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NCI Dictionary of Cancer Terms


familial atypical multiple mole melanoma syndrome  listen  (fuh-MIH-lee-ul AY-TIH-pih-kul MUL-tih-pul ... MEH-luh-NOH-muh SIN-drome)

  An inherited condition marked by the following: (1) one or more first- or second-degree relatives (parent, sibling, child, grandparent, grandchild, aunt, or uncle) with malignant melanoma; (2) many moles, some of which are atypical (asymmetrical, raised, and/or different shades of tan, brown, black, or red) and often of different sizes; and (3) moles that have specific features when examined under a microscope. Familial atypical multiple mole melanoma syndrome increases the risk of melanoma and may increase the risk of pancreatic cancer. Also called FAMMM syndrome.