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Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Basic Trial Information
Trial Description
     Summary
     Further Trial Information
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIIHealth services research, TreatmentActive18 and overNCINCI-2011-02623
S1007, CDR0000692475, U10CA032102, SWOG-S1007, NCT01272037

Trial Description

Summary

This phase III clinical trial is studying how well giving tamoxifen citrate, anastrozole, letrozole, or exemestane with or without chemotherapy works in treating patients with invasive breast cancer. Estrogen can cause the growth of breast cancer cells. Hormone therapy, using tamoxifen citrate, may fight breast cancer by blocking the use of estrogen by the tumor cells. Aromatase inhibitors, such as anastrozole, letrozole, and exemestane, may fight breast cancer by lowering the amount of estrogen the body makes. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving tamoxifen citrate, anastrozole, letrozole, or exemestane is more effective with combination chemotherapy in treating patients with breast cancer.

Further Study Information

PRIMARY OBJECTIVES:

I. To determine the effect of endocrine therapy with versus without chemotherapy in patients with node-positive breast cancer who do not have high Recurrence Scores (RS) by Oncotype DX.

SECONDARY OBJECTIVES:

I. To compare overall survival (OS), distant disease-free survival (DDFS), and local disease-free interval (LDFI) by receipt of chemotherapy or not and its interaction with RS. II. To compare the toxicity across the treatment arms. III. To perform other assays or tests (in particular the PAM50 risk of relapse score) as they are developed and validated that measure potential benefit of chemotherapy and compare them to Oncotype DX.

IV. To determine the impact of management with Oncotype DX on patient-reported anxiety (co-primary Health-Related Quality of Life [HRQL] outcome) prior to screening, after disclosure of test results, and during the randomized trial.

V. To determine the impact of Oncotype DX on the initial management cost of node-positive, HR-positive, HER2-negative breast cancer.

VI. To compare patient-reported utilities (e.g., QOL) for those randomized to chemotherapy versus no chemotherapy.

VII. To estimate the cost-effectiveness of management with Oncotype DX vs usual care using modeling and DFS information from the trial.

VIII. To determine the role of other assays (e.g., PAM50) as predictors of DFS, DDFS, and LDFI of patients randomized to chemotherapy versus no chemotherapy.

IX. To determine the impact of treatment with chemotherapy versus no chemotherapy on patient-reported fatigue and cognitive concerns (secondary HRQL outcomes).

X. To determine the impact of management with Oncotype DX on patient-reported decision conflict, perceptions regarding Oncotype DX testing, and survivor concerns prior to screening, after disclosure of test results, and during the randomized trial (secondary HRQL outcomes).

OUTLINE: This is a multicenter study. Patients are stratified according to Recurrence Score (0-13 vs 14-25), menopausal status (pre-menopausal vs post-menopausal), and type of nodal dissection (axillary lymph node dissection [with or without sentinel node mapping] vs sentinel node biopsy without axillary lymph node dissection). Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive a protocol-approved chemotherapy regimen based on the patient and/or physician preference. Patients then receive a protocol-approved adjuvant endocrine therapy comprising tamoxifen citrate, an aromatase inhibitor (anastrozole, letrozole, or exemestane), or both for 5-10 years in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive a protocol-approved endocrine therapy comprising tamoxifen citrate, an aromatase inhibitor (anastrozole, letrozole, or exemestane), or both for 5-10 years in the absence of disease progression or unacceptable toxicity.

Patients may complete health-related quality-of-life (QOL) questionnaires at baseline and periodically during study. Information on Medicare and/or insurance coverage and on health coverage decisions may also be collected periodically.

After completion of study therapy, patients are followed up every 3 months for 2 years, every 6 months for 3 years, and then yearly for at least 15 years.

Eligibility Criteria

Inclusion Criteria:

  • Patients must have a histologically confirmed diagnosis of node positive (1-3 nodes) invasive breast carcinoma with positive estrogen and/or progesterone receptor status, and negative HER-2, as determined by IHC or gene amplification evaluation (e.g. FISH, CISH, etc.); estrogen and progesterone receptor positivity must be assessed according to ASCO/CAP guidelines as either ER or PR >= 1% positive nuclear staining; if HER2 IHC is 2+, an evaluation for gene amplification must be performed and must not be amplified, but otherwise gene amplification evaluation is not required if IHC is 0 or 1+ by institutional standards
  • Patients must not have inflammatory breast cancer and must not have metastatic disease; patients with a prior diagnosis of DCIS are eligible if they received mastectomy alone (no therapeutic radiation, intraoperative radiation, or endocrine therapy); radiation in the opposite breast is acceptable
  • Must have had breast-conserving surgery with planned radiotherapy or total mastectomy (with or without planned post mastectomy radiation) with clear margins within the past 28-84 days
  • Menopausal status: pre- or post-menopausal
  • Zubrod performance status 0-2
  • Not pregnant or nursing
  • Fertile patients must use an effective non-hormonal contraception method while on treatment and for ≥ 3 months after completion of protocol treatment
  • No other prior malignancy except adequately treated basal cell or squamous cell skin cancer; in situ cervical cancer; adequately treated stage 0, I, or II cancer from which the patient is currently in complete remission; or any other cancer from which the patient has been disease-free for the past 5 years
  • LVEF ≥ 50% if an anthracycline-based regimen is planned
  • Patients randomized to chemotherapy may also co-enroll in Phase III trials that compare chemotherapies
  • No prior chemotherapy or endocrine therapy for breast cancer
  • No prior preventive tamoxifen or raloxifene
  • No prior therapeutic breast radiotherapy
  • Not requiring concurrent chronic treatment with systemic steroids or other immunosuppressive agents
  • Patients randomized to either arm may also co-enroll in Phase III trials that compare local therapies or compare systemic therapies (not including chemotherapy)
  • Patients with multifocal, multicentric and synchronous bilateral breast cancers are allowed
  • Multifocal disease is defined as more than one invasive cancer < 2 cm from the largest lesion within the same breast quadrant; (NOTE: The Oncotype DX testing must be completed on the largest lesion)
  • Multicentric disease is defined as more than one invasive cancer ≥ 2 cm from the largest lesion within the same breast quadrant or more than one lesion in different quadrants; (NOTE: Oncotype DX testing should be completed on all tumors and the determination for eligibility should be made on the highest recurrence score)
  • Synchronous bilateral disease is defined as invasive breast cancer with positive lymph nodes (axillary or intramammary) in at least one breast, diagnosed within 30 days of each other; (NOTE: The Oncotype DX testing should be completed on both tumors and the tumor with the highest recurrence score should be used)
  • Patients must be able to receive taxane and/or anthracycline based chemotherapy
  • The Quality of Life and Economic Substudy is permanently closed to accrual effective 12/1/12; patients who are able to complete a questionnaire in English must be offered the opportunity to participate in the Quality of Life and Economic Substudy. (The Quality of Life and Economic Substudy is available to U.S. INSTITUTIONS ONLY); patients who are not able to complete a questionnaire in English are registered to S1007 without participating in the Quality of Life and Economic Substudy
  • Patients who consent to participate in the Quality of Life and Economic Substudy and who do not yet know the results of their Oncotype DX screening must agree to complete the S1007 Health-Related Quality of Life Questionnaire: Enrollment between 14 days prior to and 7 days after Step 1 Registration
  • Patients who consent to participate in the Quality of Life and Economic Substudy and who do already know their Oncotype DX Recurrence Score (and it is 25 or less) will proceed to Step 2 Registration without completing the S1007 Health-Related Quality of Life Questionnaire Enrollment Form (but will complete the S1007 Health-Related Quality of Life Questionnaire: Randomized Study Form)
  • Patients or their legally authorized representative must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines; for Step 1 registration of patients who have not yet submitted specimens for the Oncotype DX Breast Cancer Assay, the appropriate consent form is the Step 1 Consent Form; for both Step 1 and Step 2 registration of patients whose Recurrence Score is already known and is 25 or less, the appropriate consent form is the Step 2 Consent Form

