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NCI Dictionary of Cancer Terms


LSIL   

  Slightly abnormal cells are found on the surface of the cervix. LSIL is caused by certain types of human papillomavirus (HPV) and is a common abnormal finding on a Pap test. It usually goes away on its own without treatment but sometimes the abnormal cells become cancer and spread to nearby normal tissue. LSIL is sometimes called mild dysplasia. Also called low-grade squamous intraepithelial lesion.

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Cervical changes; drawing shows a cross-section of the uterus, cervix, and vagina. Also shown are four panels showing cell changes inside the cervix. The first panel shows normal cells. The second and third panels show abnormal cells called LSIL and HSIL. The fourth panel shows cervical cancer cells. Arrows are used between the panels to show that normal cells may become LSIL or HSIL, which may or may not become cancer.