NCI Dictionary of Cancer Terms
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anti-IL-6 chimeric monoclonal antibody (AN-tee ... ky-MEER-ik MAH-noh-KLOH-nul AN-tee-BAH-dee)
A drug used to treat a rare condition called Castleman disease in patients who do not have HIV or human herpesvirus 8. It is also being studied in the treatment of multiple myeloma. Anti-IL-6 chimeric monoclonal antibody binds to a protein called interleukin-6 (IL-6), which is made by some white blood cells and other cells in the body. Anti-IL-6 chimeric monoclonal antibody may help reduce inflammation and stop the growth of cancer cells or abnormal blood cells. It is a type of monoclonal antibody. Also called cCLB8, CNTO 328, siltuximab, and Sylvant.