Trial Contact Information

Trial Lead Organizations/Sponsors

National Cancer Institute

Ana Maria Gonzalez-AnguloPrincipal Investigator

Trial Sites

U.S.A.
Alaska
  Anchorage
 Providence Cancer Center
 Jeanne E. Anderson Ph: 907-261-3109
  Fairbanks
 Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital
 Craig R. Nichols Ph: 503-215-6412
Arkansas
  Ft. Smith
 Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
 John Dalie Wells Ph: 800-378-9373
California
  Anaheim
 Kaiser Permanente Medical Center - Anaheim/Orange County
 Han A Koh Ph: 626-564-3455
  Antioch
 Kaiser Permanente - Deer Valley
 Louis Fehrenbacher Ph: 626-564-3455
  Baldwin Park
 Kaiser Permanente Medical Center - Baldwin Park
 Han A Koh Ph: 626-564-3455
  Bellflower
 Kaiser Permanente Medical Center - Bellflower
 Han A Koh Ph: 626-564-3455
  Burbank
 Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center
 Raul R. Mena Ph: 818-847-3220
  Castro Valley
 East Bay Radiation Oncology Center
 James H. Feusner Ph: 510-450-7600
 Valley Medical Oncology Consultants - Castro Valley
 James H. Feusner Ph: 510-450-7600
  Duarte
 City of Hope Comprehensive Cancer Center
 Joanne E. Mortimer Ph: 800-826-4673
  Email: becomingapatient@coh.org
  Fairfield
 North Bay Cancer Center
 Brian G Vikstrom Ph: 707-646-4016
  Fontana
 Kaiser Permanente Medical Center - Fontana
 Han A Koh Ph: 626-564-3455
  Fremont
 Kaiser Permanente - Fremont
 Louis Fehrenbacher Ph: 626-564-3455
 Valley Medical Oncology
 James H. Feusner Ph: 510-450-7600
 Washington Township Hospital
 Vandana B Sharma Ph: 510-745-6433
  Fresno
 California Cancer Center - Woodward Park Office
 Dina Ibrahim Ph: 559-447-4050
  Harbor City
 Kaiser Permanente Medical Center - Harbor City
 Han A Koh Ph: 626-564-3455
  Hayward
 Kaiser Permanente Medical Center - Hayward
 Louis Fehrenbacher Ph: 626-564-3455
  Irvine
 Kaiser Permanente - Irvine
 Han A Koh Ph: 626-564-3455
  Loma Linda
 Loma Linda University Cancer Institute at Loma Linda University Medical Center
 Yuan Yuan Ph: 909-558-3375
  Long Beach
 Todd Cancer Institute at Long Beach Memorial Medical Center
 Bichlien Nguyen Ph: 562-933-0900
  Los Angeles
 Kaiser Foundation Hospital - West Los Angeles
 Han A Koh Ph: 626-564-3455
 USC/Norris Comprehensive Cancer Center and Hospital
 Debasish Tripathy Ph: 323-865-0451
  Martinez
 Contra Costa Regional Medical Center
 James H. Feusner Ph: 510-450-7600
  Marysville
 Fremont-Rideout Cancer Center
 Helen K. Chew Ph: 916-734-3089
  Modesto
 Kaiser Permanente-Modesto
 Louis Fehrenbacher Ph: 626-564-3455
 Memorial Medical Center
 Jorge A Garcia-Young Ph: 209-572-7116
  Mountain View
 El Camino Hospital Cancer Center
 James H. Feusner Ph: 510-450-7600
 Palo Alto Medical Foundation
 Peter P. Yu Ph: 650-934-7000
  Northridge
 Northridge Hospital Medical Center
 Sheldon J. Davidson Ph: 818-885-5458
  Oakland
 Alta Bates Summit Medical Center - Summit Campus
 James H. Feusner Ph: 510-450-7600
 Bay Area Breast Surgeons, Incorporated
 James H. Feusner Ph: 510-450-7600
 CCOP - Bay Area Tumor Institute
 James H. Feusner Ph: 510-450-7600
 Highland General Hospital
 James H. Feusner Ph: 510-450-7600
 Kaiser Permanente-Oakland
 Louis Fehrenbacher Ph: 626-564-3455
 Larry G Strieff MD Medical Corporation
 James H. Feusner Ph: 510-450-7600
  Orange
 Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center
 Rita S. Mehta Ph: 877-827-8839
  Email: ucstudy@uci.edu
 St. Joseph Hospital Regional Cancer Center - Orange
 Jay K. Harness Ph: 714-734-6220
  Palo Alto
 Palo Alto Medical Foundation
 David S Leibowitz Ph: 650-853-2906
  Email: waldorj@pamf.org
  Panorama City
 Kaiser Permanente Medical Group
 Han A Koh Ph: 626-564-3455
  Pomona
 Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center
 Yallapragada S. Rao Ph: 909-865-9555
  Redwood City
 Kaiser Permanente Medical Center - Redwood City
 Louis Fehrenbacher Ph: 626-564-3455
  Richmond
 Kaiser Permanente Medical Center - Richmond
 Louis Fehrenbacher Ph: 626-564-3455
  Riverside
 Kaiser Permanente Medical Center - Riverside
 Han A Koh Ph: 626-564-3455
  Roseville
 Kaiser Permanente Medical Center - Roseville
 Louis Fehrenbacher Ph: 626-564-3455
  Sacramento
 Kaiser Permanente Medical Center - Sacramento
 Louis Fehrenbacher Ph: 626-564-3455
 South Sacramento Kaiser-Permanente Medical Center
 Louis Fehrenbacher Ph: 626-564-3455
 University of California Davis Cancer Center
 Helen K. Chew Ph: 916-734-3089
  San Diego
 Kaiser Permanente Medical Center - Kaiser Foundation Hospital - San Diego
 Han A Koh Ph: 626-564-3455
 Kaiser Permanente Medical Office -Vandever Medical Office
 Han A Koh Ph: 626-564-3455
 Sharp Memorial Hospital Cancer Center
 Robert M. Barone Ph: 858-939-5015
  San Francisco
 Kaiser Permanente Medical Center - San Francisco Geary Campus
 Louis Fehrenbacher Ph: 626-564-3455
  San Jose
 Kaiser Permanente Medical Center - Santa Teresa
 Louis Fehrenbacher Ph: 626-564-3455
  San Marcos
 Kaiser Permanente Health Care
 Han A Koh Ph: 626-564-3455
  San Pablo
 Doctors Medical Center - San Pablo Campus
 James H. Feusner Ph: 510-450-7600
  San Rafael
 Kaiser Foundation Hospital - San Rafael
 Louis Fehrenbacher Ph: 626-564-3455
  Santa Clara
 Kaiser Permanente Medical Center - Santa Clara Homestead Campus
 Louis Fehrenbacher Ph: 626-564-3455
  Santa Rosa
 Kaiser Permanente Medical Center - Santa Rosa
 Louis Fehrenbacher Ph: 626-564-3455
  South San Francisco
 Kaiser Permanente Medical Center - South San Francisco
 Louis Fehrenbacher Ph: 626-564-3455
  Stockton
 Kaiser Permanente Medical Facility - Stockton
 Louis Fehrenbacher Ph: 626-564-3455
  Sylmar
 Olive View - UCLA Medical Center Foundation
 Nancy R Feldman Ph: 818-364-1555
  Vacaville
 Kaiser Permanente Medical Center - Vacaville
 Louis Fehrenbacher Ph: 626-564-3455
  Vallejo
 Kaiser Permanente Medical Center - Vallejo
 Louis Fehrenbacher Ph: 626-564-3455
  Walnut Creek
 Kaiser Permanente Medical Center - Walnut Creek
 Louis Fehrenbacher Ph: 626-564-3455
  Woodland Hills
 Kaiser Permanente Medical Cener - Woodland Hills
 Han A Koh Ph: 626-564-3455
Colorado
  Aurora
 Medical Center of Aurora - South Campus
 Eduardo R. Pajon Ph: 888-785-6789
 University of Colorado Cancer Center at UC Health Sciences Center
 Anthony D. Elias Ph: 720-848-0650
  Boulder
 Boulder Community Hospital
 Eduardo R. Pajon Ph: 888-785-6789
  Colorado Springs
 Memorial Hospital Cancer Center - Colorado Springs
 Dax Kurbegov Ph: 719-365-2406
 Penrose Cancer Center at Penrose Hospital
 Eduardo R. Pajon Ph: 888-785-6789
  Denver
 CCOP - Colorado Cancer Research Program
 Eduardo R. Pajon Ph: 888-785-6789
 Kaiser Permanente of Colorado
 Alexander Menter Ph: 303-614-1300
 Porter Adventist Hospital
 Eduardo R. Pajon Ph: 888-785-6789
 Presbyterian - St. Luke's Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
 Rose Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
 St. Anthony Central Hospital
 Eduardo R. Pajon Ph: 888-785-6789
 St. Joseph Hospital
 Eduardo R. Pajon Ph: 888-785-6789
  Edwards
 Shaw Regional Cancer Center
 Anthony D. Elias Ph: 720-848-0650
  Englewood
 Swedish Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
  Fort Collins
 Front Range Cancer Specialists
 Diana C. Medgyesy Ph: 970-212-7600
 Poudre Valley Hospital
 Paolo Romero Ph: 970-495-8226
  Glenwood Springs
 Valley View Hospital Cancer Center
 Anthony D. Elias Ph: 720-848-0650
  Grand Junction
 St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
 Anthony D. Elias Ph: 720-848-0650
  Greeley
 North Colorado Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
  Lafayette
 Kaiser Permanente - Lafayette
 Alexander Menter Ph: 303-614-1300
  Littleton
 Littleton Adventist Hospital
 Eduardo R. Pajon Ph: 888-785-6789
  Lone Tree
 Sky Ridge Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
  Longmont
 Hope Cancer Care Center at Longmont United Hospital
 Eduardo R. Pajon Ph: 888-785-6789
  Loveland
 McKee Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
  Montrose
 Montrose Memorial Hospital Cancer Center
 Anthony D. Elias Ph: 720-848-0650
  Parker
 Parker Adventist Hospital
