NCI Dictionary of Cancer Terms
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Dukes A colorectal cancer (dooks ... KOH-loh-REK-tul KAN-ser)
Cancer has spread from the mucosa (innermost layer) of the colon and/or rectal wall to the submucosa (layer of tissue under the mucosa) of the colon and/or rectal wall. Cancer may have spread to the muscle layer of the colon and/or rectal wall. Also called stage I colorectal cancer.