Basic Trial Information
Trial Description
Summary
Further Trial Information
Eligibility Criteria
Trial Contact Information
| Phase | Type | Status | Age | Sponsor | Protocol IDs |
|---|---|---|---|---|---|
| Phase II | Biomarker/Laboratory analysis, Treatment | Active | 18 and over | NCI, Other | CDR0000672523 ECOG-E3108, E3108, NCT01124695 |
Summary
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using tamoxifen citrate may fight cancer by blocking the use of estrogen by tumor cells.
PURPOSE: This phase II trial is studying how well tamoxifen citrate works in patients with metastatic or recurrent breast cancer.
Further Study Information
OBJECTIVES:
Primary
- To correlate CYP2D6 score (0 vs 1-2) and progression-free survival (PFS) of patients with metastatic breast cancer treated with tamoxifen citrate.
Secondary
- To correlate CYP2D6 score (0 vs 1 vs 2) and PFS of patients treated with this regimen.
- To correlate CYP2D6 score (0 vs 1 + 2) and the proportion of these patients who are PFS at 6 months.
- To correlate endoxifen concentration with response in patients treated with this regimen.
- To correlate CYP2D6 with response in patients treated with this regimen.
- To correlate the presence of candidate estrogen receptor (ESR) 1 and 2 variant alleles, UGT7, SULT1A1, and other candidate genes to PFS.
OUTLINE: This is a multicenter study.
Patients receive oral tamoxifen citrate once daily on days 1-28. Treatment repeats every 28 days in the absence of disease progression or unacceptable toxicities.
Blood, plasma, and tissue samples are collected periodically for laboratory studies.
After completion of study therapy, patients are followed up every 3-6 months for 5 years.
Eligibility Criteria
DISEASE CHARACTERISTICS:
- Histologically confirmed adenocarcinoma of the breast
- Stage III (locally advanced), metastatic, or recurrent disease
- Deemed not resectable
- Estrogen-receptor and/or progesterone-receptor positive disease
- Receptor status is based on most recent results
- Receptor testing on metastatic disease is not required
- Measurable or non-measurable disease
- History of CNS metastasis allowed provided it has been treated (surgery, radiotherapy, or radiosurgery) within the past 4 weeks and does not require medications to control symptoms
- No known leptomeningeal disease allowed
PATIENT CHARACTERISTICS:
- ECOG performance status 0-2
- Menopausal status not specified
- Total bilirubin ≤ 1.5 times upper limit of normal (ULN)
- ALT and AST ≤ 2.5 times ULN (≤ 5 times ULN if liver metastases present)
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use effective nonhormonal contraception
- No medical or psychiatric conditions that would interfere with protocol compliance, the ability to provide informed consent, assessment of response, or anticipated toxicities
- More than 5 years since prior invasive malignancies except curatively treated basal cell or squamous cell carcinoma of the skin or carcinoma in situ of the cervix
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
- No prior investigational agents in the metastatic setting
- Other prior investigational agents in any setting must have been completed at least 6 weeks prior to study registration and should be discussed with the study PI
- Prior tamoxifen as adjuvant treatment is allowed as long as the patient did not have disease relapse or progression while on adjuvant tamoxifen or within 4 weeks of last dose
- Prior tamoxifen for advanced disease is not allowed
- No prior chemotherapy or trastuzumab (Herceptin) for metastatic disease
- Prior chemotherapy, trastuzumab, or bevacizumab in the adjuvant setting allowed provided it has been completed ≥ 4 weeks before study therapy
- Patients must not have had more than 2 lines of non-hormonal treatment in the locally advanced or metastatic setting, including trastuzumab (Herceptin), bevacizumab, or other biologics
- Treatment in the advanced setting must have been completed at least 2 weeks prior to study initiation
- Prior aromatase inhibitors (e.g., anastrozole, letrozole, exemestane, aminoglutethamide) are allowed in the adjuvant or metastatic setting
- At least 2 weeks since prior and no concurrent medications that are strong to moderate inhibitors of CYP2D6 and may alter tamoxifen citrate metabolism including, but not limited to, any of the following:
- Paroxetine (Paxil)
- Fluoxetine (Prozac)
- Bupropion (Wellbutrin)
- Quinidine (Cardioquin)
- Patients may not initiate bisphosphonate therapy while receiving treatment on this study
