NCI Dictionary of Cancer Terms
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brentuximab vedotin (bren-TUK-sih-mab veh-DOH-tin)
A drug used to treat Hodgkin lymphoma and systemic anaplastic large cell lymphoma that did not get better with other treatment. It is also being studied in the treatment of other types of lymphoma. Brentuximab vedotin is made by combining a monoclonal antibody with an anticancer drug. It binds to a protein called CD30, which is on the surface of some lymphoma cells, and may kill cancer cells. Brentuximab vedotin is a type of antibody-drug conjugate. Also called Adcetris and SGN-35.