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NCI Drug Dictionary


One of a number of a class of sphingolipids, N-acyl derivatives with long chains. Ceramide is the core molecule for the synthesis of sphingomyelin, an essential lipid for myelination and neurotransmission; it may function as a second messenger to stimulate differentiation, inhibit proliferation, and induce apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:Ceramide (lipids)
Chemical structure:N-Acyl Sphingosine