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S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer

Basic Trial Information
Trial Description
     Summary
     Further Trial Information
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIIBiomarker/Laboratory analysis, TreatmentActive18 and overNCI, OtherS1207
U10CA032102, NCI-2012-01995, SWOG-S1207, NCT01674140

Trial Description

Summary

RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using tamoxifen citrate, goserelin acetate, leuprolide acetate, anastrozole, letrozole, or exemestane, may fight breast cancer by lowering the amount of estrogen the body makes. Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet know whether hormone therapy is more effective when given with or without everolimus in treating breast cancer.

PURPOSE: This randomized phase III trial studies how well giving hormone therapy together with or without everolimus work in treating patients with breast cancer.

Further Study Information

OBJECTIVES:

Primary

  • To compare whether the addition of one year of everolimus (10 mg daily) to standard adjuvant endocrine therapy improves invasive disease-free survival (IDFS) in patients with high-risk, hormone-receptor (HR)-positive, and human epidermal growth factor receptor (HER)2-negative breast cancer.

Secondary

  • To compare whether the addition of one year of everolimus to standard adjuvant endocrine therapy improves overall survival (OS) and distant recurrence-free survival (DRFS) in this patient population.
  • To evaluate the safety, toxicities, and tolerability of one year of everolimus in combination with standard adjuvant endocrine therapy and to compare it with standard adjuvant endocrine therapy plus placebo in this patient population.
  • To determine whether the benefit of one year of everolimus use in addition to standard adjuvant endocrine therapy varies by recurrence score (RS), nodal status, or other commonly used prognostic factors.
  • To evaluate adherence to 1-year treatment of everolimus in comparison to placebo in addition to standard adjuvant endocrine therapy in this patient population.
  • To collect specimens in order to evaluate biomarkers of therapeutic efficacy. (exploratory)

OUTLINE: This is a multicenter study. Patients are stratified according to risk level (node-negative and recurrence score [RS] > 25 in the primary tumor, and a tumor measuring ≥ 2 cm in greatest diameter treated with adjuvant therapy vs 1-3 positive lymph nodes and RS > 25 treated with adjuvant therapy vs ≥ 4 positive lymph nodes [any RS value] treated with adjuvant therapy vs ≥ 4 positive lymph nodes [any RS value] prior to or after neoadjuvant chemotherapy). Patients are randomized to 1 of 2 treatment arms.

  • Arm I: Patients receive an approved endocrine therapy comprising tamoxifen citrate*, goserelin acetate** or leuprolide acetate**, or aromatase inhibitor (anastrozole, letrozole, or exemestane) for 2-5 years. Patients also receive a placebo orally (PO) daily for 1 year in the absence of disease progression or unacceptable toxicity.
  • Arm II: Patients receive an approved endocrine therapy regimen as in arm I. Patients also receive everolimus PO daily for 1 year in the absence of disease progression or unacceptable toxicity.

NOTE: *Men receive tamoxifen citrate PO for 5 years.

NOTE: **Goserelin acetate or leuprolide acetate is given if patient is or becomes postmenopausal.

Blood and tissue samples are collected for biomarker studies.

After completion of study treatment, patients are followed up every 6 months for 2 years and then yearly thereafter for 10 years.

Eligibility Criteria

DISEASE CHARACTERISTICS:

  • Patients must have a histologically confirmed diagnosis of invasive breast carcinoma with positive estrogen (ER)- and/or progesterone-receptor (PR) status, and negative human epidermal growth factor receptor (HER)2, for whom standard adjuvant endocrine therapy is planned
  • ER and PR positivity must be assessed according to American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guidelines as either ER or PR ≥ 1% positive nuclear staining
  • HER2 will be determined by immunohistochemistry (IHC) or non-amplified fluorescent in situ hybridization (FISH) or chromogenic in situ hybridization (CISH)
  • If HER2 IHC is 2+, FISH/CISH must be performed and must not be positive (must be a ratio of ≤ 2), but otherwise FISH/CISH is not required if IHC is 0 or 1+ by institutional standards
  • Patients must not have inflammatory breast cancer and must not have metastatic breast cancer (stage IV disease); patients with multifocal, multicentric, and synchronous bilateral breast cancers are allowed
  • Multifocal disease is defined as more than one invasive cancer < 2 cm from the largest lesion within the same breast quadrant
  • Multicentric disease is defined as more than one invasive cancer ≥ 2 cm from the largest lesion within the same breast quadrant or more than one lesion in different quadrants
  • Synchronous bilateral disease is defined as invasive breast cancer in both breasts, diagnosed within 30 days of each other
  • Patients must be high risk by belonging to one of the following risk groups:
  • Completion of adjuvant chemotherapy and pathologically negative axillary nodes, and a tumor measuring ≥ 2 cm in greatest diameter, and an Oncotype DX® recurrence score (RS) > 25 (completed as standard of care)
  • Completion of adjuvant chemotherapy, and pathologically 1-3 positive axillary lymph nodes, and an Oncotype DX® RS > 25 (screened via S1007 or otherwise)
  • Completion of adjuvant chemotherapy and pathologically 4 or more positive axillary lymph nodes independent of the Oncotype DX® RS in the primary tumor
  • Completion of neoadjuvant chemotherapy and 4 or more positive nodes pathologically determined prior to or after chemotherapy
  • Patients must have completed either breast-conserving surgery or total mastectomy, with negative margins and appropriate axillary staging; a negative margin is defined as no evidence of tumor or ductal carcinoma in situ (DCIS) at the line of resection; additional operative procedures may be performed to obtain clear margins
  • Patients who had breast-conserving surgery must have completed whole-breast radiation; use of regional nodal-basin radiation will be at the discretion of the investigator according to institutional guidelines
  • Patients with ≥ 4 positive lymph nodes must have completed breast/chest wall and nodal-basin radiation therapy according to standard-of-care guidelines before randomization; omission of radiation therapy is not allowed in this high-risk population of patients
  • Patients must be registered no sooner than 21 days after completion of radiation therapy and must have recovered (≤ grade 1) from any of the effects of radiation
  • Patients must have undergone axillary staging by sentinel-node biopsy or axillary lymph node dissection (ALND)
  • For patients with 1-3 positive lymph nodes, sentinel-node biopsy alone is allowed provided that the patient completed either whole-breast or chest-wall radiation and the primary tumor is < 2 cm
  • All patients with ≥ 4 positive lymph nodes must have completed ALND (with or without prior sentinel-node biopsy)

PATIENT CHARACTERISTICS:

  • Peripheral granulocyte count ≥ 1,500/mL
  • Hemoglobin ≥ 9 g/dL
  • Platelet count ≥ 100,000/mL
  • Bilirubin ≤ 1.5 mg/dL (≤ 3.0 mg/dL if due to Gilbert syndrome)
  • Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 1.5 times institutional upper limit of normal (IULN)
  • Alkaline phosphatase ≤ 1.5 times IULN
  • Serum creatinine level ≤ IULN
  • Fasting cholesterol ≤ 300 mg/dL and triglycerides ≤ 2.5 times IULN; patients may be on lipid-lowering agents to reach these values
  • Patients must have a performance status of 0-2 by Zubrod criteria
  • Patients must not have any grade III/IV cardiac disease as defined by the New York Heart Association Criteria (i.e., patients with cardiac disease resulting in marked limitation of physical activity or resulting in inability to carry on any physical activity without discomfort), unstable angina pectoris, myocardial infarction within 6 months, or serious uncontrolled cardiac arrhythmia
  • Patients must not have uncontrolled diabetes (defined as a hemoglobin [Hg] A1C > 7% within 28 days prior to registration)
  • Patients known to be human immunodeficiency virus (HIV) positive may be enrolled if baseline CD4 count is > 500 cells/mm³ and they are not taking anti-retroviral therapy
  • Patients with known hepatitis are not eligible
  • Patients must not have any known uncontrolled, underlying pulmonary disease
  • Patients must be able to take oral medications
  • Patients may not have any impairment of gastrointestinal function or gastrointestinal disease that may significantly alter the absorption of blinded drug (e.g., ulcerative disease, uncontrolled nausea, vomiting, diarrhea, malabsorption syndrome, or small bowel resection)
  • Patients must not be pregnant or nursing
  • Women/men of reproductive potential must have agreed to use an effective non-hormonal contraceptive method during and for 8 weeks after completion of study therapy
  • In addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy, or bilateral tubal ligation; corresponding procedures for men include castration, vasectomy, and barrier-contractive devices
  • If at any point a previously celibate patient chooses to become heterosexually active during the protocol therapy, he/she is responsible for beginning contraceptive measures
  • No other prior malignancy is allowed except for adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, or other cancer for which the patient has been disease-free for 5 years

PRIOR CONCURRENT THERAPY:

  • See Disease Characteristics
  • Patients must have completed standard neoadjuvant or adjuvant chemotherapy prior to randomization; completion of chemotherapy will be determined by the treating oncologist, but should include a minimum of 4 courses (a course of weekly paclitaxel is considered 3 doses); patients must be registered within 21 weeks after completion of chemotherapy; patients may have started endocrine therapy at any time after the diagnosis of the current breast cancer
  • Patients must not be receiving or planning to receive trastuzumab
  • Concurrent bisphosphonate therapy is allowed
  • Patients must not have prior exposure to mTOR inhibitors (rapamycin, everolimus, temsirolimus, deforolimus)
  • Patients must not have prior treatment with any investigational drug within the preceding 28 days and must not be planning to receive any other investigational drug for the duration of the study
  • Patients must not be planning to receive any other anticancer drug for the duration of the study
  • Patients must not have an organ allograft or other history of immune compromise; patients must not be receiving chronic, systemic treatment with corticosteroids or other immunosuppressive agent; topical or inhaled corticosteroids are allowed
  • Patients must not have received immunization with an attenuated live vaccine (e.g., intranasal influenza, measles, mumps, and rubella [MMR], oral polio, varicella, zoster, yellow fever, and Bacillus Calmette-Guérin [BCG] vaccines) within seven days prior to registration nor have plans to receive such vaccination while on protocol treatment
  • Patients must not have taken within 14 days prior to registration, be taking, nor plan to take while on protocol treatment, strong cytochrome P450 3A4 (CYP3A4) inhibitors and/or CYP3A4 inducers

