NCI Drug Dictionary
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A recombinant, non-glycosylated cytokine which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF) isoform B, with immunomodulating activity. Filgrastim binds to and activates G-CSF receptors with the same biological activity and stability as the endogenous cytokine, thereby controlling the production, differentiation, and function of neutrophilic granulocyte progenitors. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||filgrastim XM02 |
granulocyte colony-stimulating factor
Recombinant Methionyl Human Granulocyte Colony Stimulating Factor
|US brand names:||Neupogen |
|Foreign brand name:||Nivestim|