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NCI Drug Dictionary


liposomal interleukin-2 
A formulation in which liposomes are loaded with the cytokine interleukin-2 (IL-2). By activating cytotoxic T lymphocytes, such as lymphokine-activated killer cells, and increasing levels of the cytotoxic cytokines interferon-gamma (IFN-gamma) and transforming growth factor-beta (TGF-beta), IL-2 may exhibit antitumoral activity. Liposomal formulations of IL-2 may promote entry of the cytokine into target tumor cells and may be used as an immunoadjuvant in cancer vaccine therapy. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:interleukin-2 liposome
liposome encapsulated interleukin-2
Abbreviation:IL-2 LIPO