center at Highland Hospital of Rochester
		Yuhchyau Chen	Ph: 585-275-5830
	James P. Wilmot Cancer Center at University of Rochester Medical Center
		Yuhchyau Chen	Ph: 585-275-5830
	Stony Brook
	Stony Brook University Cancer Center
		Michael L. Pearl	Ph: 800-862-2215
	Syracuse
	SUNY Upstate Medical University Hospital
		Mary J Cunningham	Ph: 315-464-5476
	Valhalla
	New York Medical College
		Sean S Tedjarati	Ph: 888-823-5923
			Email: ctsucontact@westat.com
	Westchester Medical Center
		Sean S Tedjarati
			Email: sgriffin@gog.org
North Carolina
	Asheboro
	Randolph Hospital
		Peter Rubin	Ph: 336-832-0821
	Asheville
	Hope A Women's Cancer Center
		Timothy J Vanderkwaak	Ph: 828-670-8403
	Burlington
	Alamance Cancer Center at Alamance Regional Medical Center
		Janak K. Choksi	Ph: 336-538-7725
	Chapel Hill
	Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
		Linda Van Le	Ph: 877-668-0683
	Charlotte
	Blumenthal Cancer Center at Carolinas Medical Center
		Robert Victor Higgins	Ph: 704-355-2884
	Presbyterian Cancer Center at Presbyterian Hospital
		John M McDonald	Ph: 704-384-5369
	Concord
	Batte Cancer Center at Northeast Medical Center
		Robert Victor Higgins	Ph: 704-355-2884
	Durham
	Duke Cancer Institute
		Angeles Alvarez Secord	Ph: 888-275-3853
	Goldsboro
	Wayne Memorial Hospital, Incorporated
		James N. Atkins	Ph: 919-580-0000
	Greensboro
	Moses Cone Regional Cancer Center at Wesley Long Community Hospital
		Peter Rubin	Ph: 336-832-0821
	Pinehurst
	FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center
		John W. Byron	Ph: 910-715-2200
	Raleigh
	Duke Health Raleigh Hospital
		Angeles Alvarez Secord	Ph: 888-275-3853
	Reidsville
	Annie Penn Cancer Center
		Peter Rubin	Ph: 336-832-0821
	Winston-Salem
	Wake Forest University Comprehensive Cancer Center
		Samuel S. Lentz	Ph: 336-713-6771
North Dakota
	Grand Forks
	Altru Cancer Center at Altru Hospital
		Grant R Seeger	Ph: 701-780-6520
Ohio
	Akron
	Summa Center for Cancer Care at Akron City Hospital
		Vivian von Gruenigen	Ph: 330-375-6101
	Canton
	Aultman Cancer Center at Aultman Hospital
		Michael P. Hopkins	Ph: 330-363-6891
	Chillicothe
	Adena Regional Medical Center
		J. Philip Kuebler	Ph: 502-361-8496
	Cincinnati
	University of Cincinnati
		Thomas J. Reid	Ph: 937-298-3399
			Email: uchealthnews@uc.edu
	Cleveland
	Cleveland Clinic Cancer Center at Fairview Hospital
		Peter Graham Rose	Ph: 866-223-8100
	Cleveland Clinic Taussig Cancer Center
		Peter Graham Rose	Ph: 866-223-8100
	MetroHealth Cancer Care Center at MetroHealth Medical Center
		Peter Graham Rose	Ph: 866-223-8100
	Columbus
	Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center
		David Elliot Cohn	Ph: 866-627-7616
			Email: osu@emergingmed.com
	CCOP - Columbus
		J. Philip Kuebler	Ph: 502-361-8496
	Doctors Hospital at Ohio Health
		J. Philip Kuebler	Ph: 502-361-8496
	Grant Medical Center Cancer Care
		J. Philip Kuebler	Ph: 502-361-8496
	Mount Carmel Health - West Hospital
		J. Philip Kuebler	Ph: 502-361-8496
	Riverside Methodist Hospital Cancer Care
		Jeffrey G. Bell	Ph: 614-566-4475
	Zangmeister Center
		J. Philip Kuebler	Ph: 502-361-8496
	Dayton
	David L. Rike Cancer Center at Miami Valley Hospital
		John W Moroney	Ph: 937-208-2079
	Delaware
	Grady Memorial Hospital
		J. Philip Kuebler	Ph: 614-566-3275
	Marietta
	Strecker Cancer Center at Marietta Memorial Hospital
		J. Philip Kuebler	Ph: 502-361-8496
	Mayfield Heights
	Hillcrest Cancer Center at Hillcrest Hospital
		Peter Graham Rose	Ph: 866-223-8100
	Mentor
	Lake/University Ireland Cancer Center
