NCI Dictionary of Cancer Terms
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A drug used with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (IL-2), and 13-cis-retinoic acid to treat high-risk neuroblastoma. It is used in children whose disease has improved with other anticancer treatment. MOAB Ch14.18 binds to a substance called GD2, which is found on some types of cancer cells. MOAB Ch14.18 may block GD2 and help the immune system kill cancer cells. It is a type of monoclonal antibody. Also called Ch14.18, dinutuximab, monoclonal antibody Ch14.18, and Unituxin.