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NCI Drug Dictionary


DC-cholesterol liposome 
A cationic cholesterol derivative mixed with dimethylaminoethane-carbamoyl and sonicated to form small unilamellar vesicles that can complex with DNA, DNA/protein complexes and other drug complexes and mediates the delivery into the cytosol from the endosome compartment. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Abbreviations:DC-CHOL LIP
DC-chol liposomes
Chemical structure:dimethylaminoethane-carbamoyl-cholesterol liposomes