- Patients who have begun receiving bisphosphonate therapy prior to registration may continue at the same intervals used prior to study registration
- Concurrent radiotherapy to painful sites of bone disease or areas of impending fractures allowed provided the following criteria are met:
- Radiotherapy was initiated before study entry
- Sites of measurable or non-measurable disease are outside the radiotherapy port
- Recovered from prior radiotherapy
- No other concurrent hormonal therapy
- No concurrent chemotherapy
Trial Lead Organizations/Sponsors
Eastern Cooperative Oncology Group
National Cancer Institute| Vered Stearns | ![]() | Principal Investigator |
Trial Sites
| U.S.A. | |||
| Alabama | |||
| Birmingham | |||
| UAB Comprehensive Cancer Center | |||
| Carla I. Falkson | Ph: 205-934-0309 | ||
| Mobile | |||
| University of South Alabama Mitchell Cancer Institute | |||
| Windy Dean-Colomb | Ph: 251-445-9870 | ||
| Email: pfrancisco@usouthal.edu | |||
| Arkansas | |||
| Ft. Smith | |||
| Hembree Mercy Cancer Center at St. Edward Mercy Medical Center | |||
| Tony A Flippin | Ph: 800-378-9373 | ||
| California | |||
| Marysville | |||
| Fremont-Rideout Cancer Center | |||
| Helen K. Chew | Ph: 916-734-3089 | ||
| Merced | |||
| Mercy Cancer Center at Mercy Medical Center | |||
| Prasad Pillai | Ph: 916-734-3089 | ||
| Mountain View | |||
| Palo Alto Medical Foundation | |||
| Peter P. Yu | Ph: 650-934-7000 | ||
| Orange | |||
| St. Joseph Hospital Regional Cancer Center - Orange | |||
| Sam S Huang | Ph: 714-734-6220 | ||
| Palo Alto | |||
| Palo Alto Medical Foundation | |||
| David S Leibowitz | Ph: 650-853-2906 | ||
| Email: waldorj@pamf.org | |||
| Sacramento | |||
| University of California Davis Cancer Center | |||
| Helen K. Chew | Ph: 916-734-3089 | ||
| Truckee | |||
| Tahoe Forest Cancer Center | |||
| Helen K. Chew | Ph: 916-734-3089 | ||
| Colorado | |||
| Aurora | |||
| Medical Center of Aurora - South Campus | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Boulder | |||
| Boulder Community Hospital | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Colorado Springs | |||
| Penrose Cancer Center at Penrose Hospital | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Denver | |||
| CCOP - Colorado Cancer Research Program | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Porter Adventist Hospital | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Presbyterian - St. Luke's Medical Center | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Rose Medical Center | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| St. Anthony Central Hospital | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| St. Joseph Hospital | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Englewood | |||
| Swedish Medical Center | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Greeley | |||
| North Colorado Medical Center | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Littleton | |||
| Littleton Adventist Hospital | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Lone Tree | |||
| Sky Ridge Medical Center | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Longmont | |||
| Hope Cancer Care Center at Longmont United Hospital | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Loveland | |||
| McKee Medical Center | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Parker | |||
| Parker Adventist Hospital | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Pueblo | |||
| St. Mary - Corwin Regional Medical Center | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Wheat Ridge | |||
| Exempla Lutheran Medical Center | |||
| Eduardo R. Pajon | Ph: 888-785-6789 | ||
| Connecticut | |||
| Middletown | |||
| Middlesex Hospital Cancer Center | |||
| Susanna Hong | Ph: 860-358-2058 | ||
| Delaware | |||
| Lewes | |||
| Tunnell Cancer Center at Beebe Medical Center | |||
| Gregory A. Masters | Ph: 302-733-6227 | ||
| Newark | |||
| Helen F. Graham Cancer Center at Christiana Hospital | |||
| Gregory A. Masters | Ph: 302-733-6227 | ||
| Florida | |||
| Fort Lauderdale | |||
| Broward General Medical Center Cancer Center | |||
| Archana Maini | Ph: 954-355-5346 | ||
| Hollywood | |||
| Joe DiMaggio Children's Hospital | |||
| Maricer Escalon | Ph: 866-574-5124 | ||
| Email: Sylvester@emergingmed.com | |||
| Georgia | |||
| Columbus | |||
| John B. Amos Cancer Center | |||
| Andrew W. Pippas | Ph: 706-660-6404 | ||
| Savannah | |||
| Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler | |||
| Mark A. Taylor | Ph: 912-350-8568 | ||
| Hawaii | |||
| Aiea | |||
