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The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand name:||Zoladex|
|Chemical structure:||6-[O-(1,1-dimethylethyl)-D-serine]-10-deglycinamide luteinizing hormone-releasing factor (pig) 2-(aminocarbonyl)hydrazide|