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NCI Drug Dictionary


rasburicase  Patient Information
A recombinant urate oxidase enzyme isolated from a genetically-modified strain of Saccharomyces cerevisae. Urate oxidase catalyzes the oxidation of uric acid to the excretable mebolite allantoin, a molecule that is 5-10 times more water-soluble than uric acid. An enzyme that occurs endogenously in most mammals, urate oxidase is not found in humans. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:recombinant urate oxidase
Urate Oxidase
US brand name:Elitek
Code names:NK-631