		Steven E. Waggoner	Ph: 800-641-2422
	Newark
	Licking Memorial Cancer Care Program at Licking Memorial Hospital
		J. Philip Kuebler	Ph: 502-361-8496
	Portsmouth
	Southern Ohio Medical Center Cancer Center
		J. Philip Kuebler	Ph: 502-361-8496
	Springfield
	Community Hospital of Springfield and Clark County
		J. Philip Kuebler	Ph: 502-361-8496
	Westerville
	Mount Carmel St. Ann's Cancer Center
		J. Philip Kuebler	Ph: 502-361-8496
	Zanesville
	Genesis - Good Samaritan Hospital
		J. Philip Kuebler	Ph: 502-361-8496
Oklahoma
	Oklahoma City
	Oklahoma University Cancer Institute
		Robert S. Mannel	Ph: 405-271-4272
			Email: julie-traylor@ouhsc.edu
	Tulsa
	Cancer Care Associates-Yale
		Robert S. Mannel	Ph: 405-271-4272
			Email: julie-traylor@ouhsc.edu
Pennsylvania
	Abington
	Rosenfeld Cancer Center at Abington Memorial Hospital
		Parviz Hanjani	Ph: 215-481-2402
	Allentown
	Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
		Richard M. Boulay	Ph: 610-402-2273
	Bethlehem
	St. Luke's Cancer Network at St. Luke's Hospital
		Nicholas P Taylor	Ph: 610-954-3582
			Email: infolink@slhn.org
	Danville
	Geisinger Cancer Institute at Geisinger Health
		James R Bosscher	Ph: 570-271-5251
			Email: ehicks@sprg.mercy.net
	Drexel Hill
	Delaware County Regional Cancer Center at Delaware County Memorial Hospital
		Joel S Noumoff	Ph: 610-447-2654
			Email: colleen.kennedy@crozer.org
	Hershey
	Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center
		James Fanning	Ph: 717-531-3779
			Email: CTO@hmc.psu.edu
	Philadelphia
	Abramson Cancer Center of the University of Pennsylvania
		Stephen C. Rubin	Ph: 215-746-7406
	Fox Chase Cancer Center - Philadelphia
		Sarah H Kim	Ph: 215-728-4790
	Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
		Norman G. Rosenblum	Ph: 215-955-6084
	Temple Cancer Center at Temple University Hospital
		Enrique Hernandez	Ph: 215-728-2983
	Pittsburgh
	UPMC Cancer Centers
		Kristin K Zorn	Ph: 412-647-2811
	Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
		Eileen Segreti	Ph: 412-578-5000
	Upland
	Crozer-Chester Medical Center
		Joel S Noumoff	Ph: 610-447-2654
			Email: colleen.kennedy@crozer.org
	West Reading
	McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center
		Bernice L Robinson-Bennett	Ph: 610-988-9323
	Wilkes-Barre
	Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
		James R Bosscher	Ph: 570-271-5251
			Email: ehicks@sprg.mercy.net
Rhode Island
	Providence
	Women and Infants Hospital of Rhode Island
		Carolyn K McCourt	Ph: 401-274-1122
South Carolina
	Greenville
	Cancer Centers of the Carolinas - Andrews
		Larry E Puls	Ph: 864-241-6251
	Cancer Centers of the Carolinas - Faris Road
		Larry E Puls	Ph: 864-241-6251
	CCOP - Greenville
		Larry E Puls	Ph: 864-241-6251
	Greer
	Cancer Centers of the Carolinas - Greer Radiation Oncology
		Larry E Puls	Ph: 864-241-6251
	Seneca
	Cancer Centers of the Carolinas - Seneca
		Larry E Puls	Ph: 864-241-6251
	Spartanburg
	Cancer Centers of the Carolinas - Spartanburg
		Larry E Puls	Ph: 864-241-6251
South Dakota
	Rapid City
	Black Hills Obstetrics & Gynecology LLP
		Helen L. Frederickson	Ph: 605-343-9224
	Sioux Falls
	Avera Cancer Institute
		Luis A Rojas-Espaillat	Ph: 800-657-4377
			Email: Jan.Healy@avera.org
	Sanford Cancer Center at Sanford USD Medical Center
		Maria C. Bell	Ph: 218-333-5000
		Maria C. Bell	Ph: 218-333-5000
Texas
	Dallas
	Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
		David Scott Miller	Ph: 214-648-7097
	Galveston
	University of Texas Medical Branch
		Lyuba Levine	Ph: 409-772-1950
