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NCI Drug Dictionary


liposomal daunorubicin citrate 
A liposome-encapsulated form of the citrate salt of the anthracycline antineoplastic antibiotic daunorubicin. Daunorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Liposomal delivery of doxorubicin citrate improves drug penetration into tumors and decreases drug clearance, thereby increasing the duration of therapeutic drug effects. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:daunorubicin liposomal
liposomal daunorubicin
US brand name:DaunoXome