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NCI Dictionary of Cancer Terms

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ramucirumab  listen  (RA-myoo-SIR-yoo-mab)

  A substance being studied in the treatment of several types of cancer, including stomach, esophageal, breast, urinary tract, and non-small cell lung cancer. Ramucirumab binds to receptors for a protein called vascular endothelial growth factor (VEGF), which may be found on some types of cancer cells. This may prevent the growth of new blood vessels that tumors need to grow. Ramucirumab is a type of antiangiogenesis agent and a type of monoclonal antibody. Also called anti-VEGFR-2 fully human monoclonal antibody IMC-1121B and IMC-1121B.