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NCI Drug Dictionary


golnerminogene pradenovec 
A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:adenovirus 5-tumor necrosis factor alpha
tumor necrosis factor adenovirus 5 vector
US brand name:TNFerade
Abbreviations:Ad 5-TNF Alpha
Code name:ADgv EGR.TNF.11D