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NCI Dictionary of Cancer Terms

TRAIL receptor 1  listen  (… reh-SEP-ter 1)

  A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the amount or activity of TRAIL receptor 1 on cancer cells may kill more cells. Also called death receptor 4, DR4, TRAIL-R1, and tumor necrosis factor receptor superfamily member 10A.