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NCI Drug Dictionary


anti-IL-13 humanized monoclonal antibody TNX-650 
A humanized monoclonal antibody directed against interleukin-13 (IL-13) with potential antineoplastic activity. Anti-IL-13 humanized monoclonal antibody TNX-650 binds to and blocks the activity of IL-13, which may result in the inhibition of Hodkin lympoma cell proliferation. IL-13 cytokine, an important mediator in allergic inflammation, may be an autocrine growth factor for Hodgkin lymphoma cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:monoclonal antibody TNX-650
Code name:TNX-650