			Email: clinical.research@utmb.edu
	Houston
	Methodist Hospital
		Daniel E Lehane	Ph: 713-790-2700
Utah
	Cedar City
	Sandra L. Maxwell Cancer Center
		Ross E. Morgan	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
	Murray
	Jon and Karen Huntsman Cancer Center at Intermountain Medical Center
		Ross E. Morgan	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
	Ogden
	Val and Ann Browning Cancer Center at McKay-Dee Hospital Center
		Ross E. Morgan	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
	Provo
	Utah Valley Regional Medical Center - Provo
		Ross E. Morgan	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
	Saint George
	Dixie Regional Medical Center - East Campus
		Ross E. Morgan	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
	Salt Lake City
	Huntsman Cancer Institute at University of Utah
		Theresa L Werner	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
	LDS Hospital
		Ross E. Morgan	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
	Utah Cancer Specialists at UCS Cancer Center
		Ross E. Morgan	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
Vermont
	Burlington
	Fletcher Allen Health Care - Medical Center Campus
		Cheung Wong	Ph: 802-656-8990
Virginia
	Charlottesville
	University of Virginia Cancer Center
		Susan C Modesitt	Ph: 434-243-6143
	Roanoke
	Carilion Clinic Gynecological Oncology
		Dennis R. Scribner	Ph: 540-985-8510
Washington
	Bellingham
	PeaceHealth Medical Group, PC at St. Joseph Hospital
		Benjamin E. Greer	Ph: 206-616-8289
	Bremerton
	Harrison Medical Center
		Benjamin E. Greer	Ph: 206-616-8289
	Olympic Hematology and Oncology
		Benjamin E. Greer	Ph: 206-616-8289
	Everett
	Providence Regional Cancer Partnership
		Benjamin E. Greer	Ph: 206-616-8289
	Mount Vernon
	Skagit Valley Hospital Cancer Care Center
		Benjamin E. Greer	Ph: 206-616-8289
	Poulsbo
	Harrison Poulsbo Hematology and Onocology
		Benjamin E. Greer	Ph: 206-616-8289
	Seattle
	Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
		Benjamin E. Greer	Ph: 206-616-8289
	Group Health Central Hospital
		Benjamin E. Greer	Ph: 206-616-8289
	Pacific Gynecology Specialists
		Benjamin E. Greer	Ph: 206-616-8289
	Seattle Cancer Care Alliance
		Benjamin E. Greer	Ph: 206-616-8289
	Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
		Benjamin E. Greer	Ph: 206-616-8289
	Swedish Cancer Institute at Northwest Hospital & Medical Center
		Benjamin E. Greer	Ph: 206-616-8289
	University Cancer Center at University of Washington Medical Center
		Benjamin E. Greer	Ph: 206-616-8289
	Sequim
	Olympic Medical Cancer Center
		Benjamin E. Greer	Ph: 206-616-8289
	Tacoma
	Franciscan Cancer Center at St. Joseph Medical Center
		Benjamin E. Greer	Ph: 206-616-8289
	MultiCare Regional Cancer Center at Tacoma General Hospital
		Benjamin E. Greer	Ph: 206-616-8289
	Walla Walla
	St. Mary Regional Cancer Center at St. Mary Medical Center
		Benjamin E. Greer	Ph: 206-616-8289
	Wenatchee
	Wenatchee Valley Medical Center
		Benjamin E. Greer	Ph: 206-616-8289
West Virginia
	Huntington
	Edwards Comprehensive Cancer Center at Cabell Huntington Hospital
		Maria-Rosalia B. Tria Tirona	Ph: 304-399-6617
	Wheeling
	Schiffler Cancer Center at Wheeling Hospital
		Jon David Pollock	Ph: 304-243-6442
Wisconsin
	Eau Claire
	Center for Cancer Treatment & Prevention at Sacred Heart Hospital
		Anthony C. Evans	Ph: 715-389-4457
	Marshfield Clinic Cancer Care at Regional Cancer Center
		Anthony C. Evans	Ph: 715-389-4457
	Green Bay
	Green Bay Oncology, Limited at St. Mary's Hospital
		Jonathan E Tammela	Ph: 920-433-8889
	Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
		Jonathan E Tammela	Ph: 920-433-8889
	St. Mary's Hospital Medical Center - Green Bay
		Jonathan E Tammela	Ph: 920-433-8889
	St. Vincent Hospital Regional Cancer Center
		Jonathan E Tammela	Ph: 920-433-8889
	Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
		Dhimant R. Patel	Ph: 800-252-2990
	La Crosse
	Gundersen Lutheran Center for Cancer and Blood
		Kurt Oettel	Ph: 608-775-2385
			Email: cancerctr@gundluth.org
	Madison
	University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
		David M Kushner	Ph: 877-405-6866
	Marshfield
	Marshfield Clinic - Marshfield Center
		Anthony C. Evans	Ph: 715-389-4457
	Saint Joseph's Hospital
		Anthony C. Evans	Ph: 715-389-4457
	Milwaukee
	Aurora Sinai Medical Center
		Ali Mahdavi	Ph: 414-649-5717
			Email: ucstudy@uci.edu
	Froedtert Hospital and Medical College of Wisconsin
		William H Bradley	Ph: 414-805-4380
	Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center
		Scott A Kamelle	Ph: 414-649-7200
	Minocqua
	Marshfield Clinic - Lakeland Center
		Anthony C. Evans	Ph: 715-389-4457
	New Richmond
	Cancer Center of Western Wisconsin
		Joseph W Leach	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Oconomowoc
	Regional Cancer Center at Oconomowoc Memorial Hospital
		Michael A Thompson	Ph: 262-928-7632
	Oconto Falls
	Green Bay Oncology, Limited - Oconto Falls
		Jonathan E Tammela	Ph: 920-433-8889
	Oshkosh
	Vince Lombardi Cancer Clinic - Oshkosh
		Zahid N Dar	Ph: 800-252-2990
	Racine
	All Saints Cancer Center at Wheaton Franciscan Healthcare
		James H. Taylor	Ph: 414-874-4541
			Email: Kelli.holton@wfhc.org
	Rhinelander
	Ministry Medical Group at Saint Mary's Hospital
		Anthony C. Evans	Ph: 715-389-4457
	Stevens Point
	Marshfield Clinic at Saint Michael's Hospital
		Anthony C. Evans	Ph: 715-389-4457
	Saint Michael's Hospital Cancer Center
		Anthony C. Evans	Ph: 715-389-4457
	Sturgeon Bay
	Green Bay Oncology, Limited - Sturgeon Bay
		Jonathan E Tammela	Ph: 920-433-8889
	Summit
	Aurora Medical Center
		Ali Mahdavi	Ph: 414-649-5717
			Email: ucstudy@uci.edu
	Two Rivers
	Vince Lombardi Cancer Clinic - Two Rivers
		Andrew W Yetter	Ph: 800-252-2990
	Waukesha
	Waukesha Memorial Hospital Regional Cancer Center
		Michael A Thompson	Ph: 262-928-7632
	Wausau
	University of Wisconcin Cancer Center at Aspirus Wausau Hospital
		Christopher G Peterson	Ph: 877-405-6866
	West Allis
	Aurora Women's Pavilion of West Allis Memorial Hospital
		Peter Johnson	Ph: 800-252-2990
	Weston
	Diagnostic and Treatment Center
		Anthony C. Evans	Ph: 715-389-4457
	Marshfield Clinic - Weston Center
		Anthony C. Evans	Ph: 715-389-4457
Canada
Quebec
	Montreal
	Montreal General Hospital
		Luis Souhami	Ph: 514-934-1934ext42953
			Email: evelyn.ortega@muhc.mcgill.ca
Republic of Korea
	Seoul
	Asan Medical Center - University of Ulsan College of Medicine
		Joo-Hyun Nam	Ph: irbksh@amc.seoul.kr
	Gangnam Severance Hospital
		Jae-Hoon Kim
			Email: clinical.trial@bms.com
	Korea Cancer Center Hospital
		Moon-Hong Kim	Ph: 011-82-02-9702-114
	Seoul National University Hospital
		Jae W Kim	Ph: 011-82-760-2384
	Suwon
	Ajou University Hospital
		Hee-Sug Ryu	Ph:  031 219-4311~2
Daegu
	Jung-Ku
	Dongsan Medical Center of Keimyung University
		Chi-Heum Cho
			Email: ho@dsmc.or.kr
Gyeonggi-do
	Goyang-si
	National Cancer Center - Korea
		Sang Y Park	Ph: 011-82-760-2384
KOREA
	Seoul
	Samsung Medical Center
		Duk-Soo Bae	Ph: 011-82-1599-3114
Kyeonggi-do
	Seongnam City
	Seoul National University Bundang Hospital
		Kidong Kim	Ph: 011-82-02-9702-114