 Eduardo R. Pajon Ph: 888-785-6789
  Pueblo
 St. Mary - Corwin Regional Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
  Thornton
 North Suburban Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
  Wheat Ridge
 Exempla Lutheran Medical Center
 Eduardo R. Pajon Ph: 888-785-6789
Connecticut
  Danbury
 Praxair Cancer Center at Danbury Hospital
 Robert A. Kloss Ph: 203-739-8074
  Hartford
 Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
 Philip J. Stella Ph: 734-712-3456
  Middletown
 Middlesex Hospital Cancer Center
 Susanna Hong Ph: 860-358-2058
  New Haven
 Yale Cancer Center
 Erin W Hofstatter Ph: 203-785-5702
  Norwalk
 Norwalk Hospital
 Richard C. Frank Ph: 203-852-2996
  Email: jennifer.long@norwalkhealth.org
Delaware
  Lewes
 Tunnell Cancer Center at Beebe Medical Center
 Stephen Scott Grubbs Ph: 302-733-6227
  Newark
 Helen F. Graham Cancer Center at Christiana Hospital
 Stephen Scott Grubbs Ph: 302-733-6227
District of Columbia
  Washington
 George Washington University Cancer Institute
 Rebecca D. Kaltman Ph: 202-741-2981
 Sibley Memorial Hospital
 Frederick Pearson Smith Ph: 202-243-2373
Florida
  Fort Lauderdale
 Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
 Michael Schwartz Ph: 305-674-2625
  Email: info@msccop.com
  Jacksonville
 St. Vincent's Medical Center
 Joel A. Stone Ph: 904-538-3667
  Jupiter
 Ella Milbank Foshay Cancer Center at Jupiter Medical Center
 Michael Schwartz Ph: 305-674-2625
  Email: info@msccop.com
  Miami
 Advanced Medical Specialties
 Sara M Garrido Ph: 800-599-2456
  Email: cancerinfo@baptisthealth.net
 Baptist-South Miami Regional Cancer Program
 Sara M Garrido Ph: 800-599-2456
  Email: cancerinfo@baptisthealth.net
 University of Miami Sylvester Comprehensive Cancer Center - Miami
 Mohammad Jahanzeb Ph: 866-574-5124
  Email: Sylvester@emergingmed.com
  Miami Beach
 CCOP - Mount Sinai Medical Center
 Michael Schwartz Ph: 305-674-2625
  Email: info@msccop.com
  Orlando
 M.D. Anderson Cancer Center at Orlando
 Nikita C. Shah Ph: 321-841-7246
  Pensacola
 Sacred Heart Cancer Center at Sacred Heart Hospital
 Tarek Eldawy (Mohamed) Ph: 850-416-6316
  Email: ttamayo@shhpens.org
 Sacred Heart Medical Oncology Group
 Tarek Eldawy (Mohamed) Ph: 850-416-6316
  Email: ttamayo@shhpens.org
Georgia
  Albany
 Phoebe Cancer Center at Phoebe Putney Memorial Hospital
 Robert F. Krywicki Ph: 229-312-2251
  Atlanta
 CCOP - Atlanta Regional
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
 Northside Hospital Cancer Center
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
 Piedmont Hospital
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
 Saint Joseph's Hospital of Atlanta
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
  Augusta
 Medical College of Georgia Cancer Center
 Anand P. Jillella Ph: 706-721-1663
  Email: cancer@georgiahealth.edu
  Austell
 WellStar Cobb Hospital
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
  Decatur
 Charles B. Eberhart Cancer Center at DeKalb Medical Center
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
  Dublin
 Dublin Hematology and Oncology Care
 Anand P. Jillella Ph: 706-721-1663
  Email: cancer@georgiahealth.edu
  Gainesville
 Northeast Georgia Medical Center
 Charles H. Nash Ph: 770-219-8800
  Email: cancerpatient.navigator@nghs.com
  Lawrenceville
 Gwinnett Medical Center
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
  Marietta
 Kennestone Cancer Center at Wellstar Kennestone Hospital
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
  Riverdale
 Southern Regional Medical Center
 Thomas E. Seay Ph: 404-303-3355
  Rome
 Harbin Clinic Cancer Center - Medical Oncology
 Thomas E. Seay Ph: 678-843-7119
  Email: kpackard@sjha.org
  Valdosta
 Pearlman Comprehensive Cancer Center at South Georgia Medical Center
 Jeffrey M. Hoy Ph: 229-259-4628
  Email: maryann.heddon@sgmc.org
Hawaii
  Aiea
 Kapiolani Medical Center at Pali Momi
 Jeffrey L. Berenberg Ph: 808-586-2979
 Jeffrey L. Berenberg Ph: 808-586-2979
  Honolulu
 Cancer Research Center of Hawaii
 Jeffrey L. Berenberg Ph: 808-586-2979
 Hawaii Medical Center - East
 Jeffrey L. Berenberg Ph: 808-586-2979
 Kaiser Permanente - Moanalua Medical Center and Clinic
 Louis Fehrenbacher Ph: 626-564-3455
 Kapiolani Medical Center for Women and Children
 Jeffrey L. Berenberg Ph: 808-586-2979
 OnCare Hawaii, Incorporated - Kuakini
 Jeffrey L. Berenberg Ph: 808-586-2979
 OnCare Hawaii, Incorporated - Lusitana
 Jeffrey L. Berenberg Ph: 808-586-2979
 Queen's Cancer Institute at Queen's Medical Center
 Jeffrey L. Berenberg Ph: 808-586-2979
 Straub Clinic and Hospital, Incorporated
 Jeffrey L. Berenberg Ph: 808-586-2979
 Tripler Army Medical Center
 Jeffrey L. Berenberg Ph: 808-586-2979
  Kailua
 Castle Medical Center
 Jeffrey L. Berenberg Ph: 808-586-2979
  Lihue
 Kauai Medical Clinic
 Jeffrey L. Berenberg Ph: 808-586-2979
  Wailuku
 Maui Memorial Medical Center
 Jeffrey L. Berenberg Ph: 808-586-2979
 Pacific Cancer Institute - Maui
 Jeffrey L. Berenberg Ph: 808-586-2979
Idaho
  Boise
 Mountain States Tumor Institute at St. Luke's Regional Medical Center
 Paul G. Montgomery Ph: 800-845-4624
Illinois
  Bloomington
 St. Joseph Medical Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Bloomington%
 Illinois CancerCare - Bloomington
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Canton
 Illinois CancerCare - Canton
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Carthage
 Illinois CancerCare - Carthage
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Chicago
 Louis A. Weiss Memorial Hospital
 Keith L. Shulman Ph: 773-564-5044
 Robert H. Lurie Comprehensive Cancer Center at Northwestern University
 Virginia G Kaklamani Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Decatur
 Decatur Memorial Hospital Cancer Care Institute
 James L. Wade Ph: 217-876-4740
  Email: kcheek@dmhhs.org
  Elmhurst
 Elmhurst Memorial Hospital
 Lucio Di Nunno Ph: 630-782-7900
  Eureka
 Eureka Community Hospital
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois CancerCare - Eureka
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Freeport
 Leonard C. Ferguson Cancer Center
 Arshad R Shaikh Ph: 815-599-7000
  Galesburg
 Galesburg Clinic, PC
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Harvey
 Ingalls Cancer Care Center at Ingalls Memorial Hospital
 Mark F. Kozloff Ph: 708-915-4673
  Email: clinicaltrials@ingalls.org
  Havana
 Illinois CancerCare - Havana
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Highland Park
 Hematology Oncology Associates of Illinois-Highland Park
 Virginia G Kaklamani Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Kankakee
 Provena St. Mary's Regional Cancer Center - Kankakee
 Virginia G Kaklamani Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Kewanee
 Illinois CancerCare - Kewanee Clinic
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Libertyville
 North Shore Oncology and Hematology Associates, Limited - Libertyville
 Virginia G Kaklamani Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Macomb
 Illinois CancerCare - Macomb
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Maywood
 Cardinal Bernardin Cancer Center at Loyola University Medical Center
 Deepak Malhotra Ph: 708-226-4357
  Moline
 Garneau, Stewart C MD (UIA Investigator)
 Costas L. Constantinou Ph: 319-363-2690
 Porubcin, Michael MD (UIA Investigator)
 Costas L. Constantinou Ph: 319-363-2690
 Spector, David MD (UIA Investigator)
 Costas L. Constantinou Ph: 319-363-2690
 Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
 Costas L. Constantinou Ph: 319-363-2690
  Monmouth
 Illinois CancerCare - Monmouth
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 OSF Holy Family Medical Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Mt. Vernon
 Good Samaritan Regional Health Center
 Bethany G. Sleckman Ph: 913-948-5588
  Naperville
 Hematology Oncology Consultants - Naperville
 Fariborze Behram Barhamand Ph: 630-369-1501
  Niles
 Cancer Care and Hematology Specialists of Chicagoland - Niles
 Virginia G Kaklamani Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Normal