Trial Contact Information

Trial Lead Organizations/Sponsors

Southwest Oncology Group

National Cancer Institute

Mariana Chavez-MacGregorPrincipal Investigator

Megan HardinPh: 2106148808 Ext.1014
  Email: mhardin@swog.org

Trial Sites

U.S.A.
Arizona
  Tucson
 Arizona Cancer Center at UMC Orange Grove
 Pavani Chalasani Ph: 520-626-9008
 Arizona Cancer Center at University Medical Center North
 Pavani Chalasani Ph: 520-626-9008
 Arizona Cancer Center at University of Arizona Health Sciences Center
 Pavani Chalasani Ph: 520-626-9008
Arkansas
  Jonesboro
 NEA Medical Clinic - East Matthews
 Carroll Dean Scroggin Ph: 210-614-8808
  Email: protocols@swog.org
California
  Anaheim
 Kaiser Permanente Medical Center - Anaheim/Orange County
 Han A Koh Ph: 626-564-3455
  Antioch
 Kaiser Permanente - Deer Valley
 Louis Fehrenbacher Ph: 626-564-3455
  Baldwin Park
 Kaiser Permanente Medical Center - Baldwin Park
 Han A Koh Ph: 626-564-3455
  Bellflower
 Kaiser Permanente Medical Center - Bellflower
 Han A Koh Ph: 626-564-3455
  Berkeley
 Alta Bates Summit Comprehensive Cancer Center
 Ari D Baron Ph: 650-696-4487
  Email: PazE@sutterhealth.org
  Burlingame
 Peninsula Medical Center
 Ari D Baron Ph: 650-696-4487
  Email: PazE@sutterhealth.org
  Castro Valley
 East Bay Radiation Oncology Center
 James H. Feusner Ph: 510-450-7600
 Valley Medical Oncology Consultants - Castro Valley
 James H. Feusner Ph: 510-450-7600
  Concord
 Cancer Care Center at John Muir Health - Concord Campus
 Deborah L. Kerlin Ph: 925-674-2580
  Duarte
 City of Hope Comprehensive Cancer Center
 Joanne E. Mortimer Ph: 800-826-4673
  Email: becomingapatient@coh.org
  Fairfield
 North Bay Cancer Center
 Brian G Vikstrom Ph: 707-646-4016
  Fontana
 Kaiser Permanente Medical Center - Fontana
 Han A Koh Ph: 626-564-3455
  Fremont
 Kaiser Permanente - Fremont
 Louis Fehrenbacher Ph: 626-564-3455
 Valley Medical Oncology
 James H. Feusner Ph: 510-450-7600
  Fresno
 Kaiser Permanente Fresno Medical Center
 Louis Fehrenbacher Ph: 626-564-3455
  Harbor City
 Kaiser Permanente Medical Center - Harbor City
 Han A Koh Ph: 626-564-3455
  Hayward
 Kaiser Permanente Medical Center - Hayward
 Louis Fehrenbacher Ph: 626-564-3455
  Irvine
 Kaiser Permanente - Irvine
 Han A Koh Ph: 626-564-3455
  LA Jolla
 Rebecca and John Moores UCSD Cancer Center
 Barbara A Parker Ph: 858-822-5354
  Email: cancercto@ucsd.edu
  Loma Linda
 Loma Linda University Cancer Institute at Loma Linda University Medical Center
 Gayathri Nagaraj Ph: 909-558-3375
  Los Angeles
 Kaiser Foundation Hospital - West Los Angeles
 Han A Koh Ph: 626-564-3455
 Kaiser Permanente Medical Center - Los Angeles
 Han A Koh Ph: 626-564-3455
 Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center
 M. W Audeh Ph: 310-423-8965
 USC/Norris Comprehensive Cancer Center and Hospital
 Agustin Garcia Ph: 323-865-0451
 Agustin Garcia Ph: 323-865-0451
  Martinez
 Contra Costa Regional Medical Center
 James H. Feusner Ph: 510-450-7600
  Marysville
 Fremont-Rideout Cancer Center
 Helen K. Chew Ph: 916-734-3089
  Merced
 Mercy Cancer Center at Mercy Medical Center
 Prasad Pillai Ph: 916-734-3089
  Modesto
 Kaiser Permanente-Modesto
 Louis Fehrenbacher Ph: 626-564-3455
  Monterey
 Community Hospital of the Monterey Peninsula Comprehensive Cancer Center
 John Hausdorff Ph: 831-625-4753
  Mountain View
 El Camino Hospital Cancer Center
 James H. Feusner Ph: 510-450-7600
  Novato
 Sutter Health Western Division Cancer Research Group
 Ari D Baron Ph: 650-696-4487
  Email: PazE@sutterhealth.org
  Oakland
 Alta Bates Summit Medical Center - Summit Campus
 James H. Feusner Ph: 510-450-7600
 Bay Area Breast Surgeons, Incorporated
 James H. Feusner Ph: 510-450-7600
 CCOP - Bay Area Tumor Institute
 James H. Feusner Ph: 510-450-7600
 Epic Care - Oakland
 James H. Feusner Ph: 510-450-7600
 Highland General Hospital
 James H. Feusner Ph: 510-450-7600
 Kaiser Permanente-Oakland
 Louis Fehrenbacher Ph: 626-564-3455
 Larry G Strieff MD Medical Corporation
 James H. Feusner Ph: 510-450-7600
 Tom K Lee, Incorporated
 James H. Feusner Ph: 510-450-7600
  Orange
 St. Joseph Hospital Regional Cancer Center - Orange
 David A Margileth Ph: 714-734-6220
  Panorama City
 Kaiser Permanente Medical Group
 Han A Koh Ph: 626-564-3455
  Pleasanton
 Valley Medical Oncology Consultants - Pleasanton
 James H. Feusner Ph: 510-450-7600
  Redwood City
 Kaiser Permanente Medical Center - Redwood City
 Louis Fehrenbacher Ph: 626-564-3455
  Richmond
 Kaiser Permanente Medical Center - Richmond
 Louis Fehrenbacher Ph: 626-564-3455
  Riverside
 Kaiser Permanente Medical Center - Riverside
 Han A Koh Ph: 626-564-3455
  Roseville
 Kaiser Permanente Medical Center - Roseville
 Louis Fehrenbacher Ph: 626-564-3455
  Sacramento
 Kaiser Permanente Medical Center - Sacramento
 Louis Fehrenbacher Ph: 626-564-3455
 South Sacramento Kaiser-Permanente Medical Center
 Louis Fehrenbacher Ph: 626-564-3455
 University of California Davis Cancer Center
 Helen K. Chew Ph: 916-734-3089
  Salinas
 Salinas Valley Memorial Hospital
 Laura V. Stampleman Ph: 831-759-1838
  Email: tnielsen2@svmh.com
  San Diego
 Kaiser Permanente Medical Center - Kaiser Foundation Hospital - San Diego
 Han A Koh Ph: 626-564-3455
 Kaiser Permanente Medical Office -Vandever Medical Office
 Han A Koh Ph: 626-564-3455
  San Francisco
 California Pacific Medical Center - California Campus
 Ari D Baron Ph: 650-696-4487
  Email: PazE@sutterhealth.org
 Kaiser Permanente Medical Center - San Francisco Geary Campus
 Louis Fehrenbacher Ph: 626-564-3455
  San Jose
 Kaiser Permanente Medical Center - Santa Teresa
 Louis Fehrenbacher Ph: 626-564-3455
 Santa Clara Valley Medical Center
 Sangeeta Aggarwal Ph: 718-904-2730
  Email: aecc@aecom.yu.edu
  San Marcos
 Kaiser Permanente Health Care
 Han A Koh Ph: 626-564-3455
  San Pablo
 Doctors Medical Center - San Pablo Campus
 James H. Feusner Ph: 510-450-7600
  San Rafael
 Kaiser Foundation Hospital - San Rafael
 Louis Fehrenbacher Ph: 626-564-3455
  Santa Clara
 Kaiser Permanente Medical Center - Santa Clara Homestead Campus
 Louis Fehrenbacher Ph: 626-564-3455
  Santa Rosa
 Kaiser Permanente Medical Center - Santa Rosa
 Louis Fehrenbacher Ph: 626-564-3455
 Sutter Pacific Medical Foundation
 Ari D Baron Ph: 650-696-4487
  Email: PazE@sutterhealth.org
  South San Francisco
 Kaiser Permanente Medical Center - South San Francisco
 Louis Fehrenbacher Ph: 626-564-3455
  Stockton
 Kaiser Permanente Medical Facility - Stockton
 Louis Fehrenbacher Ph: 626-564-3455
  Truckee
 Tahoe Forest Cancer Center
 Helen K. Chew Ph: 916-734-3089
  Vacaville
 Kaiser Permanente Medical Center - Vacaville
 Louis Fehrenbacher Ph: 626-564-3455
  Vallejo
 Kaiser Permanente Medical Center - Vallejo
 Louis Fehrenbacher Ph: 626-564-3455
 Sutter Solano Medical Center
 Ari D Baron Ph: 650-696-4487
  Email: PazE@sutterhealth.org
  Walnut Creek
 John Muir/Mt. Diablo Comprehensive Cancer Center
 Deborah L. Kerlin Ph: 925-674-2580
 Kaiser Permanente Medical Center - Walnut Creek
 Louis Fehrenbacher Ph: 626-564-3455
  Woodland Hills
 Kaiser Permanente Medical Cener - Woodland Hills
 Han A Koh Ph: 626-564-3455
Colorado
  Aurora
 University of Colorado Cancer Center at UC Health Sciences Center
 Anthony D. Elias Ph: 720-848-0650
  Colorado Springs
 Memorial Hospital Cancer Center - Colorado Springs
 Wendy S Oatis Ph: 719-365-2406
  Denver
 Kaiser Permanente of Colorado
 Alexander Menter Ph: 720-225-4203
  Fort Collins
 Front Range Cancer Specialists
 Diana C. Medgyesy Ph: 970-212-7600
 Poudre Valley Hospital
 Miho T Scott Ph: 970-495-8226
  Lafayette
 Kaiser Permanente - Lafayette
 Alexander Menter Ph: 720-225-4203
  Lone Tree
 Kaiser Permanente-Lone Tree
 Alexander Menter Ph: 720-225-4203
Connecticut
  Hartford
 Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
 Philip J. Stella Ph: 734-712-3456
  Middletown
 Middlesex Hospital Cancer Center
 Susanna Hong Ph: 860-358-2058
  New Haven
 Yale Cancer Center
 Maysa M Abu-Khalaf Ph: 203-785-5702
  Stamford
 Carl and Dorothy Bennett Cancer Center at Stamford Hospital
 Paul L Weinstein Ph: 203-323-8944
Delaware
  Lewes
 Tunnell Cancer Center at Beebe Medical Center
 Stephen Scott Grubbs Ph: 302-733-6227
  Newark
 Helen F. Graham Cancer Center at Christiana Hospital
 Stephen Scott Grubbs Ph: 302-733-6227
  Seaford
 Nanticoke Memorial Hospital
 Stephen Scott Grubbs Ph: 302-733-6227
District of Columbia
  Washington
 Kaiser Permanente at Capitol Hill Medical Center
 Leon C. Hwang Ph: 301-816-7446
 Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
 Claudine Isaacs Ph: 202-444-0381
 Veterans Affairs Medical Center - Washington, DC
 Anita Aggarwal Ph: 877-328-2621
 Washington Cancer Institute at Washington Hospital Center
 Claudine Isaacs Ph: 202-444-0381
