Clinical Trials (PDQ®)
Phase III Randomized Study of Lymphadenectomy and Adjuvant External Beam Radiotherapy in Patients With Endometrial Cancer. Note: The information about this trial has not been updated by the sponsor/principal investigator/lead organization. Cancer.gov cannot verify the accuracy of the information.
|Phase III||Treatment||Closed||Any age||Other||MRC-ASTEC|
Lymphadenectomy may remove cancer cells that have spread to nearby lymph nodes. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether conventional surgery is more effective with or without lymphadenectomy and/or radiation therapy in treating endometrial cancer.
Eligibility criteria include the following:
- Any age
- For more information about the eligibility criteria for this trial, refer to the Health Professional version.
Final eligibility for a clinical trial is determined by the health professionals conducting the trial.
Patients will be randomly assigned to receive either conventional surgery alone or conventional surgery plus lymphadenectomy and/or radiation therapy. Quality of life will be assessed periodically. Patients will be evaluated every 3 months for 1 year and every 6 months for 1 year.
For more details about this trial, refer to the Health Professional version of the trial summary.
If you are interested in participating in a clinical trial, contact your doctor for a referral or call a trial contact person listed below. You may see the same contact person listed at more than one site, however, if you call the number listed you can ask to speak to the study coordinator or person involved with the specific trial you are interested in. If you have questions about cancer or clinical trials, call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237). General information about clinical trials, including risks, benefits, and costs, can be found on NCI's Web site.
Trial Lead Organizations
Medical Research Council Clinical Trials Unit
|Claire Amos, Study coordinator|
|Official Title||A Randomised Trial of Lymphadenectomy and of Adjuvant External Beam Radiotherapy in the Treatment of Endometrial Cancer|
|Trial Start Date||1998-04-08|
|Registered in ClinicalTrials.gov||NCT00003749|
|Date Submitted to PDQ||1999-01-13|
|Information Last Verified||1999-04-15|