 BroMenn Regional Medical Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Community Cancer Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois CancerCare - Community Cancer Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Mid-Illinois Hematology-Oncology Associates at Community Cancer Center
 John J. Migas Ph: 309-452-9701
  Oak Lawn
 Advocate Christ Medical Center
 Renee H. Jacobs Ph: 630-856-7526
  Ottawa
 Community Hospital of Ottawa
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois CancerCare - Ottawa
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Park Ridge
 Advocate Lutheran General Cancer Care Center
 Jacob D. Bitran Ph: 847-384-3621
  Pekin
 Cancer Treatment Center at Pekin Hospital
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois CancerCare - Pekin
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Peoria
 CCOP - Illinois Oncology Research Association
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois CancerCare - Peoria
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Methodist Medical Center of Illinois
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 OSF St. Francis Medical Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Proctor Hospital
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Peru
 Illinois CancerCare - Princeton
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois Valley Community Hospital
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Princeton
 Illinois CancerCare - Princeton
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  River Forest
 West Suburban Center for Cancer Care
 Isoken Koko Ph: 708-488-0882
  Rockford
 Swedish-American Regional Cancer Center
 Harvey Eric Einhorn Ph: 815-489-4413
  Skokie
 Hematology Oncology Associates - Skokie
 Virginia G Kaklamani Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Spring Valley
 Illinois CancerCare - Spring Valley
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Springfield
 Regional Cancer Center at Memorial Medical Center
 James L. Wade Ph: 217-876-4740
  Email: kcheek@dmhhs.org
Indiana
  Elkhart
 Elkhart Clinic, LLC
 Robin Zon Ph: 574-234-5123
 Elkhart General Hospital
 Robin Zon Ph: 574-234-5123
 Michiana Hematology-Oncology, PC - Elkhart
 Robin Zon Ph: 574-234-5123
  Kokomo
 Community Cancer Care at Howard Regional Health System
 Robin Zon Ph: 574-234-5123
  La Porte
 Center for Cancer Therapy at LaPorte Hospital and Health Services
 Robin Zon Ph: 574-234-5123
  Lafayette
 Clarian Arnett Cancer Care
 Thomas Isaac Jones Ph: 800-899-8448ext7431
  Email: sstidham@clarianarnett.com
  Mishawaka
 Michiana Hematology-Oncology, PC - Mishawaka
 Robin Zon Ph: 574-234-5123
 Saint Joseph's Medical Center
 Robin Zon Ph: 574-234-5123
  Plymouth
 Michiana Hematology Oncology PC - Plymouth
 Robin Zon Ph: 574-234-5123
  Richmond
 Reid Hospital & Health Care Services
 Howard M. Gross Ph: 317-783-8918
  South Bend
 CCOP - Northern Indiana CR Consortium
 Robin Zon Ph: 574-234-5123
 Memorial Hospital of South Bend
 Robin Zon Ph: 574-234-5123
 Michiana Hematology-Oncology, PC - South Bend
 Robin Zon Ph: 574-234-5123
  Westville
 Michiana Hematology Oncology-PC Westville
 Robin Zon Ph: 574-234-5123
Iowa
  Ames
 McFarland Clinic, PC
 Joseph James Merchant Ph: 515-239-2621
  Bettendorf
 Constantinou, Costas L MD (UIA Investigator)
 Costas L. Constantinou Ph: 319-363-2690
  Cedar Rapids
 Iowa Blood and Cancer Care
 David O. Zenk Ph: 319-297-2900
  Email: cetscheidt@pcofiowa.com
 Mercy Regional Cancer Center at Mercy Medical Center
 David O. Zenk Ph: 319-297-2900
  Email: cetscheidt@pcofiowa.com
 St. Luke's Hospital
 David O. Zenk Ph: 319-297-2900
  Email: cetscheidt@pcofiowa.com
  Clive
 Medical Oncology and Hematology Associates-West Des Moines
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Mercy Cancer Center - West Lakes
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
  Council Bluffs
 Heartland Oncology and Hematology
 John A. Okerbloom Ph: 712-322-4136
  Des Moines
 CCOP - Iowa Oncology Research Association
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 John Stoddard Cancer Center at Iowa Lutheran Hospital
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 John Stoddard Cancer Center at Iowa Methodist Medical Center
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Medical Oncology and Hematology Associates at John Stoddard Cancer Center
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Medical Oncology and Hematology Associates at Mercy Cancer Center
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Mercy Cancer Center at Mercy Medical Center - Des Moines
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
  Mason City
 Mercy Cancer Center at Mercy Medical Center - North Iowa
 Arvind Y Vemula Ph: 800-433-3883
  Ottumwa
 South Iowa Radiation Oncology Center at Ottumwa Regional Health Center
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
  Sioux City
 Mercy Medical Center - Sioux City
 Donald Bruce Wender Ph: 712-252-0088
 Siouxland Hematology-Oncology Associates, LLP
 Donald Bruce Wender Ph: 712-252-0088
 St. Luke's Regional Medical Center
 Donald Bruce Wender Ph: 712-252-0088
  Waterloo
 Covenant Cancer Treatment Center
 Mohammed T. Masri Ph: 319-272-2070
  West Des Moines
 Methodist West Hospital
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
Kansas
  Hays
 Hays Medical Center
 Peter J. VanVeldhuizen Ph: 800-525-1483
  Hutchinson
 Hutchinson Hospital Corporation
 Peter J. VanVeldhuizen Ph: 800-525-1483
  Kansas City
 Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
 Peter J. VanVeldhuizen Ph: 800-525-1483
  Lawrence
 Lawrence Memorial Hospital
 Shaker R. Dakhil Ph: 316-262-4467
  Pittsburg
 Mount Carmel Regional Cancer Center
 Peter J. VanVeldhuizen Ph: 800-525-1483
  Salina
 Tammy Walker Cancer Center at Salina Regional Health Center
 Peter J. VanVeldhuizen Ph: 800-525-1483
  Topeka
 St. Francis Comprehensive Cancer Center
 Peter J. VanVeldhuizen Ph: 800-525-1483
  Wichita
 Wesley Medical Center
 Shaker R. Dakhil Ph: 316-262-4467
Kentucky
  Ashland
 Cancer Resource Center at King's Daughters Medical Center
 David K. Goebel Ph: 888-823-5923
  Email: ctsucontact@westat.com
  Lexington
 Central Baptist Hospital
 Lee G. Hicks Ph: 859-260-6425
 University of Kentucky Chandler Medical Center
 Suleiman A Massarweh Ph: 859-257-3379
  Louisville
 University of Louisville School of Medicine
 Dharamvir Jain Ph: 866-530-5516
Louisiana
  Alexandria
 Cabrini Center for Cancer Care at Christus St. Frances Cabrini Hospital
 Gary V Burton Ph: 318-813-1412
  Baton Rouge
 Hematology-Oncology Clinic
 Hana F Safah Ph: 504-988-6121
 Mary Bird Perkins Cancer Center - Baton Rouge
 Robert W Veith Ph: 504-568-3410
  Email: aconne1@lsuhsc.edu
 Ochsner Health Center - Bluebonnet
 Greg A Bizette Ph: 985-871-2549
  Covington
 Ochsner Health Center - Covington
 Greg A Bizette Ph: 985-871-2549
  Monroe
 Louisiana State University Health Sciences Center - Monroe
 Gary V Burton Ph: 318-813-1412
  New Orleans
 CCOP - Ochsner
 Greg A Bizette Ph: 985-871-2549
 Medical Center of Louisiana - New Orleans
 Robert W Veith Ph: 504-568-3410
  Email: aconne1@lsuhsc.edu
 New Orleans Cancer Institute at Memorial Medical Center
 Greg A Bizette Ph: 985-871-2549
 Ochsner Cancer Institute at Ochsner Clinic Foundation
 Greg A Bizette Ph: 985-871-2549
 Stanley S. Scott Cancer Center at Louisiana State University Medical Center - New Orleans
 Robert W Veith Ph: 504-568-3410
  Email: aconne1@lsuhsc.edu
 Tulane Cancer Center at Tulane University Hospital and Clinic
 Hana F Safah Ph: 504-988-6121
  Shreveport
 Feist-Weiller Cancer Center at Louisiana State University Health Sciences
 Gary V Burton Ph: 318-813-1412
 Highland Clinic
 Gary V Burton Ph: 318-813-1412
Maine
  Augusta
 Harold Alfond Center for Cancer Care
 Thomas Henry Openshaw Ph: 207-973-4274
  Bangor
 CancerCare of Maine at Eastern Maine Medical Center
 Thomas Henry Openshaw Ph: 207-973-4274
Maryland
  Baltimore
 Alvin and Lois Lapidus Cancer Institute at Sinai Hospital
 Mukund S. Didolkar Ph: 410-601-6120
