NCI Drug Dictionary
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D1/3-MAGE-3-His fusion protein
A recombinant fusion protein derived from the melanoma antigen MAGE-3 with potential immunostimulating and antineoplastic activities. Recognized by specific cytotoxic T lymphocytes, D1/3-MAGE-3-His fusion protein may boost antitumoral immune responses when used in a vaccine formulation. This recombinant chimeric protein is produced by fusing MAGE-3 with a lipidated protein D derived from H. influenzae at its N-terminus and a sequence of several histidine residues at its C-terminus. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||D1/3-Mage-3 Fusion Protein |
D1/3-Mage-3 Fusion Protein (SB MAGE-3)
|Abbreviation:||D1/3 MAGE3 HIS|
|Code name:||GSK 2132231A|