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NCI Dictionary of Cancer Terms


[18F]-labeled substance P antagonist receptor quantifier  listen  (… LAY-buld SUB-stunts P an-TA-guh-nist reh-SEP-ter KWAN-tih-FY-er)

  A radiolabeled substance being studied in PET imaging of the brain. It is also being studied as a way to find where cancer cells have spread in patients with pancreatic cancer. It binds to cell receptors for substance P, also known as neurokinin-1, which is found on nerve cells and on some types of cancer cells, such as pancreatic cancer cells. [18F]-labeled substance P antagonist receptor quantifier is a type of PET radioligand and a type of radiolabeled neurokinin-1 receptor antagonist.