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NCI Drug Dictionary

  

mifepristone 
A derivative of the synthetic progestin norethindrone with antiprogesterone activity. Mifepristone competitively binds to the progesterone receptor, resulting in inhibition of the effects of endogenous or exogenous progesterone. This agent also exhibits antiglucocorticoid and weak antiandrogenic activities. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Mifeprex
Foreign brand name:Mifegyne
Code names:RU 486
RU-38486
Chemical structures:(aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
11 beta-[4-(N,N-dimethylamino)phenyl]-17alpha-(propyl-1-ynyl)-delta-4,9-estradiene-17 beta-ol-3-one
11-((4-dimethylamino) phenyl)-17-Hydroxy-17-(1-propynyl) estra-4,9- dien-3-one