| Kapiolani Medical Center at Pali Momi | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Honolulu | |||
| Cancer Research Center of Hawaii | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Hawaii Medical Center - East | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Kapiolani Medical Center for Women and Children | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| OnCare Hawaii, Incorporated - Kuakini | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| OnCare Hawaii, Incorporated - Lusitana | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Queen's Cancer Institute at Queen's Medical Center | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Straub Clinic and Hospital, Incorporated | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Lihue | |||
| Kauai Medical Clinic | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Wailuku | |||
| Maui Memorial Medical Center | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Pacific Cancer Institute - Maui | |||
| Jeffrey L. Berenberg | Ph: 808-586-2979 | ||
| Illinois | |||
| Chicago | |||
| Louis A. Weiss Memorial Hospital | |||
| Isoken Koko | Ph: 708-488-0882 | ||
| Decatur | |||
| Decatur Memorial Hospital Cancer Care Institute | |||
| James L. Wade | Ph: 217-876-4740 | ||
| Email: kcheek@dmhhs.org | |||
| Elmhurst | |||
| Elmhurst Memorial Hospital | |||
| Lucio Di Nunno | Ph: 630-782-7900 | ||
| River Forest | |||
| West Suburban Center for Cancer Care | |||
| Isoken Koko | Ph: 708-488-0882 | ||
| Indiana | |||
| Elkhart | |||
| Elkhart Clinic, LLC | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Elkhart General Hospital | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Michiana Hematology-Oncology, PC - Elkhart | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Indianapolis | |||
| St. Francis Hospital Cancer Care Services | |||
| Howard M. Gross | Ph: 765-983-3000 | ||
| Kokomo | |||
| Community Cancer Care at Howard Regional Health System | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| La Porte | |||
| Center for Cancer Therapy at LaPorte Hospital and Health Services | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Mishawaka | |||
| Michiana Hematology-Oncology, PC - Mishawaka | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Saint Joseph's Medical Center | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Muncie | |||
| Cancer Center at Ball Memorial Hospital | |||
| Dejuania A Brown | Ph: 765-751-5850 | ||
| Email: alpatterson@medicalconsultantspc.com | |||
| Plymouth | |||
| Michiana Hematology Oncology PC - Plymouth | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Richmond | |||
| Reid Hospital & Health Care Services | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| South Bend | |||
| CCOP - Northern Indiana CR Consortium | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Memorial Hospital of South Bend | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Michiana Hematology-Oncology, PC - South Bend | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Westville | |||
| Michiana Hematology Oncology-PC Westville | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Iowa | |||
| Ames | |||
| McFarland Clinic, PC | |||
| Joseph James Merchant | Ph: 515-239-2621 | ||
| Clive | |||
| Medical Oncology and Hematology Associates-West Des Moines | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| Mercy Cancer Center - West Lakes | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| Des Moines | |||
| CCOP - Iowa Oncology Research Association | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| John Stoddard Cancer Center at Iowa Lutheran Hospital | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| John Stoddard Cancer Center at Iowa Methodist Medical Center | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| Medical Oncology and Hematology Associates at John Stoddard Cancer Center | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| Medical Oncology and Hematology Associates at Mercy Cancer Center | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| Mercy Cancer Center at Mercy Medical Center - Des Moines | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| Sioux City | |||
| Mercy Medical Center - Sioux City | |||
| Donald Bruce Wender | Ph: 712-252-0088 | ||
| Siouxland Hematology-Oncology Associates, LLP | |||
| Donald Bruce Wender | Ph: 712-252-0088 | ||
| St. Luke's Regional Medical Center | |||
| Donald Bruce Wender | Ph: 712-252-0088 | ||
| West Des Moines | |||