Florida
  Daytona Beach
 Florida Hospital Memorial Medical Center
 Mudussara A Khan Ph: 386-676-6025
  Gainesville
 UF Health Cancer Center
 Karen C Daily Ph: 352-273-8675
  Email: trials@cancer.ufl.edu
  Miami
 University of Miami Sylvester Comprehensive Cancer Center - Miami
 Reshma L Mahtani Ph: 561-955-4800
  Orlando
 Florida Hospital Cancer Institute at Florida Hospital Orlando
 Lee M. Zehngebot Ph: 407-303-5623
 M.D. Anderson Cancer Center at Orlando
 Nikita C. Shah Ph: 321-841-7246
  Pensacola
 Sacred Heart Cancer Center at Sacred Heart Hospital
 Tarek Eldawy (Mohamed) Ph: 850-416-4611
 Sacred Heart Medical Oncology Group
 Tarek Eldawy (Mohamed) Ph: 850-416-4611
  Tampa
 H. Lee Moffitt Cancer Center and Research Institute at University of South Florida
 Martine Extermann Ph: 800-456-7121
  Email: canceranswers@moffitt.org
Georgia
  Decatur
 Charles B. Eberhart Cancer Center at DeKalb Medical Center
 Jayanthi Srinivasiah Ph: 404-501-3279
  Gainesville
 Northeast Georgia Medical Center
 Charles H. Nash Ph: 770-219-8800
  Email: cancerpatient.navigator@nghs.com
  Valdosta
 Pearlman Comprehensive Cancer Center at South Georgia Medical Center
 Jeffrey M. Hoy Ph: 229-259-4628
  Email: maryann.heddon@sgmc.org
Hawaii
  Aiea
 Kapiolani Medical Center at Pali Momi
 Jeffrey L. Berenberg Ph: 808-586-2979
 Jeffrey L. Berenberg Ph: 808-586-2979
  Honolulu
 Cancer Research Center of Hawaii
 Jeffrey L. Berenberg Ph: 808-586-2979
 Kaiser Permanente - Moanalua Medical Center and Clinic
 Louis Fehrenbacher Ph: 626-564-3455
 Kapiolani Medical Center for Women and Children
 Jeffrey L. Berenberg Ph: 808-586-2979
 OnCare Hawaii, Incorporated - Kuakini
 Jeffrey L. Berenberg Ph: 808-586-2979
 Jeffrey L. Berenberg Ph: 808-586-2979
 OnCare Hawaii, Incorporated - Lusitana
 Jeffrey L. Berenberg Ph: 808-586-2979
 Queen's Cancer Institute at Queen's Medical Center
 Jeffrey L. Berenberg Ph: 808-586-2979
 Straub Clinic and Hospital, Incorporated
 Jeffrey L. Berenberg Ph: 808-586-2979
  Kailua
 Castle Medical Center
 Jeffrey L. Berenberg Ph: 808-586-2979
  Lihue
 Kauai Medical Clinic
 Jeffrey L. Berenberg Ph: 808-586-2979
Idaho
  Boise
 Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center
 Philip J. Stella Ph: 734-712-3456
  Lewiston
 St. Joseph Regional Medical Center
 Yoshio Inoue Ph: 253-403-2394
  Post Falls
 Kootenai Cancer Center - Post Falls
 Benjamin Thomas Marchello Ph: 800-648-6274
Illinois
  Aurora
 Rush-Copley Cancer Care Center
 Maria T Grosse-Perdekamp Ph: 800-446-5532
  Email: kcheek@dmhhs.org
  Bloomington
 Illinois CancerCare - Bloomington
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 St. Joseph Medical Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Canton
 Illinois CancerCare - Canton
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Carthage
 Illinois CancerCare - Carthage
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Chicago
 Louis A. Weiss Memorial Hospital
 Keith L. Shulman Ph: 773-564-5044
 Resurrection Medical Center
 Christopher G. Rose Ph: 773-792-5116
 Robert H. Lurie Comprehensive Cancer Center at Northwestern University
 Sarika Jain Ph: 312-695-1301
  Email: cancer@northwestern.edu
 Rush Cancer Institute at Rush University Medical Center
 Melody A. Cobleigh Ph: 312-942-5498
  Email: clinical_trials@rush.edu
 Saint Joseph Hospital
 Ira Oliff Ph: 312-695-1301
  Email: cancer@northwestern.edu
 University of Chicago Cancer Research Center
 Olwen M Hahn Ph: 773-834-7424
 University of Illinois Cancer Center
 Oana C Danciu Ph: 312-355-3046
  Decatur
 Decatur Memorial Hospital Cancer Care Institute
 James L. Wade Ph: 217-876-4740
  Email: kcheek@dmhhs.org
  Elgin
 Sherman Hospital
 James L. Wade Ph: 217-876-4740
  Email: kcheek@dmhhs.org
  Eureka
 Illinois CancerCare - Eureka
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Galesburg
 Galesburg Clinic, PC
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 InterCommunity Cancer Center of Western Illinois
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Medical and Surgical Specialists, LLC
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Harvey
 Ingalls Cancer Care Center at Ingalls Memorial Hospital
 Mark F. Kozloff Ph: 708-915-4673
  Email: clinicaltrials@ingalls.org
  Highland Park
 Hematology Oncology Associates of Illinois-Highland Park
 Sarika Jain Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Kankakee
 Provena St. Mary's Regional Cancer Center - Kankakee
 Riaz Elahi Ph: 815-937-8780
  Kewanee
 Illinois CancerCare - Kewanee Clinic
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Libertyville
 North Shore Oncology and Hematology Associates, Limited - Libertyville
 Sarika Jain Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Macomb
 Illinois CancerCare - Macomb
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Maywood
 Cardinal Bernardin Cancer Center at Loyola University Medical Center
 Kathy S. Albain Ph: 708-226-4357
  Moline
 Garneau, Stewart C MD (UIA Investigator)
 Costas L. Constantinou Ph: 319-363-2690
 Porubcin, Michael MD (UIA Investigator)
 Costas L. Constantinou Ph: 319-363-2690
 Spector, David MD (UIA Investigator)
 Costas L. Constantinou Ph: 319-363-2690
 Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
 Costas L. Constantinou Ph: 319-363-2690
  Monmouth
 Illinois CancerCare - Monmouth
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Mount Vernon
 Good Samaritan Regional Health Center
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
  Naperville
 Hematology Oncology Consultants - Naperville
 Fariborze Behram Barhamand Ph: 630-369-1501
  Niles
 Cancer Care and Hematology Specialists of Chicagoland - Niles
 Sarika Jain Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Normal
 Community Cancer Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Ottawa
 Community Hospital of Ottawa
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois CancerCare - Ottawa
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Radiation Oncology of Northern Illinois
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Pekin
 Cancer Treatment Center at Pekin Hospital
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois CancerCare - Pekin
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Peoria
 CCOP - Illinois Oncology Research Association
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Illinois CancerCare - Peoria
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Methodist Medical Center of Illinois
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 OSF St. Francis Medical Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Proctor Hospital
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Peru
 Illinois CancerCare - Princeton
 Nguyet A Le-Lindqwister Ph: 800-793-2262
 Valley Cancer Center
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  Princeton
 Illinois CancerCare - Princeton
 Nguyet A Le-Lindqwister Ph: 800-793-2262
  River Forest
 West Suburban Center for Cancer Care
 Isoken Koko Ph: 708-488-0882
  Rockford
 Advanced Care and Treatment Medical Group, PC
 Harvey Eric Einhorn Ph: 779-696-9400
  Email: cancercare@swedishamerican.org
  Skokie
 Hematology Oncology Associates - Skokie
 Sarika Jain Ph: 312-695-1301
  Email: cancer@northwestern.edu
  Springfield
 Regional Cancer Center at Memorial Medical Center
 James L. Wade Ph: 217-876-4740
  Email: kcheek@dmhhs.org
  Urbana
 Carle Cancer Center at Carle Foundation Hospital
 Maria T Grosse-Perdekamp Ph: 800-446-5532
  Email: kcheek@dmhhs.org
Indiana
  Fort Wayne
 Fort Wayne Medical Oncology and Hematology
 Sreenivasa Rao Nattam Ph: 260-484-8830
  Email: ledgar@fwmoh.com
  Indianapolis
 Indiana University Melvin and Bren Simon Cancer Center
 Kathy Miller Ph: 317-274-2552
 St. Francis Hospital Cancer Care Services
 Howard M. Gross Ph: 765-983-3000
 William N. Wishard Memorial Hospital
 Kathy Miller Ph: 317-274-2552
  Michigan City
 Saint Anthony Memorial Health Centers
 Maria T Grosse-Perdekamp Ph: 800-446-5532
  Email: kcheek@dmhhs.org
  Munster
 Community Hospital
 Erwin L. Robin Ph: 708-915-4673
  Email: clinicaltrials@ingalls.org
  Richmond
 Reid Hospital & Health Care Services
 Howard M. Gross Ph: 765-983-3000
Iowa
  Ames
 McFarland Clinic, PC
 Joseph James Merchant Ph: 515-239-2621
  Bettendorf
 Constantinou, Costas L MD (UIA Investigator)
 Costas L. Constantinou Ph: 319-363-2690
 Hematology Oncology Associates of the Quad Cities
 Shobha R. Chitneni Ph: 563-355-7733
  Email: kedaprile@rccqc.com
  Clive
 Medical Oncology and Hematology Associates-West Des Moines
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Mercy Cancer Center - West Lakes
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
  Davenport
 Genesis Regional Cancer Center at Genesis Medical Center
 George Kovach Ph: 800-446-6088
