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NCI Dictionary of Cancer Terms

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NCI Dictionary of Cancer Terms

tumor vasculature–targeted tumor necrosis factor alpha  listen  (TOO-mer VAS-kyoo-luh-cher-TAR-geh-ted TOO-mer neh-KROH-sis FAK-ter AL-fuh)

  A substance being studied in the treatment of cancer. It is made by linking tumor necrosis factor (TNF) to a peptide. The peptide binds to tumor blood vessels, and TNF damages them. It is a type of biological response modifier. Also called NGR-TNF.