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NCI Drug Dictionary


A monoclonal antibody with potential antineoplastic activity. Iratumumab is a fully humanized antibody that targets CD30, a member of the tumor necrosis factor receptor superfamily found on activated lymphocytes. CD30 is over-expressed in various lymphoproliferative disorders, Hodgkin's disease and other lymphomas, and other cancers. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
monoclonal antibody MDX-060