In English | En español
Questions About Cancer? 1-800-4-CANCER

NCI Drug Dictionary

NCI Drug Dictionary

  

recombinant macrophage colony-stimulating factor 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine macrophage colony-stimulating factor (M-CSF). Synthesized endogenously by mesenchymal cells, M-CSF stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series and can reverse treatment-related neutropenias. Recombinant M-CSF may also enhance antigen presentation and activate antitumoral cytotoxic T-cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:colony stimulating factor 1
recombinant colony-stimulating factor 1
Abbreviation:rM-CSF