| Methodist West Hospital | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| Robert J Behrens | Ph: 888-244-6061 | ||
| Email: sherrijr@iora.org | |||
| Kansas | |||
| Chanute | |||
| Cancer Center of Kansas, PA - Chanute | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Dodge City | |||
| Cancer Center of Kansas, PA - Dodge City | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| El Dorado | |||
| Cancer Center of Kansas, PA - El Dorado | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Fort Scott | |||
| Cancer Center of Kansas - Fort Scott | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Independence | |||
| Cancer Center of Kansas-Independence | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Kingman | |||
| Cancer Center of Kansas, PA - Kingman | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Lawrence | |||
| Lawrence Memorial Hospital | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Liberal | |||
| Cancer Center of Kansas, PA - Liberal | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| McPherson | |||
| Cancer Center of Kansas, PA - McPherson | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Newton | |||
| Cancer Center of Kansas, PA - Newton | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Parsons | |||
| Cancer Center of Kansas, PA - Parsons | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Pratt | |||
| Cancer Center of Kansas, PA - Pratt | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Salina | |||
| Cancer Center of Kansas, PA - Salina | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Wellington | |||
| Cancer Center of Kansas, PA - Wellington | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Wichita | |||
| Associates in Women's Health, PA - North Hillside | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Cancer Center of Kansas, PA - Medical Arts Tower | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Cancer Center of Kansas, PA - Wichita | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| CCOP - Wichita | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Via Christi Cancer Center at Via Christi Regional Medical Center | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Winfield | |||
| Cancer Center of Kansas, PA - Winfield | |||
| Shaker R. Dakhil | Ph: 316-262-4467 | ||
| Maryland | |||
| Baltimore | |||
| Greenebaum Cancer Center at University of Maryland Medical Center | |||
| Katherine Tkaczuk | Ph: 800-888-8823 | ||
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |||
| Vered Stearns | Ph: 410-955-8804 | ||
| Email: jhcccro@jhmi.edu | |||
| Elkton MD | |||
| Union Hospital of Cecil County | |||
| Gregory A. Masters | Ph: 302-733-6227 | ||
| Michigan | |||
| Adrian | |||
| Hickman Cancer Center at Bixby Medical Center | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Ann Arbor | |||
| University of Michigan Comprehensive Cancer Center | |||
| Anne F. Schott | Ph: 800-865-1125 | ||
| Detroit | |||
| Josephine Ford Cancer Center at Henry Ford Hospital | |||
| Robert Anthony Chapman | Ph: 313-916-1784 | ||
| Wayne State University | |||
| Lawrence E. Flaherty | Ph: 313-576-9363 | ||
| Escanaba | |||
| Green Bay Oncology, Limited - Escanaba | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Iron Mountain | |||
| Green Bay Oncology - Iron Mountain | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Kalamazoo | |||
| Borgess Medical Center | |||
| Raymond Sterling Lord | Ph: 269-373-7458 | ||
| Bronson Methodist Hospital | |||
| Raymond Sterling Lord | Ph: 269-373-7458 | ||
| West Michigan Cancer Center | |||
| Raymond Sterling Lord | Ph: 269-373-7458 | ||
| Monroe | |||
| Community Cancer Center of Monroe | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Mercy Memorial Hospital - Monroe | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Saint Joseph | |||
| Lakeside Cancer Specialists, PLLC | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| St. Joseph | |||
| Lakeland Regional Cancer Care Center - St. Joseph | |||
| Jose A. Bufill | Ph: 574-237-1328 | ||
| Minnesota | |||
| Bemidji | |||
| MeritCare Bemidji | |||
| Preston D. Steen | Ph: 701-234-6161 | ||
| Brainerd | |||
| St. Joseph's Medical Center | |||
| Daniel Nikcevich | Ph: 888-203-7267 | ||
| Burnsville | |||
| Fairview Ridges Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Coon Rapids | |||
| Mercy and Unity Cancer Center at Mercy Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Duluth | |||
| CCOP - Duluth | |||
| Daniel Nikcevich | Ph: 888-203-7267 | ||
| Essentia Health - Duluth Clinic | |||
| Daniel Nikcevich | Ph: 888-203-7267 | ||
