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NCI Drug Dictionary

NCI Drug Dictionary

  

yttrium Y 90 ibritumomab tiuxetan 
A radioimmunotherapeutic agent consisting of a murine monoclonal anti-CD20 antibody (ibritumomab) linked by the chelator tiuxetan to the radioisotope yttrium-90 (Y 90). Yttrium Y 90 ibritumomab tiuxetan binds to and specifically delivers beta radiation to CD20-expressing tumor cells, thereby minimizing the systemic effects of radiation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:90Y ibritumomab tiuxetan
Ibritumomab (In2B8/Y2B8 radiolabeling kit)
ibritumomab tiuxetan
IDEC-Y2B8 monoclonal antibody
Y90 Zevalin
Y90-labeled ibritumomab tiuxetan
Yttrium-90 ibritumomab tiuxetan
US brand name:Zevalin
Code name:IDEC Y2B8