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NCI Dictionary of Cancer Terms


Avastin  listen  (uh-VAS-tin)

  A drug used alone or with other drugs to treat certain types of cervical, colorectal, lung, kidney, ovarian, fallopian tube, and primary peritoneal cancer, and glioblastoma (a type of brain cancer). It is also being studied in the treatment of other types of cancer. Avastin binds to a protein called vascular endothelial growth factor (VEGF). This may prevent the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent and a type of monoclonal antibody. Also called bevacizumab.

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