  Email: werners@genesishealth.com
  Des Moines
 CCOP - Iowa Oncology Research Association
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 John Stoddard Cancer Center at Iowa Lutheran Hospital
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 John Stoddard Cancer Center at Iowa Methodist Medical Center
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Medical Oncology and Hematology Associates at John Stoddard Cancer Center
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Medical Oncology and Hematology Associates at Mercy Cancer Center
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Mercy Cancer Center at Mercy Medical Center - Des Moines
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
  Mason City
 Mercy Cancer Center at Mercy Medical Center - North Iowa
 Arvind Y Vemula Ph: 800-433-3883
  Ottumwa
 South Iowa Radiation Oncology Center at Ottumwa Regional Health Center
 Praveen Vikas Ph: 641-684-2742
  Sioux City
 Mercy Medical Center - Sioux City
 Donald Bruce Wender Ph: 712-252-0088
 Siouxland Hematology-Oncology Associates, LLP
 Donald Bruce Wender Ph: 712-252-0088
 St. Luke's Regional Medical Center
 Donald Bruce Wender Ph: 712-252-0088
  West Des Moines
 Methodist West Hospital
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
 Robert J Behrens Ph: 888-244-6061
  Email: sherrijr@iora.org
Kansas
  Chanute
 Cancer Center of Kansas, PA - Chanute
 Shaker R. Dakhil Ph: 316-262-4467
  Dodge City
 Cancer Center of Kansas, PA - Dodge City
 Shaker R. Dakhil Ph: 316-262-4467
  El Dorado
 Cancer Center of Kansas, PA - El Dorado
 Shaker R. Dakhil Ph: 316-262-4467
  Fort Scott
 Cancer Center of Kansas - Fort Scott
 Shaker R. Dakhil Ph: 316-262-4467
  Independence
 Cancer Center of Kansas-Independence
 Shaker R. Dakhil Ph: 316-262-4467
  Kingman
 Cancer Center of Kansas, PA - Kingman
 Shaker R. Dakhil Ph: 316-262-4467
  Lawrence
 Lawrence Memorial Hospital
 Shaker R. Dakhil Ph: 316-262-4467
  Liberal
 Cancer Center of Kansas, PA - Liberal
 Shaker R. Dakhil Ph: 316-262-4467
  McPherson
 Cancer Center of Kansas, PA - McPherson
 Shaker R. Dakhil Ph: 316-262-4467
  Newton
 Cancer Center of Kansas, PA - Newton
 Shaker R. Dakhil Ph: 316-262-4467
  Parsons
 Cancer Center of Kansas, PA - Parsons
 Shaker R. Dakhil Ph: 316-262-4467
  Pratt
 Cancer Center of Kansas, PA - Pratt
 Shaker R. Dakhil Ph: 316-262-4467
  Salina
 Cancer Center of Kansas, PA - Salina
 Shaker R. Dakhil Ph: 316-262-4467
  Wellington
 Cancer Center of Kansas, PA - Wellington
 Shaker R. Dakhil Ph: 316-262-4467
  Wichita
 Associates in Women's Health, PA - North Hillside
 Shaker R. Dakhil Ph: 316-262-4467
 Cancer Center of Kansas, PA - Medical Arts Tower
 Shaker R. Dakhil Ph: 316-262-4467
 Cancer Center of Kansas, PA - Wichita
 Shaker R. Dakhil Ph: 316-262-4467
 CCOP - Wichita
 Shaker R. Dakhil Ph: 316-262-4467
 Via Christi Cancer Center at Via Christi Regional Medical Center
 Shaker R. Dakhil Ph: 316-262-4467
 Wesley Medical Center
 Shaker R. Dakhil Ph: 316-262-4467
  Winfield
 Cancer Center of Kansas, PA - Winfield
 Shaker R. Dakhil Ph: 316-262-4467
Kentucky
  Ashland
 Cancer Resource Center at King's Daughters Medical Center
 David K. Goebel Ph: 888-823-5923
  Email: ctsucontact@westat.com
  Lexington
 Central Baptist Hospital
 Lee G. Hicks Ph: 859-260-6425
 University of Kentucky Chandler Medical Center
 Suleiman A Massarweh Ph: 859-257-3379
  Louisville
 Baptist Hospital East - Louisville
 Udaya G. Joseph Ph: 502-897-8592
  Email: Cbcresearch@bhsi.com
Louisiana
  Baton Rouge
 Ochsner Health Center - Bluebonnet
 John T Cole Ph: 888-562-4763
  New Orleans
 Ochsner Cancer Institute at Ochsner Clinic Foundation
 John T Cole Ph: 888-562-4763
  Shreveport
 Christus Schumpert Cancer Treatment Center
 Neelima Chintapalli Ph: 318-681-4763
Maine
  Augusta
 Harold Alfond Center for Cancer Care
 Thomas Henry Openshaw Ph: 207-973-4274
  Bangor
 CancerCare of Maine at Eastern Maine Medical Center
 Thomas Henry Openshaw Ph: 207-973-4274
  Rockport
 Penobscot Bay Medical Center Cancer Care Center
 Thomas Henry Openshaw Ph: 207-973-4274
  York
 York Hospital's Oncology Treatment Center
 Jonathan D Eneman Ph: 207-351-3777
Maryland
  Annapolis
 DeCesaris Cancer Institute at Anne Arundel Medical Center
 Carol K Tweed Ph: 800-474-9892
  Baltimore
 Alvin and Lois Lapidus Cancer Institute at Sinai Hospital
 Mayer Gorbaty Ph: 410-601-6120
  Email: pridgely@lifebridgehealth.org
 Harry and Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
 Claudine Isaacs Ph: 202-444-0381
 Kaiser Permanente at Woodlawn Medical Center
 Leon C. Hwang Ph: 301-816-7446
 Mercy Medical Center
 David A. Riseberg Ph: 410-951-7950
  Email: prc@mdmercy.com
 Union Memorial Hospital
 Claudine Isaacs Ph: 202-444-0381
  Bethesda
 Suburban Hospital
 Carolyn Bennett Hendricks Ph: 301-896-2719
  Email: Bsquiller@suburbanhospital.org
  Frederick
 Frederick Memorial Hospital Regional Cancer Therapy Center
 Brian M. O'Connor Ph: 240-566-3584
  Email: clinicaltrials@fmh.org
  Gaithersburg
 Kaiser Permanente - Gaithersburg Medical Center
 Leon C. Hwang Ph: 301-816-7446
  Largo
 Kaiser Permanente Mid-Atlantic Medical Group-Largo Medical Facility
 Leon C. Hwang Ph: 301-816-7446
  Randallstown
 Northwest Hospital Center
 Mayer Gorbaty Ph: 410-601-6120
  Email: pridgely@lifebridgehealth.org
  Silver Spring
 Holy Cross Hospital
 Cheryl A. Aylesworth Ph: 301-896-2719
  Email: Bsquiller@suburbanhospital.org
Massachusetts
  Beverly
 Beverly Hospital
 Angus P. McIntyre Ph: 978-283-4000ext559
  Burlington
 Lahey Clinic Medical Center - Burlington
 Corrine L Zarwan Ph: 781-744-8027
  Gloucester
 Addison Gilbert Hospital
 Angus P. McIntyre Ph: 978-283-4000ext559
  Lowell
 Lowell General Hospital
 Blair Ardman Ph: 978-788-7084
  Email: ghincks@lowellgeneral.org
  Newton
 Newton-Wellesley Hospital
 Caroline C Block Ph: 888-823-5923
  Email: ctsucontact@westat.com
  Quincy
 Commonwealth Hematology-Oncology, PC - Quincy
 James R. Everett Ph: 781-337-9091
Michigan
  Adrian
 Hickman Cancer Center at Bixby Medical Center
 Rex B Mowat Ph: 517-265-0116
 Rex B Mowat Ph: 517-265-0116
  Ann Arbor
 CCOP - Michigan Cancer Research Consortium
 Philip J. Stella Ph: 734-712-3456
 Saint Joseph Mercy Cancer Center
 Philip J. Stella Ph: 734-712-3456
 University of Michigan Comprehensive Cancer Center
 Anne F. Schott Ph: 800-865-1125
  Battle Creek
 Battle Creek Health System Cancer Care Center
 Gilbert D Padula Ph: 616-685-5225
  Bay City
 Bay Regional Medical Center
 Justin F Klamerus Ph: 800-248-6777
  Clarkston
 Great Lakes Cancer Institute
 Justin F Klamerus Ph: 800-248-6777
  Dearborn
 Oakwood Cancer Center at Oakwood Hospital and Medical Center
 Philip J. Stella Ph: 734-712-3456
  Detroit
 Josephine Ford Cancer Center at Henry Ford Hospital
 Robert Anthony Chapman Ph: 313-916-1784
 Van Elslander Cancer Center at St. John Hospital and Medical Center
 Philip J. Stella Ph: 734-712-3456
 Wayne State University
 Lawrence E. Flaherty Ph: 313-576-9363
  Escanaba
 Green Bay Oncology, Limited - Escanaba
 Matthew L Ryan Ph: 800-432-6049
  Farmington Hills
 Weisberg Cancer Treatment Center
 Lawrence E. Flaherty Ph: 313-576-9363
  Flint
 Genesys Hurley Cancer Institute
 Philip J. Stella Ph: 734-712-3456
 Hurley Medical Center
 Philip J. Stella Ph: 734-712-3456
 McLaren Cancer Institute
 Justin F Klamerus Ph: 800-248-6777
 Singh and Arora Hematology Oncology, PC
 Justin F Klamerus Ph: 800-248-6777
  Grand Rapids
 Butterworth Hospital at Spectrum Health
 Gilbert D Padula Ph: 616-685-5225
 CCOP - Grand Rapids
 Gilbert D Padula Ph: 616-685-5225
 Lacks Cancer Center at Saint Mary's Health Care
 Gilbert D Padula Ph: 616-685-5225
  Iron Mountain
 Green Bay Oncology - Iron Mountain
 Matthew L Ryan Ph: 800-432-6049
  Jackson
 Gayle M. Jacob Cancer Center at Allegiance Health
 Philip J. Stella Ph: 734-712-3456
  Kalamazoo
 Borgess Medical Center
 Raymond Sterling Lord Ph: 269-373-7458
 Bronson Methodist Hospital
 Raymond Sterling Lord Ph: 269-373-7458
 West Michigan Cancer Center
 Raymond Sterling Lord Ph: 269-373-7458
  Lansing
 Sparrow Regional Cancer Center
 Philip J. Stella Ph: 734-712-3456
  Lapeer
 Great Lakes Cancer Institute - Lapeer Campus
 Justin F Klamerus Ph: 800-248-6777
  Livonia
 St. Mary Mercy Hospital
 Philip J. Stella Ph: 734-712-3456
  Marquette
 Upper Michigan Cancer Center at Marquette General Hospital
 Amy Weise Ph: 313-576-9363
  Monroe
 Community Cancer Center of Monroe
 Rex B Mowat Ph: 517-265-0116
 Mercy Memorial Hospital - Monroe
 Rex B Mowat Ph: 517-265-0116
  Mount Clemens
 Clemens Regional Medical Center
 Justin F Klamerus Ph: 800-248-6777
  Mount Pleasant
 Norval K. Morey Cancer Center at Central Michigan Community Hospital
 Justin F Klamerus Ph: 800-248-6777
  Muskegon
