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NCI Drug Dictionary


yttrium Y 90 monoclonal antibody BrE-3 
A radioimmunotherapeutic agent consisting of a monoclonal antibody (BrE-3) directed against the tumor-associated antigen epithelial glycoprotein mucin chelated to the radioisotope yttrium-90. Yttrium Y 90 monoclonal antibody BrE-3 binds to tumor cells expressing epithelial glycoprotein mucin, selectively delivering a cytotoxic dose of beta radiation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:BrE-3 monoclonal antibody, yttrium Y 90
MOAB BrE-3, yttrium Y 90
Y90 monoclonal antibody BrE-3
Abbreviation:Y90 MOAB BrE-3