| Miller - Dwan Medical Center | |||
| Daniel Nikcevich | Ph: 888-203-7267 | ||
| Edina | |||
| Fairview Southdale Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Fridley | |||
| Mercy and Unity Cancer Center at Unity Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Hutchinson | |||
| Hutchinson Area Health Care | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Mankato | |||
| Immanuel St. Joseph's | |||
| Mohmmad J Ranginwala | Ph: 507-385-2929 | ||
| Maplewood | |||
| HealthEast Cancer Care at St. John's Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Minnesota Oncology - Maplewood | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Minneapolis | |||
| Hennepin County Medical Center - Minneapolis | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Virginia Piper Cancer Institute at Abbott - Northwestern Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| New Ulm | |||
| New Ulm Medical Center | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Robbinsdale | |||
| Humphrey Cancer Center at North Memorial Outpatient Center | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Rochester | |||
| Mayo Clinic Cancer Center | |||
| Matthew P. Goetz | Ph: 507-538-7623 | ||
| Saint Louis Park | |||
| CCOP - Metro-Minnesota | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Park Nicollet Cancer Center | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Saint Paul | |||
| Regions Hospital Cancer Care Center | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| United Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Shakopee | |||
| St. Francis Cancer Center at St. Francis Medical Center | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Stillwater | |||
| Lakeview Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Waconia | |||
| Ridgeview Medical Center | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Willmar | |||
| Willmar Cancer Center at Rice Memorial Hospital | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Woodbury | |||
| Minnesota Oncology - Woodbury | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Mississippi | |||
| Jackson | |||
| University of Mississippi Cancer Clinic | |||
| Barbara S Craft | Ph: 601-815-6700 | ||
| Missouri | |||
| Bolivar | |||
| Central Care Cancer Center at Carrie J. Babb Cancer Center | |||
| Robert L Carolla | Ph: 417-269-4520 | ||
| Branson | |||
| Skaggs Cancer Center at Skaggs Regional Medical Center | |||
| Robert L Carolla | Ph: 417-269-4520 | ||
| Cape Girardeau | |||
| Southeast Cancer Center | |||
| Alan Philip Lyss | Ph: 800-392-0936 | ||
| Jefferson City | |||
| Goldschmidt Cancer Center | |||
| Alan Philip Lyss | Ph: 800-392-0936 | ||
| Rolla | |||
| Mercy Clinic Cancer and Hematology - Rolla | |||
| Robert L Carolla | Ph: 417-269-4520 | ||
| Saint Louis | |||
| Missouri Baptist Cancer Center | |||
| Alan Philip Lyss | Ph: 800-392-0936 | ||
| Springfield | |||
| Cancer Research for the Ozarks | |||
| Robert L Carolla | Ph: 417-269-4520 | ||
| Hulston Cancer Center at Cox Medical Center South | |||
| Robert L Carolla | Ph: 417-269-4520 | ||
| St. John's Regional Health Center | |||
| Robert L Carolla | Ph: 417-269-4520 | ||
| Montana | |||
| Billings | |||
| Billings Clinic Cancer Center - 801 N 29th Street | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| CCOP - Montana Cancer Consortium | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Hematology-Oncology Centers of the Northern Rockies - Billings | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| St. Vincent Healthcare Cancer Care Services | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Bozeman | |||
| Bozeman Deaconess Cancer Center | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Butte | |||
| St. James Healthcare Cancer Care | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Great Falls | |||
| Benefis Sletten Cancer Institute | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Helena | |||
| St. Peter's Hospital | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Kalispell | |||
| Kalispell Regional Medical Center | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Missoula | |||
| Montana Cancer Center at St. Patrick Hospital and Health Sciences Center | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Montana Cancer Specialists at Montana Cancer Center | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Nebraska | |||
| Kearney | |||
| Good Samaritan Cancer Center at Good Samaritan Hospital | |||
| George K. Bascom | Ph: 308-865-7963 | ||
| Lincoln | |||
| Cancer Resource Center - Lincoln | |||