 Mercy General Health Partners
 Gilbert D Padula Ph: 616-685-5225
  Petoskey
 Northern Michigan Hospital
 Justin F Klamerus Ph: 800-248-6777
  Pontiac
 St. Joseph Mercy Oakland
 Philip J. Stella Ph: 734-712-3456
  Port Huron
 Mercy Regional Cancer Center at Mercy Hospital
 Philip J. Stella Ph: 734-712-3456
  Reed City
 Spectrum Health Reed City Hospital
 Gilbert D Padula Ph: 616-685-5225
  Royal Oak
 William Beaumont Hospital - Royal Oak Campus
 Padmaja V Venuturumilli Ph: 248-551-7695
  Saginaw
 Seton Cancer Institute at Saint Mary's - Saginaw
 Philip J. Stella Ph: 734-712-3456
  Southfield
 Providence Hospital - Southfield
 Anibal Drelichman Ph: 248-849-5337
  Email: jaswinder.grewal@stjohn.org
  Traverse City
 Munson Medical Center
 Gilbert D Padula Ph: 616-685-5225
  Troy
 William Beaumont Hospital - Troy Campus
 Padmaja V Venuturumilli Ph: 248-551-7695
  Warren
 St. John Macomb Hospital
 Philip J. Stella Ph: 734-712-3456
Minnesota
  Bemidji
 MeritCare Bemidji
 Preston D. Steen Ph: 701-234-6161
  Brainerd
 St. Joseph's Medical Center
 Daniel Nikcevich Ph: 888-203-7267
  Burnsville
 Fairview Ridges Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Coon Rapids
 Mercy and Unity Cancer Center at Mercy Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Duluth
 CCOP - Duluth
 Daniel Nikcevich Ph: 888-203-7267
 Essentia Health - Duluth Clinic
 Daniel Nikcevich Ph: 888-203-7267
 Miller - Dwan Medical Center
 Daniel Nikcevich Ph: 888-203-7267
 St. Luke's Hospital Cancer Care Center
 Basem S Goueli Ph: 888-823-5923
  Email: ctsucontact@westat.com
  Edina
 Fairview Southdale Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Fergus Falls
 Lake Region Healthcare Corporation-Cancer Care
 Daniel Nikcevich Ph: 888-203-7267
  Fridley
 Mercy and Unity Cancer Center at Unity Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Hutchinson
 Hutchinson Area Health Care
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Mankato
 Immanuel St. Joseph's
 Mohmmad J Ranginwala Ph: 507-385-2929
  Maplewood
 HealthEast Cancer Care at St. John's Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
 Minnesota Oncology - Maplewood
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Minneapolis
 Hennepin County Medical Center - Minneapolis
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
 Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  New Ulm
 New Ulm Medical Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Robbinsdale
 Humphrey Cancer Center at North Memorial Outpatient Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Rochester
 Mayo Clinic Cancer Center
 Matthew P. Goetz Ph: 507-538-7623
  Saint Cloud
 CentraCare Clinic - Women and Children
 Donald J Jurgens Ph: 877-229-4907
  Email: coborncancercenter@centracare.com
 Coborn Cancer Center
 Donald J Jurgens Ph: 877-229-4907
  Email: coborncancercenter@centracare.com
  Saint Louis Park
 CCOP - Metro-Minnesota
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
 Park Nicollet Cancer Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Saint Paul
 Regions Hospital Cancer Care Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
 United Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Shakopee
 St. Francis Cancer Center at St. Francis Medical Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Stillwater
 Lakeview Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Waconia
 Ridgeview Medical Center
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Willmar
 Willmar Cancer Center at Rice Memorial Hospital
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Woodbury
 Minnesota Oncology - Woodbury
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
Mississippi
  Jackson
 University of Mississippi Cancer Clinic
 Barbara S Craft Ph: 601-815-6700
Missouri
  Bolivar
 Central Care Cancer Center at Carrie J. Babb Cancer Center
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
  Branson
 Skaggs Cancer Center at Skaggs Regional Medical Center
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
  Cape Girardeau
 Saint Francis Medical Center
 James L. Wade Ph: 217-876-4740
  Email: kcheek@dmhhs.org
 Southeast Cancer Center
 Alan Philip Lyss Ph: 800-392-0936
  Chesterfield
 Saint Luke's Hospital
 Donald F. Busiek Ph: 314-205-6936
  Columbia
 Ellis Fischel Cancer Center at University of Missouri - Columbia
 Donald C Doll Ph: 573-882-7440
  Jefferson City
 Goldschmidt Cancer Center
 Alan Philip Lyss Ph: 800-392-0936
  Joplin
 Freeman Cancer Institute at Freeman Health System
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
 St. John's Regional Medical Center
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
  Rolla
 Mercy Clinic Cancer and Hematology - Rolla
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
 Phelps County Regional Medical Center
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
  Saint Louis
 David C. Pratt Cancer Center at St. John's Mercy
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
 Mercy Clinic St. Louis Cancer and Breast Institute
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
 Missouri Baptist Cancer Center
 Alan Philip Lyss Ph: 800-392-0936
 Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
 Michael J. Naughton Ph: 800-600-3606
  Email: info@siteman.wustl.edu
  Springfield
 Hulston Cancer Center at Cox Medical Center South
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
 St. John's Regional Health Center
 Jay W Carlson Ph: 888-244-6061
  Email: sherrijr@iora.org
Montana
  Billings
 Billings Clinic Cancer Center - 801 N 29th Street
 Benjamin Thomas Marchello Ph: 800-648-6274
 CCOP - Montana Cancer Consortium
 Benjamin Thomas Marchello Ph: 800-648-6274
 St. Vincent Healthcare Cancer Care Services
 Benjamin Thomas Marchello Ph: 800-648-6274
  Bozeman
 Bozeman Deaconess Cancer Center
 Benjamin Thomas Marchello Ph: 800-648-6274
  Butte
 St. James Healthcare Cancer Care
 Benjamin Thomas Marchello Ph: 800-648-6274
  Great Falls
 Benefis Sletten Cancer Institute
 Benjamin Thomas Marchello Ph: 800-648-6274
 Great Falls Clinic - Main Facility
 Benjamin Thomas Marchello Ph: 800-648-6274
  Helena
 St. Peter's Hospital
 Benjamin Thomas Marchello Ph: 800-648-6274
  Kalispell
 Kalispell Regional Medical Center
 Benjamin Thomas Marchello Ph: 800-648-6274
  Missoula
 Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
 Benjamin Thomas Marchello Ph: 800-648-6274
 Montana Cancer Specialists at Montana Cancer Center
 Benjamin Thomas Marchello Ph: 800-648-6274
Nebraska
  Kearney
 Good Samaritan Cancer Center at Good Samaritan Hospital
 George K. Bascom Ph: 308-865-7963
  Lincoln
 Cancer Resource Center - Lincoln
 Gamini S. Soori Ph: 800-253-4368
  Omaha
 Alegant Health Cancer Center at Bergan Mercy Medical Center
 Gamini S. Soori Ph: 800-253-4368
 CCOP - Missouri Valley Cancer Consortium
 Gamini S. Soori Ph: 800-253-4368
 Creighton University Medical Center
 Gamini S. Soori Ph: 800-253-4368
 Immanuel Medical Center
 Gamini S. Soori Ph: 800-253-4368
 Lakeside Hospital
 Gamini S. Soori Ph: 800-253-4368
 Methodist Estabrook Cancer Center
 Robert M. Langdon Ph: 402-354-5144
Nevada
  Carson City
 Carson Tahoe Cancer Center at Carson Tahoe Regional Medical Center
 John P Kelly Ph: 702-384-0013
  Henderson
 21st Century Oncology - Henderson
 John Allan Ellerton Ph: 702-384-0013
 Cancer and Blood Specialists-Henderson
 John Allan Ellerton Ph: 702-384-0013
  Las Vegas
 21st Century Oncology - Fort Apache
 John Allan Ellerton Ph: 702-384-0013
 21st Century Oncology - Vegas Sunrise
 John Allan Ellerton Ph: 702-384-0013
 21st Century Oncology - Vegas Tenaya
 John Allan Ellerton Ph: 702-384-0013
 Cancer and Blood Specialists-Fort Apache
 John Allan Ellerton Ph: 702-384-0013
 Cancer and Blood Specialists-Shadow
 John Allan Ellerton Ph: 702-384-0013
 Cancer Institute of Nevada at Summerlin Hospital Medical Center
 John Allan Ellerton Ph: 702-384-0013
 CCOP - Nevada Cancer Research Foundation
 John Allan Ellerton Ph: 702-384-0013
 Comprehensive Cancer Centers of Nevada - Central Valley
 John Allan Ellerton Ph: 702-384-0013
 Comprehensive Cancer Centers of Nevada - Northwest
 John Allan Ellerton Ph: 702-384-0013
 Comprehensive Cancer Centers of Nevada - Southwest
 John Allan Ellerton Ph: 702-384-0013
 HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
 John Allan Ellerton Ph: 702-384-0013
 HealthCare Partners Medical Group Oncology/Hematology-San Martin
 John Allan Ellerton Ph: 702-384-0013
 HealthCare Partners Medical Group Oncology/Hematology-Tenaya
 John Allan Ellerton Ph: 702-384-0013
 Las Vegas Cancer Center-Medical Center
 John Allan Ellerton Ph: 702-384-0013
 Radiation Oncology Centers of Las Vegas - Downtown Location
 John Allan Ellerton Ph: 702-384-0013
 University Medical Center of Southern Nevada
 John Allan Ellerton Ph: 702-384-0013