  Email: pridgely@lifebridgehealth.org
 Greater Baltimore Medical Center Cancer Center
 Madhu Chaudhry Ph: 443-849-3706
 Mercy Medical Center
 David A. Riseberg Ph: 410-951-7950
  Email: prc@mdmercy.com
  Elkton MD
 Union Hospital of Cecil County
 Stephen Scott Grubbs Ph: 302-733-6227
Massachusetts
  Attleboro
 Sturdy Memorial Hospital
 Colleen K Yavarow Ph: 508-236-7059
  Burlington
 Lahey Clinic Medical Center - Burlington
 Corrine L Zarwan Ph: 781-744-8027
  Gloucester
 Addison Gilbert Hospital
 Angus P. McIntyre Ph: 978-283-4000ext559
  Hyannis
 Davenport-Mugar Cancer Center at Cape Cod Hospital
 Frank G Basile Ph: 508-862-5799
  Pittsfield
 Berkshire Hematology Oncology, PC
 Harvey Zimbler Ph: 413-496-8205
  Email: Gloria.Gero@berkshirehemonc.com
  Plymouth
 Jordan Hospital Club Cancer Center
 James M Koomey Ph: 508-830-2390
  Email: cancerinfo@jordanhospital.org
Michigan
  Adrian
 Hickman Cancer Center at Bixby Medical Center
 Rex B Mowat Ph: 517-265-0116
 Rex B Mowat Ph: 517-265-0116
  Ann Arbor
 CCOP - Michigan Cancer Research Consortium
 Philip J. Stella Ph: 734-712-3456
 Saint Joseph Mercy Cancer Center
 Philip J. Stella Ph: 734-712-3456
 University of Michigan Comprehensive Cancer Center
 Anne F. Schott Ph: 800-865-1125
  Battle Creek
 Battle Creek Health System Cancer Care Center
 Gilbert D Padula Ph: 616-685-5225
  Big Rapids
 Mecosta County Medical Center
 Gilbert D Padula Ph: 616-685-5225
  Dearborn
 Oakwood Cancer Center at Oakwood Hospital and Medical Center
 Philip J. Stella Ph: 734-712-3456
  Detroit
 Van Elslander Cancer Center at St. John Hospital and Medical Center
 Philip J. Stella Ph: 734-712-3456
 Wayne State University
 Lawrence E. Flaherty Ph: 313-576-9363
  Escanaba
 Green Bay Oncology, Limited - Escanaba
 Matthew L Ryan Ph: 800-432-6049
  Flint
 Hurley Medical Center
 Philip J. Stella Ph: 734-712-3456
  Grand Rapids
 Butterworth Hospital at Spectrum Health
 Gilbert D Padula Ph: 616-685-5225
 CCOP - Grand Rapids
 Gilbert D Padula Ph: 616-685-5225
 Lacks Cancer Center at Saint Mary's Health Care
 Gilbert D Padula Ph: 616-685-5225
  Iron Mountain
 Green Bay Oncology - Iron Mountain
 Matthew L Ryan Ph: 800-432-6049
  Jackson
 Gayle M. Jacob Cancer Center at Allegiance Health
 Philip J. Stella Ph: 734-712-3456
  Kalamazoo
 Borgess Medical Center
 Raymond Sterling Lord Ph: 269-373-7458
 Bronson Methodist Hospital
 Raymond Sterling Lord Ph: 269-373-7458
 West Michigan Cancer Center
 Raymond Sterling Lord Ph: 269-373-7458
  Lansing
 Sparrow Regional Cancer Center
 Philip J. Stella Ph: 734-712-3456
  Livonia
 St. Mary Mercy Hospital
 Philip J. Stella Ph: 734-712-3456
  Marquette
 Upper Michigan Cancer Center at Marquette General Hospital
 Amy Weise Ph: 313-576-9363
  Midland
 MidMichigan Medical Center - Midland
 Michel R. Hurtubise Ph: 989-839-3377
  Monroe
 Community Cancer Center of Monroe
 Rex B Mowat Ph: 517-265-0116
 Mercy Memorial Hospital - Monroe
 Rex B Mowat Ph: 517-265-0116
  Mount Clemens
 Clemens Regional Medical Center
 Justin F Klamerus Ph: 800-248-6777
  Muskegon
 Mercy General Health Partners
 Gilbert D Padula Ph: 616-685-5225
  Pontiac
 St. Joseph Mercy Oakland
 Philip J. Stella Ph: 734-712-3456
  Port Huron
 Mercy Regional Cancer Center at Mercy Hospital
 Philip J. Stella Ph: 734-712-3456
  Royal Oak
 William Beaumont Hospital - Royal Oak Campus
 Padmaja V Venuturumilli Ph: 248-551-7695
  Saginaw
 Seton Cancer Institute at Saint Mary's - Saginaw
 Philip J. Stella Ph: 734-712-3456
  Saint Joseph
 Lakeside Cancer Specialists, PLLC
 Robin Zon Ph: 574-234-5123
  Southfield
 Providence Hospital - Southfield
 Anibal Drelichman Ph: 248-849-5337
  Email: jaswinder.grewal@stjohn.org
  St. Joseph
 Lakeland Regional Cancer Care Center - St. Joseph
 Robin Zon Ph: 574-234-5123
  Traverse City
 Munson Medical Center
 Gilbert D Padula Ph: 616-685-5225
  Warren
 St. John Macomb Hospital
 Philip J. Stella Ph: 734-712-3456
Minnesota
  Burnsville
 Fairview Ridges Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Coon Rapids
 Mercy and Unity Cancer Center at Mercy Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Edina
 Fairview Southdale Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Fridley
 Mercy and Unity Cancer Center at Unity Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Hutchinson
 Hutchinson Area Health Care
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Maplewood
 HealthEast Cancer Care at St. John's Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
 Minnesota Oncology - Maplewood
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Minneapolis
 Hennepin County Medical Center - Minneapolis
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
 Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Robbinsdale
 Humphrey Cancer Center at North Memorial Outpatient Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Saint Cloud
 CentraCare Clinic - Women and Children
 Donald J Jurgens Ph: 877-229-4907
  Email: coborncancercenter@centracare.com
 Coborn Cancer Center
 Donald J Jurgens Ph: 877-229-4907
  Email: coborncancercenter@centracare.com
  Saint Louis Park
 CCOP - Metro-Minnesota
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
 Park Nicollet Cancer Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Saint Paul
 Regions Hospital Cancer Care Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
 United Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Shakopee
 St. Francis Cancer Center at St. Francis Medical Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Stillwater
 Lakeview Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Waconia
 Ridgeview Medical Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Willmar
 Willmar Cancer Center at Rice Memorial Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Woodbury
 Minnesota Oncology - Woodbury
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
Mississippi
  Jackson
 University of Mississippi Cancer Clinic
 Barbara S Craft Ph: 601-815-6700
  Pascagoula
 Regional Cancer Center at Singing River Hospital
 James E. Clarkson Ph: 228-809-5292
Missouri
  Cape Girardeau
 Saint Francis Medical Center
 Bethany G. Sleckman Ph: 913-948-5588
 Southeast Cancer Center
 Alan Philip Lyss Ph: 800-392-0936
  Columbia
 Ellis Fischel Cancer Center at University of Missouri - Columbia
 Carl E. Freter Ph: 573-882-7440
  Jefferson City
 Goldschmidt Cancer Center
 Alan Philip Lyss Ph: 800-392-0936
  Joplin
 Freeman Cancer Institute at Freeman Health System
 John H Vu Ph: 417-347-4030
 St. John's Regional Medical Center
 Mark Joseph Skelley Ph: 417-625-2488
  Kansas City
 Truman Medical Center - Hospital Hill
 Peter J. VanVeldhuizen Ph: 800-525-1483
  Saint Louis
 CCOP - St. Louis-Cape Girardeau
 Bethany G. Sleckman Ph: 913-948-5588
 David C. Pratt Cancer Center at St. John's Mercy
 Bethany G. Sleckman Ph: 913-948-5588
 Mercy Clinic St. Louis Cancer and Breast Institute
 Bethany G. Sleckman Ph: 913-948-5588
 Missouri Baptist Cancer Center
 Alan Philip Lyss Ph: 800-392-0936
 Saint Louis University Cancer Center
 Mark J Fesler Ph: 314-977-4440
 Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
 Michael J. Naughton Ph: 800-600-3606
  Email: info@siteman.wustl.edu
  Springfield
 Cancer Research for the Ozarks
 Robert L Carolla Ph: 417-269-4520
 Hulston Cancer Center at Cox Medical Center South
 Robert L Carolla Ph: 417-269-4520
 St. John's Regional Health Center
 Robert L Carolla Ph: 417-269-4520
Montana
  Billings
 Billings Clinic Cancer Center - 801 N 29th Street
 Benjamin Thomas Marchello Ph: 800-648-6274
 CCOP - Montana Cancer Consortium
 Benjamin Thomas Marchello Ph: 800-648-6274
 Hematology-Oncology Centers of the Northern Rockies - Billings
 Benjamin Thomas Marchello Ph: 800-648-6274
 St. Vincent Healthcare Cancer Care Services
 Benjamin Thomas Marchello Ph: 800-648-6274
  Bozeman
 Bozeman Deaconess Cancer Center
 Benjamin Thomas Marchello Ph: 800-648-6274
 Benjamin Thomas Marchello Ph: 800-648-6274
  Butte
 St. James Healthcare Cancer Care
 Benjamin Thomas Marchello Ph: 800-648-6274
  Great Falls
 Benefis Sletten Cancer Institute
