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NCI Dictionary of Cancer Terms

urokinase-plasminogen activator  listen  (YOOR-oh-KY-nays-plaz-MIH-noh-jen AK-tih-vay-ter)

  An enzyme that is made in the kidney and found in the urine. A form of this enzyme is made in the laboratory and used to dissolve blood clots or to prevent them from forming. Also called u-plasminogen activator, uPA, and urokinase.