| Gamini S. Soori | Ph: 800-253-4368 | ||
| Omaha | |||
| Alegant Health Cancer Center at Bergan Mercy Medical Center | |||
| Gamini S. Soori | Ph: 800-253-4368 | ||
| CCOP - Missouri Valley Cancer Consortium | |||
| Gamini S. Soori | Ph: 800-253-4368 | ||
| Creighton University Medical Center | |||
| Gamini S. Soori | Ph: 800-253-4368 | ||
| Immanuel Medical Center | |||
| Gamini S. Soori | Ph: 800-253-4368 | ||
| Lakeside Hospital | |||
| Gamini S. Soori | Ph: 800-253-4368 | ||
| Nevada | |||
| Las Vegas | |||
| CCOP - Nevada Cancer Research Foundation | |||
| John Allan Ellerton | Ph: 702-731-8274 | ||
| New Jersey | |||
| Camden | |||
| Cancer Institute of New Jersey at Cooper University Hospital - Camden | |||
| Gregory A. Masters | Ph: 302-733-6227 | ||
| Mount Holly | |||
| Virtua Fox Chase Health Cancer Program at Virtua Memorial Hospital Burlington County | |||
| Michael S. Entmacher | Ph: 888-847-8823 | ||
| Paterson | |||
| St. Joseph's Hospital and Medical Center | |||
| Michael Maroules | Ph: 973-754-2909 | ||
| Somerville | |||
| Somerset Medical Center | |||
| Kathleen C Toomey | Ph: 908-685-2481 | ||
| Toms River | |||
| J. Phillip Citta Regional Cancer Center at Community Medical Center | |||
| Sudha Kavuru | Ph: 732-818-3882 | ||
| Voorhees | |||
| Fox Chase Virtua Health Cancer Program at Virtua West Jersey | |||
| Michael S. Entmacher | Ph: 888-847-8823 | ||
| New Mexico | |||
| Albuquerque | |||
| Lovelace Medical Center - Downtown | |||
| Melanie E. Royce | Ph: 505-727-8000 | ||
| University of New Mexico Cancer Center | |||
| Melanie E. Royce | Ph: 505-727-8000 | ||
| Las Cruces | |||
| Memorial Medical Center | |||
| Melanie E. Royce | Ph: 505-727-8000 | ||
| New York | |||
| Bronx | |||
| Jack D. Weiler Hospital at Montefiore Medical Center - East Campus | |||
| Christine M. Pellegrino | Ph: 718-904-2730 | ||
| Email: aecc@aecom.yu.edu | |||
| Montefiore Medical Center | |||
| Christine M. Pellegrino | Ph: 718-904-2730 | ||
| Email: aecc@aecom.yu.edu | |||
| Glens Falls | |||
| Charles R. Wood Cancer Center at Glens Falls Hospital | |||
| Eric A Pillemer | Ph: 518-926-6700 | ||
| New York | |||
| Beth Israel Medical Center - Petrie Division | |||
| Paula Klein | Ph: 212-367-1729 | ||
| St. Luke's - Roosevelt Hospital Center - St.Luke's Division | |||
| Paula Klein | Ph: 212-367-1729 | ||
| North Carolina | |||
| Goldsboro | |||
| Wayne Memorial Hospital, Incorporated | |||
| James N. Atkins | Ph: 919-580-0000 | ||
| Kinston | |||
| Kinston Medical Specialists | |||
| Peter R. Watson | Ph: 252-559-2200 | ||
| North Dakota | |||
| Bismarck | |||
| Medcenter One Hospital Cancer Care Center | |||
| John T Reynolds | Ph: 701-323-5760 | ||
| Email: tfischer@mohs.org | |||
| Mid Dakota Clinic, PC | |||
| John T Reynolds | Ph: 701-323-5760 | ||
| Email: tfischer@mohs.org | |||
| St. Alexius Medical Center Cancer Center | |||
| John T Reynolds | Ph: 701-323-5760 | ||
| Email: tfischer@mohs.org | |||
| Fargo | |||
| Roger Maris Cancer Center at MeritCare Hospital | |||
| Miroslaw A Mazurczak | Ph: 605-328-1367 | ||
| Preston D. Steen | Ph: 701-234-6161 | ||
| Sanford Clinic North-Fargo | |||
| Preston D. Steen | Ph: 701-234-6161 | ||
| Ohio | |||
| Beachwood | |||
| Cleveland Clinic Taussig Cancer Center | |||
| Paula Silverman | Ph: 800-641-2422 | ||
| Bowling Green | |||
| Wood County Oncology Center | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Canton | |||
| Aultman Cancer Center at Aultman Hospital | |||
| Kisa E Weeman | Ph: 330-363-6891 | ||
| Cleveland | |||
| Case Comprehensive Cancer Center | |||
| Paula Silverman | Ph: 800-641-2422 | ||
| Cleveland Clinic Cancer Center at Fairview Hospital | |||
| Paula Silverman | Ph: 800-641-2422 | ||
| Cleveland Clinic Taussig Cancer Center | |||
| Paula Silverman | Ph: 800-641-2422 | ||
| Dayton | |||
| CCOP - Dayton | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| David L. Rike Cancer Center at Miami Valley Hospital | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Good Samaritan Hospital | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Grandview Hospital | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Samaritan North Cancer Care Center | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Elyria | |||
| Hematology Oncology Center | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Mercy Cancer Center - Elyria | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Findlay | |||
| Blanchard Valley Regional Cancer Center | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Franklin | |||
