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NCI Drug Dictionary


bispecific antibody MDX447 
An antibody with potential antineoplastic activity. Specific for both the high-affinity immunoglobulin G (IgG) receptor CD64 and epidermal growth factor receptor (EGFR), bispecific antibody MDX447 may enhance cellular immune responses against EGFR positive cells, resulting in increased tumor cell lysis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:BsAb MDX447
Code names:EMD 82633