 Grant William Harrer Ph: 406-731-8217
  Helena
 St. Peter's Hospital
 Benjamin Thomas Marchello Ph: 800-648-6274
  Kalispell
 Kalispell Regional Medical Center
 Benjamin Thomas Marchello Ph: 800-648-6274
  Missoula
 Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
 Benjamin Thomas Marchello Ph: 800-648-6274
 Montana Cancer Specialists at Montana Cancer Center
 Benjamin Thomas Marchello Ph: 800-648-6274
Nebraska
  Kearney
 Good Samaritan Cancer Center at Good Samaritan Hospital
 Cynthia M. Lewis Ph: 308-865-7963
  Lincoln
 Cancer Resource Center - Lincoln
 Gamini S. Soori Ph: 800-253-4368
  Omaha
 Alegant Health Cancer Center at Bergan Mercy Medical Center
 Gamini S. Soori Ph: 800-253-4368
 CCOP - Missouri Valley Cancer Consortium
 Gamini S. Soori Ph: 800-253-4368
 Creighton University Medical Center
 Gamini S. Soori Ph: 800-253-4368
 Immanuel Medical Center
 Gamini S. Soori Ph: 800-253-4368
 Methodist Estabrook Cancer Center
 Robert M. Langdon Ph: 402-354-5144
Nevada
  Reno
 Renown Institute for Cancer at Renown Regional Medical Center
 Steven A. Schiff Ph: 775-982-4400
New Hampshire
  Dover
 Seacoast Cancer Center at Wentworth - Douglass Hospital
 Barbara Shea Ph: 603-740-2150
  Lebanon
 Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
 Mary D Chamberlin Ph: 800-639-6918
  Email: cancer.research.nurse@dartmouth.edu
  Nashua
 Foundation Medical Partners
 S. G Rao Ph: 603-577-3200
  Email: fmpclinicaltrials@snhmc.org
New Jersey
  Camden
 Cancer Institute of New Jersey at Cooper University Hospital - Camden
 Stephen Scott Grubbs Ph: 302-733-6227
  Englewood
 Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center
 Michael A. Schleider Ph: 201-894-3456
  Morristown
 Carol G. Simon Cancer Center at Morristown Memorial Hospital
 Bonni L Guerin Ph: 908-522-2043
  New Brunswick
 Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
 Deborah L. Toppmeyer Ph: 732-235-8675
 Saint Peter's University Hospital
 Sameer P Desai Ph: 888-823-5923
  Email: ctsucontact@westat.com
  Newark
 Newark Beth Israel Medical Center
 Lori Schleicher Ph: 973-926-7230
  Ridgewood
 Valley Hospital - Ridgewood
 Thomas J. Rakowski Ph: 201-634-5792
  Somerville
 Somerset Medical Center
 Kathleen C Toomey Ph: 908-685-2481
  Sparta
 Frederick R. and Betty M. Smith Cancer Treatment Center
 Allison Zibelli Ph: 215-955-6084
  Summit
 Overlook Hospital
 Bonni L Guerin Ph: 908-522-2043
New Mexico
  Albuquerque
 Lovelace Medical Center - Downtown
 Melanie E. Royce Ph: 505-727-8000
 Presbyterian Cancer Treatment Center at Presbyterian Kaseman Hospital
 Melanie E. Royce Ph: 505-727-8000
 University of New Mexico Cancer Center
 Melanie E. Royce Ph: 505-727-8000
New York
  Buffalo
 Roswell Park Cancer Institute
 Ellis G. Levine Ph: 877-275-7724
  Glens Falls
 Charles R. Wood Cancer Center at Glens Falls Hospital
 Eric A Pillemer Ph: 518-926-6700
  Middletown
 Tucker Center for Cancer Care at Orange Regional Medical Center
 Jeffrey M. Stewart Ph: 845-342-7609
  Mineola
 Winthrop University Hospital
 Nina D'Abreo Ph: 866-946-8476
  New York
 Beth Israel Medical Center - Petrie Division
 Paula Klein Ph: 212-367-1729
 St. Luke's - Roosevelt Hospital Center - St.Luke's Division
 Paula Klein Ph: 212-367-1729
  Poughkeepsie
 Saint Francis Hospital Cancer Center
 Theodora S. Budnik Ph: 845-483-5997
  Email: Cancer@sfhhc.org
  Rochester
 Lipson Cancer and Blood Center at Rochester General Hospital
 Peter Bushunow Ph: 585-922-3536
  Email: tia.derosa@rochestergeneral.org
  Staten Island
 Nalitt Cancer Institute at Staten Island University Hospital
 Qun Dai Ph: 718-226-8888
  Stony Brook
 Stony Brook University Cancer Center
 Andrzej P Kudelka Ph: 800-862-2215
North Carolina
  Asheboro
 Randolph Hospital
 Peter Rubin Ph: 336-832-0821
  Asheville
 Mission Hospitals - Memorial Campus
 Christopher H Chay Ph: 828-213-4150
  Goldsboro
 Wayne Memorial Hospital, Incorporated
 James N. Atkins Ph: 919-580-0000
  Greensboro
 Moses Cone Regional Cancer Center at Wesley Long Community Hospital
 Peter Rubin Ph: 336-832-0821
  Kinston
 Kinston Medical Specialists
 Peter R. Watson Ph: 252-559-2200
  Reidsville
 Annie Penn Cancer Center
 Peter Rubin Ph: 336-832-0821
  Statesville
 Iredell Memorial Hospital
 Ruby A. Grimm Ph: 704-873-5661
  Washington
 Marion L. Shepard Cancer Center at Beaufort County Hospital
 John J Inzerillo Ph: 252-975-4308ext104
  Email: sbell@brhealthsystem.org
  Wilmington
 Zimmer Cancer Center at New Hanover Regional Medical Center
 Cyrus A. Kotwall Ph: 910-342-3000
  Email: cancer.research@nhrmc.org
  Winston-Salem
 Wake Forest University Comprehensive Cancer Center
 Edward A. Levine Ph: 336-713-6771
North Dakota
  Bismarck
 Medcenter One Hospital Cancer Care Center
 Edward J. Wos Ph: 701-323-5760
  Email: tfischer@mohs.org
 Mid Dakota Clinic, PC
 Edward J. Wos Ph: 701-323-5760
  Email: tfischer@mohs.org
 St. Alexius Medical Center Cancer Center
 Edward J. Wos Ph: 701-323-5760
  Email: tfischer@mohs.org
  Grand Forks
 Altru Cancer Center at Altru Hospital
 Grant R Seeger Ph: 701-780-6520
Ohio
  Akron
 McDowell Cancer Center at Akron General Medical Center
 Esther H. Rehmus Ph: 330-344-6348
 Summa Center for Cancer Care at Akron City Hospital
 Jennifer E Payne Ph: 330-375-6101
  Barberton
 Barberton Citizens Hospital
 Jennifer E Payne Ph: 330-375-6101
  Beachwood
 Cleveland Clinic Taussig Cancer Center
 Anjali S Advani Ph: 866-223-8100
  Bowling Green
 Wood County Oncology Center
 Rex B Mowat Ph: 517-265-0116
  Canton
 Aultman Cancer Center at Aultman Hospital
 Kisa E Weeman Ph: 330-363-6891
  Chillicothe
 Adena Regional Medical Center
 J. Philip Kuebler Ph: 614-566-3275
  Cincinnati
 Bethesda North Hospital
 Jose G Barreau Ph: 513-862-2230
 Christ Hospital Cancer Center
 Jennifer B Manders Ph: 513-585-2859
 Good Samaritan Hospital Cancer Treatment Center
 Jose G Barreau Ph: 513-862-2230
  Cleveland
 Case Comprehensive Cancer Center
 Paula Silverman Ph: 800-641-2422
 Cleveland Clinic Cancer Center at Fairview Hospital
 Anjali S Advani Ph: 866-223-8100
 Cleveland Clinic Taussig Cancer Center
 Anjali S Advani Ph: 866-223-8100
 MetroHealth Cancer Care Center at MetroHealth Medical Center
 Bruce J. Averbook Ph: 216-778-8526
  Email: kbauchens@metrohealth.org
  Columbus
 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center
 Maryam B Lustberg Ph: 866-627-7616
  Email: osu@emergingmed.com
 CCOP - Columbus
 J. Philip Kuebler Ph: 614-566-3275
 Doctors Hospital at Ohio Health
 J. Philip Kuebler Ph: 614-566-3275
 Grant Medical Center Cancer Care
 J. Philip Kuebler Ph: 614-566-3275
 Mount Carmel Health - West Hospital
 J. Philip Kuebler Ph: 614-566-3275
 Riverside Methodist Hospital Cancer Care
 J. Philip Kuebler Ph: 614-566-3275
  Dayton
 CCOP - Dayton
 Howard M. Gross Ph: 317-783-8918
 David L. Rike Cancer Center at Miami Valley Hospital
 Howard M. Gross Ph: 317-783-8918
 Good Samaritan Hospital
 Howard M. Gross Ph: 317-783-8918
 Grandview Hospital
 Howard M. Gross Ph: 317-783-8918
 Samaritan North Cancer Care Center
 Howard M. Gross Ph: 317-783-8918
  Delaware
 Grady Memorial Hospital
 J. Philip Kuebler Ph: 614-566-3275
  Elyria
 Hematology Oncology Center
 Rex B Mowat Ph: 517-265-0116
 Mercy Cancer Center - Elyria
 Rex B Mowat Ph: 517-265-0116
  Findlay
 Blanchard Valley Regional Cancer Center
 Howard M. Gross Ph: 317-783-8918
  Franklin
 Atrium Medical Center
 Howard M. Gross Ph: 317-783-8918
  Greenville
 Wayne Hospital
 Howard M. Gross Ph: 317-783-8918
  Independence
 Cleveland Clinic Taussig Cancer Center
 Anjali S Advani Ph: 866-223-8100
  Kettering
 Charles F. Kettering Memorial Hospital
 Howard M. Gross Ph: 317-783-8918
  Lancaster
 Fairfield Medical Center
 J. Philip Kuebler Ph: 614-566-3275
  Lima
 Lima Memorial Hospital
 Rex B Mowat Ph: 517-265-0116
 St. Rita's Medical Center
 Henry Gerad Ph: 419-226-9617
  Mansfield
 MedCentral - Mansfield Hospital
 Robert E Exten Ph: 419-526-8018
  Marietta
 Strecker Cancer Center at Marietta Memorial Hospital
 J. Philip Kuebler Ph: 614-566-3275
  Maumee
 Northwest Ohio Oncology Center