| Atrium Medical Center | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Greenville | |||
| Wayne Hospital | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Independence | |||
| Cleveland Clinic Taussig Cancer Center | |||
| Paula Silverman | Ph: 800-641-2422 | ||
| Kettering | |||
| Charles F. Kettering Memorial Hospital | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Lima | |||
| Lima Memorial Hospital | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Maumee | |||
| Northwest Ohio Oncology Center | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Mayfield Heights | |||
| Hillcrest Cancer Center at Hillcrest Hospital | |||
| Paula Silverman | Ph: 800-641-2422 | ||
| Oregon | |||
| St. Charles Mercy Hospital | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Toledo Clinic - Oregon | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Parma | |||
| Parma Community General Hospital | |||
| Anjali S Advani | Ph: 866-223-8100 | ||
| Sandusky | |||
| North Coast Cancer Care, Incorporated | |||
| Paula Silverman | Ph: 800-641-2422 | ||
| Strongsville | |||
| Cleveland Clinic Foundation - Strongsville | |||
| Anjali S Advani | Ph: 866-223-8100 | ||
| Sylvania | |||
| Flower Hospital Cancer Center | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Tiffin | |||
| Mercy Hospital of Tiffin | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Toledo | |||
| CCOP - Toledo Community Hospital | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| St. Anne Mercy Hospital | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| St. Vincent Mercy Medical Center | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Toledo Clinic, Incorporated - Main Clinic | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Toledo Hospital | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| University of Toledo Medical Center | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Troy | |||
| UVMC Cancer Care Center at Upper Valley Medical Center | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Wauseon | |||
| Fulton County Health Center | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Wooster | |||
| Cleveland Clinic - Wooster | |||
| Paula Silverman | Ph: 800-641-2422 | ||
| Wright-Patterson Afb | |||
| United States Air Force Medical Center - Wright-Patterson | |||
| Brandon J Cutler | Ph: 937-257-1398 | ||
| Xenia | |||
| Ruth G. McMillan Cancer Center at Greene Memorial Hospital | |||
| Howard M. Gross | Ph: 317-783-8918 | ||
| Oklahoma | |||
| Norman | |||
| Cancer Care Associates - Norman | |||
| Vikki Ann Canfield | Ph: 888-823-5923 | ||
| Email: ctsucontact@westat.com | |||
| Oklahoma City | |||
| Cancer Care Associates - Mercy Campus | |||
| Vikki Ann Canfield | Ph: 888-823-5923 | ||
| Email: ctsucontact@westat.com | |||
| Pennsylvania | |||
| Doylestown | |||
| Doylestown Hospital Cancer Center | |||
| Mitchell Alden | Ph: 215-345-2378 | ||
| Email: lheacock@dh.org | |||
| Hershey | |||
| Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center | |||
| Leah v Cream | Ph: 717-531-3779 | ||
| Email: CTO@hmc.psu.edu | |||
| Langhorne | |||
| St. Mary Regional Cancer Center | |||
| Robert C. Reilly | Ph: 215-710-4585 | ||
| Pottstown | |||
| Pottstown Memorial Regional Cancer Center | |||
| Wei Song | Ph: 610-327-7544 | ||
| South Dakota | |||
| Sioux Falls | |||
| Sanford Cancer Center at Sanford USD Medical Center | |||
| Miroslaw A Mazurczak | Ph: 605-328-1367 | ||
| Miroslaw A Mazurczak | Ph: 605-328-1367 | ||
| Texas | |||
| Dallas | |||
| Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas | |||
| Barbara B. Haley | Ph: 214-648-7097 | ||
| Virginia | |||
| Fredericksburg | |||
| Fredericksburg Oncology Inc | |||
| Rex B Mowat | Ph: 517-265-0116 | ||
| Washington | |||
| Anacortes | |||
| Cancer Care Center at Island Hogs | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Bellingham | |||
| St. Joseph Cancer Center | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Bremerton | |||
| Olympic Hematology and Oncology | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Burien | |||
| Highline Medical Center Cancer Center | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Edmonds | |||
| Swedish Cancer Institute at Stevens Hospital | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Issaquah | |||
| Swedish Medical Center - Issaquah Campus | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Kennewick | |||
| Columbia Basin Hematology | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Mount Vernon | |||
