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NCI Dictionary of Cancer Terms


anti-VEGFR monoclonal antibody  listen  (AN-tee … MAH-noh-KLOH-nul AN-tee-BAH-dee)

  A substance that binds to receptors for a protein called vascular endothelial growth factor (VEGF), which may be found on some types of cancer cells. This may prevent the growth of new blood vessels that tumors need to grow. There are different types of anti-VEGFR monoclonal antibodies being studied in the treatment of cancer. These substances are a type of antiangiogenesis agent and a type of monoclonal antibody.