NCI Dictionary of Cancer Terms
The search textbox has an autosuggest feature. When you enter three or more characters, a list of up to 10 suggestions will popup under the textbox. Use the arrow keys to move through the suggestions. To select a suggestion, hit the enter key. Using the escape key closes the listbox and puts you back at the textbox. The radio buttons allow you to toggle between having all search items start with or contain the text you entered in the search box.
A drug used to treat a rare condition called Castleman disease in patients who do not have HIV or human herpesvirus 8. It is also being studied in the treatment of multiple myeloma. CNTO 328 binds to a protein called interleukin-6 (IL-6), which is made by some white blood cells and other cells in the body. CNTO 328 may help reduce inflammation and stop the growth of cancer cells or abnormal blood cells. It is a type of monoclonal antibody. Also called anti-IL-6 chimeric monoclonal antibody, cCLB8, siltuximab, and Sylvant.