New Hampshire
  Concord
 New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
 Douglas Jay Weckstein Ph: 603-224-2556
  Hooksett
 New Hampshire Oncology - Hematology, PA - Hooksett
 Douglas Jay Weckstein Ph: 603-224-2556
  Laconia
 Lakes Region General Hospital
 Douglas Jay Weckstein Ph: 603-224-2556
  Lebanon
 Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
 Gary N Schwartz Ph: 800-639-6918
  Email: cancer.research.nurse@dartmouth.edu
New Jersey
  Camden
 Cancer Institute of New Jersey at Cooper University Hospital - Camden
 Stephen Scott Grubbs Ph: 302-733-6227
  Englewood
 Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center
 Jill S Morrison Ph: 201-894-3456
  Mount Holly
 Virtua Fox Chase Health Cancer Program at Virtua Memorial Hospital Burlington County
 Michael S. Entmacher Ph: 888-847-8823
  New Brunswick
 Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
 Deborah L. Toppmeyer Ph: 732-235-8675
  Ridgewood
 Valley Hospital - Ridgewood
 Eli D Kirshner Ph: 201-634-5792
  Email: cparish@valleyhealth.com
  Sewell
 Radiation Oncology Center at Kennedy Health System - Sewell
 Trina A Poretta Ph: 888-847-8823
  Somerville
 Somerset Medical Center
 Kathleen C Toomey Ph: 908-685-2481
  Sparta
 Frederick R. and Betty M. Smith Cancer Treatment Center
 Allison Zibelli Ph: 215-955-6084
  Voorhees
 Fox Chase Virtua Health Cancer Program at Virtua West Jersey
 Michael S. Entmacher Ph: 888-847-8823
New Mexico
  Albuquerque
 Hematology Oncology Associates, PC
 Melanie E. Royce Ph: 505-727-8000
 Presbyterian Cancer Treatment Center at Presbyterian Kaseman Hospital
 Melanie E. Royce Ph: 505-727-8000
 University of New Mexico Cancer Center
 Melanie E. Royce Ph: 505-727-8000
  Las Cruces
 Memorial Medical Center
 Melanie E. Royce Ph: 505-727-8000
  Santa Fe
 New Mexico Cancer Care Associates
 Melanie E. Royce Ph: 505-727-8000
New York
  Bronx
 Jack D. Weiler Hospital at Montefiore Medical Center - East Campus
 Della F Makower Ph: 718-904-2730
  Email: aecc@aecom.yu.edu
 Montefiore Medical Center
 Della F Makower Ph: 718-904-2730
  Email: aecc@aecom.yu.edu
  Buffalo
 Roswell Park Cancer Institute
 Ellis G. Levine Ph: 877-275-7724
  East Syracuse
 CCOP - Hematology-Oncology Associates of Central New York
 Jeffrey J. Kirshner Ph: 315-472-7504
  Elmira
 Falck Cancer Center at Arnot Ogden Medical Center
 Jonathan W Friedberg Ph: 585-275-5830
  Lake Success
 Monter Cancer Center of the North Shore-LIJ Health System
 Lora R. Weiselberg Ph: 516-562-3467
  Manhasset
 Don Monti Comprehensive Cancer Center at North Shore University Hospital
 Lora R. Weiselberg Ph: 516-562-3467
  New Hyde Park
 Long Island Jewish Medical Center
 Lora R. Weiselberg Ph: 516-562-3467
  New York
 Beth Israel Medical Center - Petrie Division
 Paula Klein Ph: 212-367-1729
 Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center
 Dawn Hershman Ph: 212-305-8615
 New York University Medical Center
 Yelena Novik Ph: 212-263-4434
  Email: prmc.coordinator@nyumc.org
 New York Weill Cornell Cancer Center at Cornell University
 Ellen Chuang Ph: 212-746-1848
 St. Luke's - Roosevelt Hospital Center - St.Luke's Division
 Paula Klein Ph: 212-367-1729
  Rochester
 Daisy Marquis Jones Radiation Oncology Center at Highland Hospital of Rochester
 Jonathan W Friedberg Ph: 585-275-5830
 James P. Wilmot Cancer Center at University of Rochester Medical Center
 Jonathan W Friedberg Ph: 585-275-5830
 Lipson Cancer and Blood Center at Rochester General Hospital
 Peter Bushunow Ph: 585-922-3536
  Email: tia.derosa@rochestergeneral.org
North Carolina
  Asheboro
 Randolph Hospital
 Peter Rubin Ph: 336-832-0821
  Asheville
 Mission Hospitals - Memorial Campus
 Christopher H Chay Ph: 828-213-4150
  Chapel Hill
 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
 Katherine E Reeder-Hayes Ph: 877-668-0683
  Email: cancerclinicaltrials@med.unc.edu
  Goldsboro
 Wayne Memorial Hospital, Incorporated
 James N. Atkins Ph: 919-580-0000
  Greensboro
 Moses Cone Regional Cancer Center at Wesley Long Community Hospital
 Peter Rubin Ph: 336-832-0821
  Hendersonville
 Comprehensive Cancer Center at Pardee Hospital
 James E. Radford Ph: 828-696-4716
 Park Ridge Hospital Breast Health Center
 James Dewitt Bearden Ph: 800-486-5941
  Pinehurst
 FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center
 Charles S Kuzma Ph: 910-715-2200
  Raleigh
 Rex Cancer Center at Rex Hospital
 JoEllen C Speca Ph: 919-784-7209
 Rex Cancer Center of Wakefield
 JoEllen C Speca Ph: 919-784-7209
  Reidsville
 Annie Penn Cancer Center
 Peter Rubin Ph: 336-832-0821
  Statesville
 Iredell Memorial Hospital
 Ruby A. Grimm Ph: 704-873-5661
  Washington
 Marion L. Shepard Cancer Center at Beaufort County Hospital
 John J Inzerillo Ph: 252-975-4308ext104
  Email: sbell@brhealthsystem.org
North Dakota
  Bismarck
 Medcenter One Hospital Cancer Care Center
 Preston D. Steen Ph: 701-234-6161
  Fargo
 Roger Maris Cancer Center at MeritCare Hospital
 Preston D. Steen Ph: 701-234-6161
 Preston D. Steen Ph: 701-234-6161
 Sanford Clinic North-Fargo
 Preston D. Steen Ph: 701-234-6161
  Grand Forks
 Altru Cancer Center at Altru Hospital
 Grant R Seeger Ph: 701-780-6520
  Minot
 Trinity CancerCare Center
 Patanit Watanaboonyakhet Ph: 800-862-0005
Ohio
  Akron
 McDowell Cancer Center at Akron General Medical Center
 Esther H. Rehmus Ph: 330-344-6348
 Summa Center for Cancer Care at Akron City Hospital
 Jennifer E Payne Ph: 330-375-6101
  Barberton
 Barberton Citizens Hospital
 Jennifer E Payne Ph: 330-375-6101
  Beachwood
 Cleveland Clinic Taussig Cancer Center
 Anjali S Advani Ph: 866-223-8100
  Belpre
 Strecker Cancer Center-Belpre
 J. Philip Kuebler Ph: 800-446-5532
  Bowling Green
 Wood County Oncology Center
 Rex B Mowat Ph: 517-265-0116
  Chillicothe
 Adena Regional Medical Center
 J. Philip Kuebler Ph: 614-566-3275
  Cincinnati
 Christ Hospital Cancer Center
 Jennifer B Manders Ph: 513-585-2859
 University of Cincinnati
 John Charles Morris Ph: 513-558-4553
  Email: uchealthnews@uc.edu
  Cleveland
 Case Comprehensive Cancer Center
 Joseph Baar Ph: 800-641-2422
 Cleveland Clinic Cancer Center at Fairview Hospital
 Anjali S Advani Ph: 866-223-8100
 Cleveland Clinic Taussig Cancer Center
 Anjali S Advani Ph: 866-223-8100
 MetroHealth Cancer Care Center at MetroHealth Medical Center
 Bruce J. Averbook Ph: 216-778-8526
  Email: kbauchens@metrohealth.org
  Columbus
 CCOP - Columbus
 J. Philip Kuebler Ph: 614-566-3275
 Columbus Oncology Associates, Incorporated
 J. Philip Kuebler Ph: 800-446-5532
 Doctors Hospital at Ohio Health
 J. Philip Kuebler Ph: 614-566-3275
 Grant Medical Center Cancer Care
 J. Philip Kuebler Ph: 614-566-3275
 Mount Carmel Health - West Hospital
 J. Philip Kuebler Ph: 614-566-3275
 Riverside Methodist Hospital Cancer Care
 J. Philip Kuebler Ph: 614-566-3275
 Zangmeister Center
 J. Philip Kuebler Ph: 614-566-3275
  Dayton
 CCOP - Dayton
 Howard M. Gross Ph: 765-983-3000
 David L. Rike Cancer Center at Miami Valley Hospital
 Howard M. Gross Ph: 765-983-3000
 Good Samaritan Hospital
 Howard M. Gross Ph: 765-983-3000
 Grandview Hospital
 Howard M. Gross Ph: 765-983-3000
 Samaritan North Cancer Care Center
 Howard M. Gross Ph: 765-983-3000
  Delaware
 Delaware Health Center
 J. Philip Kuebler Ph: 800-446-5532
 Grady Memorial Hospital
 J. Philip Kuebler Ph: 614-566-3275
  Findlay
 Blanchard Valley Regional Cancer Center
 Howard M. Gross Ph: 765-983-3000
  Franklin
 Atrium Medical Center
 Howard M. Gross Ph: 765-983-3000
  Greenville
 Wayne Hospital
 Howard M. Gross Ph: 765-983-3000
  Independence
 Cleveland Clinic Taussig Cancer Center
 Anjali S Advani Ph: 866-223-8100
  Kettering
 Charles F. Kettering Memorial Hospital
 Howard M. Gross Ph: 765-983-3000
  Lancaster
 Fairfield Medical Center
 J. Philip Kuebler Ph: 614-566-3275
  Lima
 Lima Memorial Hospital
 Rex B Mowat Ph: 517-265-0116
 St. Rita's Medical Center
 Henry Gerad Ph: 419-226-9617
  Marietta
 Strecker Cancer Center at Marietta Memorial Hospital
 J. Philip Kuebler Ph: 614-566-3275
  Maumee
 Northwest Ohio Oncology Center
 Rex B Mowat Ph: 517-265-0116
 Rex B Mowat Ph: 517-265-0116
  Mayfield Heights
 Hillcrest Cancer Center at Hillcrest Hospital
 Anjali S Advani Ph: 866-223-8100
  Mount Vernon
 Knox Community Hospital
 J. Philip Kuebler Ph: 614-566-3275
  Newark
 Licking Memorial Cancer Care Program at Licking Memorial Hospital
 J. Philip Kuebler Ph: 614-566-3275
  Oregon
 St. Charles Mercy Hospital
 Rex B Mowat Ph: 517-265-0116
 Toledo Clinic - Oregon
 Rex B Mowat Ph: 517-265-0116
  Portsmouth
 Southern Ohio Medical Center Cancer Center
 J. Philip Kuebler Ph: 614-566-3275
  Sandusky
 North Coast Cancer Care, Incorporated
 Anjali S Advani Ph: 866-223-8100
  Springfield
 Community Hospital of Springfield and Clark County
