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NCI Dictionary of Cancer Terms

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NCI Dictionary of Cancer Terms



17-N-allylamino-17-demethoxygeldanamycin  listen  (17-N-A-lul-uh-MEE-noh-17-DEE-meh-THOK-see-gel-DA-nuh-MY-sin)

  A substance being studied in the treatment of cancer. It is made from an antibiotic called geldanamycin. 17-N-allylamino-17-demethoxygeldanamycin helps cause the breakdown of certain proteins in the cell, and may kill cancer cells. It is a type of antineoplastic antibiotic and a type of HSP90 inhibitor. Also called 17-AAG and tanespimycin.