 Rex B Mowat Ph: 517-265-0116
 Rex B Mowat Ph: 517-265-0116
  Mayfield Heights
 Hillcrest Cancer Center at Hillcrest Hospital
 Anjali S Advani Ph: 866-223-8100
  Mount Vernon
 Knox Community Hospital
 J. Philip Kuebler Ph: 614-566-3275
  Newark
 Licking Memorial Cancer Care Program at Licking Memorial Hospital
 J. Philip Kuebler Ph: 614-566-3275
  Oregon
 St. Charles Mercy Hospital
 Rex B Mowat Ph: 517-265-0116
 Toledo Clinic - Oregon
 Rex B Mowat Ph: 517-265-0116
  Parma
 Parma Community General Hospital
 Anjali S Advani Ph: 866-223-8100
  Sandusky
 North Coast Cancer Care, Incorporated
 Anjali S Advani Ph: 866-223-8100
  Springfield
 Community Hospital of Springfield and Clark County
 J. Philip Kuebler Ph: 614-566-3275
  Strongsville
 Cleveland Clinic Foundation - Strongsville
 Anjali S Advani Ph: 866-223-8100
  Sylvania
 Flower Hospital Cancer Center
 Rex B Mowat Ph: 517-265-0116
  Tiffin
 Mercy Hospital of Tiffin
 Rex B Mowat Ph: 517-265-0116
  Toledo
 CCOP - Toledo Community Hospital
 Rex B Mowat Ph: 517-265-0116
 St. Anne Mercy Hospital
 Rex B Mowat Ph: 517-265-0116
 St. Vincent Mercy Medical Center
 Rex B Mowat Ph: 517-265-0116
 Toledo Clinic, Incorporated - Main Clinic
 Rex B Mowat Ph: 517-265-0116
 Toledo Hospital
 Rex B Mowat Ph: 517-265-0116
 University of Toledo Medical Center
 Rex B Mowat Ph: 517-265-0116
  Troy
 UVMC Cancer Care Center at Upper Valley Medical Center
 Howard M. Gross Ph: 317-783-8918
  Wauseon
 Fulton County Health Center
 Rex B Mowat Ph: 517-265-0116
  Westerville
 Mount Carmel St. Ann's Cancer Center
 J. Philip Kuebler Ph: 614-566-3275
  Wooster
 Cleveland Clinic - Wooster
 Anjali S Advani Ph: 866-223-8100
  Xenia
 Ruth G. McMillan Cancer Center at Greene Memorial Hospital
 Howard M. Gross Ph: 317-783-8918
  Zanesville
 Genesis - Good Samaritan Hospital
 J. Philip Kuebler Ph: 614-566-3275
Oklahoma
  Norman
 Cancer Care Associates - Norman
 Vikki Ann Canfield Ph: 888-823-5923
  Email: ctsucontact@westat.com
  Oklahoma City
 Cancer Care Associates - Mercy Campus
 Vikki Ann Canfield Ph: 888-823-5923
  Email: ctsucontact@westat.com
 Oklahoma University Cancer Institute
 George B Selby Ph: 405-271-4272
  Email: julie-traylor@ouhsc.edu
  Tulsa
 Natalie Warren Bryant Cancer Center at St. Francis Hospital
 Joseph P. Lynch Ph: 918-494-2200
Oregon
  Bend
 St. Charles Medical Center - Bend
 Robert Boone Ph: 541-706-2659
  Clackamas
 Clackamas Radiation Oncology Center
 Alison K Conlin Ph: 503-215-6412
  Grants Pass
 Three Rivers Community Hospital
 Charles R. Dibb Ph: 541-789-6176
  Medford
 Dubs Cancer Center at Rogue Valley Medical Center
 Charles R. Dibb Ph: 541-789-6176
 Providence Cancer Center at PMCC
 Charles R. Dibb Ph: 541-789-6176
  Milwaukie
 Providence Milwaukie Hospital
 Alison K Conlin Ph: 503-215-6412
  Newberg
 Providence Newberg Medical Center
 Alison K Conlin Ph: 503-215-6412
  Oregon City
 Willamette Falls Hospital
 Alison K Conlin Ph: 503-215-6412
  Portland
 CCOP - Columbia River Oncology Program
 Alison K Conlin Ph: 503-215-6412
 Kaiser Permanente Health Care - Portland
 Nagendra Tirumali Ph: 503-335-2400
 Providence Cancer Center at Providence Portland Medical Center
 Alison K Conlin Ph: 503-215-6412
 Providence St. Vincent Medical Center
 Alison K Conlin Ph: 503-215-6412
Pennsylvania
  Abington
 Rosenfeld Cancer Center at Abington Memorial Hospital
 Willard G. Andrews Ph: 215-481-2402
  Danville
 Geisinger Cancer Institute at Geisinger Health
 Victor Gerald Vogel Ph: 570-271-5251
  Doylestown
 Doylestown Hospital Cancer Center
 Mitchell Alden Ph: 215-345-2378
  Email: lheacock@dh.org
  Easton
 Easton Regional Cancer Center at Easton Hospital
 Rajen P Oza Ph: 610-250-4000
  Gettysburg
 Adams Cancer Center
 Amir Tabatabai Ph: 877-441-7957
  Hanover
 Cherry Tree Cancer Center
 Amir Tabatabai Ph: 877-441-7957
  Hazleton
 Geisinger Hazleton Cancer Center
 Victor Gerald Vogel Ph: 570-271-5251
  Media
 Riddle Memorial Hospital Cancer Center
 Allison Zibelli Ph: 215-955-6084
  Philadelphia
 Fox Chase Cancer Center - Philadelphia
 Lori J. Goldstein Ph: 215-728-4790
 Joan Karnell Cancer Center at Pennsylvania Hospital
 Lee Hartner Ph: 800-789-7366
  Pottstown
 Pottstown Memorial Regional Cancer Center
 Wei Song Ph: 610-327-7544
  Sayre
 Guthrie Cancer Center at Guthrie Clinic Sayre
 Edward T. O'Brien Ph: 800-836-0388
  Scranton
 Hematology and Oncology Associates of North East Pennsylvania
 Allison Zibelli Ph: 215-955-6084
 Mercy Hospital Cancer Center - Scranton
 Martin B. Hyzinski Ph: 570-558-3020
 Scranton Hematology Oncology
 Martin B. Hyzinski Ph: 570-558-3020
  State College
 Geisinger Medical Group - Scenery Park
 Victor Gerald Vogel Ph: 570-271-5251
  Upland
 Associates in Hematology-Oncology, PC at Crozer Regional Cancer Center
 Allison Zibelli Ph: 215-955-6084
  West Reading
 McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center
 Terrence P. Cescon Ph: 610-988-9323
  Wilkes-Barre
 Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
 Victor Gerald Vogel Ph: 570-271-5251
  Williamsport
 Susquehanna Cancer Center at Divine Providence Hospital
 Warren L Robinson Ph: 800-598-4282
  York
 WellSpan Health
 Amir Tabatabai Ph: 877-441-7957
PR
  San Juan
 San Juan City Hospital
 Luis Baez-Diaz Ph: 787-767-3733
Rhode Island
  Providence
 Women and Infants Hospital of Rhode Island
 Bachir J Sakr Ph: 401-274-1122
South Carolina
  Anderson
 AnMed Cancer Center
 James Dewitt Bearden Ph: 800-486-5941
  Charleston
 Hollings Cancer Center at Medical University of South Carolina
 Rita M Kramer Ph: 843-792-9321
  Florence
 McLeod Regional Medical Center
 Rajesh Bajaj Ph: 843-679-7256
  Greenville
 Cancer Centers of the Carolinas - Faris Road
 Jeffrey Kent Giguere Ph: 864-241-6251
 Cancer Centers of the Carolinas - Grove Commons
 Jeffrey Kent Giguere Ph: 864-241-6251
 CCOP - Greenville
 Jeffrey Kent Giguere Ph: 864-241-6251
 Greenville Memorial Hospital
 Jeffrey Kent Giguere Ph: 864-241-6251
  Greenwood
 Self Regional Cancer Center at Self Regional Medical Center
 Joanna K Metzner-Sadurski Ph: 864-725-4771
  Greer
 Cancer Centers of the Carolinas - Greer Medical Oncology
 Jeffrey Kent Giguere Ph: 864-241-6251
  Seneca
 Cancer Centers of the Carolinas - Seneca
 Jeffrey Kent Giguere Ph: 864-241-6251
  Spartanburg
 Cancer Centers of the Carolinas - Spartanburg
 Jeffrey Kent Giguere Ph: 864-241-6251
 CCOP - Upstate Carolina
 James Dewitt Bearden Ph: 800-486-5941
 Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
 James Dewitt Bearden Ph: 800-486-5941
  West Columbia
 Lexington Medical Center
 Steven A Madden Ph: 803-936-8050
South Dakota
  Aberdeen
 Conklin Regional Cancer Center
 Richard J. Conklin Ph: 605-622-5613
  Rapid City
 Rapid City Regional Hospital
 Mark T Schroeder Ph: 605-716-3982
  Email: research@rcrh.org
  Sioux Falls
 Avera Cancer Institute
 Addison R Tolentino Ph: 800-657-4377
  Email: Jan.Healy@avera.org
Tennessee
  Chattanooga
 Erlanger Cancer Center at Erlanger Hospital - Baroness
 Larry L. Schlabach Ph: 423-778-6947
  Cookeville
 Cookeville Regional Medical Center
 Paul N Jacquin Ph: 931-783-2714
  Kingsport
 Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center
 Asheesh Shipstone Ph: 423-578-8538
  Knoxville
 Thompson Cancer Survival Center
 Samuel Spence McCachren Ph: 865-541-1812
 U.T. Medical Center Cancer Institute
 Timothy John Panella Ph: 865-544-9773
  Nashville
 MBCCOP - Meharry Medical College - Nashville
 Steven N. Wolff Ph: 615-327-5724
  Email: jmurray@mmc.edu
 Nashville Breast Center
 Steven N. Wolff Ph: 615-327-5724
  Email: jmurray@mmc.edu
Texas
  Amarillo
 Harrington Cancer Center
 Brian T. Pruitt Ph: 806-359-4673
  Email: ryokubaitis@harringtoncc.org
  Fort Worth
 All Saints Episcopal Hospital - Fort Worth
 Sanjay P Oommen Ph: 800-422-9567
  Galveston
 University of Texas Medical Branch
 Mary J Ninan Ph: 409-772-1950
  Email: clinical.research@utmb.edu
  Houston
 Dan L. Duncan Cancer Center at Baylor College of Medicine
 Mothaffar F Rimawi Ph: 713-798-1354
  Email: burton@bcm.edu
 Univeristy of Texas M.D. Anderson Cancer Center