 J. Philip Kuebler Ph: 614-566-3275
  Strongsville
 Cleveland Clinic Foundation - Strongsville
 Anjali S Advani Ph: 866-223-8100
  Sylvania
 Flower Hospital Cancer Center
 Rex B Mowat Ph: 517-265-0116
  Tiffin
 Mercy Hospital of Tiffin
 Rex B Mowat Ph: 517-265-0116
  Toledo
 CCOP - Toledo Community Hospital
 Rex B Mowat Ph: 517-265-0116
 St. Anne Mercy Hospital
 Rex B Mowat Ph: 517-265-0116
 St. Vincent Mercy Medical Center
 Rex B Mowat Ph: 517-265-0116
 Toledo Clinic, Incorporated - Main Clinic
 Rex B Mowat Ph: 517-265-0116
 Toledo Hospital
 Rex B Mowat Ph: 517-265-0116
 University of Toledo Medical Center
 Rex B Mowat Ph: 517-265-0116
  Troy
 UVMC Cancer Care Center at Upper Valley Medical Center
 Howard M. Gross Ph: 765-983-3000
  Wauseon
 Fulton County Health Center
 Rex B Mowat Ph: 517-265-0116
  West Chester
 University Pointe
 John Charles Morris Ph: 513-558-4553
  Email: uchealthnews@uc.edu
  Westerville
 Mount Carmel St. Ann's Cancer Center
 J. Philip Kuebler Ph: 614-566-3275
  Wooster
 Cleveland Clinic - Wooster
 Anjali S Advani Ph: 866-223-8100
  Wright-Patterson Afb
 United States Air Force Medical Center - Wright-Patterson
 Brandon J Cutler Ph: 937-257-1398
  Xenia
 Ruth G. McMillan Cancer Center at Greene Memorial Hospital
 Howard M. Gross Ph: 765-983-3000
  Zanesville
 Genesis - Good Samaritan Hospital
 J. Philip Kuebler Ph: 614-566-3275
Oklahoma
  Lawton
 Cancer Centers of Southwest Oklahoma, LLC - Lawton
 Nadim F. Nimeh Ph: 877-231-4440
  Norman
 Cancer Care Associates - Norman
 Vikki Ann Canfield Ph: 405-271-4272
  Email: julie-traylor@ouhsc.edu
  Oklahoma City
 Cancer Care Associates - Mercy Campus
 Vikki Ann Canfield Ph: 405-271-4272
  Email: julie-traylor@ouhsc.edu
 Oklahoma University Cancer Institute
 George B Selby Ph: 405-271-4272
  Email: julie-traylor@ouhsc.edu
  Tulsa
 Cancer Care Associates-Yale
 George B Selby Ph: 405-271-4272
  Email: julie-traylor@ouhsc.edu
 Natalie Warren Bryant Cancer Center at St. Francis Hospital
 Joseph P. Lynch Ph: 918-494-2200
Oregon
  Bend
 St. Charles Medical Center - Bend
 Robert Boone Ph: 541-706-2659
  Clackamas
 Clackamas Radiation Oncology Center
 Alison K Conlin Ph: 503-215-6412
  Coos Bay
 Bay Area Hospital
 Bret A. Cook Ph: 541-269-8392
  Email: cherie.cox@bayareahospital.org
  Grants Pass
 Three Rivers Community Hospital
 Charles R. Dibb Ph: 541-789-6176
  Gresham
 Legacy Mount Hood Medical Center
 Jacqueline Vuky Ph: 503-299-6500
  Medford
 Dubs Cancer Center at Rogue Valley Medical Center
 Charles R. Dibb Ph: 541-789-6176
 Providence Cancer Center at PMCC
 Charles R. Dibb Ph: 541-789-6176
  Milwaukie
 Providence Milwaukie Hospital
 Alison K Conlin Ph: 503-215-6412
  Newberg
 Providence Newberg Medical Center
 Alison K Conlin Ph: 503-215-6412
  Oregon City
 Willamette Falls Hospital
 Alison K Conlin Ph: 503-215-6412
  Portland
 CCOP - Columbia River Oncology Program
 Alison K Conlin Ph: 503-215-6412
 Kaiser Permanente Health Care - Portland
 Nagendra Tirumali Ph: 503-335-2400
 Legacy Good Samaritan Hospital & Comprehensive Cancer Center
 Jacqueline Vuky Ph: 503-299-6500
 Providence Cancer Center at Providence Portland Medical Center
 Alison K Conlin Ph: 503-215-6412
 Providence St. Vincent Medical Center
 Alison K Conlin Ph: 503-215-6412
  Salem
 Salem Hospital Regional Cancer Care Services
 John Strother Ph: 503-561-2618
  Tualatin
 Legacy Meridian Park Hospital
 Jacqueline Vuky Ph: 503-299-6500
Pennsylvania
  Bethlehem
 St. Luke's Cancer Network at St. Luke's Hospital
 Hikaru Nakajima Ph: 610-954-3582
  Email: infolink@slhn.org
  Bryn Mawr
 Bryn Mawr Hospital
 Albert S DeNittis Ph: 866-225-5654
  Danville
 Geisinger Cancer Institute at Geisinger Health
 Victor Gerald Vogel Ph: 570-271-5251
  Drexel Hill
 Delaware County Regional Cancer Center at Delaware County Memorial Hospital
 Nabila Chowdhury Ph: 610-284-8237
  Email: jolene.garney@crozer.org
  Easton
 Easton Regional Cancer Center at Easton Hospital
 Sonyo Shin Ph: 610-250-4000
  Ephrata
 Ephrata Cancer Center at Ephrata Community Hospital
 Allison Zibelli Ph: 215-955-6084
  Gettysburg
 Adams Cancer Center
 Amir Tabatabai Ph: 877-441-7957
  Hanover
 Cherry Tree Cancer Center
 Amir Tabatabai Ph: 877-441-7957
  Hazleton
 Geisinger Hazleton Cancer Center
 Victor Gerald Vogel Ph: 570-271-5251
  Hershey
 Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center
 Cristina I. Truica Ph: 410-601-6120
  Email: CTO@hmc.psu.edu
  Lancaster
 Lancaster General Hospital
 Elizabeth Horenkamp Ph: 717-544-5511
  Media
 Riddle Memorial Hospital Cancer Center
 Allison Zibelli Ph: 215-955-6084
  Monroeville
 Forbes Regional Hospital
 Thomas B Julian Ph: 877-284-2000
  Natrona Heights
 Alle-Kiski Medical Center
 Thomas B Julian Ph: 877-284-2000
  Paoli
 Cancer Center of Paoli Memorial Hospital
 Albert S DeNittis Ph: 866-225-5654
  Philadelphia
 Fox Chase Cancer Center - Philadelphia
 Lori J. Goldstein Ph: 215-728-4790
 Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
 Allison Zibelli Ph: 215-955-6084
  Phoenixville
 Cancer Center at Phoenixville Hospital
 Carl W. Sharer Ph: 610-983-1908
  Pittsburgh
 Allegheny Cancer Center at Allegheny General Hospital
 Thomas B Julian Ph: 877-284-2000
 Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
 Thomas B Julian Ph: 877-284-2000
  Reading
 St. Joseph Medical Center
 Marc Rovito Ph: 610-378-2336
  Email: danielward2@catholichealth.net
  Sayre
 Guthrie Cancer Center at Guthrie Clinic Sayre
 Cynthia A Lynch Ph: 800-836-0388
  Scranton
 Mercy Hospital Cancer Center - Scranton
 Martin B. Hyzinski Ph: 570-558-3020
 Scranton Hematology Oncology
 Martin B. Hyzinski Ph: 570-558-3020
  State College
 Geisinger Medical Group - Scenery Park
 Victor Gerald Vogel Ph: 570-271-5251
  Upland
 Associates in Hematology-Oncology, PC at Crozer Regional Cancer Center
 Allison Zibelli Ph: 215-955-6084
  West Chester
 Cancer Center of Chester County
 William E. Luginbuhl Ph: 610-431-5297
  West Reading
 McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center
 Terrence P. Cescon Ph: 610-988-9323
  Wilkes-Barre
 Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
 Victor Gerald Vogel Ph: 570-271-5251
  Williamsport
 Susquehanna Cancer Center at Divine Providence Hospital
 Warren L Robinson Ph: 800-598-4282
  Wynnewood
 CCOP - Main Line Health
 Albert S DeNittis Ph: 866-225-5654
 Lankenau Cancer Center at Lankenau Hospital
 Albert S DeNittis Ph: 866-225-5654
  York
 WellSpan Health
 Amir Tabatabai Ph: 877-441-7957
South Carolina
  Anderson
 AnMed Cancer Center
 James Dewitt Bearden Ph: 800-486-5941
  Charleston
 Hollings Cancer Center at Medical University of South Carolina
 Rita M Kramer Ph: 843-792-9321
  Easley
 Cancer Centers of the Carolinas - Easley
 Jeffrey Kent Giguere Ph: 864-241-6251
  Florence
 McLeod Regional Medical Center
 Rajesh Bajaj Ph: 843-679-7256
  Greenville
 Bon Secours St. Francis Health System
 James Dewitt Bearden Ph: 800-486-5941
 Cancer Centers of the Carolinas - Andrews
 Jeffrey Kent Giguere Ph: 864-241-6251
 Cancer Centers of the Carolinas - Faris Road
 Jeffrey Kent Giguere Ph: 864-241-6251
 Cancer Centers of the Carolinas - Grove Commons
 Jeffrey Kent Giguere Ph: 864-241-6251
 CCOP - Greenville
 Jeffrey Kent Giguere Ph: 864-241-6251
 Greenville Memorial Hospital
 Jeffrey Kent Giguere Ph: 864-241-6251
  Greenwood
 Self Regional Cancer Center at Self Regional Medical Center
 Joanna K Metzner-Sadurski Ph: 864-725-4771
  Greer
 Cancer Centers of the Carolinas - Greer Medical Oncology
 Jeffrey Kent Giguere Ph: 864-241-6251
  Seneca
 Cancer Centers of the Carolinas - Seneca
 Jeffrey Kent Giguere Ph: 864-241-6251
  Spartanburg
 Cancer Centers of the Carolinas - Spartanburg
 Jeffrey Kent Giguere Ph: 864-241-6251
 CCOP - Upstate Carolina
 James Dewitt Bearden Ph: 800-486-5941
 Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
 James Dewitt Bearden Ph: 800-486-5941
South Dakota
  Aberdeen
 Conklin Regional Cancer Center
 Richard J. Conklin Ph: 605-622-5613
  Rapid City
 Rapid City Regional Hospital
 Mark T Schroeder Ph: 605-716-3982
  Email: research@rcrh.org
  Sioux Falls
 Avera Cancer Institute
 Amy K Krie Ph: 800-657-4377
  Email: Jan.Healy@avera.org
 Sanford Cancer Center at Sanford USD Medical Center
 Miroslaw A Mazurczak Ph: 605-328-1367
 Miroslaw A Mazurczak Ph: 605-328-1367
Tennessee
  Chattanooga
 Erlanger Cancer Center at Erlanger Hospital - Baroness
 Donald H. Chamberlain Ph: 423-698-2050
  Franklin
 Vanderbilt-Ingram Cancer Center - Cool Springs
 Julie A Means-Powell Ph: 800-811-8480
  Knoxville
 Thompson Cancer Survival Center
 Antony J Charles Ph: 865-541-1812
 U.T. Medical Center Cancer Institute
 Timothy John Panella Ph: 865-544-9773
  Nashville
 MBCCOP - Meharry Medical College - Nashville
 Philip E Lammers Ph: 615-327-5724
