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NCI Drug Dictionary

NCI Drug Dictionary

  

monoclonal antibody 14G2A 
A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:14G2A
14G2A, monoclonal antibody
antibody 14G2A, monoclonal
Abbreviation:MOAB 14G2A