| Skagit Valley Hospital Cancer Care Center | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Poulsbo | |||
| Harrison Poulsbo Hematology and Onocology | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Seattle | |||
| Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Group Health Central Hospital | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Harborview Medical Center | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Minor and James Medical, PLLC | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| University Cancer Center at University of Washington Medical Center | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Sedro-Woolley | |||
| North Puget Oncology at United General Hospital | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Spokane | |||
| Cancer Care Northwest - Spokane South | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Evergreen Hematology and Oncology, PS | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| Wenatchee | |||
| Wenatchee Valley Medical Center | |||
| Gary E Goodman | Ph: 206-386-2323 | ||
| Email: patra.grevstad@swedish.org | |||
| West Virginia | |||
| Charleston | |||
| West Virginia University Medical School - Charleston | |||
| Steven J. Jubelirer | Ph: 304-388-9944 | ||
| Wisconsin | |||
| Antigo | |||
| Langlade Memorial Hospital | |||
| Hamied R. Rezazadeh | Ph: 877-405-6866 | ||
| Green Bay | |||
| Green Bay Oncology, Limited at St. Mary's Hospital | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| St. Mary's Hospital Medical Center - Green Bay | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| St. Vincent Hospital Regional Cancer Center | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center | |||
| Dhimant R. Patel | Ph: 800-252-2990 | ||
| La Crosse | |||
| Gundersen Lutheran Center for Cancer and Blood | |||
| Kurt Oettel | Ph: 608-775-2385 | ||
| Email: cancerctr@gundluth.org | |||
| Manitowoc | |||
| Holy Family Memorial Medical Center Cancer Care Center | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Marinette | |||
| Bay Area Cancer Care Center at Bay Area Medical Center | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Vince Lombardi Cancer Clinic - Marinette | |||
| Dhimant R. Patel | Ph: 800-252-2990 | ||
| Mukwonago | |||
| D.N. Greenwald Center | |||
| Michael A Thompson | Ph: 262-928-7632 | ||
| New Richmond | |||
| Cancer Center of Western Wisconsin | |||
| Joseph W Leach | Ph: 952-993-1517 | ||
| Email: MMCCOP@parknicollet.com | |||
| Oconomowoc | |||
| Regional Cancer Center at Oconomowoc Memorial Hospital | |||
| Michael A Thompson | Ph: 262-928-7632 | ||
| Oconto Falls | |||
| Green Bay Oncology, Limited - Oconto Falls | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Oshkosh | |||
| Vince Lombardi Cancer Clinic - Oshkosh | |||
| Dhimant R. Patel | Ph: 800-252-2990 | ||
| Sheboygan | |||
| Saint Nicholas Hospital | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Vince Lombardi Cancer Clinic - Sheboygan | |||
| Dhimant R. Patel | Ph: 800-252-2990 | ||
| Sturgeon Bay | |||
| Green Bay Oncology, Limited - Sturgeon Bay | |||
| Gerald K. Bayer | Ph: 800-432-6049 | ||
| Summit | |||
| Aurora Medical Center | |||
| Dhimant R. Patel | Ph: 800-252-2990 | ||
| Two Rivers | |||
| Vince Lombardi Cancer Clinic - Two Rivers | |||
| Dhimant R. Patel | Ph: 800-252-2990 | ||
| Waukesha | |||
| Waukesha Memorial Hospital Regional Cancer Center | |||
| Michael A Thompson | Ph: 262-928-7632 | ||
| Wausau | |||
| University of Wisconcin Cancer Center at Aspirus Wausau Hospital | |||
| Hamied R. Rezazadeh | Ph: 877-405-6866 | ||
| Wisconsin Rapids | |||
| Riverview UW Cancer Center at Riverview Hospital | |||
| Ron James Kirschling | Ph: 877-405-6866 | ||
| Wyoming | |||
| Casper | |||
| Rocky Mountain Oncology | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Sheridan | |||
| Welch Cancer Center at Sheridan Memorial Hospital | |||
| Benjamin Thomas Marchello | Ph: 800-648-6274 | ||
| Canada | |||
| British Columbia | |||
| Kelowna | |||
| British Columbia Cancer Agency - Centre for the Southern Interior | |||
| Caroline A Lohrisch | Ph: 888-939-3333 | ||
| Vancouver | |||
| British Columbia Cancer Agency - Vancouver Cancer Centre | |||
| Caroline A Lohrisch | Ph: 888-939-3333 | ||
| Peru | |||
| Lima | |||
| Instituto Nacional de Enfermedades Neoplasicas | |||
| Henry L Gomez Moreno | Ph: (511) 710-6900 | ||
Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01124695
Information obtained from ClinicalTrials.gov on December 09, 2012
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