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NCI Drug Dictionary


A chimeric monoclonal antibody with potential antineoplastic activity. Volociximab binds to and inhibits the activity of alpha(5)beta(1) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:anti-alpha 5 beta 1 integrin monoclonal antibody
anti-α5β1 integrin
Abbreviation:anti-α5β1 integrin MOAB
Code name:M200