  Email: jmurray@mmc.edu
 Nashville Breast Center
 John J Murray Ph: 615-327-5724
  Email: jmurray@mmc.edu
 Vanderbilt Breast Center at One Hundred Oaks
 Julie A Means-Powell Ph: 800-811-8480
 Vanderbilt-Ingram Cancer Center
 Julie A Means-Powell Ph: 800-811-8480
Texas
  Amarillo
 Harrington Cancer Center
 Brian T. Pruitt Ph: 806-359-4673
  Email: ryokubaitis@harringtoncc.org
  Houston
 Univeristy of Texas M.D. Anderson Cancer Center
 Stacy L. Moulder Ph: 713-792-3245
  Laredo
 Doctor's Hospital of Laredo
 Gary W. Unzeitig Ph: 888-823-5923
  Email: ctsucontact@westat.com
  Lubbock
 Covenant Medical Center
 Ibrahim A Shalaby Ph: 806-725-8000
  Email: jaccresearch@covhs.org
 Texas Tech University Health Sciences Center
 Diane D Nguyen Ph: 806-775-8590
  San Antonio
 Cancer Therapy and Research Center
 Anand B. Karnad Ph: 210-616-5798
 University of Texas Health Science Center at San Antonio
 Anand B. Karnad Ph: 210-616-5798
Utah
  Salt Lake City
 Huntsman Cancer Institute at University of Utah
 Anna C Beck Ph: 801-581-4477
  Email: clinical.trials@hci.utah.edu
Virginia
  Burke
 Kaiser Permanente at Burke Medical Center
 Leon C. Hwang Ph: 301-816-7446
  Fairfax
 Medical Oncology and Hematology Associates of North Virginia - Fairfax
 Mary J Wilkinson Ph: 703-720-5210ext1044
  Fishersville
 Augusta Medical Center Cancer Center
 Patrick H. Judson Ph: 540-245-7106
  Fredericksburg
 Fredericksburg Oncology Inc
 Rex B Mowat Ph: 517-265-0116
  McLean
 Kaiser Permanente Tysons Corner Medical Center
 Leon C. Hwang Ph: 301-816-7446
  Richmond
 Virginia Commonwealth University Massey Cancer Center
 Harry D. Bear Ph: 804-628-1939
Washington
  Anacortes
 Cancer Care Center at Island Hogs
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Auburn
 Auburn Regional Center for Cancer Care
 Yoshio Inoue Ph: 253-403-2394
  Bellevue
 Overlake Cancer Center at Overlake Hospital Medical Center
 Yoshio Inoue Ph: 253-403-2394
  Bellingham
 St. Joseph Cancer Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Bremerton
 Olympic Hematology and Oncology
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Burien
 Highline Medical Center Cancer Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Centralia
 Providence Centralia Hospital
 Yoshio Inoue Ph: 253-403-2394
  Edmonds
 Swedish Cancer Institute at Stevens Hospital
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Everett
 Providence Regional Cancer Partnership
 Yoshio Inoue Ph: 253-403-2394
  Federal Way
 St. Francis Hospital
 Yoshio Inoue Ph: 253-403-2394
  Issaquah
 Swedish Medical Center - Issaquah Campus
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Kennewick
 Columbia Basin Hematology
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Kirkland
 Cascade Cancer Center at Evergreen Hospital Medical Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Mount Vernon
 Skagit Valley Hospital Cancer Care Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Olympia
 Providence St. Peter Hospital Regional Cancer Center
 Yoshio Inoue Ph: 253-403-2394
  Poulsbo
 Harrison Poulsbo Hematology and Onocology
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Puyallup
 Good Samaritan Cancer Center
 Yoshio Inoue Ph: 253-403-2394
  Seattle
 Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Group Health Central Hospital
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Harborview Medical Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Minor and James Medical, PLLC
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 University Cancer Center at University of Washington Medical Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Sedro-Woolley
 North Puget Oncology at United General Hospital
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Spokane
 Cancer Care Northwest - Spokane South
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Evergreen Hematology and Oncology, PS
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
 Rockwood Clinic Cancer Treatment Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
  Tacoma
 Allenmore Hospital
 Yoshio Inoue Ph: 253-403-2394
 CCOP - Northwest
 Yoshio Inoue Ph: 253-403-2394
 Franciscan Cancer Center at St. Joseph Medical Center
 Yoshio Inoue Ph: 253-403-2394
 MultiCare Regional Cancer Center at Tacoma General Hospital
 Yoshio Inoue Ph: 253-403-2394
 St. Clare Hospital
 Yoshio Inoue Ph: 253-403-2394
  Vancouver
 Legacy Salmon Creek Medical Center
 Jacqueline Vuky Ph: 503-299-6500
 Northwest Cancer Specialists at Vancouver Cancer Center
 Alison K Conlin Ph: 503-215-6412
 Southwest Washington Medical Center Cancer Center
 Alison K Conlin Ph: 503-215-6412
  Wenatchee
 Confluence Health - Wenatchee Valley Medical Center
 Gary E Goodman Ph: 206-386-2323
  Email: patra.grevstad@swedish.org
West Virginia
  Charleston
 West Virginia University Medical School - Charleston
 Steven J. Jubelirer Ph: 304-388-9944
  Huntington
 St. Mary's Regional Cancer Center at St. Mary's Medical Center
 Arvinder S Bir Ph: 888-823-5923
  Email: ctsucontact@westat.com
Wisconsin
  Chippewa Falls
 Marshfield Clinic - Chippewa Center
 Bilal H Naqvi Ph: 800-839-3956
  Eau Claire
 Marshfield Clinic Cancer Care at Regional Cancer Center
 Bilal H Naqvi Ph: 800-839-3956
  Green Bay
 Green Bay Oncology, Limited at St. Mary's Hospital
 Matthew L Ryan Ph: 800-432-6049
 Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
 Matthew L Ryan Ph: 800-432-6049
 St. Mary's Hospital Medical Center - Green Bay
 Matthew L Ryan Ph: 800-432-6049
 St. Vincent Hospital Regional Cancer Center
 Matthew L Ryan Ph: 800-432-6049
 Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
 Rubina Qamar Ph: 888-709-2080
  Janesville
 Mercy Regional Cancer Center
 Robert Delaune Ph: 800-928-1103
  Johnson Creek
 UW Cancer Center Johnson Creek
 Mark E Burkard Ph: 877-405-6866
  Madison
 Dean Hematology & Oncology Clinic
 Amit Sanyal Ph: 608-410-2700
 University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
 Mark E Burkard Ph: 877-405-6866
  Manitowoc
 Holy Family Memorial Medical Center Cancer Care Center
 Matthew L Ryan Ph: 800-432-6049
  Marinette
 Bay Area Cancer Care Center at Bay Area Medical Center
 Matthew L Ryan Ph: 800-432-6049
 Vince Lombardi Cancer Clinic - Marinette
 Rubina Qamar Ph: 888-709-2080
  Marshfield
 Marshfield Clinic - Marshfield Center
 Bilal H Naqvi Ph: 800-839-3956
  Mequon
 Columbia Saint Mary's Hospital - Ozaukee
 Charles H. I. Tiber Ph: 414-326-2675
  Email: clinicaltrials@columbia-stmarys.org
  Milwaukee
 Columbia-Saint Mary's Cancer Care Center
 Charles H. I. Tiber Ph: 414-326-2675
  Email: clinicaltrials@columbia-stmarys.org
 Wheaton Franciscan Cancer Care - St. Joseph
 Francis J Cuevas Ph: 414-874-4541
  Minocqua
 Marshfield Clinic - Lakeland Center
 Bilal H Naqvi Ph: 800-839-3956
  Mukwonago
 D.N. Greenwald Center
 Timothy R Wassenaar Ph: 262-928-7878
  New Richmond
 Cancer Center of Western Wisconsin
 Patrick J. Flynn Ph: 952-993-1517
  Email: MMCCOP@parknicollet.com
  Oconomowoc
 Regional Cancer Center at Oconomowoc Memorial Hospital
 Timothy R Wassenaar Ph: 262-928-7878
  Oconto Falls
 Green Bay Oncology, Limited - Oconto Falls
 Matthew L Ryan Ph: 800-432-6049
  Oshkosh
 Vince Lombardi Cancer Clinic - Oshkosh
 Rubina Qamar Ph: 888-709-2080
  Rhinelander
 Ministry Medical Group at Saint Mary's Hospital
 Bilal H Naqvi Ph: 800-839-3956
  Rice Lake
 Marshfield Clinic - Indianhead Center
 Bilal H Naqvi Ph: 800-839-3956
  Sheboygan
 Saint Nicholas Hospital
 Matthew L Ryan Ph: 800-432-6049
 Vince Lombardi Cancer Clinic - Sheboygan
 Rubina Qamar Ph: 888-709-2080
  Stevens Point
 Marshfield Clinic at Saint Michael's Hospital
 Bilal H Naqvi Ph: 800-839-3956
  Sturgeon Bay
 Green Bay Oncology, Limited - Sturgeon Bay
 Matthew L Ryan Ph: 800-432-6049
  Summit
 Aurora Medical Center
 Rubina Qamar Ph: 888-709-2080
  Two Rivers
 Vince Lombardi Cancer Clinic - Two Rivers
 Rubina Qamar Ph: 888-709-2080
  Waukesha
 Waukesha Memorial Hospital Regional Cancer Center
 Timothy R Wassenaar Ph: 262-928-7878
  Wausau
 Marshfield Clinic - Wausau Center
 Bilal H Naqvi Ph: 800-839-3956
  Wauwatosa
 Oncology Alliance, SC - Milwaukee - West
 Rubina Qamar Ph: 888-709-2080
  Weston
 Marshfield Clinic - Weston Center
 Bilal H Naqvi Ph: 800-839-3956
  Wisconsin Rapids
 Marshfield Clinic - Wisconsin Rapids Center
 Bilal H Naqvi Ph: 800-839-3956
Wyoming
  Casper
 Rocky Mountain Oncology
 Benjamin Thomas Marchello Ph: 800-648-6274
  Sheridan
 Welch Cancer Center at Sheridan Memorial Hospital
 Benjamin Thomas Marchello Ph: 800-648-6274

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01674140
ClinicalTrials.gov processed this data on January 30, 2014

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.

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