 Ana Maria Gonzalez-Angulo Ph: 713-792-3245
  Irving
 Baylor Medical Center at Irving
 Naveena Allada Ph: 800-422-9567
  Laredo
 Doctor's Hospital of Laredo
 Gary W. Unzeitig Ph: 888-823-5923
  Email: ctsucontact@westat.com
  Lubbock
 Texas Tech University Health Sciences Center
 Candy Arentz Ph: 806-775-8590
  San Antonio
 Cancer Therapy and Research Center
 Peter M Ravdin Ph: 210-616-5798
 University Hospital - San Antonio
 Peter M Ravdin Ph: 210-616-5798
 University of Texas Health Science Center at San Antonio
 Peter M Ravdin Ph: 210-616-5798
 Veterans Affairs Medical Center - San Antonio (Murphy)
 Peter M Ravdin Ph: 210-616-5798
Utah
  Salt Lake City
 Huntsman Cancer Institute at University of Utah
 Saundra S. Buys Ph: 801-581-4477
  Email: clinical.trials@hci.utah.edu
Virginia
  Charlottesville
 University of Virginia Cancer Center
 Patrick M Dillon Ph: 434-243-6143
  Danville
 Danville Regional Medical Center
 Timothy W. Brotherton Ph: 434-793-0044
  Fredericksburg
 Fredericksburg Oncology Inc
 Rex B Mowat Ph: 517-265-0116
  Lynchburg
 Lynchburg Hematology-Oncology Clinic
 John Leach MacNeill Ph: 434-200-5925
  Norton
 Southwest Virginia Regional Cancer Center at Wellmonth Health
 Asheesh Shipstone Ph: 423-578-8538
Washington
  Bellingham
 St. Joseph Cancer Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Bremerton
 Olympic Hematology and Oncology
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Centralia
 Providence Centralia Hospital
 Yoshio Inoue Ph: 253-403-2394
  Federal Way
 St. Francis Hospital
 Yoshio Inoue Ph: 253-403-2394
  Kennewick
 Columbia Basin Hematology
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Kirkland
 Cascade Cancer Center at Evergreen Hospital Medical Center
 Craig R. Nichols Ph: 503-215-6412
  Mount Vernon
 Skagit Valley Hospital Cancer Care Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Olympia
 Providence St. Peter Hospital Regional Cancer Center
 Yoshio Inoue Ph: 253-403-2394
  Poulsbo
 Harrison Poulsbo Hematology and Onocology
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Puyallup
 Good Samaritan Cancer Center
 Yoshio Inoue Ph: 253-403-2394
  Seattle
 CCOP - Virginia Mason Research Center
 Craig R. Nichols Ph: 503-215-6412
 Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Group Health Central Hospital
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Harborview Medical Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Minor and James Medical, PLLC
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Pacific Medical Center
 Craig R. Nichols Ph: 503-215-6412
 Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 University Cancer Center at University of Washington Medical Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Virginia Mason Medical Center
 Craig R. Nichols Ph: 503-215-6412
  Spokane
 Cancer Care Northwest - Spokane South
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Evergreen Hematology and Oncology, PS
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Tacoma
 Allenmore Hospital
 Yoshio Inoue Ph: 253-403-2394
 CCOP - Northwest
 Yoshio Inoue Ph: 253-403-2394
 Franciscan Cancer Center at St. Joseph Medical Center
 Yoshio Inoue Ph: 253-403-2394
 MultiCare Regional Cancer Center at Tacoma General Hospital
 Yoshio Inoue Ph: 253-403-2394
 St. Clare Hospital
 Yoshio Inoue Ph: 253-403-2394
  Vancouver
 Northwest Cancer Specialists at Vancouver Cancer Center
 Alison K Conlin Ph: 503-215-6412
 Southwest Washington Medical Center Cancer Center
 Alison K Conlin Ph: 503-215-6412
  Walla Walla
 St. Mary Regional Cancer Center at St. Mary Medical Center
 James R Cunningham Ph: 800-422-6237
  Wenatchee
 Wenatchee Valley Medical Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
West Virginia
  Huntington
 Edwards Comprehensive Cancer Center at Cabell Huntington Hospital
 Maria-Rosalia B. Tria Tirona Ph: 304-399-6617
  Parkersburg
 Community Comprehensive Cancer Center at Camden-Clark Memorial Hospital
 Nik M. Shah Ph: 304-424-2585
Wisconsin
  Antigo
 Langlade Memorial Hospital
 Christopher G Peterson Ph: 877-405-6866
  Appleton
 Fox Valley Hematology and Oncology - East Grant Street
 Avi Bar-Lev Ph: 920-749-1171
  Chippewa Falls
 Marshfield Clinic - Chippewa Center
 Matthias Weiss Ph: 800-347-0673
  Eau Claire
 Marshfield Clinic Cancer Care at Regional Cancer Center
 Matthias Weiss Ph: 800-347-0673
  Green Bay
 Green Bay Oncology, Limited at St. Mary's Hospital
 Matthew L Ryan Ph: 800-432-6049
 Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
 Matthew L Ryan Ph: 800-432-6049
 St. Mary's Hospital Medical Center - Green Bay
 Matthew L Ryan Ph: 800-432-6049
 St. Vincent Hospital Regional Cancer Center
 Matthew L Ryan Ph: 800-432-6049
  Janesville
 Mercy Regional Cancer Center
 Robert Delaune Ph: 800-928-1103
  Johnson Creek
 UW Cancer Center Johnson Creek
 Kari B Wisinski Ph: 877-405-6866
  La Crosse
 Franciscan Skemp Healthcare - La Crosse Campus
 Paula Gill Ph: 608-392-9462
 Gundersen Lutheran Center for Cancer and Blood
 Kurt Oettel Ph: 608-775-2385
  Email: cancerctr@gundluth.org
  Madison
 University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
 Kari B Wisinski Ph: 877-405-6866
  Manitowoc
 Holy Family Memorial Medical Center Cancer Care Center
 Matthew L Ryan Ph: 800-432-6049
  Marinette
 Bay Area Cancer Care Center at Bay Area Medical Center
 Matthew L Ryan Ph: 800-432-6049
  Marshfield
 Marshfield Clinic - Marshfield Center
 Matthias Weiss Ph: 800-347-0673
  Milwaukee
 Columbia-Saint Mary's Cancer Care Center
 Varsha V Shah Ph: 414-326-2675
  Email: clinicaltrials@columbia-stmarys.org
  Minocqua
 Marshfield Clinic - Lakeland Center
 Matthias Weiss Ph: 800-347-0673
  Mukwonago
 D.N. Greenwald Center
 Michael A Thompson Ph: 262-928-7632
  New Richmond
 Cancer Center of Western Wisconsin
 Joseph W Leach Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Oconomowoc
 Regional Cancer Center at Oconomowoc Memorial Hospital
 Michael A Thompson Ph: 262-928-7632
  Oconto Falls
 Green Bay Oncology, Limited - Oconto Falls
 Matthew L Ryan Ph: 800-432-6049
  Racine
 All Saints Cancer Center at Wheaton Franciscan Healthcare
 Young M Choi Ph: 414-874-4541
  Email: Kelli.holton@wfhc.org
  Rhinelander
 Ministry Medical Group at Saint Mary's Hospital
 Matthias Weiss Ph: 800-347-0673
  Rice Lake
 Marshfield Clinic - Indianhead Center
 Matthias Weiss Ph: 800-347-0673
  Sheboygan
 Saint Nicholas Hospital
 Matthew L Ryan Ph: 800-432-6049
  Stevens Point
 Marshfield Clinic at Saint Michael's Hospital
 Matthias Weiss Ph: 800-347-0673
  Sturgeon Bay
 Green Bay Oncology, Limited - Sturgeon Bay
 Matthew L Ryan Ph: 800-432-6049
  Waukesha
 Waukesha Memorial Hospital Regional Cancer Center
 Michael A Thompson Ph: 262-928-7632
  Wausau
 Marshfield Clinic - Wausau Center
 Matthias Weiss Ph: 800-347-0673
 University of Wisconcin Cancer Center at Aspirus Wausau Hospital
 Christopher G Peterson Ph: 877-405-6866
  Weston
 Marshfield Clinic - Weston Center
 Matthias Weiss Ph: 800-347-0673
  Wisconsin Rapids
 Marshfield Clinic - Wisconsin Rapids Center
 Matthias Weiss Ph: 800-347-0673
 Riverview UW Cancer Center at Riverview Hospital
 Ron James Kirschling Ph: 877-405-6866
Wyoming
  Casper
 Rocky Mountain Oncology
 Benjamin Thomas Marchello Ph: 800-648-6274
  Sheridan
 Welch Cancer Center at Sheridan Memorial Hospital
 Benjamin Thomas Marchello Ph: 800-648-6274
Spain
  Barcelona
 Hospital de la Santa Cruz i Sant Pau
 Agustin Barnadas Molins
  Email: geicam@geicam.org
  Girona
 Hospital Universitari Josep Trueta de Girona
 Joan Dorca Ribugent Ph: (92) 294-02-00
  Toledo
 Hospital Virgen de la Salud
 Jose Ignacio Chacon Lopez-Muniz
  Email: geicam@geicam.org
  Valencia
 Hospital Clinico Universitario de Valencia
 Ana Lluch Hernandez
  Email: geicam@geicam.org
Guipuzcoa
  San Sebastian
 Onkologikoa
 Arrate Plazaola Alcibar
  Email: geicam@geicam.org

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01272037
Information obtained from ClinicalTrials.gov on April 01, 2013

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.

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